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References from Genome-wide identification and expression analysis of lysine-specific demethylase (KDM) genes in the echiuran worm Urechis unicinctus and the association of Jumonji domain containing 6 (Jmjd6) with antioxidant defense. Local targets link to admitted publications; unresolved targets remain external evidence.
Jumonji domain containing protein 6: a novel oxygen sensor in the human placenta
10.1210/en.2015-1262 · 2015 · External reference
An HSF1–JMJD6–HSP feedback circuit promotes cell adaptation to proteotoxic stress
10.1073/pnas.2313370121 · 2024 · External reference
The ferric reducing ability of plasma (FRAP) as a measure of “antioxidant power”: the FRAP assay
10.1006/abio.1996.0292 · 1996 · External reference
Oxidative stress and antioxidant defense
10.1097/wox.0b013e3182439613 · 2012 · External reference
Histone lysine methylation dynamics: establishment, regulation, and biological impact
10.1016/j.molcel.2012.11.006 · 2012 · External reference
The oxygenase Jmjd6-a case study in conflicting assignments
10.1042/bj20150278 · 2015 · External reference
JMJD6 is a histone arginine demethylase
10.1126/science.1145801 · 2007 · External reference
Identification and validation of the reference genes in the echiuran worm Urechis unicinctus based on transcriptome data
10.1186/s12864-023-09358-6 · 2023 · External reference
TBtools-II: a "one for all, all for one" bioinformatics platform for biological big-data mining
10.1016/j.molp.2023.09.010 · 2023 · External reference
Specific phosphorylation of histone demethylase KDM3A determines target gene expression in response to heat shock
10.1371/journal.pbio.1002026 · 2014 · External reference
Epigenetic regulation of stress responses in plants
10.1016/j.pbi.2008.12.006 · 2009 · External reference
Conservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans
10.1038/s41598-022-10028-y · 2022 · External reference
The environmental cellular stress response: the intertidal as a multistressor model
10.1007/s12192-023-01348-7 · 2023 · External reference
Profiling inhibitor scaffolds for the cancer target Jumonji-C domain-containing protein 6
10.1002/cmdc.202500682 · 2025 · External reference
Metabolic control of histone demethylase activity involved in plant response to high temperature
10.1093/plphys/kiab020 · 2021 · External reference
Acute ammonia stress-induced oxidative and heat shock responses modulated by transcription factors in Litopenaeus vannamei
10.1016/j.fsi.2022.07.060 · 2022 · External reference
Multiple exposures to drought 'train' transcriptional responses in Arabidopsis
10.1038/ncomms1732 · 2012 · External reference
Exploring the innate immune system of Urechis unicinctus: insights from full-length transcriptome analysis
10.1016/j.gene.2024.148784 · 2024 · External reference
Histone methylation and memory of environmental stress
10.3390/cells8040339 · 2019 · External reference
The Jumonji gene family in Crassostrea gigas suggests evolutionary conservation of Jmj-C histone demethylases orthologues in the oyster gametogenesis and development
10.1016/j.gene.2013.12.016 · 2014 · External reference
Temperature influences histone methylation and mRNA expression of the Jmj-C histone-demethylase orthologues during the early development of the oyster Crassostrea gigas
10.1016/j.margen.2014.09.002 · 2015 · External reference
The Kdm/Kmt gene families in the self-fertilizing mangrove rivulus fish, Kryptolebias marmoratus, suggest involvement of histone methylation machinery in development and reproduction
10.1016/j.gene.2018.11.046 · 2019 · External reference
Identification of DNA (de)methylation-related genes and their transcriptional response to environmental challenges in an invasive model ascidian
10.1016/j.gene.2020.145331 · 2021 · External reference
The histone demethylase dKDM5/LID interacts with the SIN3 histone deacetylase complex and shares functional similarities with SIN3
10.1186/s13072-016-0053-9 · 2016 · External reference
Histone methylation: a dynamic mark in health, disease and inheritance
10.1038/nrg3173 · 2012 · External reference
Expression profiling of the Kdm genes in scallop Patinopecten yessoensis suggests involvement of histone demethylation in regulation of early development and gametogenesis
2020 · External reference
Genomic structure and expression of Jmjd6 and evolutionary analysis in the context of related JmjC domain containing proteins
10.1186/1471-2164-9-293 · 2008 · External reference
Harnessing antioxidants for abiotic stress management: mechanistic insights and prospects for sustainable agriculture
10.3390/antiox15030337 · 2026 · External reference
Effects of temperature changes on life parameters, oxidative stress, and antioxidant defense system in the monogonont marine rotifer Brachionus plicatilis
10.1016/j.marpolbul.2020.111062 · 2020 · External reference
Epigenetic regulation by histone demethylases in hypoxia
10.2217/epi.15.24 · 2015 · External reference
Decoding JMJD proteins in cardiovascular and cerebrovascular diseases: from structure to function
10.1016/j.arr.2025.102869 · 2025 · External reference
Glutathione transferases
10.1146/annurev.pharmtox.45.120403.095857 · 2005 · External reference
Photoperoxidation in isolated chloroplasts. I. Kinetics and stoichiometry of fatty acid peroxidation
10.1016/0003-9861(68)90654-1 · 1968 · External reference
Arabidopsis histone H3K4 demethylase JMJ17 functions in dehydration stress response
10.1111/nph.15874 · 2019 · External reference
First line defence antioxidants-superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX): their fundamental role in the entire antioxidant defence grid
2018 · External reference
The fluorometric analysis of ultramicro quantities of hydrogen peroxide
10.1016/0003-2697(65)90034-5 · 1965 · External reference
Regulation of histone methylation by demethylimination and demethylation
10.1038/nrm2143 · 2007 · External reference
Molecular mechanisms and potential functions of histone demethylases
10.1038/nrm3327 · 2012 · External reference
Epigenetic and chromatin-based mechanisms in environmental stress adaptation and stress memory in plants
10.1186/s13059-017-1263-6 · 2017 · External reference
A hit-and-run heat shock factor governs sustained histone methylation and transcriptional stress memory
10.15252/embj.201592593 · 2016 · External reference
JMJD6 promotes self-renewal and regenerative capacity of hematopoietic stem cells
10.1182/bloodadvances.2020002702 · 2021 · External reference
Genome-wide identification and transcriptional modulation of histone variants and modification related genes in the low pH-exposed marine rotifer Brachionus koreanus
2020 · External reference
Adaptations and plastic phenotypic responses of marine animals to the environmental challenges of the high intertidal zone
2022 · External reference
Histone lysine demethylase 5 regulates haemocyte proliferation during immune priming in the oyster Crassostrea gigas
10.1016/j.fsi.2025.110236 · 2025 · External reference
Genome-wide identification of TRAF family genes in Urechis unicinctus (Annelida, Echiura) and their responses in resistance to high temperature stress
2025 · External reference
Genome-wide analyses of heat shock protein superfamily provide new insights on adaptation to sulfide-rich environments in Urechis unicinctus (Annelida, Echiura)
10.3390/ijms23052715 · 2022 · External reference
Expanding chemical biology of 2-oxoglutarate oxygenases
10.1038/nchembio0308-152 · 2008 · External reference
The thioredoxin antioxidant system
10.1016/j.freeradbiomed.2013.07.036 · 2014 · External reference
Response of sulfide: quinone oxidoreductase to sulfide exposure in the echiuran worm Urechis unicinctus
10.1007/s10126-011-9408-1 · 2012 · External reference
Crystal structure of the 2-oxoglutarate- and Fe(II)-dependent lysyl hydroxylase JMJD6
10.1016/j.jmb.2010.05.054 · 2010 · External reference
A dynamic histone-based chromatin regulatory toolkit underpins genome and developmental evolution in an invertebrate clade
10.1186/s13059-025-03626-2 · 2025 · External reference
The heat shock response: systems biology of proteotoxic stress in aging and disease
10.1101/sqb.2012.76.010637 · 2011 · External reference
The small members of the JMJD protein family: enzymatic jewels or jinxes?
2019 · External reference
Finding balance: the dynamic interplay between H3K27me3 writers and erasers in regulating environmental plasticity and memory
10.1111/nph.70815 · 2026 · External reference
Histone demethylases in development and disease
10.1016/j.tcb.2010.08.011 · 2010 · External reference
The JmjC domain histone demethylase Ndy1 regulates redox homeostasis and protects cells from oxidative stress
10.1128/mcb.00688-08 · 2008 · External reference
Genome-wide identification, evolution of histone lysine demethylases (KDM) genes and their expression during gonadal development in Nile tilapia
10.1016/j.cbpb.2021.110674 · 2022 · External reference
UuCTL6, a novel C-type lectin of Urechis unicinctus, agglutinates various bacteria and promotes immune defense against bacterial infection
10.1016/j.dci.2026.105613 · 2026 · External reference
Overview on peroxiredoxin
10.14348/molcells.2016.2368 · 2016 · External reference
Oxidative stress: a concept in redox biology and medicine
10.1016/j.redox.2015.01.002 · 2015 · External reference
Measurement of protein using bicinchoninic acid
10.1016/0003-2697(85)90442-7 · 1985 · External reference
A simple method for clinical assay of superoxide dismutase
10.1093/clinchem/34.3.497 · 1988 · External reference
Histone arginine demethylase JMJD6 is linked to stress granule assembly through demethylation of the stress granule-nucleating protein G3BP1
10.1074/jbc.m117.800706 · 2017 · External reference
KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development
10.1101/gad.1864410 · 2010 · External reference
Lysyl 5-hydroxylation, a novel histone modification, by Jumonji domain containing 6 (JMJD6)
10.1074/jbc.m112.433284 · 2013 · External reference
Discovery of a new class of JMJD6 inhibitors and structure-activity relationship study
10.1016/j.bmcl.2021.128109 · 2021 · External reference
Genome-wide identification and expression analyses of toll-like receptors provide new insights on adaptation to intertidal benthic environments in Urechis unicinctus (Annelida, Echiura)
10.1016/j.aquatox.2023.106594 · 2023 · External reference
Experimental DNA demethylation reduces expression plasticity and thermal tolerance in Pacific oysters
2023 · External reference
Kdm2a inhibition in skeletal muscle improves metabolic flexibility in obesity
10.1038/s42255-024-01210-9 · 2025 · External reference
Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing
10.1126/science.1175865 · 2009 · External reference
Echiuran Hox genes provide new insights into the correspondence between Hox subcluster organization and collinearity pattern
2022 · External reference
Identification of the principal neuropeptide MIP and its action pathway in larval settlement of the echiuran worm Urechis unicinctus
2024 · External reference
JMJD8 is a positive regulator of TNF-induced NF-κB signaling
10.1038/srep34125 · 2016 · External reference
JmjC domain-containing histone demethylase gene family in Chinese cabbage: genome-wide identification and expressional profiling
10.1371/journal.pone.0312798 · 2024 · External reference
Histone methylation in plant responses to abiotic stresses
10.1093/jxb/eraf058 · 2025 · External reference
Jumonji domain-containing protein 6 promotes gastric cancer progression: modulating immune evasion through autophagy and oxidative stress pathways
10.25259/cytojournal_230_2024 · 2025 · External reference
Epigenome screening highlights that JMJD6 confers an epigenetic vulnerability and mediates sunitinib sensitivity in renal cell carcinoma
10.1002/ctm2.328 · 2021 · External reference
Genome-wide profiling of DNA methylome and transcriptome reveals epigenetic regulation of Urechis unicinctus response to sulfide stress
10.1016/j.scitotenv.2024.172238 · 2024 · External reference
DNA methylation regulates somatic stress memory and mediates plasticity during acclimation to repeated sulfide stress in Urechis unicinctus
10.1016/j.jhazmat.2025.137264 · 2025 · External reference
Transcriptional memories mediate the plasticity of sulfide stress responses to enable acclimation in Urechis unicinctus
10.1016/j.ecoenv.2025.118020 · 2025 · External reference
Jumonji domain-containing 6 (JMJD6) identified as a potential therapeutic target in ovarian cancer
2019 · External reference
