Research graph
References from Persistent lymphopaenia in critically ill patients with and without sepsis: An Australian and New Zealand point prevalence study. Local targets link to admitted publications; unresolved targets remain external evidence.
The third international consensus definitions for sepsis and septic shock (Sepsis-3)
10.1001/jama.2016.0287 · 2016 · External reference
Global, regional, and national sepsis incidence and mortality, 1990–2021: a systematic analysis
10.1016/s2214-109x(25)00356-0 · 2025 · External reference
Unresolved reference
2025 · External reference
Increased 1-year healthcare use in survivors of severe sepsis
10.1164/rccm.201403-0471oc · 2014 · External reference
Evidence for persistent immune suppression in patients who develop chronic critical illness after sepsis
10.1097/shk.0000000000000981 · 2018 · External reference
Clinical impact of transient lymphopenia
10.1007/s10238-024-01340-0 · 2024 · External reference
Early persistent lymphopenia and risk of death in critically ill patients with and without sepsis
2023 · External reference
Persistent lymphopenia after diagnosis of sepsis predicts mortality
10.1097/shk.0000000000000234 · 2014 · External reference
Interleukin-7 restores lymphocytes in septic shock: the IRIS-7 randomized clinical trial
10.1172/jci.insight.98960 · 2018 · External reference
Lymphocyte subset responses to trauma and sepsis
10.1097/00005373-199312000-00007 · 1993 · External reference
Failure to normalize lymphopenia following trauma is associated with increased mortality, independent of the leukocytosis pattern
10.1186/cc11157 · 2012 · External reference
Successful treatment of progressive multifocal leukoencephalopathy with recombinant interleukin-7 and maraviroc in a patient with idiopathic CD4 lymphocytopenia
10.1007/s13365-018-0657-x · 2018 · External reference
Interleukin-7 unveils pathogen-specific T cells by enhancing antigen-recall responses
10.1093/infdis/jiy096 · 2018 · External reference
Immune checkpoint inhibitors for the treatment of sepsis: insights from preclinical and clinical development
10.1080/13543784.2022.2102477 · 2022 · External reference
A prospective analysis of lymphocyte phenotype and function over the course of acute sepsis
10.1186/cc11404 · 2012 · External reference
Immunosuppression in patients who die of sepsis and multiple organ failure
10.1001/jama.2011.1829 · 2011 · External reference
Defects in innate and adaptive immunity in patients with sepsis and health care associated infection
10.21037/atm.2017.09.21 · 2017 · External reference
Early changes in immune cell subsets with corticosteroids in patients with solid tumors: implications for COVID-19 management
10.1136/jitc-2020-001019 · 2020 · External reference
Unresolved reference
2016 · External reference
Research electronic data capture (REDCap)—a metadata-driven methodology and workflow process for providing translational research informatics support
10.1016/j.jbi.2008.08.010 · 2009 · External reference
The REDCap consortium: building an international community of software platform partners
10.1016/j.jbi.2019.103208 · 2019 · External reference
The APACHE III prognostic system. Risk prediction of hospital mortality for critically ill hospitalized adults
10.1378/chest.100.6.1619 · 1991 · External reference
The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine
10.1007/bf01709751 · 1996 · External reference
Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy
10.1038/nri3552 · 2013 · External reference
Predictive value of soluble programmed cell death ligand-1 in the progression of septic patients to chronic critical illness in the intensive care unit: a prospective observational clinical study
10.1097/shk.0000000000002156 · 2023 · External reference
Absolute lymphocyte count trajectory predicts clinical outcome in severely injured patients
10.1007/s00068-025-02864-0 · 2025 · External reference
Lymphopenia in sepsis: a narrative review
10.1186/s13054-024-05099-4 · 2024 · External reference
Severe lymphopenia is associated with elevated plasma Interleukin-15 levels and increased mortality during severe sepsis
10.1097/shk.0000000000000347 · 2015 · External reference
Admission lymphopenia predicts infectious complications and mortality in traumatic brain injury victims
10.1097/shk.0000000000001872 · 2022 · External reference
Nonviral infection-related lymphocytopenia for the prediction of adult sepsis and its persistence indicates a higher mortality
10.1097/md.0000000000016535 · 2019 · External reference
Accelerated lymphocyte death in sepsis occurs by both the death receptor and mitochondrial pathways
10.4049/jimmunol.174.8.5110 · 2005 · External reference
Intravenously administered interleukin-7 to reverse lymphopenia in patients with septic shock: a double-blind, randomized, placebo-controlled trial
10.1186/s13613-023-01109-w · 2023 · External reference
Treatable traits: toward precision medicine of chronic airway diseases
10.1183/13993003.01359-2015 · 2016 · External reference
Immunosuppression in Patients Who Die of Sepsis and Multiple Organ Failure
10.1001/jama.2011.1829 · 2011 · External reference
Immunosuppression in sepsis
10.1001/jama.2011.1831 · 2011 · External reference
