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References from Mechanisms of spatiotemporal regulation of transmembrane receptor turnover during directed cell migration. Local targets link to admitted publications; unresolved targets remain external evidence.
Abnormalities in chemokine receptor recycling in chronic lymphocytic leukemia
10.1007/s00018-019-03058-9 · 2019 · External reference
Spatial regulation of receptor tyrosine kinases in development and cancer
10.1038/nrc3277 · 2012 · External reference
GTP exchange factor Vav regulates guided cell migration by coupling guidance receptor signalling to local Rac activation
2013 · External reference
The landscape of GPCR signaling in the regulation of epidermal stem cell fate and skin homeostasis
10.1002/stem.3273 · 2020 · External reference
Chemokine receptor trafficking coordinates neutrophil clustering and dispersal at wounds in zebrafish
10.1038/s41467-019-13107-3 · 2019 · External reference
LRRK1 functions as a scaffold for PTP1B-mediated EGFR sorting into ILVs at the ER–endosome contact site
10.1242/jcs.260566 · 2023 · External reference
Endoplasmic reticulum–plasma membrane contact gradients direct cell migration
10.1038/s41586-024-07527-5 · 2024 · External reference
Integrins in cell migration
10.1101/cshperspect.a005074 · 2011 · External reference
Integrin trafficking in cells and tissues
10.1038/s41556-018-0223-z · 2019 · External reference
MT1-MMP-dependent cell migration: proteolytic and non-proteolytic mechanisms
10.1042/bst20180363 · 2019 · External reference
Cadherins in collective cell migration of mesenchymal cells
10.1016/j.ceb.2012.08.002 · 2012 · External reference
Binding kinetics of ligands acting at GPCRs
10.1016/j.mce.2019.01.018 · 2019 · External reference
Differential roles of kinetic on- and off-rates in T cell receptor signal integration revealed with a modified Fab’-DNA ligand
10.1073/pnas.2406680121 · 2024 · External reference
CXCL12 chemokine dimer signaling modulates acute myelogenous leukemia cell migration through altered receptor internalization
10.1038/s41598-025-12005-7 · 2025 · External reference
Migration of growth factor-stimulated epithelial and endothelial cells depends on EGFR transactivation by ADAM17
10.1038/ncomms1232 · 2011 · External reference
Dynamic buffering of extracellular chemokine by a dedicated scavenger pathway enables robust adaptation during directed tissue migration
10.1016/j.devcel.2020.01.013 · 2020 · External reference
Generation and dynamics of an endogenous, self-generated signaling gradient across a migrating tissue
10.1016/j.cell.2013.09.046 · 2013 · External reference
CXCR7 functions as a scavenger for CXCL12 and CXCL11
10.1371/journal.pone.0009175 · 2010 · External reference
Distinct compartmentalization of the chemokines CXCL1 and CXCL2 and the atypical receptor ACKR1 determine discrete stages of neutrophil diapedesis
10.1016/j.immuni.2018.09.018 · 2018 · External reference
CXCR7 prevents excessive CXCL12-mediated downregulation of CXCR4 in migrating cortical interneurons
10.1242/dev.104224 · 2014 · External reference
Heterologous regulation of CXCR4 lysosomal trafficking
10.1074/jbc.ra118.005991 · 2019 · External reference
Directional tissue migration through a self-generated chemokine gradient
10.1038/nature12635 · 2013 · External reference
The negative charge of the 343 site is essential for maintaining physiological functions of CXCR4
10.1186/s12860-021-00347-9 · 2021 · External reference
A chemotaxis model to explain WHIM neutrophil accumulation in the bone marrow of WHIM mouse model
10.1097/bs9.0000000000000019 · 2019 · External reference
Targeting the chemokine receptor CXCR4 for cancer therapies
10.1186/s40364-025-00778-y · 2025 · External reference
ArfGAP1 regulates the endosomal sorting of guidance receptors to promote directed collective cell migration in vivo
10.1016/j.isci.2023.107467 · 2023 · External reference
PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis
10.1038/ncomms13546 · 2016 · External reference
Directional persistence of migrating cells requires Kif1C-Mediated stabilization of trailing adhesions
10.1016/j.devcel.2012.11.005 · 2012 · External reference
Supracellular contraction at the rear of neural crest cell groups drives collective chemotaxis
10.1126/science.aau3301 · 2018 · External reference
Live-cell magnetic manipulation of recycling endosomes reveals their direct effect on actin protrusions to promote invasive migration
10.1126/sciadv.adu6361 · 2025 · External reference
N-cadherin dynamically regulates pediatric glioma cell migration in complex environments
10.1083/jcb.202401057 · 2024 · External reference
Spatial regulation of VEGF receptor endocytosis in angiogenesis
10.1038/ncb2679 · 2013 · External reference
Chemokine receptor distribution on the surface of repolarizing T cells
10.1016/j.bpj.2024.02.001 · 2024 · External reference
Vesicle trafficking pathways that direct cell migration in 3D matrices and in vivo
10.1111/tra.12605 · 2018 · External reference
Translation elongation rate varies among organs and decreases with age
10.1093/nar/gkaa1103 · 2021 · External reference
Folding of influenza hemagglutinin in the endoplasmic reticulum
10.1083/jcb.114.3.401 · 1991 · External reference
Kinetic analysis of secretory protein traffic and characterization of golgi to plasma membrane transport intermediates in living cells
10.1083/jcb.143.6.1485 · 1998 · External reference
Accurate measurement of fast endocytic recycling kinetics in real time
10.1242/jcs.231225 · 2020 · External reference
RAB6 and microtubules restrict protein secretion to focal adhesions
10.1083/jcb.201805002 · 2019 · External reference
Direct detection of guidance receptor activity during border cell migration
10.1073/pnas.0915075107 · 2010 · External reference
Guidance receptor promotes the asymmetric distribution of exocyst and recycling endosome during collective cell migration
10.1242/dev.094979 · 2013 · External reference
Spatial restriction of receptor tyrosine kinase activity through a polarized endocytic cycle controls border cell migration
10.1073/pnas.1010795108 · 2010 · External reference
Chemotaxis of Drosophila border cells is modulated by tissue geometry through dispersion of chemoattractants
10.1016/j.isci.2025.111959 · 2025 · External reference
Moving in the right direction: how eukaryotic cells migrate along chemical gradients
10.1016/j.semcdb.2011.07.020 · 2011 · External reference
Self-generated chemoattractant gradients: Attractant depletion extends the range and robustness of chemotaxis
10.1371/journal.pbio.1002404 · 2016 · External reference
GPCR-controlled membrane recruitment of negative regulator C2GAP1 locally inhibits Ras signaling for adaptation and long-range chemotaxis
10.1073/pnas.1703208114 · 2017 · External reference
Segregation of leading-edge and uropod components into specific lipid rafts during T cell polarization
10.1073/pnas.171160298 · 2001 · External reference
Ratiometric GPCR signaling enables directional sensing in yeast
10.1371/journal.pbio.3000484 · 2019 · External reference
The EGFR phosphatase RPTPγ is a redox-regulated suppressor of promigratory signaling
10.15252/embj.2022111806 · 2023 · External reference
Differential modes of regulation of CXC chemokine-induced internalization and recycling of human CXCR1 and CXCR2
10.1006/cyto.1999.0510 · 1999 · External reference
CCR7 acts as both a sensor and a sink for CCL19 to coordinate collective leukocyte migration
10.1126/sciimmunol.adc9584 · 2023 · External reference
A self-generated Toddler gradient guides mesodermal cell migration
10.1126/sciadv.add2488 · 2022 · External reference
Scavenging of soluble and immobilized CCL21 by ACKR4 regulates peripheral dendritic cell emigration
10.1073/pnas.2025763118 · 2021 · External reference
Zebrafish primordial germ cell migration
10.3389/fcell.2021.684460 · 2021 · External reference
Macrophages self-generate and refine chemotactic gradients during migration towards complement C5a
10.1371/journal.pbio.3003728 · 2026 · External reference
Regulation of cell dynamics by rapid integrin transport through the biosynthetic pathway
2025 · External reference
Interdependence between EGFR and phosphatases spatially established by vesicular dynamics generates a growth factor sensing and responding network
10.1016/j.cels.2018.06.006 · 2018 · External reference
Endocytosis drives active cAMP signal discrimination among natively co-expressed GPCRs
2025 · External reference
G protein–coupled receptor endocytosis generates spatiotemporal bias in β-arrestin signaling
10.1126/scisignal.adi0934 · 2024 · External reference
Chemokine receptor CCR7 triggers an endomembrane signaling complex for spatial rac activation
10.1016/j.celrep.2019.09.031 · 2019 · External reference
Intravesicular epidermal growth factor receptor subject to retrograde trafficking drives epidermal growth factor-dependent migration
10.18632/oncotarget.23766 · 2017 · External reference
Overexpression of wildtype EGFR is tumorigenic and denotes a therapeutic target in non-small cell lung cancer
10.18632/oncotarget.6461 · 2015 · External reference
Redundant roles of EGFR ligands in the ERK activation waves during collective cell migration
2021 · External reference
TimerQuant: a modelling approach to tandem fluorescent timer design and data interpretation for measuring protein turnover in embryos
2016 · External reference
Mobility measurement by analysis of fluorescence photobleaching recovery kinetics
10.1016/s0006-3495(76)85755-4 · 1976 · External reference
AMPA receptors exist in tunable Mobile and immobile synaptic fractions in vivo
10.1523/eneuro.0015-21.2021 · 2021 · External reference
Self-generated chemotaxis of mixed cell populations
10.1073/pnas.2504064122 · 2025 · External reference
Chemotaxing E. coli do not count single molecules
2025 · External reference
Emergent eukaryotic directional sensing via receptor degradation and diffusion
10.1073/pnas.2516077122 · 2025 · External reference
Quantitative visualization of endocytic trafficking through photoactivation of fluorescent proteins
10.1091/mbc.e20-10-0669 · 2021 · External reference
α5β1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3
10.1083/jcb.201502040 · 2015 · External reference
Macropinocytosis-mediated membrane recycling drives neural crest migration by delivering F-actin to the lamellipodium
10.1073/pnas.2007229117 · 2020 · External reference
Tracking and measuring local protein synthesis in vivo
10.1242/dev.202908 · 2024 · External reference
FRAP analysis measuring biophysical kinetic parameters using image analysis
2024 · External reference
Pcdh18a regulates endocytosis of E-cadherin during axial mesoderm development in zebrafish
10.1007/s00418-020-01887-5 · 2020 · External reference
In vivo study of gene expression with an enhanced dual-color fluorescent transcriptional timer
2019 · External reference
DELTA: a method for brain-wide measurement of synaptic protein turnover reveals localized plasticity during learning
10.1038/s41593-025-01923-4 · 2025 · External reference
Endosomal chemokine receptor signalosomes regulate central mechanisms underlying cell migration
10.7554/elife.99373.3 · 2025 · External reference
Ligand-dependent mechanisms of C-C chemokine receptor 5 (CCR5) trafficking revealed by APEX2 proximity labeling proteomics
2024 · External reference
Quantitative imaging of receptor-ligand engagement in intact live animals
10.1016/j.jconrel.2018.07.032 · 2018 · External reference
