Research graph
References from NEDD9 inhibits ox-LDL-induced endothelial anoikis to attenuate endothelial cell injury. Local targets link to admitted publications; unresolved targets remain external evidence.
Targeting mitochondrial function in macrophages: a novel treatment strategy for atherosclerotic cardiovascular disease?
10.1016/j.pharmthera.2023.108441 · 2023 · External reference
Atherosclerotic disease: pathogenesis and approaches to management
10.1016/j.mcna.2023.04.004 · 2023 · External reference
Cellular crosstalk in atherosclerotic plaque microenvironment
10.1186/s12964-023-01153-w · 2023 · External reference
Endothelial dysfunction in atherosclerotic cardiovascular diseases and beyond: from mechanism to pharmacotherapies
10.1124/pharmrev.120.000096 · 2021 · External reference
Different stimuli induce endothelial dysfunction and promote atherosclerosis through the Piezo1/YAP signaling axis
10.1016/j.abb.2023.109755 · 2023 · External reference
Biomarkers of endothelial activation and dysfunction in cardiovascular diseases
10.31083/j.rcm2302073 · 2022 · External reference
Endothelial cell dysfunction and the pathobiology of atherosclerosis
10.1161/circresaha.115.306301 · 2016 · External reference
Therapeutic potential of blood flow mimetic compounds in preventing endothelial dysfunction and atherosclerosis
10.1016/j.phrs.2020.104737 · 2020 · External reference
Anoikis: an emerging hallmark in health and diseases
10.1002/path.3000 · 2012 · External reference
Induction of tubulogenesis in telomerase-immortalized human microvascular endothelial cells by glioblastoma cells
10.1006/excr.2001.5424 · 2002 · External reference
Azilsartan ameliorates ox-LDL-induced endothelial dysfunction via promoting the expression of KLF2
10.18632/aging.202973 · 2021 · External reference
Role of ox-LDL and LOX-1 in atherogenesis
10.2174/0929867325666180508100950 · 2019 · External reference
LDL accelerates monocyte to macrophage differentiation: effects on adhesion and anoikis
10.1016/j.atherosclerosis.2016.01.002 · 2016 · External reference
Endothelial dysfunction drives CRTd outcome at 1-year follow-up: a novel role as biomarker for miR-130a-5p
10.3390/ijms24021510 · 2023 · External reference
Effects of metformin therapy on coronary endothelial dysfunction in patients with prediabetes with stable angina and nonobstructive coronary artery stenosis: the CODYCE multicenter prospective study
10.2337/dc18-2356 · 2019 · External reference
Could ghrelin expression regulate diastolic cardiac function in type 2 diabetic obese patients?
10.1002/dmrr.70049 · 2025 · External reference
Preclinical and clinical studies of the NEDD9 scaffold protein in cancer and other diseases
10.1016/j.gene.2015.04.086 · 2015 · External reference
NEDD9 is a novel and modifiable mediator of platelet-endothelial adhesion in the pulmonary circulation
10.1164/rccm.202003-0719oc · 2021 · External reference
Identification of genomic differences among peripheral arterial beds in atherosclerotic and healthy arteries
10.1038/s41598-018-22292-y · 2018 · External reference
Development of biomarker signatures associated with anoikis to predict prognosis in endometrial carcinoma patients
10.1155/2021/3375297 · 2021 · External reference
Inhibition of ferroptosis alleviates atherosclerosis through attenuating lipid peroxidation and endothelial dysfunction in mouse aortic endothelial cell
10.1016/j.freeradbiomed.2020.07.026 · 2020 · External reference
Oral ciprofloxacin therapy of infection caused by multiply resistant bacteria other than Pseudomonas aeruginosa
10.1093/jac/18.supplement_d.179 · 1986 · External reference
Loss of ADAMTS4 reduces high fat diet-induced atherosclerosis and enhances plaque stability in ApoE(−/−) mice
2016 · External reference
TCF7L2 promotes anoikis resistance and metastasis of gastric cancer by transcriptionally activating PLAUR
10.7150/ijbs.69933 · 2022 · External reference
Activation of Nrf2 inhibits atherosclerosis in ApoE(−/−) mice through suppressing endothelial cell inflammation and lipid peroxidation
10.1016/j.redox.2024.103229 · 2024 · External reference
Hydroxyurea ameliorates atherosclerosis in ApoE(−/−) mice by potentially modulating Niemann-pick C1-like 1 protein through the gut microbiota
10.7150/thno.76805 · 2022 · External reference
Extracellular matrix remodeling in tumor progression and immune escape: from mechanisms to treatments
10.1186/s12943-023-01744-8 · 2023 · External reference
Targeting TUBB3 suppresses anoikis resistance and bone metastasis in prostate cancer
2024 · External reference
Gefitinib induces anoikis in cervical cancer cells
10.5483/bmbrep.2023-0225 · 2024 · External reference
Integrated bulk and scRNA sequence identified anoikis-related diagnostic biomarkers and potential association with immune infiltration in type a aortic dissection
2023 · External reference
Novel anoikis-related diagnostic biomarkers for aortic dissection based on machine learning
2024 · External reference
HDL antielastase activity prevents smooth muscle cell anoikis, a potential new antiatherogenic property
10.1096/fj.08-127928 · 2009 · External reference
Identification of important genes related to anoikis in acute myocardial infarction
10.1111/jcmm.18264 · 2024 · External reference
Nedd9 restrains autophagy to limit growth of early stage non-small cell lung Cancer
10.1158/0008-5472.can-20-3626 · 2021 · External reference
NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migration
10.1371/journal.pone.0035058 · 2012 · External reference
Thrombospondin1 in tissue repair and fibrosis: TGF-β-dependent and independent mechanisms
10.1016/j.matbio.2012.01.006 · 2012 · External reference
Activation of mast cells by incorporation of cholesterol into rafts
10.1093/intimm/dxg120 · 2003 · External reference
DNA damage and repair in patients with coronary artery disease: correlation with plaque morphology using optical coherence tomography (DECODE study)
10.1016/j.carrev.2019.04.028 · 2019 · External reference
Polymorphism in ERCC1 confers susceptibility of coronary artery disease and severity of coronary artery atherosclerosis in a Chinese Han population
2017 · External reference
Nlrp3, Csf3, and Edn1 in macrophage response to saturated fatty acids and modified low-density lipoprotein
10.4070/kcj.2020.0117 · 2021 · External reference
Integrative pathway dissection of molecular mechanisms of moxLDL-induced vascular smooth muscle phenotype transformation
10.1186/1471-2261-13-4 · 2013 · External reference
C/EBPβ is a key transcription factor of ox-LDL inducing THP-1 cells to release multiple pro-inflammatory cytokines
10.1007/s00011-021-01509-3 · 2021 · External reference
Bicyclol alleviates atherosclerosis by manipulating gut microbiota
2022 · External reference
Early intermittent hyperlipidaemia alters tissue macrophages to fuel atherosclerosis
10.1038/s41586-024-07993-x · 2024 · External reference
Paternal hypercholesterolemia elicits sex-specific exacerbation of atherosclerosis in offspring
10.1172/jci.insight.179291 · 2024 · External reference
The role of gut microbiome and its interaction with arsenic exposure in carotid intima-media thickness in a Bangladesh population
10.1016/j.envint.2018.11.049 · 2019 · External reference
Pulmonary endothelial NEDD9 and the prothrombotic pathophenotype of acute respiratory distress syndrome due to SARS-CoV-2 infection
10.1002/pul2.12071 · 2022 · External reference
NEDD9 mediates the FAK/Src Signaling pathway to promote the adhesion of human trabecular meshwork cells after dexamethasone treatment
10.1080/02713683.2022.2071945 · 2022 · External reference
Molecular basis for HEF1/NEDD9/Cas-L action as a multifunctional co-ordinator of invasion, apoptosis and cell cycle
10.1007/s12013-007-0036-3 · 2007 · External reference
The prognostic significance of NEDD9 expression in human cancers: a systematic review, meta-analysis, and omics exploration
10.1177/15330338241297597 · 2024 · External reference
EIF4A3 promotes muscle atrophy and aging by inhibiting the FAK pathway through NEDD9 mRNA destabilization
10.1002/jcsm.70010 · 2025 · External reference
Transcription factor 7 like 2 promotes metastasis in hepatocellular carcinoma via NEDD9-mediated activation of AKT/mTOR signaling pathway
10.1186/s10020-024-00878-9 · 2024 · External reference
NEDD9 is transcriptionally regulated by HDAC4 and promotes breast cancer metastasis and macrophage M2 polarization via the FAK/NF-κB signaling pathway
10.1016/j.neo.2024.101059 · 2024 · External reference
Hepatocyte growth factor facilitates the repair of spinal cord injuries by driving the chemotactic migration of mesenchymal stem cells through the β-catenin/TCF4/Nedd9 signaling pathway
10.1093/stmcls/sxae055 · 2024 · External reference
