Research graph
References from CircENO1 drives gastric cancer progression via SPI1-mediated transcriptional activation of ENO1. Local targets link to admitted publications; unresolved targets remain external evidence.
The current landscape of gastric cancer and gastroesophageal junction cancer diagnosis and treatment in China: a comprehensive nationwide cohort analysis
10.1186/s13045-025-01698-y · 2025 · External reference
Anti-cancer bioactive peptide induces apoptosis in gastric cancer cells through TP53 signaling Cascade
10.2174/0109298665350654250111144722 · 2025 · External reference
Exploring the pharmacological mechanisms of P-hydroxylcinnamaldehyde for treating gastric cancer: a pharmacological perspective with experimental confirmation
10.2174/0118761429322420241112051105 · 2024 · External reference
FAT4 mutation is related to tumor mutation burden and favorable prognosis in gastric cancer
10.2174/0113892029300694240612081006 · 2024 · External reference
The CXCL12-CXCR4 Signaling Axis plays a key role in cancer metastasis and is a potential target for developing novel therapeutics against metastatic cancer
10.2174/0929867326666191113113110 · 2020 · External reference
Crosstalk between cancer-associated fibroblasts and myeloid cells shapes the heterogeneous microenvironment of gastric cancer
10.2174/0113892029300608240531111743 · 2024 · External reference
Gastric cancer: a review
10.1001/jama.2025.20034 · 2026 · External reference
H3K18 lactylation-mediated VCAM1 expression promotes gastric cancer progression and metastasis via AKT-mTOR-CXCL1 axis
10.1016/j.bcp.2024.116120 · 2024 · External reference
Long-chain non-coding RNA LINC01554 promotes NGFR expression and inhibits cell proliferation, migration, and invasion in hepatocellular carcinoma by binding to microRNA-3681-3p
2020 · External reference
MicroRNA-216b regulates cell proliferation, invasion and cycle progression via interaction with cyclin T2 in gastric cancer
10.1097/cad.0000000000000915 · 2020 · External reference
Circular RNA EIF4G3 suppresses gastric cancer progression through inhibition of β-catenin by promoting δ-catenin ubiquitin degradation and upregulating SIK1
10.1186/s12943-022-01606-9 · 2022 · External reference
Functional properties of circular RNAs and research progress in gastric cancer
10.3389/fonc.2022.954637 · 2022 · External reference
A novel circRNA, hsa_circ_0069382, regulates gastric cancer progression
10.1186/s12935-023-02871-4 · 2023 · External reference
The circular RNA circDLG1 promotes gastric cancer progression and anti-PD-1 resistance through the regulation of CXCL12 by sponging miR-141-3p
10.1186/s12943-021-01475-8 · 2021 · External reference
The emerging role of the interactions between circular RNAs and RNA-binding proteins in common human cancers
10.7150/jca.58182 · 2021 · External reference
Understanding the roles and regulation patterns of circRNA on its host gene in tumorigenesis and tumor progression
10.1186/s13046-023-02657-6 · 2023 · External reference
Circular RNA: from non-coding regulators to functional protein encoders
10.1016/j.pscia.2025.100085 · 2025 · External reference
CircRNA-ENO1 promoted glycolysis and tumor progression in lung adenocarcinoma through upregulating its host gene ENO1
10.1038/s41419-019-2127-7 · 2019 · External reference
Myeloid cell-specific mutation of Spi1 selectively reduces M2-biased macrophage numbers in skeletal muscle, reduces age-related muscle fibrosis and prevents sarcopenia
10.1111/acel.13690 · 2022 · External reference
SPI1-induced downregulation of FTO promotes GBM progression by regulating pri-miR-10a processing in an m6A-dependent manner
10.1016/j.omtn.2021.12.035 · 2022 · External reference
SPI1 is a prognostic biomarker of immune infiltration and immunotherapy efficacy in clear cell renal cell carcinoma
10.1007/s12672-022-00592-0 · 2022 · External reference
Study on the role of transcription factor SPI1 in the development of glioma
10.1186/s41016-022-00276-2 · 2022 · External reference
Low expression of LncRNA-CAF attributed to the high expression of HIF1A in esophageal squamous cell carcinoma and gastric cancer patients
10.1007/s11033-021-06882-0 · 2022 · External reference
Expression of AKRs superfamily and prognostic in human gastric cancer
10.1097/md.0000000000033041 · 2023 · External reference
Spi-1 proto-oncogene regulates mRNA hypertranscription and malignant progression in head and neck cancer
2026 · External reference
SPI1 activates TGF-β1/PI3K/Akt signaling through transcriptional upregulation of FKBP12 to support the mesenchymal phenotype of glioma stem cells
10.1111/bpa.13217 · 2024 · External reference
circ3323 motivates host gene to promote the aggressiveness of bladder cancer
10.1007/s10528-022-10210-x · 2022 · External reference
Epithelial-mesenchymal transition-related circular RNAs in lung carcinoma
10.20892/j.issn.2095-3941.2020.0238 · 2021 · External reference
Circular RNAs regulate glucose metabolism in cancer cells
10.2147/ott.s316597 · 2021 · External reference
CCDC65 as a new potential tumor suppressor induced by metformin inhibits activation of AKT1 via ubiquitination of ENO1 in gastric cancer
10.7150/thno.54961 · 2021 · External reference
Salidroside induces apoptosis in human gastric cancer cells via the downregulation of ENO1/PKM2/GLUT1 expression
10.1248/bpb.b21-00443 · 2021 · External reference
KMT5A downregulation participated in high glucose-mediated EndMT via upregulation of ENO1 expression in diabetic nephropathy
10.7150/ijbs.62867 · 2021 · External reference
Alcohol consumption and risks of more than 200 diseases in Chinese men
10.1038/s41591-023-02383-8 · 2023 · External reference
Hyperglycemia promotes snail-induced epithelial-mesenchymal transition of gastric cancer via activating ENO1 expression
10.1186/s12935-019-1075-8 · 2019 · External reference
Ciwujianoside E inhibits Burkitt lymphoma cell proliferation and invasion by blocking ENO1-plasminogen interaction and TGF-β1 activation
10.1016/j.biopha.2024.116970 · 2024 · External reference
The significance of glycolysis in tumor progression and its relationship with the tumor microenvironment
10.3389/fphar.2022.1091779 · 2022 · External reference
The epithelial–mesenchymal transition at the crossroads between metabolism and tumor progression
10.3390/ijms23020800 · 2022 · External reference
Doxazosin attenuates development of testosterone propionate-induced prostate growth by regulating TGF-β/Smad signaling pathway, prostate-specific antigen expression and reversing epithelial-mesenchymal transition in mice and stroma cells
2025 · External reference
Metabolic regulation of epithelial to mesenchymal transition: implications for endocrine cancer
10.3389/fendo.2019.00773 · 2019 · External reference
SPI1 mediates N-myristoyltransferase 1 to advance gastric cancer progression via PI3K/AKT/mTOR pathway
10.1155/2023/2021515 · 2023 · External reference
Comprehensive analysis of immune implications and prognostic value of SPI1 in gastric cancer
2022 · External reference
EIF4A3 induced circABCA5 promotes the gastric cancer progression by SPI1 mediated IL6/JAK2/STAT3 signaling
2023 · External reference
Long noncoding RNA NR2F1-AS1 plays a carcinogenic role in gastric cancer by recruiting transcriptional factor SPI1 to upregulate ST8SIA1 expression
10.1080/21655979.2021.2001168 · 2021 · External reference
CBP/p300 and HDAC activities regulate H3K27 acetylation dynamics and zygotic genome activation in mouse preimplantation embryos
10.15252/embj.2022112012 · 2022 · External reference
Histone-modifying enzymes as drivers and therapeutic targets in androgen-resistant prostate cancer
2025 · External reference
