Research graph
References from CYTIP promotes pro-inflammatory activation of microglia through interaction with LRRFIP2 following ischemic stroke. Local targets link to admitted publications; unresolved targets remain external evidence.
Burden of ischemic and hemorrhagic stroke across the US from 1990 to 2019
10.1001/jamaneurol.2024.0190 · 2024 · External reference
10.1016/s1474-4422(21)00252-0
10.1016/s1474-4422(21)00252-0 · 2021 · External reference
Alteplase or tenecteplase for thrombolysis in ischemic stroke: an illustrated review
10.1002/rth2.12795 · 2022 · External reference
Trial of thrombectomy for stroke with a large infarct of unrestricted size
10.1056/nejmoa2314063 · 2024 · External reference
Global burden, risk factor analysis, and prediction study of ischemic stroke, 1990-2030
10.1212/wnl.0000000000207387 · 2023 · External reference
Global burden of ischemic stroke in young adults in 204 countries and territories
10.1212/wnl.0000000000201467 · 2023 · External reference
Dynamic mechanisms and targeted interventions in cerebral ischemia-reperfusion injury: pathological cascade from ischemia to reperfusion and promising therapeutic strategies
10.3389/fnins.2025.1649533 · 2025 · External reference
Ischemia and reperfusion—from mechanism to translation
10.1038/nm.2507 · 2011 · External reference
The effect of cinnamon bark oil in bilateral common carotid artery occlusion-induced cerebral ıischemia model in rats
10.1038/s41598-025-23284-5 · 2025 · External reference
Immunological mechanisms and therapeutic strategies in cerebral ischemia-reperfusion injury: from inflammatory response to neurorepair
10.3390/ijms26178336 · 2025 · External reference
Microglia function in the central nervous system during health and neurodegeneration
10.1146/annurev-immunol-051116-052358 · 2017 · External reference
Unresolved reference
2025 · External reference
The dual function of microglial polarization and its treatment targets in ischemic stroke
10.3389/fneur.2022.921705 · 2022 · External reference
Microglial polarization and therapeutic strategies in post-stroke neuroinflammation
10.1007/s40120-025-00825-8 · 2025 · External reference
Neuroinflammation in cerebral ischemia and ischemia/reperfusion injuries: from pathophysiology to therapeutic strategies
10.3390/ijms23010014 · 2021 · External reference
Microglia autophagy in ischemic stroke: a double-edged sword
10.3389/fimmu.2022.1013311 · 2022 · External reference
Microglial autophagy and mitophagy in ischemic stroke: from dual roles to therapeutic modulation
10.3390/biology14091269 · 2025 · External reference
The role of microglial phagocytosis in ischemic stroke
2021 · External reference
The antioxidant enzyme Peroxiredoxin-1 controls stroke-associated microglia against acute ischemic stroke
10.1016/j.redox.2022.102347 · 2022 · External reference
Novel CH25H(+) and OASL(+) microglia subclusters play distinct roles in cerebral ischemic stroke
10.1186/s12974-023-02799-6 · 2023 · External reference
Microglial heterogeneity in the ischemic stroke mouse brain of both sexes
10.1186/s13073-024-01368-7 · 2024 · External reference
Microglial polarization: novel therapeutic strategy against ischemic stroke
10.14336/ad.2020.0701 · 2021 · External reference
Macrophage polarization in physiological and pathological pregnancy
10.3389/fimmu.2019.00792 · 2019 · External reference
Targeting microglial activation states as a therapeutic avenue in Parkinson's disease
10.3389/fnagi.2017.00176 · 2017 · External reference
Management of the brain: essential oils as promising neuroinflammation modulator in neurodegenerative diseases
10.3390/antiox13020178 · 2024 · External reference
Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia
10.1161/strokeaha.112.659656 · 2012 · External reference
Analysis of IL-4/STAT6 signaling in macrophages
10.1007/978-1-4939-9195-2_17 · 2019 · External reference
cAMP levels regulate macrophage alternative activation marker expression
10.1177/1753425920975082 · 2021 · External reference
Macrophage reprogramming and cancer therapeutics: role of iNOS-derived NO
10.3390/cells10113194 · 2021 · External reference
Small-sample learning reveals propionylation in determining global protein homeostasis
10.1038/s41467-023-38414-8 · 2023 · External reference
Monitoring of single-nucleus chromatin landscape of ischemic stroke in mouse cerebral cortex across time
10.1038/s41597-025-04367-4 · 2025 · External reference
Comparison and evaluation of statistical error models for scRNA-seq
10.1186/s13059-021-02584-9 · 2022 · External reference
Fast, sensitive and accurate integration of single-cell data with Harmony
10.1038/s41592-019-0619-0 · 2019 · External reference
Integrated analysis of multimodal single-cell data
10.1016/j.cell.2021.04.048 · 2021 · External reference
A unique microglia type associated with restricting development of Alzheimer's disease
10.1016/j.cell.2017.05.018 · 2017 · External reference
White matter microglia heterogeneity in the CNS
10.1007/s00401-021-02389-x · 2022 · External reference
Single-cell sequencing and transcriptomic data reveal that P65 activation significantly promotes microglia-mediated neuroinflammation after ischemic stroke
10.1038/s41598-025-00524-2 · 2025 · External reference
Current methodological challenges of single-cell and single-nucleus RNA-sequencing in glomerular diseases
10.1681/asn.2021020157 · 2021 · External reference
Eleven grand challenges in single-cell data science
10.1186/s13059-020-1926-6 · 2020 · External reference
sVCAM1 in the hippocampus contributes to postoperative cognitive dysfunction in mice by inducing microglial activation through the VLA-4 receptor
10.1007/s12035-022-02924-1 · 2022 · External reference
The role of VCAM1 in post-stroke cognitive impairment: molecular mechanisms and therapeutic potential
10.1016/j.brainresbull.2025.111584 · 2025 · External reference
Multiple synergistic anti-aging effects of vascular cell adhesion molecule 1 functionalized nanoplatform to improve age-related neurodegenerative diseases
10.1016/j.jconrel.2025.01.022 · 2025 · External reference
LRRFIP2 negatively regulates NLRP3 inflammasome activation in macrophages by promoting Flightless-I-mediated caspase-1 inhibition
10.1038/ncomms3075 · 2013 · External reference
