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References from NUP35 drives the Warburg effect and malignant progression in glioblastoma by regulating GCKR stability and HK2 activation. Local targets link to admitted publications; unresolved targets remain external evidence.
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
10.1056/nejmoa043330 · 2005 · External reference
Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions
10.1093/neuonc/noaa106 · 2020 · External reference
Pediatric high-grade glioma: biologically and clinically in need of new thinking
2017 · External reference
10.1158/2159-8290.cd-21-1094
10.1158/2159-8290.cd-21-1094 · External reference
Clinical practice guidelines for the management of adult diffuse gliomas
10.1016/j.canlet.2020.10.050 · 2021 · External reference
Understanding high grade glioma: molecular mechanism, therapy and comprehensive management
10.1016/j.canlet.2012.12.024 · 2013 · External reference
Tumor glycolysis, an essential sweet tooth of tumor cells
10.1016/j.semcancer.2022.09.007 · 2022 · External reference
The suitability of glioblastoma cell lines as models for primary glioblastoma cell metabolism
10.3390/cancers12123722 · 2020 · External reference
The molecular architecture of the nuclear basket
10.1016/j.cell.2024.07.020 · 2024 · External reference
Mechanistic insights and potential therapeutic approaches for NUP98-rearranged hematologic malignancies
10.1182/blood.2020007093 · 2020 · External reference
Nup210 promotes colorectal cancer progression by regulating nuclear plasma transport
10.1016/j.labinv.2024.102149 · 2024 · External reference
Bioinformatics analysis of the expression and clinical significance of the NUP210 gene in acute myeloid leukaemia
10.1080/16078454.2022.2061107 · 2022 · External reference
Nucleoporin35 is a novel microtubule associated protein functioning in oocyte meiotic spindle architecture
10.1016/j.yexcr.2018.09.004 · 2018 · External reference
The crystal structure of mouse Nup35 reveals atypical RNP motifs and novel homodimerization of the RRM domain [J]
10.1016/j.jmb.2006.07.089 · 2006 · External reference
Proteolytic regulation of metabolic enzymes by E3 ubiquitin ligase complexes: lessons from yeast
10.3109/10409238.2015.1081869 · 2015 · External reference
The MAP3K13-TRIM25-FBXW7α axis affects c-Myc protein stability and tumor development
10.1038/s41418-019-0363-0 · 2020 · External reference
Cycloheximide (CHX) chase assay to examine protein half-life
10.21769/bioprotoc.4690 · 2023 · External reference
Analysis of protein stability by the cycloheximide chase assay
10.21769/bioprotoc.1374 · 2015 · External reference
Glioblastoma at the crossroads: current understanding and future therapeutic horizons
10.1038/s41392-025-02299-4 · 2025 · External reference
The nuclear pore complex and the genome: organizing and regulatory principles
10.1016/j.gde.2021.01.005 · 2021 · External reference
Ahctf1 and kras mutations combine to amplify oncogenic stress and restrict liver overgrowth in a zebrafish model of hepatocellular carcinoma
10.7554/elife.73407 · 2023 · External reference
The HK2 dependent "Warburg effect" and mitochondrial oxidative phosphorylation in cancer: targets for effective therapy with 3-bromopyruvate
10.3390/molecules21121730 · 2016 · External reference
Ubiquitination and deubiquitination in cancer: from mechanisms to novel therapeutic approaches
10.1186/s12943-024-02046-3 · 2024 · External reference
The role of TRIM25 in the occurrence and development of cancers and inflammatory diseases
10.1016/j.bbcan.2023.188954 · 2023 · External reference
Suppression of ITPKB degradation by Trim25 confers TMZ resistance in glioblastoma through ROS homeostasis
10.1038/s41392-024-01763-x · 2024 · External reference