Research graph
References from Mycn facilitates hematopoietic stem and progenitor cell generation from endothelial cells by inhibiting adhesion signaling. Local targets link to admitted publications; unresolved targets remain external evidence.
In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium
10.1038/nature08764 · 2010 · External reference
Blood Development: Hematopoietic Stem Cell Dependence and Independence
10.1016/j.stem.2018.04.015 · 2018 · External reference
Definitive hematopoiesis is autonomously initiated by the AGM region
10.1016/s0092-8674(00)80165-8 · 1996 · External reference
Hematopoietic stem cells localize to the endothelial cell layer in the midgestation mouse aorta
10.1016/s1074-7613(02)00313-8 · 2002 · External reference
Of lineage and legacy: the development of mammalian hematopoietic stem cells
10.1038/ni1560 · 2008 · External reference
Haematopoietic stem cells derive directly from aortic endothelium during development
10.1038/nature08738 · 2010 · External reference
Inflammatory signaling regulates embryonic hematopoietic stem and progenitor cell production
10.1101/gad.253302.114 · 2014 · External reference
Interleukin-6 signaling regulates hematopoietic stem cell emergence
10.1038/s12276-019-0320-5 · 2019 · External reference
HIF1α-induced PDGFRβ signaling promotes developmental HSC production via IL-6 activation
10.1016/j.exphem.2016.10.002 · 2017 · External reference
Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production
10.1016/j.devcel.2020.07.015 · 2020 · External reference
Inflammatory signals directly instruct PU.1 in HSCs via TNF
10.1182/blood-2018-02-832998 · 2019 · External reference
Hematopoietic stem cell fate is established by the Notch-Runx pathway
10.1101/gad.1337005 · 2005 · External reference
Transforming Growth Factor β Drives Hemogenic Endothelium Programming and the Transition to Hematopoietic Stem Cells
10.1016/j.devcel.2016.06.024 · 2016 · External reference
Hematopoietic stem cell development requires transient Wnt/β-catenin activity
10.1084/jem.20120225 · 2012 · External reference
Mathematical model of a gene regulatory network reconciles effects of genetic perturbations on hematopoietic stem cell emergence
10.1016/j.ydbio.2013.04.016 · 2013 · External reference
A somitic Wnt16/Notch pathway specifies haematopoietic stem cells
10.1038/nature10107 · 2011 · External reference
Runx1-mediated hematopoietic stem-cell emergence is controlled by a Gata/Ets/SCL-regulated enhancer
10.1182/blood-2007-07-100883 · 2007 · External reference
Functional and molecular characterization of mouse Gata2-independent hematopoietic progenitors
10.1182/blood-2015-10-673749 · 2016 · External reference
Meis1 establishes the pre-hemogenic endothelial state prior to Runx1 expression
10.1038/s41467-023-40283-0 · 2023 · External reference
Combined Single-Cell Profiling of lncRNAs and Functional Screening Reveals that H19 Is Pivotal for Embryonic Hematopoietic Stem Cell Development
10.1016/j.stem.2018.11.023 · 2019 · External reference
Pre-configuring chromatin architecture with histone modifications guides hematopoietic stem cell formation in mouse embryos
10.1038/s41467-022-28018-z · 2022 · External reference
Single-cell architecture and functional requirement of alternative splicing during hematopoietic stem cell formation
2022 · External reference
Developmental trajectory of prehematopoietic stem cell formation from endothelium
10.1182/blood.2020004801 · 2020 · External reference
Tracing haematopoietic stem cell formation at single-cell resolution
10.1038/nature17997 · 2016 · External reference
Single-cell transcriptomics reveal the dynamic of haematopoietic stem cell production in the aorta
10.1038/s41467-018-04893-3 · 2018 · External reference
Embryonic endothelial evolution towards first hematopoietic stem cells revealed by single-cell transcriptomic and functional analyses
10.1038/s41422-020-0300-2 · 2020 · External reference
Murine AGM single-cell profiling identifies a continuum of hemogenic endothelium differentiation marked by ACE
10.1182/blood.2020007885 · 2022 · External reference
Deciphering the continuum of hemogenic endothelium differentiation
10.1182/blood.2021013853 · 2022 · External reference
New insights into the endothelial origin of hematopoietic system inspired by “TIF” approaches
10.1097/bs9.0000000000000199 · 2024 · External reference
Single-cell transcriptomic dissection of two waves of endothelial-hematopoietic transition in a murine yolk sac
10.1097/bs9.0000000000000260 · 2025 · External reference
When blood development meets single-cell transcriptomics
10.1097/bs9.0000000000000007 · 2019 · External reference
Ribosome biogenesis is essential for hemogenic endothelial cells to generate hematopoietic stem cells
10.1242/dev.202875 · 2024 · External reference
Analysis of endothelial-to-haematopoietic transition at the single cell level identifies cell cycle regulation as a driver of differentiation
10.1186/s13059-020-02058-4 · 2020 · External reference
Single-cell profiling reveals three endothelial-to-hematopoietic transitions with divergent isoform expression landscapes
10.1038/s44161-025-00740-z · 2025 · External reference
Divergent expression of Neurl3 from hemogenic endothelial cells to hematopoietic stem progenitor cells during development
10.1016/j.jgg.2023.05.006 · 2023 · External reference
Hlf Expression Marks Early Emergence of Hematopoietic Stem Cell Precursors With Adult Repopulating Potential and Fate
10.3389/fcell.2021.728057 · 2021 · External reference
Nupr1 Negatively Regulates Endothelial to Hematopoietic Transition in the Aorta-Gonad-Mesonephros Region
2023 · External reference
MYCN oncoprotein targets and their therapeutic potential
10.1016/j.canlet.2010.01.015 · 2010 · External reference
Target gene-independent functions of MYC oncoproteins
10.1038/s41580-020-0215-2 · 2020 · External reference
Transposition and amplification of oncogene-related sequences in human neuroblastomas
10.1016/0092-8674(83)90169-1 · 1983 · External reference
Targeting MYCN in Pediatric and Adult Cancers
2020 · External reference
The Expanding World of N-MYC-Driven Tumors
10.1158/2159-8290.cd-17-0273 · 2018 · External reference
Neuroblastoma and MYCN
10.1101/cshperspect.a014415 · 2013 · External reference
MYCN, neuroblastoma and focal adhesion kinase (FAK)
10.2741/e257 · 2011 · External reference
A Review of the Regulatory Mechanisms of N-Myc on Cell Cycle
10.3390/molecules28031141 · 2023 · External reference
MYC: connecting selective transcriptional control to global RNA production
10.1038/nrc3984 · 2015 · External reference
Complementation of Myc-dependent cell proliferation by cDNA expression library screening
10.1038/sj.onc.1203880 · 2000 · External reference
c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation
10.1101/gad.313104 · 2004 · External reference
Hematopoietic Stem Cell Function and Survival Depend on c-Myc and N-Myc Activity
10.1016/j.stem.2008.09.005 · 2008 · External reference
c-myc in the hematopoietic lineage is crucial for its angiogenic function in the mouse embryo
10.1242/dev.020131 · 2008 · External reference
Adult-repopulating lymphoid potential of yolk sac blood vessels is not confined to arterial endothelial cells
10.1007/s11427-021-1935-2 · 2021 · External reference
The (intra-aortic) hematopoietic cluster cocktail: what is in the mix?
10.1016/j.exphem.2022.12.002 · 2023 · External reference
The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system
10.1038/nature03080 · 2004 · External reference
Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification
10.1038/s41467-017-01742-7 · 2017 · External reference
Heterogeneity in endothelial cells and widespread venous arterialization during early vascular development in mammals
10.1038/s41422-022-00615-z · 2022 · External reference
Mapping human haematopoietic stem cells from haemogenic endothelium to birth
10.1038/s41586-022-04571-x · 2022 · External reference
N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation
10.1101/gad.1021202 · 2002 · External reference
Spatiotemporal and Functional Heterogeneity of Hematopoietic Stem Cell-Competent Hemogenic Endothelial Cells in Mouse Embryos
2021 · External reference
Heterogeneity of high-potency multilineage hematopoietic stem cells and identification of “Super” transplantability
10.1182/blood.2024027872 · 2025 · External reference
N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis
10.1093/emboj/20.6.1383 · 2001 · External reference
MYCN drives oncogenesis by cooperating with the histone methyltransferase G9a and the WDR5 adaptor to orchestrate global gene transcription
10.1371/journal.pbio.3002240 · 2024 · External reference
MYCN and KAT2A form a feedforward loop to drive an oncogenic transcriptional program in neuroblastoma
10.1038/s41389-025-00557-2 · 2025 · External reference
N-MYC DOWN REGULATES NEURAL CELL-ADHESION MOLECULE EXPRESSION IN RAT NEUROBLASTOMA
1990 · External reference
Over-expression of transfected N-myc oncogene in human SKNSH neuroblastoma cells down-regulates expression of beta 1 integrin subunit
1995 · External reference
N-myc over-expression downregulates alpha3beta1 integrin expression in human Saos-2 osteosarcoma cells
10.1023/a:1018417330479 · 1997 · External reference
Focal Adhesion Kinase (FAK) and c-Src Dependent Signal Transduction in Cell Adhesion
10.24976/discov.med.202436189.184 · 2024 · External reference
VE-Cadherin modulates β-catenin/TCF-4 to enhance Vasculogenic Mimicry
10.1038/s41419-023-05666-7 · 2023 · External reference
A Small Molecule Inhibitor, 1,2,4,5-Benzenetetraamine Tetrahydrochloride, Targeting the Y397 Site of Focal Adhesion Kinase Decreases Tumor Growth
10.1021/jm800483v · 2008 · External reference
A novel small molecule inhibitor of FAK decreases growth of human pancreatic cancer
10.4161/cc.8.15.9145 · 2009 · External reference
Focal Adhesion Remodeling Is Crucial for Glucose-Stimulated Insulin Secretion and Involves Activation of Focal Adhesion Kinase and Paxillin
10.2337/db10-0946 · 2011 · External reference
Inhibition of cell migration by focal adhesion kinase: Time-dependent difference in integrin-induced signaling between endothelial and hepatoblastoma cells
2018 · External reference
Programming multicellular assembly with synthetic cell adhesion molecules
10.1038/s41586-022-05622-z · 2023 · External reference
Activation of the TGFβ pathway impairs endothelial to haematopoietic transition
10.1038/srep21518 · 2016 · External reference
Tuning apicobasal polarity and junctional recycling in the hemogenic endothelium orchestrates the morphodynamic complexity of emerging pre-hematopoietic stem cells
10.7554/elife.91429 · 2024 · External reference
RUNX1 positively regulates a cell adhesion and migration program in murine hemogenic endothelium prior to blood emergence
10.1182/blood-2014-04-572958 · 2014 · External reference
Let-7 microRNA-dependent control of leukotriene signaling regulates the transition of hematopoietic niche in mice
10.1038/s41467-017-00137-y · 2017 · External reference
Tracing the first hematopoietic stem cell generation in human embryo by single-cell RNA sequencing
10.1038/s41422-019-0228-6 · 2019 · External reference
TopHat: discovering splice junctions with RNA-Seq
10.1093/bioinformatics/btp120 · 2009 · External reference
BEDTools: a flexible suite of utilities for comparing genomic features
10.1093/bioinformatics/btq033 · 2010 · External reference
Twelve years of SAMtools and BCFtools
10.1093/gigascience/giab008 · 2021 · External reference
deepTools2: a next generation web server for deep-sequencing data analysis
10.1093/nar/gkw257 · 2016 · External reference
Integrative genomics viewer
10.1038/nbt.1754 · 2011 · External reference
Integrated analysis of multimodal single-cell data
10.1016/j.cell.2021.04.048 · 2021 · External reference
DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors
10.1016/j.cels.2019.03.003 · 2019 · External reference
Reversed graph embedding resolves complex single-cell trajectories
10.1038/nmeth.4402 · 2017 · External reference
clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters
10.1089/omi.2011.0118 · 2012 · External reference
hdWGCNA identifies co-expression networks in high-dimensional transcriptomics data
2023 · External reference
ANGPTL2-containing small extracellular vesicles from vascular endothelial cells accelerate leukemia progression
10.1172/jci138986 · 2021 · External reference
Hierarchical organization and early hematopoietic specification of the developing HSC lineage in the AGM region
10.1084/jem.20102419 · 2011 · External reference
Mouse Embryonic Head as a Site for Hematopoietic Stem Cell Development
10.1016/j.stem.2012.07.004 · 2012 · External reference
ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
10.1016/j.jim.2009.06.008 · 2009 · External reference
Tracing the temporal-spatial transcriptome landscapes of the human fetal digestive tract using single-cell RNA-sequencing
10.1038/s41556-018-0105-4 · 2018 · External reference
Choice of pre-processing pipeline influences clustering quality of scRNA-seq datasets
10.1186/s12864-021-07930-6 · 2021 · External reference
Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets
10.1016/j.cell.2015.05.002 · 2015 · External reference
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
10.1126/science.aad0501 · 2016 · External reference
Adult-repopulating lymphoid potential of yolk sac blood vessels is not confined to arterial endothelial cells
10.1007/s11427-021-1935-2 · ExternalCitation · doi-reference
Transposition and amplification of oncogene-related sequences in human neuroblastomas
10.1016/0092-8674(83)90169-1 · ExternalCitation · doi-reference
MYCN oncoprotein targets and their therapeutic potential
10.1016/j.canlet.2010.01.015 · ExternalCitation · doi-reference
Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets
10.1016/j.cell.2015.05.002 · ExternalCitation · doi-reference
Integrated analysis of multimodal single-cell data
10.1016/j.cell.2021.04.048 · ExternalCitation · doi-reference
DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors
10.1016/j.cels.2019.03.003 · ExternalCitation · doi-reference
Transforming Growth Factor β Drives Hemogenic Endothelium Programming and the Transition to Hematopoietic Stem Cells
10.1016/j.devcel.2016.06.024 · ExternalCitation · doi-reference
Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production
10.1016/j.devcel.2020.07.015 · ExternalCitation · doi-reference
HIF1α-induced PDGFRβ signaling promotes developmental HSC production via IL-6 activation
10.1016/j.exphem.2016.10.002 · ExternalCitation · doi-reference
The (intra-aortic) hematopoietic cluster cocktail: what is in the mix?
10.1016/j.exphem.2022.12.002 · ExternalCitation · doi-reference
Divergent expression of Neurl3 from hemogenic endothelial cells to hematopoietic stem progenitor cells during development
10.1016/j.jgg.2023.05.006 · ExternalCitation · doi-reference
ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
10.1016/j.jim.2009.06.008 · ExternalCitation · doi-reference
Hematopoietic Stem Cell Function and Survival Depend on c-Myc and N-Myc Activity
10.1016/j.stem.2008.09.005 · ExternalCitation · doi-reference
Mouse Embryonic Head as a Site for Hematopoietic Stem Cell Development
10.1016/j.stem.2012.07.004 · ExternalCitation · doi-reference
Blood Development: Hematopoietic Stem Cell Dependence and Independence
10.1016/j.stem.2018.04.015 · ExternalCitation · doi-reference
Combined Single-Cell Profiling of lncRNAs and Functional Screening Reveals that H19 Is Pivotal for Embryonic Hematopoietic Stem Cell Development
10.1016/j.stem.2018.11.023 · ExternalCitation · doi-reference
Mathematical model of a gene regulatory network reconciles effects of genetic perturbations on hematopoietic stem cell emergence
10.1016/j.ydbio.2013.04.016 · ExternalCitation · doi-reference
Definitive hematopoiesis is autonomously initiated by the AGM region
10.1016/s0092-8674(00)80165-8 · ExternalCitation · doi-reference
Hematopoietic stem cells localize to the endothelial cell layer in the midgestation mouse aorta
10.1016/s1074-7613(02)00313-8 · ExternalCitation · doi-reference
A Small Molecule Inhibitor, 1,2,4,5-Benzenetetraamine Tetrahydrochloride, Targeting the Y397 Site of Focal Adhesion Kinase Decreases Tumor Growth
10.1021/jm800483v · ExternalCitation · doi-reference
N-myc over-expression downregulates alpha3beta1 integrin expression in human Saos-2 osteosarcoma cells
10.1023/a:1018417330479 · ExternalCitation · doi-reference
The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system
10.1038/nature03080 · ExternalCitation · doi-reference
Haematopoietic stem cells derive directly from aortic endothelium during development
10.1038/nature08738 · ExternalCitation · doi-reference
In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium
10.1038/nature08764 · ExternalCitation · doi-reference
A somitic Wnt16/Notch pathway specifies haematopoietic stem cells
10.1038/nature10107 · ExternalCitation · doi-reference
Tracing haematopoietic stem cell formation at single-cell resolution
10.1038/nature17997 · ExternalCitation · doi-reference
Integrative genomics viewer
10.1038/nbt.1754 · ExternalCitation · doi-reference
Of lineage and legacy: the development of mammalian hematopoietic stem cells
10.1038/ni1560 · ExternalCitation · doi-reference
Reversed graph embedding resolves complex single-cell trajectories
10.1038/nmeth.4402 · ExternalCitation · doi-reference
MYC: connecting selective transcriptional control to global RNA production
10.1038/nrc3984 · ExternalCitation · doi-reference
Interleukin-6 signaling regulates hematopoietic stem cell emergence
10.1038/s12276-019-0320-5 · ExternalCitation · doi-reference
MYCN and KAT2A form a feedforward loop to drive an oncogenic transcriptional program in neuroblastoma
10.1038/s41389-025-00557-2 · ExternalCitation · doi-reference
VE-Cadherin modulates β-catenin/TCF-4 to enhance Vasculogenic Mimicry
10.1038/s41419-023-05666-7 · ExternalCitation · doi-reference
Tracing the first hematopoietic stem cell generation in human embryo by single-cell RNA sequencing
10.1038/s41422-019-0228-6 · ExternalCitation · doi-reference
Embryonic endothelial evolution towards first hematopoietic stem cells revealed by single-cell transcriptomic and functional analyses
10.1038/s41422-020-0300-2 · ExternalCitation · doi-reference
Heterogeneity in endothelial cells and widespread venous arterialization during early vascular development in mammals
10.1038/s41422-022-00615-z · ExternalCitation · doi-reference
Let-7 microRNA-dependent control of leukotriene signaling regulates the transition of hematopoietic niche in mice
10.1038/s41467-017-00137-y · ExternalCitation · doi-reference
Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification
10.1038/s41467-017-01742-7 · ExternalCitation · doi-reference
Single-cell transcriptomics reveal the dynamic of haematopoietic stem cell production in the aorta
10.1038/s41467-018-04893-3 · ExternalCitation · doi-reference
Pre-configuring chromatin architecture with histone modifications guides hematopoietic stem cell formation in mouse embryos
10.1038/s41467-022-28018-z · ExternalCitation · doi-reference
Meis1 establishes the pre-hemogenic endothelial state prior to Runx1 expression
10.1038/s41467-023-40283-0 · ExternalCitation · doi-reference
Tracing the temporal-spatial transcriptome landscapes of the human fetal digestive tract using single-cell RNA-sequencing
10.1038/s41556-018-0105-4 · ExternalCitation · doi-reference
Target gene-independent functions of MYC oncoproteins
10.1038/s41580-020-0215-2 · ExternalCitation · doi-reference
Mapping human haematopoietic stem cells from haemogenic endothelium to birth
10.1038/s41586-022-04571-x · ExternalCitation · doi-reference
Programming multicellular assembly with synthetic cell adhesion molecules
10.1038/s41586-022-05622-z · ExternalCitation · doi-reference
Single-cell profiling reveals three endothelial-to-hematopoietic transitions with divergent isoform expression landscapes
10.1038/s44161-025-00740-z · ExternalCitation · doi-reference
Complementation of Myc-dependent cell proliferation by cDNA expression library screening
10.1038/sj.onc.1203880 · ExternalCitation · doi-reference
Activation of the TGFβ pathway impairs endothelial to haematopoietic transition
10.1038/srep21518 · ExternalCitation · doi-reference
Hierarchical organization and early hematopoietic specification of the developing HSC lineage in the AGM region
10.1084/jem.20102419 · ExternalCitation · doi-reference
Hematopoietic stem cell development requires transient Wnt/β-catenin activity
10.1084/jem.20120225 · ExternalCitation · doi-reference
clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters
10.1089/omi.2011.0118 · ExternalCitation · doi-reference
TopHat: discovering splice junctions with RNA-Seq
10.1093/bioinformatics/btp120 · ExternalCitation · doi-reference
BEDTools: a flexible suite of utilities for comparing genomic features
10.1093/bioinformatics/btq033 · ExternalCitation · doi-reference
N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis
10.1093/emboj/20.6.1383 · ExternalCitation · doi-reference
Twelve years of SAMtools and BCFtools
10.1093/gigascience/giab008 · ExternalCitation · doi-reference
deepTools2: a next generation web server for deep-sequencing data analysis
10.1093/nar/gkw257 · ExternalCitation · doi-reference
When blood development meets single-cell transcriptomics
10.1097/bs9.0000000000000007 · ExternalCitation · doi-reference
New insights into the endothelial origin of hematopoietic system inspired by “TIF” approaches
10.1097/bs9.0000000000000199 · ExternalCitation · doi-reference
Single-cell transcriptomic dissection of two waves of endothelial-hematopoietic transition in a murine yolk sac
10.1097/bs9.0000000000000260 · ExternalCitation · doi-reference
Neuroblastoma and MYCN
10.1101/cshperspect.a014415 · ExternalCitation · doi-reference
N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation
10.1101/gad.1021202 · ExternalCitation · doi-reference
Hematopoietic stem cell fate is established by the Notch-Runx pathway
10.1101/gad.1337005 · ExternalCitation · doi-reference
Inflammatory signaling regulates embryonic hematopoietic stem and progenitor cell production
10.1101/gad.253302.114 · ExternalCitation · doi-reference
c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation
10.1101/gad.313104 · ExternalCitation · doi-reference
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
10.1126/science.aad0501 · ExternalCitation · doi-reference
The Expanding World of N-MYC-Driven Tumors
10.1158/2159-8290.cd-17-0273 · ExternalCitation · doi-reference
ANGPTL2-containing small extracellular vesicles from vascular endothelial cells accelerate leukemia progression
10.1172/jci138986 · ExternalCitation · doi-reference
Runx1-mediated hematopoietic stem-cell emergence is controlled by a Gata/Ets/SCL-regulated enhancer
10.1182/blood-2007-07-100883 · ExternalCitation · doi-reference
RUNX1 positively regulates a cell adhesion and migration program in murine hemogenic endothelium prior to blood emergence
10.1182/blood-2014-04-572958 · ExternalCitation · doi-reference
Functional and molecular characterization of mouse Gata2-independent hematopoietic progenitors
10.1182/blood-2015-10-673749 · ExternalCitation · doi-reference
Inflammatory signals directly instruct PU.1 in HSCs via TNF
10.1182/blood-2018-02-832998 · ExternalCitation · doi-reference
Developmental trajectory of prehematopoietic stem cell formation from endothelium
10.1182/blood.2020004801 · ExternalCitation · doi-reference
Murine AGM single-cell profiling identifies a continuum of hemogenic endothelium differentiation marked by ACE
10.1182/blood.2020007885 · ExternalCitation · doi-reference
Deciphering the continuum of hemogenic endothelium differentiation
10.1182/blood.2021013853 · ExternalCitation · doi-reference
Heterogeneity of high-potency multilineage hematopoietic stem cells and identification of “Super” transplantability
10.1182/blood.2024027872 · ExternalCitation · doi-reference
Choice of pre-processing pipeline influences clustering quality of scRNA-seq datasets
10.1186/s12864-021-07930-6 · ExternalCitation · doi-reference
Analysis of endothelial-to-haematopoietic transition at the single cell level identifies cell cycle regulation as a driver of differentiation
10.1186/s13059-020-02058-4 · ExternalCitation · doi-reference
c-myc in the hematopoietic lineage is crucial for its angiogenic function in the mouse embryo
10.1242/dev.020131 · ExternalCitation · doi-reference
Ribosome biogenesis is essential for hemogenic endothelial cells to generate hematopoietic stem cells
10.1242/dev.202875 · ExternalCitation · doi-reference
MYCN drives oncogenesis by cooperating with the histone methyltransferase G9a and the WDR5 adaptor to orchestrate global gene transcription
10.1371/journal.pbio.3002240 · ExternalCitation · doi-reference
Focal Adhesion Remodeling Is Crucial for Glucose-Stimulated Insulin Secretion and Involves Activation of Focal Adhesion Kinase and Paxillin
10.2337/db10-0946 · ExternalCitation · doi-reference
Focal Adhesion Kinase (FAK) and c-Src Dependent Signal Transduction in Cell Adhesion
10.24976/discov.med.202436189.184 · ExternalCitation · doi-reference
MYCN, neuroblastoma and focal adhesion kinase (FAK)
10.2741/e257 · ExternalCitation · doi-reference
Hlf Expression Marks Early Emergence of Hematopoietic Stem Cell Precursors With Adult Repopulating Potential and Fate
10.3389/fcell.2021.728057 · ExternalCitation · doi-reference
A Review of the Regulatory Mechanisms of N-Myc on Cell Cycle
10.3390/molecules28031141 · ExternalCitation · doi-reference
A novel small molecule inhibitor of FAK decreases growth of human pancreatic cancer
10.4161/cc.8.15.9145 · ExternalCitation · doi-reference
Tuning apicobasal polarity and junctional recycling in the hemogenic endothelium orchestrates the morphodynamic complexity of emerging pre-hematopoietic stem cells
10.7554/elife.91429 · ExternalCitation · doi-reference
