References

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

10.1038/nature06553 · 2008 · External reference

The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral vpu protein

10.1016/j.chom.2008.03.001 · 2008 · External reference

Influenza virus partially counteracts restriction imposed by Tetherin/BST-2

10.1074/jbc.m111.319996 · 2012 · External reference

Interferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanisms

10.1128/jvi.01328-10 · 2010 · External reference

Inhibition of Lassa and Marburg virus production by tetherin

10.1128/jvi.01607-08 · 2009 · External reference

Molecular mechanism of BST2/tetherin downregulation by K5/MIR2 of Kaposi's sarcoma-associated herpesvirus

10.1128/jvi.00597-09 · 2009 · External reference

Broad-spectrum inhibition of retroviral and filoviral particle release by tetherin

10.1128/jvi.02211-08 · 2009 · External reference

Bst-2/HM1.24 is a raft-associated apical membrane protein with an unusual topology

10.1034/j.1600-0854.2003.00129.x · 2003 · External reference

Tetherin inhibits HIV-1 release by directly tethering virions to cells

10.1016/j.cell.2009.08.039 · 2009 · External reference

Immunoelectron microscopic evidence for tetherin/BST2 as the physical bridge between HIV-1 virions and the plasma membrane

10.1371/journal.ppat.1000749 · 2010 · External reference

Direct restriction of virus release and incorporation of the interferon-induced protein BST-2 into HIV-1 particles

10.1371/journal.ppat.1000701 · 2010 · External reference

BCA2/rabring7 promotes tetherin-dependent HIV-1 restriction

10.1371/journal.ppat.1000700 · 2009 · External reference

The HIV-1 Vpu protein: a multifunctional enhancer of viral particle release

10.1016/s1286-4579(03)00191-6 · 2003 · External reference

HIV-1 accessory protein Vpu internalizes cell-surface BST-2/tetherin through transmembrane interactions leading to lysosomes

10.1074/jbc.m109.058305 · 2009 · External reference

HIV-1 Vpu neutralizes the antiviral factor tetherin/BST-2 by binding it and directing its beta-TrCP2-dependent degradation

10.1371/journal.ppat.1000574 · 2009 · External reference

Antagonism of tetherin restriction of HIV-1 release by Vpu involves binding and sequestration of the restriction factor in a perinuclear compartment

10.1371/journal.ppat.1000856 · 2010 · External reference

Determinants of tetherin antagonism in the transmembrane domain of the human immunodeficiency virus type 1 Vpu protein

10.1128/jvi.01699-10 · 2010 · External reference

Vpu directs the degradation of the human immunodeficiency virus restriction factor BST-2/tetherin via a βTrCP-dependent mechanism

10.1128/jvi.00242-09 · 2009 · External reference

Vpu antagonizes BST-2-mediated restriction of HIV-1 release via β-TrCP and endo-lysosomal trafficking

10.1371/journal.ppat.1000450 · 2009 · External reference

Serine-threonine ubiquitination mediates downregulation of BST-2/tetherin and relief of restricted virion release by HIV-1 Vpu

10.1128/jvi.01795-10 · 2011 · External reference

The antiviral activities of tetherin

2013 · External reference

Suppression of Tetherin-restricting activity upon human immunodeficiency virus type 1 particle release correlates with localization of Vpu in the trans-Golgi network

10.1128/jvi.01800-08 · 2009 · External reference

Role of the endocytic pathway in the counteraction of BST-2 by human lentiviral pathogens

10.1128/jvi.02633-10 · 2011 · External reference

A cytoplasmic tail determinant in HIV-1 Vpu mediates targeting of tetherin for endosomal degradation and counteracts interferon-induced restriction

10.1371/journal.ppat.1002609 · 2012 · External reference

Species-specific activity of SIV Nef and HIV-1 Vpu in overcoming restriction by tetherin/BST2

10.1371/journal.ppat.1000429 · 2009 · External reference

Nef proteins from simian immunodeficiency viruses are tetherin antagonists

10.1016/j.chom.2009.05.008 · 2009 · External reference

Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains

10.1016/j.chom.2009.10.004 · 2009 · External reference

Antagonism to and intracellular sequestration of human tetherin by the human immunodeficiency virus type 2 envelope glycoprotein

10.1128/jvi.01515-09 · 2009 · External reference

Tetherin is a key effector of the antiretroviral activity of type I interferon in vitro and in vivo

10.1073/pnas.1113694108 · 2011 · External reference

Cutting edge: paradoxical roles of BST2/tetherin in promoting type I IFN response and viral infection

10.4049/jimmunol.1103145 · 2012 · External reference

A single nucleotide polymorphism in tetherin promotes retrovirus restriction in vivo

10.1371/journal.ppat.1002596 · 2012 · External reference

Human-specific adaptations in Vpu conferring anti-tetherin activity are critical for efficient early HIV-1 replication in vivo

10.1016/j.chom.2017.12.009 · 2018 · External reference

Cell-cell spread of human immunodeficiency virus type 1 overcomes tetherin/BST-2-mediated restriction in T cells

10.1128/jvi.01447-10 · 2010 · External reference

An in vitro rapid-turnover assay for human immunodeficiency virus type 1 replication selects for cell-to-cell spread of virus

10.1128/jvi.74.23.10882-10891.2000 · 2000 · External reference

Feline tetherin efficiently restricts release of feline immunodeficiency virus but not spreading of infection

10.1128/jvi.00071-11 · 2011 · External reference

Tetherin inhibits cell-free virus dissemination and retards murine leukemia virus pathogenesis

10.1128/jvi.02286-16 · 2017 · External reference

Compensatory changes in the cytoplasmic tail of gp41 confer resistance to tetherin/BST-2 in a pathogenic nef-deleted SIV

10.1016/j.chom.2010.12.005 · 2011 · External reference

Reacquisition of Nef-mediated tetherin antagonism in a single in vivo passage of HIV-1 through its original chimpanzee host

10.1016/j.chom.2012.07.008 · 2012 · External reference

HIV-1-induced AIDS in monkeys

10.1126/science.1250761 · 2014 · External reference

Loss of tetherin antagonism by Nef impairs SIV replication during acute infection of rhesus macaques

10.1371/journal.ppat.1008487 · 2020 · External reference

Tetherin antagonism by Vpu protects HIV-infected cells from antibody-dependent cell-mediated cytotoxicity

10.1073/pnas.1321507111 · 2014 · External reference

HIV-1 Vpu antagonism of tetherin inhibits antibody-dependent cellular cytotoxic responses by natural killer cells

10.1128/jvi.00449-14 · 2014 · External reference

HIV Nef and Vpu protect HIV-infected CD4+ T cells from antibody-mediated cell lysis through down-modulation of CD4 and BST2

10.1186/1742-4690-11-15 · 2014 · External reference

Potent broadly neutralizing antibodies mediate efficient antibody-dependent phagocytosis of HIV-infected cells

10.1371/journal.ppat.1012665 · 2024 · External reference

Interaction between the cytoplasmic domains of HIV-1 Vpu and CD4: role of Vpu residues involved in CD4 interaction and in vitro CD4 degradation

10.1006/viro.1996.0491 · 1996 · External reference

A diverse range of gene products are effectors of the type I interferon antiviral response

10.1038/nature09907 · 2011 · External reference

Innate immunity against HIV-1 infection

10.1038/ni.3157 · 2015 · External reference

Identification of alternatively translated tetherin isoforms with differing antiviral and signaling activities

10.1371/journal.ppat.1002931 · 2012 · External reference

Differential sensitivities of tetherin isoforms to counteraction by primate lentiviruses

10.1128/jvi.03818-13 · 2014 · External reference

Efficient BST2 antagonism by Vpu is critical for early HIV-1 dissemination in humanized mice

10.1186/1742-4690-10-128 · 2013 · External reference

Upregulation of BST-2 by type I interferons reduces the capacity of Vpu to protect HIV-1-infected cells from NK cell responses

10.1128/mbio.01113-19 · 2019 · External reference

Tetherin promotes the innate and adaptive cell-mediated immune response against retrovirus infection in vivo

10.4049/jimmunol.1400490 · 2014 · External reference

Tetherin/BST-2 promotes dendritic cell activation and function during acute retrovirus infection

2016 · External reference

Innate sensing of HIV-1 assembly by tetherin induces NFκB-dependent proinflammatory responses

10.1016/j.chom.2012.10.007 · 2012 · External reference

Stimulation of NF-κB activity by the HIV restriction factor BST2

10.1128/jvi.02272-12 · 2013 · External reference

Retroviral retention activates a Syk-dependent HemITAM in human tetherin

10.1016/j.chom.2014.08.005 · 2014 · External reference

Nonhuman lentiviruses

2022 · External reference

BST-2/tetherin: a new component of the innate immune response to enveloped viruses

10.1016/j.tim.2010.06.010 · 2010 · External reference

Dissecting polyclonal vaccine-induced humoral immunity against HIV using systems serology

10.1016/j.cell.2015.10.027 · 2015 · External reference

Antibody Fc effector functions and IgG3 associate with decreased HIV-1 risk

10.1172/jci126391 · 2019 · External reference

Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis

10.1038/s41467-022-28250-7 · 2022 · External reference

Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV

10.1038/s41591-018-0161-0 · 2018 · External reference

Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeys

10.1126/science.aab3886 · 2015 · External reference

Protective efficacy of a global HIV-1 mosaic vaccine against heterologous SHIV challenges in rhesus monkeys

10.1016/j.cell.2013.09.061 · 2013 · External reference

Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge

10.1038/ncomms15711 · 2017 · External reference

Adjuvanted HIV-1 vaccine promotes antibody-dependent phagocytic responses and protects against heterologous SHIV challenge

10.1371/journal.ppat.1008764 · 2020 · External reference

A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples

10.1016/j.jim.2010.12.016 · 2011 · External reference

Antibody-dependent cellular phagocytosis in antiviral immune responses

10.3389/fimmu.2019.00332 · 2019 · External reference

Non-neutralizing antibodies directed against HIV and their functions

10.3389/fimmu.2017.01590 · 2017 · External reference

Crystal structure of a soluble cleaved HIV-1 envelope trimer

10.1126/science.1245625 · 2013 · External reference

Three-dimensional structures of soluble CD4-bound states of trimeric simian immunodeficiency virus envelope glycoproteins determined by using cryo-electron tomography

10.1128/jvi.05297-11 · 2011 · External reference

Antibody neutralization and escape by HIV-1

10.1038/nature01470 · 2003 · External reference

HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

10.1038/nature01188 · 2002 · External reference

Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus

10.1038/s41467-022-32783-2 · 2022 · External reference

Cryo-EM structures of prefusion SIV envelope trimer

10.1038/s41594-022-00852-1 · 2022 · External reference

Interaction with cellular CD4 exposes HIV-1 envelope epitopes targeted by antibody-dependent cell-mediated cytotoxicity

10.1128/jvi.03230-13 · 2014 · External reference

CD4 mimetics sensitize HIV-1-infected cells to ADCC

10.1073/pnas.1506755112 · 2015 · External reference

Interaction of endocytic signals from the HIV-1 envelope glycoprotein complex with members of the adaptor medium chain family

10.1006/viro.1997.8839 · 1997 · External reference

An internalization signal in the simian immunodeficiency virus transmembrane protein cytoplasmic domain modulates expression of envelope glycoproteins on the cell surface

10.1083/jcb.132.5.795 · 1996 · External reference

Envelope glycoprotein internalization protects human and simian immunodeficiency virus-infected cells from antibody-dependent cell-mediated cytotoxicity

10.1128/jvi.01911-15 · 2015 · External reference

HIV-1 Vpu promotes phagocytosis of infected CD4+ T cells by macrophages through downregulation of CD47

10.1128/mbio.01920-21 · 2021 · External reference

Integrin-associated protein (CD47) and its ligands

10.1016/s0962-8924(00)01906-1 · 2001 · External reference

Novel compound inhibitors of HIV-1NL4-3 Vpu

10.3390/v14040817 · 2022 · External reference

Broad neutralization coverage of HIV by multiple highly potent antibodies

10.1038/nature10373 · 2011 · External reference

Functional and molecular characterization of human monoclonal antibody reactive with the immunodominant region of HIV type 1 glycoprotein 41

10.1089/aid.1998.14.1271 · 1998 · External reference

Generation of transmitted/founder HIV-1 infectious molecular clones and characterization of their replication capacity in CD4 T lymphocytes and monocyte-derived macrophages

10.1128/jvi.06157-11 · 2012 · External reference

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

10.1128/jvi.59.2.284-291.1986 · 1986 · External reference

Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms

10.1126/science.3646751 · 1987 · External reference

Easy quantitative assessment of genome editing by sequence trace decomposition

10.1093/nar/gku936 · 2014 · External reference

Novel human IgG1 and IgG4 Fc-engineered antibodies with completely abolished immune effector functions

10.1093/protein/gzw040 · 2016 · External reference

Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding

10.1128/jvi.74.21.10074-10080.2000 · 2000 · External reference