Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Research graph
References from An extramedullary bone model of metastatic dormancy reveals an increased rate of metastatic reactivation upon distant insults. Local targets link to admitted publications; unresolved targets remain external evidence.
Metastasis
10.1016/j.cell.2023.03.003 · 2023 · External reference
The force awakens: metastatic dormant cancer cells
10.1038/s12276-020-0423-z · 2020 · External reference
Cellular Mechanisms and Regulation of Quiescence
10.1016/j.devcel.2020.09.029 · 2020 · External reference
Metastatic Latency and Immune Evasion through Autocrine Inhibition of WNT
10.1016/j.cell.2016.02.025 · 2016 · External reference
An NR2F1-specific agonist suppresses metastasis by inducing cancer cell dormancy
10.1084/jem.20210836 · 2022 · External reference
MacroH2A impedes metastatic growth by enforcing a discrete dormancy program in disseminated cancer cells
10.1126/sciadv.abo0876 · 2022 · External reference
The current paradigm and challenges ahead for the dormancy of disseminated tumor cells
10.1038/s43018-020-0088-5 · 2020 · External reference
Persistence of Disseminated Tumor Cells in the Bone Marrow of Breast Cancer Patients Predicts Increased Risk for Relapse—A European Pooled Analysis
10.1158/1078-0432.ccr-10-2515 · 2011 · External reference
Mechanisms of disseminated cancer cell dormancy: an awakening field
10.1038/nrc3793 · 2014 · External reference
Axl is required for TGF-β2-induced dormancy of prostate cancer cells in the bone marrow
10.1038/srep36520 · 2016 · External reference
Bone morphogenetic protein 7 in dormancy and metastasis of prostate cancer stem-like cells in bone
10.1084/jem.20110840 · 2011 · External reference
The perivascular niche regulates breast tumour dormancy
10.1038/ncb2767 · 2013 · External reference
Osteoclasts control reactivation of dormant myeloma cells by remodelling the endosteal niche
10.1038/ncomms9983 · 2015 · External reference
VCAM-1 Promotes Osteolytic Expansion of Indolent Bone Micrometastasis of Breast Cancer by Engaging α4β1-Positive Osteoclast Progenitors
10.1016/j.ccr.2011.11.002 · 2011 · External reference
A tumor-derived type III collagen-rich ECM niche regulates tumor cell dormancy
10.1038/s43018-021-00291-9 · 2022 · External reference
Bone marrow NG2+/Nestin+ mesenchymal stem cells drive DTC dormancy via TGF-β2
10.1038/s43018-021-00179-8 · 2021 · External reference
Bone-matrix mineralization dampens integrin-mediated mechanosignalling and metastatic progression in breast cancer
10.1038/s41551-023-01077-3 · 2023 · External reference
The sleeping ugly: Tumour microenvironment’s act to make or break the spell of dormancy
10.1016/j.bbcan.2017.05.002 · 2017 · External reference
Stromal changes in the aged lung induce an emergence from melanoma dormancy
10.1038/s41586-022-04774-2 · 2022 · External reference
Age-associated microenvironmental changes highlight the role of PDGF-C in ER+ breast cancer metastatic relapse
10.1038/s43018-023-00525-y · 2023 · External reference
The systemic response to surgery triggers the outgrowth of distant immune-controlled tumors in mouse models of dormancy
10.1126/scitranslmed.aan3464 · 2018 · External reference
Bone Metastasis Initiation Is Coupled with Bone Remodeling through Osteogenic Differentiation of NG2+ Cells
10.1158/2159-8290.cd-22-0220 · 2023 · External reference
Optimization of a syngeneic murine model of bone metastasis
10.1016/j.jbo.2020.100298 · 2020 · External reference
Intratibial Injection Causes Direct Pulmonary Seeding of Osteosarcoma Cells and Is Not a Spontaneous Model of Metastasis
10.1007/s11999.0000000000000291 · 2018 · External reference
Identification and Specification of the Mouse Skeletal Stem Cell
10.1016/j.cell.2014.12.002 · 2015 · External reference
Versatile humanized niche model enables study of normal and malignant human hematopoiesis
10.1172/jci89364 · 2017 · External reference
Ectopic Humanized Mesenchymal Niche in Mice Enables Robust Engraftment of Myelodysplastic Stem CellsHumanized Niches Support Myelodysplastic Stem Cells
10.1158/2643-3230.bcd-20-0161 · 2021 · External reference
Modeling the chondrocyte-derived osteoblasts formation process reveals its molecular signature and regulation network
10.1038/s41413-025-00500-6 · 2026 · External reference
Engineering human mini-bones for the standardized modeling of healthy hematopoiesis, leukemia, and solid tumor metastasis
10.1126/scitranslmed.abm6391 · 2022 · External reference
A tissue-engineered humanized xenograft model of human breast cancer metastasis to bone
10.1242/dmm.014076 · 2014 · External reference
Hepatic stellate cells suppress NK cell-sustained breast cancer dormancy
10.1038/s41586-021-03614-z · 2021 · External reference
Lung-resident alveolar macrophages regulate the timing of breast cancer metastasis
10.1016/j.cell.2024.09.016 · 2024 · External reference
Primary culture and phenotyping of murine chondrocytes
10.1038/nprot.2008.95 · 2008 · External reference
Endothelial proteolytic activity and interaction with non-resorbing osteoclasts mediate bone elongation
10.1038/s41556-019-0304-7 · 2019 · External reference
Long-Term Engraftment of Primary Bone Marrow Stromal Cells Repairs Niche Damage and Improves Hematopoietic Stem Cell Transplantation
10.1016/j.stem.2017.07.004 · 2017 · External reference
Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone
10.1038/nature13145 · 2014 · External reference
A novel cell-cycle-indicator, mVenus-p27K−, identifies quiescent cells and visualizes G0–G1 transition
10.1038/srep04012 · 2014 · External reference
Cell dormancy plasticity: quiescence deepens into senescence through a dimmer switch
10.1152/physiolgenomics.00068.2020 · 2020 · External reference
Autophagy mediates serum starvation-induced quiescence in nucleus pulposus stem cells by the regulation of P27
10.1186/s13287-019-1219-8 · 2019 · External reference
Single-cell transcriptional diversity is a hallmark of developmental potential
10.1126/science.aax0249 · 2020 · External reference
RNA velocity of single cells
10.1038/s41586-018-0414-6 · 2018 · External reference
Dextran Sulfate Sodium (DSS)-Induced Colitis in Mice
10.1002/0471142735.im1525s104 · 2014 · External reference
Enhanced production of early lineages of monocytic and granulocytic cells in mice with colitis
10.1073/pnas.1213854109 · 2012 · External reference
Obesity alters the lung myeloid cell landscape to enhance breast cancer metastasis through IL5 and GM-CSF
10.1038/ncb3578 · 2017 · External reference
NicheNet: modeling intercellular communication by linking ligands to target genes
10.1038/s41592-019-0667-5 · 2020 · External reference
Tumor-derived HMGB1 induces CD62Ldim neutrophil polarization and promotes lung metastasis in triple-negative breast cancer
10.1038/s41389-020-00267-x · 2020 · External reference
The double life of HMGB1 chromatin protein: architectural factor and extracellular signal
10.1093/emboj/20.16.4337 · 2001 · External reference
High mobility group B2 is secreted by myeloid cells and has mitogenic and chemoattractant activities similar to high mobility group B1
10.1080/08916930902831845 · 2009 · External reference
Spatiotemporal expression of HMGB2 regulates cell proliferation and hepatocyte size during liver regeneration
10.1038/s41598-022-16258-4 · 2022 · External reference
The Prognostic Role of a Gene Signature from Tumorigenic Breast-Cancer Cells
10.1056/nejmoa063994 · 2007 · External reference
As part of the Boston Bone Metastases Consortium. Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment
10.1016/j.ccell.2021.09.005 · 2021 · External reference
Detection of disseminated tumor cells in bone marrow predict late recurrences in operable breast cancer patients
10.1186/s12885-019-6268-y · 2019 · External reference
Incidence of bone metastases in patients with solid tumors: analysis of oncology electronic medical records in the United States
10.1186/s12885-017-3922-0 · 2018 · External reference
Framework models of tumor dormancy from patient-derived observations
10.1016/j.gde.2010.10.011 · 2011 · External reference
Immune evasion of dormant disseminated tumor cells is due to their scarcity and can be overcome by T cell immunotherapies
10.1016/j.ccell.2023.12.011 · 2024 · External reference
Lung endothelium exploits susceptible tumor cell states to instruct metastatic latency
10.1038/s43018-023-00716-7 · 2024 · External reference
A vertebral skeletal stem cell lineage driving metastasis
10.1038/s41586-023-06519-1 · 2023 · External reference
Mammary tumour cells remodel the bone marrow vascular microenvironment to support metastasis
10.1038/s41467-021-26556-6 · 2021 · External reference
Interplay between RAGE, CD44, and focal adhesion molecules in epithelial-mesenchymal transition of alveolar epithelial cells
10.1152/ajplung.00230.2010 · 2011 · External reference
Elevated Biomarkers of Inflammation Are Associated With Reduced Survival Among Breast Cancer Patients
10.1200/jco.2008.18.9068 · 2009 · External reference
The relationship between post-surgery infection and breast cancer recurrence
10.1016/j.jhin.2020.08.004 · 2020 · External reference
Models of Bone Metastasis
2012 · External reference
QuPath: Open source software for digital pathology image analysis
10.1038/s41598-017-17204-5 · 2017 · External reference
Massively parallel digital transcriptional profiling of single cells
10.1038/ncomms14049 · 2017 · External reference
STAR: ultrafast universal RNA-seq aligner
10.1093/bioinformatics/bts635 · 2012 · External reference
Comprehensive Integration of Single-Cell Data
10.1016/j.cell.2019.05.031 · 2019 · External reference
glmGamPoi: fitting Gamma-Poisson generalized linear models on single cell count data
10.1093/bioinformatics/btaa1009 · 2020 · External reference
clusterProfiler 4.0: A universal enrichment tool for interpreting omics data
2021 · External reference
Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage
10.1038/s41590-018-0276-y · 2019 · External reference