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References from Bacterial endosymbiont suppresses detoxification through folate-mediated DNA methylation in Nilaparvata lugens. Local targets link to admitted publications; unresolved targets remain external evidence.
A genomic perspective on nutrient provisioning by bacterial symbionts of insects
10.1073/pnas.2135345100 · 2003 · External reference
Insect Bacteriocytes: Adaptation, Development, and Evolution
10.1146/annurev-ento-010323-124159 · 2024 · External reference
Evolutionary origin of insect-Wolbachia nutritional mutualism
10.1073/pnas.1409284111 · 2014 · External reference
Wolbachia supplement biotin and riboflavin to enhance reproduction in planthoppers
10.1038/s41396-019-0559-9 · 2020 · External reference
A rapidly spreading deleterious aphid endosymbiont that uses horizontal as well as vertical transmission
10.1073/pnas.2217278120 · 2023 · External reference
Heritable symbiont producing nonribosomal peptide confers extreme heat sensitivity and antifungal protection on its host
10.1073/pnas.2509873122 · 2025 · External reference
The role of microbiomes in shaping insecticide resistance: current insights and emerging paradigms
2025 · External reference
Symbiotic bacteria and pest control: plant toxins, chemical pesticides, and fungal entomopathogens
10.1016/j.tim.2025.04.007 · 2025 · External reference
Fitness costs of infection with Serratia symbiotica are associated with greater susceptibility to insecticides in the pea aphid Acyrthosiphon pisum
10.1002/ps.4881 · 2018 · External reference
Relationship between Wolbachia infection in Culex quinquefasciatus and its resistance to insecticide
10.1016/j.heliyon.2021.e06749 · 2021 · External reference
Arsenophonus, an emerging clade of intracellular symbionts with a broad host distribution
10.1186/1471-2180-9-143 · 2009 · External reference
Evolution and diversity of Arsenophonus endosymbionts in aphids
10.1111/mec.12092 · 2013 · External reference
Male-killing bacteria in a parasitic wasp
10.1126/science.3945814 · 1986 · External reference
A bacterium targets maternally inherited centrosomes to kill males in Nasonia
10.1016/j.cub.2008.07.093 · 2008 · External reference
To B or Not to B: Comparative genomics suggests Arsenophonus as a source of B Vitamins in Whiteflies
10.3389/fmicb.2018.02254 · 2018 · External reference
Intracellular symbionts drive sex ratio in the whitefly by facilitating fertilization and provisioning of B vitamins
10.1038/s41396-020-0717-0 · 2020 · External reference
Infections with Arsenophonus facultative endosymbionts alter performance of aphids (Aphis gossypii) on an amino-acid-deficient diet
10.1128/aem.01407-19 · 2019 · External reference
Arsenophonus: A double-edged sword of aphid defense against parasitoids
10.3390/insects14090763 · 2023 · External reference
Insecticide susceptibility in a planthopper pest increases following inoculation with cultured Arsenophonus
10.1093/ismejo/wrae194 · 2024 · External reference
A distinct strain of Arsenophonus symbiont decreases insecticide resistance in its insect host
10.1371/journal.pgen.1007725 · 2018 · External reference
Molecular mechanisms of metabolic resistance to synthetic and natural xenobiotics
10.1146/annurev.ento.51.110104.151104 · 2007 · External reference
Wolbachia enhances expression of NlCYP4CE1 in Nilaparvata lugens in response to imidacloprid stress
10.1111/1744-7917.12834 · 2021 · External reference
Gut microbiota-derived butyrate primes systemic immunity in honey bees by mediating lipid metabolic reprogramming
10.1038/s41467-026-69073-0 · 2026 · External reference
A natural symbiotic bacterium drives mosquito refractoriness to Plasmodium infection via secretion of an antimalarial lipase
10.1038/s41564-021-00899-8 · 2021 · External reference
Coordination of host and symbiont gene expression reveals a metabolic tug-of-war between aphids and Buchnera
10.1073/pnas.1916748117 · 2020 · External reference
Activiation of the nitric oxide cycle by citrulline and arginine restores susceptibility of resistant brown planthoppers to the insecticide imidacloprid
10.1016/j.jhazmat.2020.122755 · 2020 · External reference
The B vitamin nutrition of insects: the contributions of diet, microbiome and horizontally acquired genes
10.1016/j.cois.2017.07.012 · 2017 · External reference
New Insights into Folate-Vitamin B12 Interactions
10.1146/annurev-nutr-120524-043056 · 2025 · External reference
Folate and DNA methylation: a review of molecular mechanisms and the evidence for folate's role
10.3945/an.111.000992 · 2012 · External reference
Folic acid protects against isoniazid-induced liver injury via the m6A RNA methylation of cytochrome P450 2E1 in mice
10.3389/fnut.2024.1389684 · 2024 · External reference
Neofunctionalization of Duplicated P450 Genes Drives the Evolution of Insecticide Resistance in the Brown Planthopper
10.1016/j.cub.2017.11.060 · 2018 · External reference
Histone methylation dynamics and gene regulation occur through the sensing of one-carbon metabolism
10.1016/j.cmet.2015.08.024 · 2015 · External reference
Creation of folate-biofortified rice by simultaneously enhancing biosynthetic flux and blocking folate oxidation
10.1016/j.molp.2024.09.005 · 2024 · External reference
Diversity and function of arthropod endosymbiont toxins
10.1016/j.tim.2021.06.008 · 2022 · External reference
Gut symbiont-derived anandamide promotes reward learning in honeybees by activating the endocannabinoid pathway
10.1016/j.chom.2024.09.013 · 2024 · External reference
Nymphal feeding suppresses oviposition-induced indirect plant defense in rice
10.1038/s41467-025-55816-y · 2025 · External reference
Microbiome variation correlates with the insecticide susceptibility in different geographic strains of a significant agricultural pest, Nilaparvata lugens
10.1038/s41522-023-00369-5 · 2023 · External reference
Bacteria-derived short-chain fatty acids as potential regulators of fungal commensalism and pathogenesis
10.1016/j.tim.2024.04.004 · 2024 · External reference
Mobile resistance elements: Symbionts that modify insect host resistance
10.1021/acs.jafc.4c10828 · 2025 · External reference
Cooperative microbial metabolism enhances tryptophan-mediated insecticide detoxification in the fall armyworm
10.1093/ismejo/wraf237 · 2025 · External reference
One-Carbon Metabolism in Health and Disease
10.1016/j.cmet.2016.08.009 · 2017 · External reference
“Wigglesworthia morsitans” Folate [Vitamin B9] biosynthesis contributes to tsetse host fitness
10.1128/aem.00553-15 · 2015 · External reference
Metabolic coevolution in the bacterial symbiosis of Whiteflies and related plant sap-feeding insects
10.1093/gbe/evv170 · 2015 · External reference
Genomic and transcriptomic analyses reveal metabolic complementarity between whiteflies and their symbionts
10.1111/1744-7917.12943 · 2022 · External reference
Transcriptional regulation of xenobiotic detoxification genes in insects - An overview
10.1016/j.pestbp.2021.104822 · 2021 · External reference
Epigenetic regulations as drivers of insecticide resistance and resilience to climate change in arthropod pests
2022 · External reference
Epitranscriptomic regulation of insecticide resistance
2021 · External reference
Insecticide exposure affects intergenerational patterns of DNA methylation in the Colorado potato beetle
10.1111/eva.13153 · 2021 · External reference
m6A-Mediated regulation of CYP417B1 contributes to imidacloprid resistance in Bemisia tabaci
10.1021/acs.jafc.5c04654 · 2025 · External reference
Heritable epigenomic modifications influence stress resilience and rapid adaptations in the Brown Planthopper (Nilaparvata lugens)
10.3390/ijms23158728 · 2022 · External reference
Wnt signaling modulates the response to DNA damage in the Drosophila wing imaginal disc by regulating the EGFR pathway
10.1371/journal.pbio.3002547 · 2024 · External reference
Cytochrome P450 associated with insecticide resistance catalyzes cuticular hydrocarbon production in Anopheles gambiae
10.1073/pnas.1608295113 · 2016 · External reference
Modern approaches to study plant–insect interactions in chemical ecology
10.1038/s41570-018-0009-7 · 2018 · External reference
The bitter truth: how insects cope with toxic plant alkaloids
10.1093/jxb/erae312 · 2025 · External reference
Conifer flavonoid compounds inhibit detoxification enzymes and synergize insecticides
10.1016/j.pestbp.2015.09.003 · 2016 · External reference
Plant defense metabolites influence the interaction between an insect herbivore and an entomovirus
10.1016/j.cub.2024.10.068 · 2024 · External reference
Plant secondary metabolites against biotic stresses for sustainable crop protection
10.1016/j.biotechadv.2025.108520 · 2025 · External reference
CRISPR technologies for precise epigenome editing
10.1038/s41556-020-00620-7 · 2021 · External reference
Upregulation of a cytochrome P450 gene, CYP6B50, confers multi-insecticide resistance in Spodoptera frugiperda
10.1016/j.jare.2025.06.083 · 2026 · External reference
Overexpression of multiple cytochrome P450 genes associated with sulfoxaflor resistance in Aphis gossypii Glover
10.1016/j.pestbp.2019.03.021 · 2019 · External reference
JNK-ERK synergistic regulation of P450 gene expression confers nitenpyram resistance in Nilaparvata lugens (Stål)
10.1021/acs.jafc.5c00803 · 2025 · External reference
Current susceptibilities of brown planthopper Nilaparvata lugens to triflumezopyrim and other frequently used insecticides in China
10.1111/1744-7917.12764 · 2021 · External reference
A simple and sensitive assay of 7-ethoxycoumarin deethylation
10.1016/0003-2697(78)90245-2 · 1978 · External reference
Overexpression of CYP6ER1 associated with clothianidin resistance in Nilaparvata lugens (Stål)
10.1016/j.pestbp.2018.12.008 · 2019 · External reference
Analysis of relative gene expression data using real-time quantitative PCR and the 2−ΔΔCT Method
10.1006/meth.2001.1262 · 2001 · External reference
5mC modification orchestrates choriogenesis and fertilization by preventing prolonged ftz-f1 expression
10.1038/s41467-023-43987-5 · 2023 · External reference
Marked methylation changes in intestinal genes during the perinatal period of preterm neonates
10.1186/1471-2164-15-716 · 2014 · External reference
