Research graph
References from Oleic acid might induce necroptosis of CD4+ T cells, in addition to its induction of pyroptosis. Local targets link to admitted publications; unresolved targets remain external evidence.
Lipid droplet-induced T cell death sustains autoimmune tissue inflammation
10.1016/j.cmet.2026.01.014 · 2026 · External reference
Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis
10.1038/s41586-019-1770-6 · 2019 · External reference
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
10.1038/nature09857 · 2011 · External reference
Catalytic activity of the caspase-8-FLIPL complex inhibits RIPK3-dependent necrosis
10.1038/nature09852 · 2011 · External reference
SIGLEC12 mediates plasma membrane rupture during necroptotic cell death
10.1038/s41586-025-09741-1 · 2026 · External reference
Palmitate induces RIP1/RIP3-dependent necrosis via MLKL-mediated pore formation in the plasma membrane of RAW 264.7 cells
10.1016/j.bbrc.2016.11.068 · 2017 · External reference
PGAM5 regulates DRP1-mediated mitochondrial fission/mitophagy flux in lipid overload-induced renal tubular epithelial cell necroptosis
10.1016/j.toxlet.2022.10.003 · 2023 · External reference
Activation of necroptosis in a rat model of acute respiratory distress syndrome induced by oleic acid
2016 · External reference
Necrostatin-1 protects against oleic acid-induced acute respiratory distress syndrome in rats
10.1016/j.bbrc.2016.08.163 · 2016 · External reference
NINJ1 mediates plasma membrane rupture during lytic cell death
10.1038/s41586-021-03218-7 · 2021 · External reference
