Research graph
References from Fungus Rhizopus arrhizus promotes MASLD-associated hepatocellular carcinoma through generating kynurenic acid. Local targets link to admitted publications; unresolved targets remain external evidence.
Metabolic dysfunction-associated steatotic liver disease in adults
10.1038/s41572-025-00599-1 · 2025 · External reference
Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention
10.1038/s41575-020-00381-6 · 2021 · External reference
Gut microbiome in metabolic dysfunction-associated steatotic liver disease and associated hepatocellular carcinoma
10.1038/s41575-025-01089-1 · 2025 · External reference
Dietary cholesterol drives fatty liver-associated liver cancer by modulating gut microbiota and metabolites
10.1136/gutjnl-2019-319664 · 2021 · External reference
Hepatocellular Carcinoma Is Associated With Gut Microbiota Profile and Inflammation in Nonalcoholic Fatty Liver Disease
10.1002/hep.30036 · 2019 · External reference
Gut microbiota impact on the peripheral immune response in non-alcoholic fatty liver disease related hepatocellular carcinoma
10.1038/s41467-020-20422-7 · 2021 · External reference
Gut mycobiome in metabolic diseases: Mechanisms and clinical implication
10.1016/j.bj.2023.100625 · 2024 · External reference
A genomic compendium of cultivated human gut fungi characterizes the gut mycobiome and its relevance to common diseases
10.1016/j.cell.2024.04.043 · 2024 · External reference
The fecal mycobiome in non-alcoholic fatty liver disease
10.1016/j.jhep.2021.11.029 · 2022 · External reference
A symbiotic filamentous gut fungus ameliorates MASH via a secondary metabolite-CerS6-ceramide axis
10.1126/science.adp5540 · 2025 · External reference
Candida albicans-specific Th17 cell-mediated response contributes to alcohol-associated liver disease
10.1016/j.chom.2023.02.001 · 2023 · External reference
Commensal Fungi Recapitulate the Protective Benefits of Intestinal Bacteria
10.1016/j.chom.2017.10.013 · 2017 · External reference
IQGAP1 is a scaffold for mitogen-activated protein kinase signaling
10.1128/mcb.25.18.7940-7952.2005 · 2005 · External reference
Cancer-associated fibroblasts regulate mitochondrial metabolism and inhibit chemosensitivity via ANGPTL4-IQGAP1 axis in prostate cancer
10.1016/j.jare.2024.12.003 · 2024 · External reference
Obesity, insulin resistance, NASH and hepatocellular carcinoma
10.1016/j.semcancer.2013.07.003 · 2013 · External reference
Epidemiology of Hepatocellular Carcinoma
10.1002/hep.31288 · 2021 · External reference
The Role of Gut-Liver Axis in Gut Microbiome Dysbiosis Associated NAFLD and NAFLD-HCC
10.3390/biomedicines10030524 · 2022 · External reference
Early-life gut mycobiome core species modulate metabolic health in mice
10.1038/s41467-025-56743-8 · 2025 · External reference
Mucosal fungi promote gut barrier function and social behavior via Type 17 immunity
10.1016/j.cell.2022.01.017 · 2022 · External reference
Landscape of the gut mycobiome dynamics during pregnancy and its relationship with host metabolism and pregnancy health
10.1136/gutjnl-2024-332260 · 2024 · External reference
Host-Pathogen Molecular Factors Contribute to the Pathogenesis of Rhizopus spp. in Diabetes Mellitus
10.1007/s40475-020-00222-1 · 2021 · External reference
Rhizopus arrhizus
10.1016/j.tim.2023.03.013 · 2023 · External reference
Rhizopus arrhizus infection in mice causes brain histopathological alterations and exacerbates neuronal apoptosis
10.1016/j.micpath.2023.106532 · 2024 · External reference
Pathogenesis of mucormycosis
10.1093/cid/cir865 · 2012 · External reference
Revisiting the association between candidal infection and carcinoma, particularly oral squamous cell carcinoma
10.3402/jom.v2i0.5780 · 2010 · External reference
The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL
10.1038/s41586-019-1608-2 · 2019 · External reference
The intratumor mycobiome promotes lung cancer progression via myeloid-derived suppressor cells
10.1016/j.ccell.2023.08.012 · 2023 · External reference
Sterols isolated from Nuruk (Rhizopus oryzae KSD-815) inhibit the migration of cancer cells
10.4014/jmb.0902.072 · 2009 · External reference
Rearranged diterpenoids from the biotransformation of ent-trachyloban-18-oic acid by Rhizopus arrhizus
10.1021/np100145n · 2010 · External reference
Ethyl acetate subfractions from ethanol extracts of fermented oats (Avena sativa L.) exert anti-cancer properties in vitro and in vivo through G2/M and S Phase arrest and apoptosis
10.7150/jca.48993 · 2021 · External reference
Kynurenic acid and cancer: facts and controversies
10.1007/s00018-019-03332-w · 2020 · External reference
The XOR-IDH3α axis controls macrophage polarization in hepatocellular carcinoma
10.1016/j.jhep.2023.06.022 · 2023 · External reference
Role of Kynurenine and Its Derivatives in Liver Diseases: Recent Advances and Future Clinical Perspectives
10.3390/ijms26030968 · 2025 · External reference
IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase-driven tumors
10.1038/nm.3165 · 2013 · External reference
Fructose-1,6-bisphosphatase Inhibits ERK Activation and Bypasses Gemcitabine Resistance in Pancreatic Cancer by Blocking IQGAP1-MAPK Interaction
10.1158/0008-5472.can-16-3143 · 2017 · External reference
MAPK/ERK Signaling Pathway in Hepatocellular Carcinoma
10.3390/cancers13123026 · 2021 · External reference
Targeting the MAPK Pathway in KRAS-Driven Tumors
10.1016/j.ccell.2020.03.013 · 2020 · External reference
Hepatocellular carcinoma: signaling pathways, targeted therapy, and immunotherapy
10.1002/mco2.474 · 2024 · External reference
Bifidobacterium pseudolongum-generated acetate suppresses non-alcoholic fatty liver disease-associated hepatocellular carcinoma
10.1016/j.jhep.2023.07.005 · 2023 · External reference
Gut bacteria alleviate smoking-related NASH by degrading gut nicotine
10.1038/s41586-022-05299-4 · 2022 · External reference
Gut symbionts alleviate MASH through a secondary bile acid biosynthetic pathway
10.1016/j.cell.2024.03.034 · 2024 · External reference
Positional expression profiling indicates candidate genes in deletion hotspots of hepatocellular carcinoma
10.1038/modpathol.3800674 · 2006 · External reference
Generation and analysis of genetically defined liver carcinomas derived from bipotential liver progenitors
10.1101/sqb.2005.70.059 · 2005 · External reference
Inferring correlation networks from genomic survey data
10.1371/journal.pcbi.1002687 · 2012 · External reference
FastSpar: rapid and scalable correlation estimation for compositional data
10.1093/bioinformatics/bty734 · 2019 · External reference
Diet-quality scores and plasma concentrations of markers of inflammation and endothelial dysfunction
10.1093/ajcn/82.1.163 · 2005 · External reference
Healthful and Unhealthful Plant-Based Diets and the Risk of Coronary Heart Disease in U.S. Adults
10.1016/j.jacc.2017.05.047 · 2017 · External reference
