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References from Biological pathways and networks implicated in psychiatric disorders. Local targets link to admitted publications; unresolved targets remain external evidence.
The burden of mental disorders
10.1093/epirev/mxn011 · 2008 · External reference
Psychiatric epidemiology: reducing the global burden of mental illness
10.1093/aje/kwn298 · 2008 · External reference
A review and meta-analysis of the genetic epidemiology of anxiety disorders
10.1176/appi.ajp.158.10.1568 · 2001 · External reference
Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies
10.1001/archpsyc.60.12.1187 · 2003 · External reference
Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study
10.1016/s0140-6736(09)60072-6 · 2009 · External reference
Genetic heritability and shared environmental factors among twin pairs with autism
10.1001/archgenpsychiatry.2011.76 · 2011 · External reference
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
10.1038/ng.2711 · 2013 · External reference
Genetic architectures of psychiatric disorders: the emerging picture and its implications
10.1038/nrg3240 · 2012 · External reference
Medicine. The future of psychiatric research: genomes and neural circuits
10.1126/science.1188654 · 2010 · External reference
Five years of GWAS discovery
10.1016/j.ajhg.2011.11.029 · 2012 · External reference
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
10.1038/nature08185 · 2009 · External reference
De novo mutations in schizophrenia implicate synaptic networks
10.1038/nature12929 · 2014 · External reference
Interpreting the role of de novo protein-coding mutations in neuropsychiatric disease
10.1038/ng.2555 · 2013 · External reference
De novo mutations in human genetic disease
10.1038/nrg3241 · 2012 · External reference
The autism sequencing consortium: large-scale, high-throughput sequencing in autism spectrum disorders
10.1016/j.neuron.2012.12.008 · 2012 · External reference
Where GWAS and epidemiology meet: opportunities for the simultaneous study of genetic and environmental risk factors in schizophrenia
10.1093/schbul/sbt108 · 2013 · External reference
Biological insights from 108 schizophrenia-associated genetic loci
10.1038/nature13595 · 2014 · External reference
Initial impact of the sequencing of the human genome
10.1038/nature09792 · 2011 · External reference
Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis
10.1038/ng.2232 · 2012 · External reference
Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis
10.1038/ng.2609 · 2013 · External reference
A genome-wide association meta-analysis identifies new childhood obesity loci
10.1038/ng.2247 · 2012 · External reference
Hundreds of variants clustered in genomic loci and biological pathways affect human height
10.1038/nature09410 · 2010 · External reference
Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia
10.1038/ng.2652 · 2013 · External reference
Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization
10.1038/ng.2694 · 2013 · External reference
Analysing biological pathways in genome-wide association studies
10.1038/nrg2884 · 2010 · External reference
Genome-wide association analysis identifies 13 new risk loci for schizophrenia
10.1038/ng.2742 · 2013 · External reference
Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia
10.1038/mp.2011.117 · 2012 · External reference
Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility
10.1038/mp.2010.7 · 2011 · External reference
Specific glial functions contribute to schizophrenia susceptibility
10.1093/schbul/sbt109 · 2013 · External reference
Pathway analyses implicate glial cells in schizophrenia
10.1371/journal.pone.0089441 · 2014 · External reference
A hypothesis-driven pathway analysis reveals myelin-related pathways that contribute to the risk of schizophrenia and bipolar disorder
10.1016/j.pnpbp.2014.01.006 · 2014 · External reference
De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia
10.1038/mp.2011.154 · 2012 · External reference
Copy number variation in schizophrenia in Sweden
10.1038/mp.2014.40 · 2014 · External reference
A polygenic burden of rare disruptive mutations in schizophrenia
10.1038/nature12975 · 2014 · External reference
A noise-reduction GWAS analysis implicates altered regulation of neurite outgrowth and guidance in autism
10.1186/2040-2392-2-1 · 2011 · External reference
A discovery resource of rare copy number variations in individuals with autism spectrum disorder
10.1534/g3.112.004689 · 2012 · External reference
Identification of small exonic CNV from whole-exome sequence data and application to autism spectrum disorder
10.1016/j.ajhg.2013.09.001 · 2013 · External reference
Functional impact of global rare copy number variation in autism spectrum disorders
10.1038/nature09146 · 2010 · External reference
Biological overlap of attention-deficit/hyperactivity disorder and autism spectrum disorder: evidence from copy number variants
10.1016/j.jaac.2014.03.004 · 2014 · External reference
Convergence of genes and cellular pathways dysregulated in autism spectrum disorders
10.1016/j.ajhg.2014.03.018 · 2014 · External reference
Towards a molecular characterization of autism spectrum disorders: an exome sequencing and systems approach
10.1038/tp.2014.38 · 2014 · External reference
Patterns and rates of exonic de novo mutations in autism spectrum disorders
10.1038/nature11011 · 2012 · External reference
Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations
10.1038/nature10989 · 2012 · External reference
De novo mutations revealed by whole-exome sequencing are strongly associated with autism
10.1038/nature10945 · 2012 · External reference
De novo gene disruptions in children on the autistic spectrum
10.1016/j.neuron.2012.04.009 · 2012 · External reference
Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism
10.1016/j.cell.2013.10.031 · 2013 · External reference
Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism
10.1016/j.cell.2013.10.020 · 2013 · External reference
Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1
10.1186/1471-2350-15-2 · 2014 · External reference
Pathway analysis using information from allele-specific gene methylation in genome-wide association studies for bipolar disorder
10.1371/journal.pone.0053092 · 2013 · External reference
Epistasis network centrality analysis yields pathway replication across two GWAS cohorts for bipolar disorder
10.1038/tp.2012.80 · 2012 · External reference
Pathway analysis of seven common diseases assessed by genome-wide association
10.1016/j.ygeno.2008.07.011 · 2008 · External reference
Identification of pathways for bipolar disorder: a meta-analysis
10.1001/jamapsychiatry.2014.176 · 2014 · External reference
Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder
10.1016/j.ajhg.2009.05.011 · 2009 · External reference
Incorporating information of microRNAs into pathway analysis in a genome-wide association study of bipolar disorder
10.3389/fgene.2012.00293 · 2012 · External reference
Common genetic variants and gene-expression changes associated with bipolar disorder are over-represented in brain signaling pathway genes
10.1016/j.biopsych.2011.12.031 · 2012 · External reference
Convergent functional genomics of genome-wide association data for bipolar disorder: comprehensive identification of candidate genes, pathways and mechanisms
10.1002/ajmg.b.30887 · 2009 · External reference
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4
10.1038/ng.943 · 2011 · External reference
Rare copy number variation in treatment-resistant major depressive disorder
10.1016/j.biopsych.2013.10.028 · 2014 · External reference
A comprehensive network and pathway analysis of candidate genes in major depressive disorder
10.1186/1752-0509-5-s3-s12 · 2011 · External reference
Enriched pathways for major depressive disorder identified from a genome-wide association study
10.1017/s1461145711001891 · 2012 · External reference
Genome-wide pathway analysis in major depressive disorder
10.1007/s12031-013-0047-z · 2013 · External reference
Genome-wide pathway analysis in attention-deficit/hyperactivity disorder
10.1007/s10072-014-1671-2 · 2014 · External reference
Polygenic transmission and complex neuro developmental network for attention deficit hyperactivity disorder: genome-wide association study of both common and rare variants
10.1002/ajmg.b.32169 · 2013 · External reference
Investigating the contribution of common genetic variants to the risk and pathogenesis of ADHD
10.1176/appi.ajp.2011.11040551 · 2012 · External reference
Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits
10.1093/bioinformatics/19.1.149 · 2003 · External reference
Pathway-based approaches for analysis of genomewide association studies
10.1086/522374 · 2007 · External reference
Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology
10.1371/journal.pgen.1001273 · 2011 · External reference
Network properties of genes harboring inherited disease mutations
10.1073/pnas.0701722105 · 2008 · External reference
Functional gene group analysis reveals a role of synaptic heterotrimeric G proteins in cognitive ability
10.1016/j.ajhg.2009.12.006 · 2010 · External reference
An association screen of myelin-related genes implicates the chromosome 22q11 PIK4CA gene in schizophrenia
10.1038/sj.mp.4002080 · 2008 · External reference
Neurodevelopmental and neuropsychiatric disorders represent an interconnected molecular system
10.1038/mp.2013.16 · 2014 · External reference
FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism
10.1016/j.cell.2011.06.013 · 2011 · External reference
ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks
10.1093/bioinformatics/btp101 · 2009 · External reference
DADA: Degree-Aware Algorithms for Network-Based Disease Gene Prioritization
10.1186/1756-0381-4-19 · 2011 · External reference
DAVID: Database for Annotation, Visualization, and Integrated Discovery
10.1186/gb-2003-4-5-p3 · 2003 · External reference
Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool
10.1186/1471-2105-14-128 · 2013 · External reference
Boosting signal-to-noise in complex biology: prior knowledge is power
10.1016/j.cell.2011.03.007 · 2011 · External reference
The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function
10.1093/nar/gkq537 · 2010 · External reference
GREAT improves functional interpretation of cis-regulatory regions
10.1038/nbt.1630 · 2010 · External reference
ICSNPathway: identify candidate causal SNPs and pathways from genome-wide association study by one analytical framework
10.1093/nar/gkr391 · 2011 · External reference
INRICH: interval-based enrichment analysis for genome-wide association studies
10.1093/bioinformatics/bts191 · 2012 · External reference
The IntAct molecular interaction database in 2010
10.1093/nar/gkp878 · 2010 · External reference
Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits
10.1371/journal.pgen.1001058 · 2010 · External reference
Power to detect risk alleles using genome-wide tag SNP panels
10.1371/journal.pgen.0030170 · 2007 · External reference
MINT, the molecular interaction database: 2009 update
10.1093/nar/gkp983 · 2010 · External reference
The BioGRID Interaction Database: 2011 update
10.1093/nar/gkq1116 · 2011 · External reference
The SNP ratio test: pathway analysis of genome-wide association datasets
10.1093/bioinformatics/btp448 · 2009 · External reference
Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function
10.1371/journal.pgen.1001097 · 2010 · External reference
HYST: a hybrid set-based test for genome-wide association studies, with application to protein–protein interaction-based association analysis
10.1016/j.ajhg.2012.08.004 · 2012 · External reference
WebGestalt: an integrated system for exploring gene sets in various biological contexts
10.1093/nar/gki475 · 2005 · External reference