Research graph
References from Extracellular vesicle-like particles derived from Epimedium sagittatum activate mitophagy to counteract senescence and alleviate postmenopausal osteoporosis. Local targets link to admitted publications; unresolved targets remain external evidence.
Novel plant-derived exosome-like nanovesicles from Catharanthus roseus: preparation, characterization, and immunostimulatory effect via TNF-α/NF-κB/PU.1 axis
10.1186/s12951-023-01919-x · 2023 · External reference
Plant-derived vesicle-like nanoparticles as promising biotherapeutic tools: present and future
10.1002/adma.202207826 · 2023 · External reference
Plant-derived exosomes: unveiling the similarities and disparities between conventional extract and innovative form
10.1016/j.phymed.2025.157087 · 2025 · External reference
Broccoli-derived nanoparticle inhibits mouse colitis by activating dendritic cell AMP-activated protein kinase
10.1016/j.ymthe.2017.01.025 · 2017 · External reference
Lemon exosome-like nanoparticles enhance stress survival of gut bacteria by RNase P-mediated specific tRNA decay
10.1016/j.isci.2021.102511 · 2021 · External reference
Ginseng-derived nanoparticles alter macrophage polarization to inhibit melanoma growth
10.1186/s40425-019-0817-4 · 2019 · External reference
Targeted drug delivery to intestinal macrophages by bioactive nanovesicles released from grapefruit
10.1038/mt.2013.190 · 2014 · External reference
Icaritin inhibits osteoclast differentiation and reduces bone loss by targeting ESR1 to inhibit miR503/RANK pathway
2025 · External reference
Epimedium brevicornu Maxim.-derived extracellular vesicle-like particles stimulate VEGF-mediated angiogenesis to alleviate postmenopausal osteoporosis
2025 · External reference
Osteoporosis remission via an anti-inflammaging effect by icariin activated autophagy
2023 · External reference
The therapeutic potential of icariin in the intervention of bone and joint diseases through multiple pathways: a narrative review
10.3389/fphar.2025.1606912 · 2025 · External reference
Osteoporosis
10.1016/s0140-6736(25)01385-6 · 2025 · External reference
Rejuvenation of mesenchymal stem cells to ameliorate skeletal aging
10.3390/cells12070998 · 2023 · External reference
10.1186/s13287-025-04874-6
10.1186/s13287-025-04874-6 · External reference
The relationship between bone marrow adipose tissue and bone metabolism in postmenopausal osteoporosis
10.1016/j.cytogfr.2020.02.003 · 2020 · External reference
Mitochondrial ROS drive adipogenic differentiation in osteoporosis by suppressing protein synthesis
10.1096/fj.202502869r · 2025 · External reference
Insights into ionic medicine: cerium reduces the presence of reactive oxygen species and favors osteogenic over adipogenic differentiation in human mesenchymal stromal cells
10.1016/j.jtemb.2025.127668 · 2025 · External reference
Enhanced osseointegration of three-dimensional supramolecular bioactive interface through osteoporotic microenvironment regulation
10.7150/thno.43736 · 2020 · External reference
A multifunctional composite hydrogel that rescues the ROS microenvironment and guides the immune response for repair of osteoporotic bone defects
2022 · External reference
Acid neutralization and immune regulation by calcium–aluminum-layered double hydroxide for osteoporosis reversion
10.1021/jacs.2c00749 · 2022 · External reference
A bone-targeted engineered exosome platform delivering siRNA to treat osteoporosis
2021 · External reference
Construction of wogonin nanoparticle-containing strontium-doped nanoporous structure on titanium surface to promote osteoporosis fracture repair
10.1002/adhm.202201405 · 2022 · External reference
Copper-incorporated bioactive glass-ceramics inducing anti-inflammatory phenotype and regeneration of cartilage/bone interface
10.7150/thno.36120 · 2019 · External reference
Afzelin ameliorates D-galactosamine and lipopolysaccharide-induced fulminant hepatic failure by modulating mitochondrial quality control and dynamics
10.1111/bph.13669 · 2017 · External reference
Afzelin resists UVA damage through autophagy and synergizes with ganoderic acid A to skin photoaging
10.1016/j.phymed.2026.157782 · 2026 · External reference
Construction of wogonin nanoparticle-containing strontium-doped nanoporous structure on titanium surface to promote osteoporosis fracture repair
10.1002/adhm.202201405 · ExternalCitation · doi-reference
Plant-derived vesicle-like nanoparticles as promising biotherapeutic tools: present and future
10.1002/adma.202207826 · ExternalCitation · doi-reference
The relationship between bone marrow adipose tissue and bone metabolism in postmenopausal osteoporosis
10.1016/j.cytogfr.2020.02.003 · ExternalCitation · doi-reference
Lemon exosome-like nanoparticles enhance stress survival of gut bacteria by RNase P-mediated specific tRNA decay
10.1016/j.isci.2021.102511 · ExternalCitation · doi-reference
Insights into ionic medicine: cerium reduces the presence of reactive oxygen species and favors osteogenic over adipogenic differentiation in human mesenchymal stromal cells
10.1016/j.jtemb.2025.127668 · ExternalCitation · doi-reference
Plant-derived exosomes: unveiling the similarities and disparities between conventional extract and innovative form
10.1016/j.phymed.2025.157087 · ExternalCitation · doi-reference
Afzelin resists UVA damage through autophagy and synergizes with ganoderic acid A to skin photoaging
10.1016/j.phymed.2026.157782 · ExternalCitation · doi-reference
Broccoli-derived nanoparticle inhibits mouse colitis by activating dendritic cell AMP-activated protein kinase
10.1016/j.ymthe.2017.01.025 · ExternalCitation · doi-reference
Osteoporosis
10.1016/s0140-6736(25)01385-6 · ExternalCitation · doi-reference
Acid neutralization and immune regulation by calcium–aluminum-layered double hydroxide for osteoporosis reversion
10.1021/jacs.2c00749 · ExternalCitation · doi-reference
Targeted drug delivery to intestinal macrophages by bioactive nanovesicles released from grapefruit
10.1038/mt.2013.190 · ExternalCitation · doi-reference
Mitochondrial ROS drive adipogenic differentiation in osteoporosis by suppressing protein synthesis
10.1096/fj.202502869r · ExternalCitation · doi-reference
Afzelin ameliorates D-galactosamine and lipopolysaccharide-induced fulminant hepatic failure by modulating mitochondrial quality control and dynamics
10.1111/bph.13669 · ExternalCitation · doi-reference
Novel plant-derived exosome-like nanovesicles from Catharanthus roseus: preparation, characterization, and immunostimulatory effect via TNF-α/NF-κB/PU.1 axis
10.1186/s12951-023-01919-x · ExternalCitation · doi-reference
10.1186/s13287-025-04874-6
10.1186/s13287-025-04874-6 · ExternalCitation · doi-reference
Ginseng-derived nanoparticles alter macrophage polarization to inhibit melanoma growth
10.1186/s40425-019-0817-4 · ExternalCitation · doi-reference
The therapeutic potential of icariin in the intervention of bone and joint diseases through multiple pathways: a narrative review
10.3389/fphar.2025.1606912 · ExternalCitation · doi-reference
Rejuvenation of mesenchymal stem cells to ameliorate skeletal aging
10.3390/cells12070998 · ExternalCitation · doi-reference
Copper-incorporated bioactive glass-ceramics inducing anti-inflammatory phenotype and regeneration of cartilage/bone interface
10.7150/thno.36120 · ExternalCitation · doi-reference
Enhanced osseointegration of three-dimensional supramolecular bioactive interface through osteoporotic microenvironment regulation
10.7150/thno.43736 · ExternalCitation · doi-reference
