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References from Engineered polymeric nanosponge in-situ gel enables sustained and enhanced nose-to-brain delivery of quetiapine fumarate. Local targets link to admitted publications; unresolved targets remain external evidence.
What is the risk-benefit ratio of long-term antipsychotic treatment in people with schizophrenia?
10.1002/wps.20516 · 2018 · External reference
Re-evaluating the prognosis of schizophrenia: tackling the issue of inadequate treatment
10.1080/14737175.2024.2365943 · 2024 · External reference
Medication adherence in schizophrenia: factors influencing adherence and consequences of nonadherence, a systematic literature review
10.1177/2045125312474019 · 2013 · External reference
Medicinal chemistry based approaches and nanotechnology-based systems to improve CNS drug targeting and delivery
10.1002/med.21252 · 2013 · External reference
Advancements in Using Polymeric Nanoparticles for Blood–Brain Barrier Penetration in Neurological Disorders
10.1021/acsabm.4c01956 · 2025 · External reference
Effectiveness of second-generation antipsychotics: a naturalistic, randomized comparison of olanzapine, quetiapine, risperidone, and ziprasidone
10.1186/1471-244x-10-26 · 2010 · External reference
Preparation, characterization and evaluation of quetiapine fumarate solid lipid nanoparticles to improve the oral bioavailability
2013 · External reference
Cardiac adverse events associated with quetiapine: disproportionality analysis of FDA adverse event reporting system
10.1111/cns.14215 · 2023 · External reference
Quetiapine fumarate overdose: clinical and pharmacokinetic lessons from extreme conditions
10.1067/mcp.2000.107507 · 2000 · External reference
Intranasal drug delivery technology in the treatment of central nervous system diseases: challenges, advances, and future research directions
10.3390/pharmaceutics17060775 · 2025 · External reference
The nasal mucociliary clearance: relevance to nasal drug delivery
10.1023/a:1015830907632 · 1991 · External reference
Drug delivery and targeting to the brain through nasal route: mechanisms, applications and challenges
10.2174/1567201816666191029122740 · 2019 · External reference
The ascension of nanosponges as a drug delivery carrier: preparation, characterization, and applications
10.1007/s10856-022-06652-9 · 2022 · External reference
Nanosponges for drug delivery and cancer therapy: Recent advances
10.3390/nano12142440 · 2022 · External reference
In situ gels for nasal delivery: Formulation, characterization and applications
10.1002/mame.202400356 · 2025 · External reference
A Nanoemulgel for Nose-to-Brain delivery of Quetiapine–QbD-Enabled formulation development & in-vitro characterization
10.1016/j.ijpharm.2023.123566 · 2023 · External reference
Plackett-Burman design for screening of critical variables and their effects on the optical transparency and swelling of gatifloxacin-Pluronic-loaded contact lens
10.1016/j.ijpharm.2019.06.008 · 2019 · External reference
QBD approach for the development of hesperetin loaded colloidal nanosponges for sustained delivery: In-vitro, ex-vivo, and in-vivo assessment
10.1016/j.onano.2022.100045 · 2022 · External reference
An overview of mucoadhesive thermoreversible nasal gel
2021 · External reference
Formulation and in vitro evaluation of topical nanosponge-based gel containing butenafine for the treatment of fungal skin infection
10.1016/j.jsps.2021.04.010 · 2021 · External reference
Formulation and development of posaconazole loaded controlled release nanosponge topical gel for the treatment of fungal infection
10.1007/s12247-024-09912-z · 2025 · External reference
Fabrication, characterization, and docking studies of furosemide-loaded nanosponges using the emulsion solvent diffusion method
10.1080/17435889.2025.2501518 · 2025 · External reference
Design and optimization of curcumin loaded nano lipid carrier system using Box-Behnken design
10.1016/j.biopha.2021.111919 · 2021 · External reference
Multiple response optimisation of processing and formulation parameters of pH sensitive sustained release pellets of capecitabine for targeting colon
10.1080/02652048.2018.1465138 · 2018 · External reference
Formulation and optimization of transferrin-modified genistein nanocrystals: In vitro anti-cancer assessment and pharmacokinetic evaluation
10.1016/j.ijpharm.2024.124863 · 2024 · External reference
Formulation and evaluation of clindamycin HCL in situ gel for vaginal application
10.4103/2230-973x.147233 · 2015 · External reference
Formulation and evaluation of gliclazide nanosponges
10.22159/ijap.2019v11i6.35006 · 2019 · External reference
Tailored doxycycline hyclate loaded in situ gel for the treatment of periodontitis: Optimization, in vitro characterization, and antimicrobial studies
10.1208/s12249-021-01950-x · 2021 · External reference
A 3 2 full factorial design for development and characterization of a nanosponge-based intravaginal in situ gelling system for vulvovaginal candidiasis
10.1039/c5ra26218f · 2016 · External reference
Development and evaluation of hydrogel-based sulfasalazine-loaded nanosponges for enhanced topical psoriasis therapy
10.3390/ph18030391 · 2025 · External reference
Development of a Gellan–Carbopol in Situ Gel System for Intranasal Delivery of Artemether-Loaded SLNs: Optimization and Kinetic Evaluation
10.1007/s12247-025-10263-6 · 2026 · External reference
Formulation and evaluation of thermoreversible, mucoadhesive in situ intranasal gel of rizatriptan benzoate
10.1007/s10971-014-3422-5 · 2014 · External reference
Intranasal delivery of doxepin: enhancing brain targeting efficiency utilizing nanostructured lipid carriers for a biopharmaceutics drug disposition classification system class-I drug
10.1080/10837450.2024.2376102 · 2024 · External reference
Clozapine-laden carbon dots delivered to the brain via an intranasal pathway: Synthesis, characterization, ex vivo, and in vivo studies
10.1016/j.colsurfb.2024.113862 · 2024 · External reference
Unresolved reference
External reference
Intranasal nano-delivery systems: emerging strategies for central nervous system disease therapeutics
2026 · External reference
Development and evaluation of scaffold-based nanosponge formulation for controlled drug delivery of naproxen and ibuprofen
10.4314/tjpr.v17i8.2 · 2018 · External reference
Development and evaluation of polymeric nanosponge hydrogel for terbinafine hydrochloride: statistical optimization, in vitro and in vivo studies
2020 · External reference
Microsponge based gel as a simple and valuable strategy for formulating and releasing Tazarotene in a controlled manner
10.1038/s41598-022-15655-z · 2022 · External reference
Optimisation of a greener-approach for the synthesis of cyclodextrin-based nanosponges for the solubility enhancement of domperidone, a BCS class II drug
10.3390/ph16040567 · 2023 · External reference
Ethyl-cellulose nanosponges for topical delivery of simvastatin with preferential skin retention for wound healing in a full-thickness wound rat model
10.1208/s12249-025-03114-7 · 2025 · External reference
Development and Invitro Characterization of Nanosponge Formulation of Lovastatin for Oral Delivery Using a Central Composite Design
2025 · External reference
Screening of adapalene microsponges fabrication parameters with insight on the in vitro biological effectiveness
10.2147/dddt.s383051 · 2022 · External reference
Revolutionizing Drug Delivery: The Impact of Microsponges in Pharmaceutical Research
10.2174/0122103031308362240806113226 · 2025 · External reference
Preparation of posaconazole nanosponges for improved topical delivery system
10.25258/ijddt.12.1.2 · 2022 · External reference
The effect of formulation and process variables on prepared etoricoxib Nanosponges
10.51847/q0qrkuv2kq · 2021 · External reference
Development of abemaciclib-encapsulated nanosponges for breast cancer: optimization, drug release kinetics, and in vitro efficacy
10.69857/joapr.v13i4.1234 · 2025 · External reference
Receptor occupancy and brain free fraction
10.1124/dmd.108.022814 · 2009 · External reference
A positron emission tomography study of quetiapine in schizophrenia: a preliminary finding of an antipsychotic effect with only transiently high dopamine D2 receptor occupancy
10.1001/archpsyc.57.6.553 · 2000 · External reference