Research graph
References from Integrative multi-omics analysis reveals UBE2C as a potential prognostic biomarker and therapeutic target of breast cancer. Local targets link to admitted publications; unresolved targets remain external evidence.
Treatment landscape of triple-negative breast cancer - expanded options, evolving needs
10.1038/s41571-021-00565-2 · 2022 · External reference
UALCAN: An update to the integrated cancer data analysis platform
10.1016/j.neo.2022.01.001 · 2022 · External reference
Atomic structure of the APC/C and its mechanism of protein ubiquitination
10.1038/nature14471 · 2015 · External reference
Ubiquitination in the regulation of inflammatory cell death and cancer
10.1038/s41418-020-00708-5 · 2021 · External reference
Prospective role and immunotherapeutic targets of sideroflexin protein family in lung adenocarcinoma: evidence from bioinformatics validation
10.1007/s10142-022-00883-3 · 2022 · External reference
FOXM1 in Cancer: Interactions and Vulnerabilities
10.1158/0008-5472.can-16-3566 · 2017 · External reference
Integrated analysis of public datasets for the discovery and validation of survival-associated genes in solid tumors
2024 · External reference
Breast cancer
10.1038/s41572-019-0111-2 · 2019 · External reference
FOXM1 promotes hepatocellular carcinoma progression by regulating KIF4A expression
10.1186/s13046-019-1202-3 · 2019 · External reference
FOXM1: A small fox that makes more tracks for cancer progression and metastasis
10.1016/j.semcancer.2023.03.007 · 2023 · External reference
The Human Transcription Factors
10.1016/j.cell.2018.01.029 · 2018 · External reference
TIMER2.0 for analysis of tumor-infiltrating immune cells
10.1093/nar/gkaa407 · 2020 · External reference
UBE2C-induced crosstalk between mono- and polyubiquitination of SNAT2 promotes lymphatic metastasis in bladder cancer
10.1172/jci179122 · 2024 · External reference
Receiver operating characteristic curve in diagnostic test assessment
10.1097/jto.0b013e3181ec173d · 2010 · External reference
Ubiquitin chain-elongating enzyme UBE2S activates the RING E3 ligase APC/C for substrate priming
10.1038/s41594-020-0424-6 · 2020 · External reference
Intratumor Heterogeneity: The Rosetta Stone of Therapy Resistance
10.1016/j.ccell.2020.03.007 · 2020 · External reference
Small-molecule inhibitors targeting FOXM1: Current challenges and future perspectives in cancer treatments
10.1016/j.bbcan.2023.189015 · 2023 · External reference
Dysregulated FOXM1 signaling in the regulation of cancer stem cells
10.1016/j.semcancer.2022.07.009 · 2022 · External reference
Spatiotemporal regulation of the anaphase-promoting complex in mitosis
10.1038/nrm3934 · 2015 · External reference
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
2021 · External reference
GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis
10.1093/nar/gkz430 · 2019 · External reference
GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses
10.1093/nar/gkx247 · 2017 · External reference
Hyper-methylation of ABCG1 as an epigenetics biomarker in non-small cell lung cancer
10.1007/s10142-023-01185-y · 2023 · External reference
Proteomics. Tissue-based map of the human proteome
10.1126/science.1260419 · 2015 · External reference
A pathology atlas of the human cancer transcriptome
10.1126/science.aan2507 · 2017 · External reference
Inhibition of UBE2C Promotes Parkin-Mediated K63-Linked Ubiquitination of TOP2A to Induce Senescence and Increase Sensitivity of Doxorubicin in Breast Cancer
2025 · External reference
CancerSEA: a cancer single-cell state atlas
10.1093/nar/gky939 · 2019 · External reference
The UBE2C/CDH1/DEPTOR axis is an oncogene and tumor suppressor cascade in lung cancer cells
10.1172/jci162434 · 2023 · External reference
FoxM1 promotes the migration of ovarian cancer cell through KRT5 and KRT7
10.1016/j.gene.2020.144947 · 2020 · External reference
