Research graph
References from Integrative multi-omics analysis reveals the PFAS-gut microbiome-FN1 axis in chronic kidney disease: From exposome to therapeutic target. Local targets link to admitted publications; unresolved targets remain external evidence.
The gut-kidney axis in chronic kidney disease: mechanisms, microbial metabolites, and microbiome-targeted therapeutics
10.3389/fmed.2025.1675458 · 2025 · External reference
Interferon-alpha and -beta in kidney inflammation
10.1038/ki.2010.71 · 2010 · External reference
The protein data bank
10.1093/nar/28.1.235 · 2000 · External reference
Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression
10.1093/ije/dyv080 · 2015 · External reference
Perfluoroalkyl and polyfluoroalkyl substances in the environment: terminology, classification, and origins
10.1002/ieam.258 · 2011 · External reference
Mendelian randomization analysis with multiple genetic variants using summarized data
10.1002/gepi.21758 · 2013 · External reference
Serum concentrations of 11 polyfluoroalkyl compounds in the U.S. population: data from NHANES 1999–2000
10.1021/es062686m · 2007 · External reference
Human gut microbiome: hopes, threats and promises
10.1136/gutjnl-2018-316723 · 2018 · External reference
Association of perfluoroalkyl and polyfluoroalkyl substances with kidney function and chronic kidney disease: the Gen3G study
2023 · External reference
JASPAR 2022: the 9th release of the open-access database of transcription factor binding profiles
10.1093/nar/gkab1113 · 2022 · External reference
Perfluoroalkyl substances and gut microbiome in children
2023 · External reference
Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study
10.1038/s41591-019-0495-2 · 2019 · External reference
Molecular dynamics simulations and drug discovery
10.1186/1741-7007-9-71 · 2011 · External reference
OpenMM 7: rapid development of high performance algorithms for molecular dynamics
10.1371/journal.pcbi.1005659 · 2017 · External reference
AutoDock Vina 1.2.0: new docking methods, expanded force field, and Python bindings
10.1021/acs.jcim.1c00203 · 2021 · External reference
gseapy: a comprehensive package for performing gene set enrichment analysis in Python
10.1093/bioinformatics/btac757 · 2023 · External reference
Adopting mechanistic molecular biology approaches in exposome research for causal understanding
10.1021/acs.est.3c07961 · 2024 · External reference
Integrating multi-omics with environmental data for precision health
2024 · External reference
The potential mediating role of the gut microbiome and metabolites in the association between PFAS and kidney function in young adults
2024 · External reference
Robust inference in summary data Mendelian randomization via the zero modal pleiotropy assumption
10.1093/ije/dyx102 · 2017 · External reference
Association of combined per- and polyfluoroalkyl substances and metals with chronic kidney disease: NHANES 2013–2018
10.3390/ijerph21040468 · 2024 · External reference
Mechanisms of renal fibrosis
10.1146/annurev-physiol-022516-034227 · 2018 · External reference
Bile acids and farnesoid X receptor in renal pathophysiology
2024 · External reference
Proteomic landscape of the extracellular matrix in the fibrotic kidney
10.1016/j.kint.2023.01.021 · 2023 · External reference
Akkermansia muciniphila for the prevention of type 2 diabetes and obesity: a meta-analysis of animal studies
10.3390/nu16203440 · 2024 · External reference
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
10.1038/nm.3902 · 2015 · External reference
TGF-beta: the master regulator of fibrosis
10.1038/nrneph.2016.48 · 2016 · External reference
Fibronectin at a glance
10.1242/jcs.00059 · 2002 · External reference
Periostin in kidney diseases
10.1007/s00018-017-2650-6 · 2017 · External reference
Genetic evidence supporting the causal role of gut microbiota in chronic kidney disease and chronic systemic inflammation in CKD: a bilateral two-sample Mendelian randomization study
10.3389/fimmu.2023.1287698 · 2023 · External reference
Cytoscape: a software environment for integrated models of biomolecular interaction networks
10.1101/gr.1239303 · 2003 · External reference
Desulfovibrio in the gut: the enemy within?
10.3390/microorganisms11071772 · 2023 · External reference
Perfluorinated chemicals as emerging environmental threats to kidney health: a scoping review
10.2215/cjn.04670418 · 2018 · External reference
Perfluorooctanoic acid exposure induces gut microbiome dysbiosis and metabolic alterations in mice
2022 · External reference
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
10.1073/pnas.0506580102 · 2005 · External reference
Gut microbiota-targeted interventions in the management of chronic kidney disease
10.1016/j.semnephrol.2023.151408 · 2023 · External reference
A review of the pathways of human exposure to poly- and perfluoroalkyl substances (PFASs) and present understanding of health effects
10.1038/s41370-018-0094-1 · 2019 · External reference
The STRING database in 2023: protein-protein association networks and functional enrichment analyses for any sequenced genome of interest
10.1093/nar/gkac1000 · 2023 · External reference
The gut-kidney axis in chronic kidney diseases
10.3390/diagnostics15010021 · 2024 · External reference
Associations of per- and polyfluoroalkyl substances and mortality among individuals with chronic kidney disease: a retrospective cohort study
2024 · External reference
Constrained maximum likelihood-based Mendelian randomization robust to both correlated and uncorrelated pleiotropic effects
10.1016/j.ajhg.2021.05.014 · 2021 · External reference
Association between exposure to per- and polyfluoroalkyl substances and kidney function: a population study
2025 · External reference
Statistical inference in two-sample summary-data Mendelian randomization using robust adjusted profile score
10.1214/19-aos1866 · 2020 · External reference
Causal relationship between gut microbiota and kidney diseases: a two-sample Mendelian randomization study
2023 · External reference