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References from A systemic neuroendocrine immune axis in breast cancer revealed by MMD regularized cross tissue latent alignment across four independent cohorts. Local targets link to admitted publications; unresolved targets remain external evidence.
Hallmarks of cancer: the next generation
10.1016/j.cell.2011.02.013 · 2011 · External reference
New concepts in prolactin biology
10.1677/joe-10-0069 · 2010 · External reference
Abundant tumor infiltrating lymphocytes after primary systemic chemotherapy predicts poor prognosis in estrogen receptor-positive/HER2-negative breast cancers
10.1007/s10549-017-4575-z · 2018 · External reference
Correlates of circulating C-reactive protein and serum amyloid a concentrations in breast cancer survivors
10.1007/s10549-008-9985-5 · 2009 · External reference
Post-surgical highly sensitive C-reactive protein and prognosis in early-stage breast cancer
10.1007/s10549-013-2694-8 · 2013 · External reference
Single-cell profiling of breast cancer T cells reveals a tissue-resident memory subset associated with improved prognosis
10.1038/s41591-018-0078-7 · 2018 · External reference
The immune contexture in human tumours: impact on clinical outcome
10.1038/nrc3245 · 2012 · External reference
Atezolizumab and nab-paclitaxel in advanced triple-negative breast cancer
10.1056/nejmoa1809615 · 2018 · External reference
Tumour-infiltrating lymphocytes and prognosis in different subtypes of breast cancer: a pooled analysis of 3771 patients treated with neoadjuvant therapy
10.1016/s1470-2045(17)30904-x · 2018 · External reference
Autoimmune hypophysitis
10.1210/er.2004-0011 · 2005 · External reference
Pituitary expression of CTLA-4 mediates hypophysitis secondary to administration of CTLA-4 blocking antibody
10.1126/scitranslmed.3008002 · 2014 · External reference
Prolactin: a stimulator of disease activity in systemic lupus erythematosus
10.1177/096120339500400102 · 1995 · External reference
Prolactin in man: a tale of two promoters
10.1002/bies.20468 · 2006 · External reference
Acute-phase proteins and other systemic responses to inflammation
10.1056/nejm199902113400607 · 1999 · External reference
The GTEx consortium atlas of genetic regulatory effects across human tissues
10.1126/science.aaz1776 · 2020 · External reference
Comprehensive molecular portraits of human breast tumours
10.1038/nature11412 · 2012 · External reference
Benchmarking atlas-level data integration in single-cell genomics
10.1038/s41592-021-01336-8 · 2022 · External reference
A benchmark of batch-effect correction methods for single-cell RNA sequencing data
2020 · External reference
A kernel two-sample test
2012 · External reference
scGen predicts single-cell perturbation responses
10.1038/s41592-019-0494-8 · 2019 · External reference
scBERT as a large-scale pretrained deep language model for cell type annotation of single-cell RNA-seq data
10.1038/s42256-022-00534-z · 2022 · External reference
scMM: mixture-of-experts multimodal deep generative model for single-cell multiomics data analysis
2022 · External reference
Tumor immune microenvironment and immunosuppression
2019 · External reference
Checkpoint blockade in the treatment of breast cancer: current status and future directions
10.1038/s41416-018-0126-6 · 2018 · External reference
Understanding the tumor immune microenvironment (TIME) for effective therapy
10.1038/s41591-018-0014-x · 2018 · External reference
Biochemistry and physiology of mammalian secreted phospholipases A2
10.1146/annurev.biochem.76.062405.154007 · 2008 · External reference
Expanding roles of secreted phospholipase A2 in biological systems
10.3390/biom10101457 · 2020 · External reference
Dual roles of group IID secreted phospholipase A2 in inflammation and resolution
2013 · External reference
Group IID secreted phospholipase A2 regulates T-lymphocyte functions and eicosanoid production
2006 · External reference
Phospholipase A2 a mediator between proximal and distal effectors of inflammation
1991 · External reference
Structural properties of human phospholipase A2 that confer the capacity for acute-phase secretion
10.1016/s0021-9258(18)52293-6 · 1991 · External reference
The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation
10.1056/nejm199505183322008 · 1995 · External reference
Neuroendocrine regulation of autoimmune/inflammatory disease
10.1677/joe.0.1690429 · 2001 · External reference
Tackling the widespread and critical impact of batch effects in high-throughput data
10.1038/nrg2825 · 2010 · External reference
Adjusting batch effects in microarray expression data using empirical Bayes methods
10.1093/biostatistics/kxj037 · 2007 · External reference
limma powers differential expression analyses for RNA-sequencing and microarray studies
10.1093/nar/gkv007 · 2015 · External reference
Generative moment matching networks
2015 · External reference
Visualizing and interpreting cancer genomics data via the Xena platform
10.1038/s41587-020-0546-8 · 2020 · External reference
STAR: ultrafast universal RNA-seq aligner
10.1093/bioinformatics/bts635 · 2013 · External reference
Integrated analysis of multimodal single-cell data
10.1016/j.cell.2021.04.048 · 2021 · External reference
The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
10.1038/nature10983 · 2012 · External reference
The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data
10.1158/2159-8290.cd-12-0095 · 2012 · External reference
Clinical value of RNA sequencing-based classifiers for prediction of the five conventional breast cancer biomarkers: a report from the population-based multicenter Sweden cancerome analysis network – breast initiative
10.1200/po.17.00135 · 2018 · External reference
Batch normalization: accelerating deep network training by reducing internal covariate shift
2015 · External reference
PyTorch: an imperative style, high-performance deep learning library
2019 · External reference
Liquid biopsies come of age: towards implementation of circulating tumour DNA
10.1038/nrc.2017.7 · 2017 · External reference
Serum amyloid a: an acute-phase protein involved in tumour pathogenesis
10.1007/s00018-008-8321-x · 2009 · External reference
Old and new findings on lipopolysaccharide-binding protein: a soluble pattern-recognition molecule
10.1042/bst0390989 · 2011 · External reference
CXCL17 is a mucosal chemokine elevated in idiopathic pulmonary fibrosis that exhibits broad antimicrobial and immunomodulatory activity
10.4049/jimmunol.1102903 · 2012 · External reference
lifelines: survival analysis in Python
10.21105/joss.01317 · 2019 · External reference
Perturbation-response genes reveal signaling footprints in cancer gene expression
2018 · External reference
Neural-immune-cancer crosstalk in pancreatic cancer: mechanisms and clinical translation
2026 · External reference
Sensory neurons drive immune exclusion by stimulating a dense extracellular matrix in the breast cancer tumor microenvironment
2026 · External reference
Neuro-immune crosstalk in breast cancer: molecular mechanisms from stress signals to immune escape
10.3389/fimmu.2026.1790195 · 2026 · External reference
The association between the neuroendocrine system and the tumor immune microenvironment: emerging directions for cancer immunotherapy
2023 · External reference
Mechanism-informed machine learning enables discovery of oncolytic peptides for cancer immunotherapy
2026 · External reference
Targeting the neuro-immune crosstalk in breast cancer brain metastases
10.1136/jitc-2025-014134 · 2026 · External reference
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
10.1073/pnas.0506580102 · 2005 · External reference
Prolactin in man: a tale of two promoters
10.1002/bies.20468 · ExternalCitation · doi-reference
Serum amyloid a: an acute-phase protein involved in tumour pathogenesis
10.1007/s00018-008-8321-x · ExternalCitation · doi-reference
Correlates of circulating C-reactive protein and serum amyloid a concentrations in breast cancer survivors
10.1007/s10549-008-9985-5 · ExternalCitation · doi-reference
Post-surgical highly sensitive C-reactive protein and prognosis in early-stage breast cancer
10.1007/s10549-013-2694-8 · ExternalCitation · doi-reference
Abundant tumor infiltrating lymphocytes after primary systemic chemotherapy predicts poor prognosis in estrogen receptor-positive/HER2-negative breast cancers
10.1007/s10549-017-4575-z · ExternalCitation · doi-reference
Hallmarks of cancer: the next generation
10.1016/j.cell.2011.02.013 · ExternalCitation · doi-reference
Integrated analysis of multimodal single-cell data
10.1016/j.cell.2021.04.048 · ExternalCitation · doi-reference
Structural properties of human phospholipase A2 that confer the capacity for acute-phase secretion
10.1016/s0021-9258(18)52293-6 · ExternalCitation · doi-reference
Tumour-infiltrating lymphocytes and prognosis in different subtypes of breast cancer: a pooled analysis of 3771 patients treated with neoadjuvant therapy
10.1016/s1470-2045(17)30904-x · ExternalCitation · doi-reference
The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
10.1038/nature10983 · ExternalCitation · doi-reference
Comprehensive molecular portraits of human breast tumours
10.1038/nature11412 · ExternalCitation · doi-reference
Liquid biopsies come of age: towards implementation of circulating tumour DNA
10.1038/nrc.2017.7 · ExternalCitation · doi-reference
The immune contexture in human tumours: impact on clinical outcome
10.1038/nrc3245 · ExternalCitation · doi-reference
Tackling the widespread and critical impact of batch effects in high-throughput data
10.1038/nrg2825 · ExternalCitation · doi-reference
Checkpoint blockade in the treatment of breast cancer: current status and future directions
10.1038/s41416-018-0126-6 · ExternalCitation · doi-reference
Visualizing and interpreting cancer genomics data via the Xena platform
10.1038/s41587-020-0546-8 · ExternalCitation · doi-reference
Understanding the tumor immune microenvironment (TIME) for effective therapy
10.1038/s41591-018-0014-x · ExternalCitation · doi-reference
Single-cell profiling of breast cancer T cells reveals a tissue-resident memory subset associated with improved prognosis
10.1038/s41591-018-0078-7 · ExternalCitation · doi-reference
scGen predicts single-cell perturbation responses
10.1038/s41592-019-0494-8 · ExternalCitation · doi-reference
Benchmarking atlas-level data integration in single-cell genomics
10.1038/s41592-021-01336-8 · ExternalCitation · doi-reference
scBERT as a large-scale pretrained deep language model for cell type annotation of single-cell RNA-seq data
10.1038/s42256-022-00534-z · ExternalCitation · doi-reference
Old and new findings on lipopolysaccharide-binding protein: a soluble pattern-recognition molecule
10.1042/bst0390989 · ExternalCitation · doi-reference
The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation
10.1056/nejm199505183322008 · ExternalCitation · doi-reference
Acute-phase proteins and other systemic responses to inflammation
10.1056/nejm199902113400607 · ExternalCitation · doi-reference
Atezolizumab and nab-paclitaxel in advanced triple-negative breast cancer
10.1056/nejmoa1809615 · ExternalCitation · doi-reference
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
10.1073/pnas.0506580102 · ExternalCitation · doi-reference
STAR: ultrafast universal RNA-seq aligner
10.1093/bioinformatics/bts635 · ExternalCitation · doi-reference
Adjusting batch effects in microarray expression data using empirical Bayes methods
10.1093/biostatistics/kxj037 · ExternalCitation · doi-reference
limma powers differential expression analyses for RNA-sequencing and microarray studies
10.1093/nar/gkv007 · ExternalCitation · doi-reference
The GTEx consortium atlas of genetic regulatory effects across human tissues
10.1126/science.aaz1776 · ExternalCitation · doi-reference
Pituitary expression of CTLA-4 mediates hypophysitis secondary to administration of CTLA-4 blocking antibody
10.1126/scitranslmed.3008002 · ExternalCitation · doi-reference
Targeting the neuro-immune crosstalk in breast cancer brain metastases
10.1136/jitc-2025-014134 · ExternalCitation · doi-reference
Biochemistry and physiology of mammalian secreted phospholipases A2
10.1146/annurev.biochem.76.062405.154007 · ExternalCitation · doi-reference
The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data
10.1158/2159-8290.cd-12-0095 · ExternalCitation · doi-reference
Prolactin: a stimulator of disease activity in systemic lupus erythematosus
10.1177/096120339500400102 · ExternalCitation · doi-reference
Clinical value of RNA sequencing-based classifiers for prediction of the five conventional breast cancer biomarkers: a report from the population-based multicenter Sweden cancerome analysis network – breast initiative
10.1200/po.17.00135 · ExternalCitation · doi-reference
Autoimmune hypophysitis
10.1210/er.2004-0011 · ExternalCitation · doi-reference
New concepts in prolactin biology
10.1677/joe-10-0069 · ExternalCitation · doi-reference
Neuroendocrine regulation of autoimmune/inflammatory disease
10.1677/joe.0.1690429 · ExternalCitation · doi-reference
lifelines: survival analysis in Python
10.21105/joss.01317 · ExternalCitation · doi-reference
Neuro-immune crosstalk in breast cancer: molecular mechanisms from stress signals to immune escape
10.3389/fimmu.2026.1790195 · ExternalCitation · doi-reference
Expanding roles of secreted phospholipase A2 in biological systems
10.3390/biom10101457 · ExternalCitation · doi-reference
CXCL17 is a mucosal chemokine elevated in idiopathic pulmonary fibrosis that exhibits broad antimicrobial and immunomodulatory activity
10.4049/jimmunol.1102903 · ExternalCitation · doi-reference
