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References from Current trends in the clinical application of tissue-engineered scaffolds for cutaneous wound healing: A narrative review. Local targets link to admitted publications; unresolved targets remain external evidence.
An economic evaluation of the impact, cost, and medicare policy implications of chronic nonhealing wounds
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Incidence, prevalence, and medical costs of pressure injuries in Taiwan from 2001 to 2015: results of a retrospective cohort study
2024 · External reference
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10.1126/science.8493529 · 1993 · External reference
Advancement of wound care from grafts to bioengineered smart skin substitutes
10.1007/s40204-014-0030-y · 2014 · External reference
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10.1038/nature05664 · 2007 · External reference
Biomaterials for skin substitutes
10.1002/adhm.201700897 · 2018 · External reference
Tissue-engineered skin substitutes: an overview
10.1007/s10047-013-0734-0 · 2013 · External reference
Skin substitutes for acute and chronic wound healing: an updated review
10.1080/09546634.2018.1530443 · 2020 · External reference
Biologic and synthetic skin substitutes: an overview
10.4103/0970-0358.70712 · 2010 · External reference
Air-jet spun tissue engineering scaffolds incorporated with diamond nanosheets with improved mechanical strength and biocompatibility
2022 · External reference
Nitric oxide-releasing biomaterials for promoting wound healing in impaired diabetic wounds: state of the art and recent trends
10.1016/j.biopha.2022.112707 · 2022 · External reference
The principles of wound healing
2010 · External reference
Novel poly(ester urethane urea)/polydioxanone blends: electrospun fibrous meshes and films
10.3390/molecules26133847 · 2021 · External reference
Signalling pathways triggering therapeutic marine algae-derived natural polysaccharides for effective wound healing: a recent review
10.1016/j.carbpol.2025.124253 · 2025 · External reference
Skin wound healing assisted by angiogenic targeted tissue engineering: a comprehensive review of bioengineered approaches
10.1002/jbm.a.37105 · 2020 · External reference
Nanomaterials for the delivery of bioactive factors to enhance angiogenesis of dermal substitutes during wound healing
10.1093/burnst/tkab049 · 2022 · External reference
Titanium nanorods loaded PCL meshes with enhanced blood vessel formation and cell migration for wound dressing applications
10.1002/mabi.201900058 · 2019 · External reference
Cerium oxide nanoparticle incorporated electrospun poly(3-hydroxybutyrate-co-3-hydroxyvalerate) membranes for diabetic wound healing applications
10.1021/acsbiomaterials.8b01352 · 2019 · External reference
Regulatory processes of the canonical Wnt/β-catenin pathway and photobiomodulation in diabetic wound repair
10.3390/ijms23084210 · 2022 · External reference
Preliminary study on human adipose stem cells promoting skin wound healing through notch signaling pathway
10.2174/1574888x18666221216123259 · 2023 · External reference
Jagged-1+ skin Tregs modulate cutaneous wound healing
10.1038/s41598-024-71512-1 · 2024 · External reference
Hedgehog signaling in papillary fibroblasts is essential for hair follicle regeneration during wound healing
10.1016/j.jid.2021.11.026 · 2022 · External reference
Programmed BRD9 degradation and hedgehog signaling activation via silk-based core-shell microneedles promote diabetic wound healing
2024 · External reference
Preventing engrailed-1 activation in fibroblasts yields wound regeneration without scarring
10.1126/science.aba2374 · 2021 · External reference
Implant fibrosis and the underappreciated role of myofibroblasts in the foreign body reaction
10.3390/cells10071794 · 2021 · External reference
Mechanical forces in skin disorders
10.1016/j.jdermsci.2018.03.004 · 2018 · External reference
A bioengineered living cell construct activates an acute wound healing response in venous leg ulcers
10.1126/scitranslmed.aaf8611 · 2017 · External reference
Covering skin defects with a xenogeneic collagen matrix in comparison with a skin graft – a multicenter randomized controlled trial
10.1016/j.jcms.2023.10.009 · 2024 · External reference
Extracellular matrix-based biomaterials in burn wound repair: a promising therapeutic strategy
10.1016/j.ijbiomac.2024.137633 · 2024 · External reference
Emerging and innovative approaches for wound healing and skin regeneration: current status and advances
10.1016/j.biomaterials.2019.119267 · 2019 · External reference
A universal classification system of skin substitutes inspired by factorial design
10.1089/ten.teb.2017.0477 · 2018 · External reference
Fish collagen/alginate/chitooligosaccharides integrated scaffold for skin tissue regeneration application
10.1016/j.ijbiomac.2015.08.038 · 2015 · External reference
Comprehensive review of hybrid collagen and silk fibroin for cutaneous wound healing
10.3390/ma13143097 · 2020 · External reference
Evaluation of a cross-linked versus non-cross-linked collagen matrix in full-thickness skin defects
10.1016/j.burns.2020.03.018 · 2020 · External reference
Silk biomaterials in wound healing and skin regeneration therapeutics: from bench to bedside
10.1016/j.actbio.2019.11.050 · 2019 · External reference
Allantoin-functionalized silk fibroin/sodium alginate transparent scaffold for cutaneous wound healing
10.1016/j.ijbiomac.2022.03.147 · 2022 · External reference
Wound healing properties of a fibrin-based dermal replacement scaffold
2021 · External reference
Tropoelastin incorporation into a dermal regeneration template promotes wound angiogenesis
10.1002/adhm.201400571 · 2014 · External reference
Electrospun chitosan membranes containing bioactive and therapeutic agents for enhanced wound healing
10.1016/j.ijbiomac.2020.03.207 · 2020 · External reference
Chitosan/glycosaminoglycan scaffolds for skin reparation
10.1016/j.carbpol.2019.05.069 · 2019 · External reference
Cationic, anionic and neutral polysaccharides for skin tissue engineering and wound healing applications
10.1016/j.ijbiomac.2021.10.013 · 2021 · External reference
The latest achievements in plant cellulose-based biomaterials for tissue engineering focusing on skin repair
2021 · External reference
Dextran, as a biological macromolecule for the development of bioactive wound dressing materials: a review of recent progress and future perspectives
10.1016/j.ijbiomac.2022.02.114 · 2022 · External reference
Structural and surface compatibility study of modified electrospun poly(ε-caprolactone) (pcl) composites for skin tissue engineering
10.1208/s12249-016-0500-8 · 2016 · External reference
Antibacterial electrospun polycaprolactone nanofibers reinforced by halloysite nanotubes for tissue engineering
10.3390/polym14040746 · 2022 · External reference
Skin wound repair: results of a pre-clinical study to evaluate electropsun collagen-elastin-PCL scaffolds as dermal substitutes
10.1016/j.burns.2019.04.014 · 2019 · External reference
Hybrid PCL/chitosan-PEO nanofibrous scaffolds incorporated with a euchroma extract for skin tissue engineering application
2021 · External reference
Bioactive inorganic particles-based biomaterials for skin tissue engineering
10.1002/exp.20210083 · 2022 · External reference
Advanced multifunctional wound dressing hydrogels as drug carriers
10.1002/mabi.202200111 · 2022 · External reference
Electrospun scaffold-based antibiotic therapeutics for chronic wound recovery
10.2174/1389557523666230221155544 · 2023 · External reference
Collagen-based nanofibers for skin regeneration and wound dressing applications
10.3390/polym13244368 · 2021 · External reference
Photosensitive and biomimetic core-shell nanofibrous scaffolds as wound dressing
10.1111/php.12238 · 2014 · External reference
Electrospun PLGA/SF/artemisinin composite nanofibrous membranes for wound dressing
10.1016/j.ijbiomac.2021.04.021 · 2021 · External reference
Low-temperature plasma techniques in biomedical applications and therapeutics: an overview
10.3390/ijms25010524 · 2023 · External reference
Skin tissue engineering using 3D bioprinting: an evolving research field
10.1016/j.bjps.2017.12.006 · 2017 · External reference
The applications of 3D printing in wound healing: the external delivery of stem cells and antibiosis
10.1016/j.addr.2023.114823 · 2023 · External reference
Three-dimensionally printed skin substitute using human dermal fibroblasts and human epidermal keratinocytes
10.1097/sap.0000000000002886 · 2021 · External reference
3D bioprinted biomask for facial skin reconstruction
10.1016/j.bprint.2018.e00028 · 2018 · External reference
3D-printing of solvent exchange deposition modeling (SEDM) for a bilayered flexible skin substitute of poly (lactide-co-glycolide) with bioorthogonally engineered EGF
10.1016/j.msec.2020.110942 · 2020 · External reference
3D bioprinted alginate/chitosan-based sandwich-structured wound dressing with dual-drug release for enhanced skin regeneration
10.1016/j.ijbiomac.2025.148428 · 2025 · External reference
Nanomaterials and nanotechnology for skin tissue engineering
2012 · External reference
Functional hydrogels as wound dressing to enhance wound healing
10.1021/acsnano.1c04206 · 2021 · External reference
Biomimetic gradient hydrogel with fibroblast spheroids for full-thickness skin regeneration
2024 · External reference
Pioneering 3D and 4D bioprinting strategies for advanced wound management: from design to healing
10.1002/smll.202506259 · 2025 · External reference
3D and 4D bioprinting technologies: a game changer for the biomedical sector?
10.1007/s10439-023-03243-9 · 2023 · External reference
4D printing of biological macromolecules employing handheld bioprinters for in situ wound healing applications
10.1016/j.ijbiomac.2024.135999 · 2024 · External reference
Wearable technology for chronic wound monitoring: current dressings, advancements, and future prospects
10.3389/fbioe.2018.00047 · 2018 · External reference
Next-generation smart wound dressings: AI integration, biosensors, and electrospun nanofibers for chronic wound therapy
10.1080/09205063.2025.2540362 · 2025 · External reference
Biosensor technologies and smart dressings for chronic wound monitoring: a systematic review
10.1111/wrr.70175 · 2026 · External reference
Predicting inflammatory response of biomimetic nanofibre scaffolds for tissue regeneration using machine learning and graph theory
10.1039/d4tb02494j · 2025 · External reference
The use of dermal substitute in the treatment of burns as a complication of type 2 diabetes mellitus and diabetic foot syndrome
10.1177/15347346241262061 · 2026 · External reference
Human amniotic membrane vs collagen in the treatment of superficial second-degree burns in children
10.25270/wnds/2022.135140 · 2022 · External reference
Clinical efficacy of rhGM-CSF gel and medical collagen sponge on deep second-degree burns of infants: a randomized clinical trial
2024 · External reference
A clinical trial with a novel collagen dermal substitute for wound healing in burn patients
10.1039/c9bm01209e · 2020 · External reference
Glyaderm(®) dermal substitute: clinical application and long-term results in 55 patients
10.1016/j.burns.2014.05.013 · 2014 · External reference
A histological and clinical study of MatriDerm® use in burn reconstruction
10.1093/jbcr/irad024 · 2023 · External reference
Randomized, paired-site comparison of autologous engineered skin substitutes and split-thickness skin graft for closure of extensive, full-thickness burns
10.1097/bcr.0000000000000401 · 2017 · External reference
Wound healing and dermal regeneration in severe burn patients treated with Novosorb® biodegradable temporising matrix: a prospective clinical study
10.1016/j.burns.2021.07.014 · 2021 · External reference
Clinical effectiveness of an acellular dermal regenerative tissue matrix compared to standard wound management in healing diabetic foot ulcers: a prospective, randomised, multicentre study
10.1111/j.1742-481x.2009.00585.x · 2009 · External reference
Clinical efficacy of acellular dermal matrix paste in treating diabetic foot ulcers
2020 · External reference
Wound conforming matrix containing purified homogenate of dermal collagen promotes healing of diabetic neuropathic foot ulcers: comparative analysis versus standard of care
10.1089/wound.2019.1024 · 2020 · External reference
The incidence of lower-extremity amputation and bone resection in diabetic foot ulcer patients treated with a human fibroblast-derived dermal substitute
10.1097/01.asw.0000456630.12766.e9 · 2015 · External reference
A clinical trial of integra template for diabetic foot ulcer treatment
10.1111/wrr.12357 · 2015 · External reference
Hyaluronic acid dressing (Healoderm) in the treatment of diabetic foot ulcer: a prospective, randomized, placebo-controlled, single-center study
10.1111/wrr.12428 · 2016 · External reference
Use of biodegradable temporising matrix (BTM) in the reconstruction of diabetic foot wounds: a pilot study
2022 · External reference
Improved wound healing of diabetic foot ulcers using human placenta-derived mesenchymal stem cells in gelatin electrospun nanofibrous scaffolds plus a platelet-rich plasma gel: a randomized clinical trial
10.1016/j.intimp.2021.108282 · 2021 · External reference
Evaluation of tissue engineering products for the management of neuropathic diabetic foot ulcers: an interim analysis
10.12968/jowc.2016.25.sup7.s18 · 2016 · External reference
Wound closure in patients with DFU: a cost-effectiveness analysis of two cellular/tissue-derived products
10.12968/jowc.2015.24.3.149 · 2015 · External reference
Human acellular dermal wound matrix for complex diabetic wounds
10.12968/jowc.2016.25.sup4.s17 · 2016 · External reference
Prevalence and incidence of venous leg ulcers—a systematic review and meta-analysis
10.1111/iwj.14272 · 2023 · External reference
Venous ulcers treated with a hyaluronic acid extracellular matrix and compression therapy: interim analysis of a randomized controlled trial, wounds compend
2017 · External reference
Hyaluronic acid-based dermal substitute with stromal vascular fraction vs. partial thickness skin grafts for the treatment of intermediate-deep burns of the hand: a retrospective case-control study
2024 · External reference
The vegetal biomembrane in the healing of chronic venous ulcers
10.1590/s0365-05962012000100005 · 2012 · External reference
Randomized, prospective, blinded-enrollment, head-to-head venous leg ulcer healing trial comparing living, bioengineered skin graft substitute (Apligraf) with living, cryopreserved, human skin allograft (TheraSkin)
10.1016/j.cpm.2018.02.006 · 2018 · External reference
Effectiveness of an acellular synthetic matrix in the treatment of hard-to-heal leg ulcers
10.1111/iwj.12115 · 2013 · External reference
Purified type I collagen wound matrix improves chronic wound healing in patients with recessive dystrophic epidermolysis bullosa
10.1111/pde.12492 · 2015 · External reference
Safety and wound outcomes following genetically corrected autologous epidermal grafts in patients with recessive dystrophic epidermolysis bullosa
10.1001/jama.2016.15588 · 2016 · External reference
Combining acellular dermal grafts with negative-pressure wound therapy in a postsurgical wound: a case report
10.1097/asw.0000000000000435 · 2026 · External reference
Novel use of a combination of extracellular matrices for wound healing following resection of a large inferior eyelid mass in a miniature hereford
10.2460/javma.257.8.833 · 2020 · External reference
Scarring at donor sites after split-thickness skin graft: a prospective, longitudinal, randomized trial
10.1097/01.asw.0000720256.45983.28 · 2020 · External reference
Bioengineering skin substitutes for wound management: perspectives and challenges
10.3390/ijms25073702 · 2024 · External reference
Navigating the regulatory pathways and requirements for tissue-engineered products in the treatment of burns in the United States
10.1093/jbcr/iraa210 · 2021 · External reference
Advances in spray products for skin regeneration
2022 · External reference
Commercialization of skin substitutes for third-degree burn wounds
10.1016/j.tibtech.2023.10.005 · 2023 · External reference
Advances in skin substitutes-potential of tissue engineered skin for facilitating anti-fibrotic healing
10.3390/jfb6030547 · 2015 · External reference
Design and evaluation of microemulsion-based drug delivery systems for biofilm-based infection in burns
10.1208/s12249-024-02909-4 · 2024 · External reference
Membranes for periodontal regeneration—a materials perspective
10.1159/000381699 · 2015 · External reference
Nanofiber scaffold gradients for interfacial tissue engineering
10.1177/0885328211423783 · 2012 · External reference
Using stem cells in skin regeneration: possibilities and reality
10.1089/scd.2011.0539 · 2012 · External reference
Use of mesenchymal stem cells for cutaneous repair and skin substitute elaboration
10.1016/j.patbio.2014.01.002 · 2014 · External reference
Acceleration of diabetic wound regeneration using an in situ-formed stem-cell-based skin substitute
10.1002/adhm.201800432 · 2018 · External reference
Tissue-engineered dermo-epidermal skin grafts prevascularized with adipose-derived cells
10.1016/j.biomaterials.2014.02.049 · 2014 · External reference
In vitro engineering of a skin substitute based on adipose-derived stem cells
10.1159/000501071 · 2019 · External reference
Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing
10.1186/s13287-023-03345-0 · 2023 · External reference
Recent progress in mesenchymal stem cell-derived exosomes for skin wound repair
10.1007/s12013-024-01328-3 · 2024 · External reference
Extracellular vesicles derived from mesenchymal stem cells (MSC) in regenerative medicine: applications in skin wound healing
10.3389/fbioe.2020.00146 · 2020 · External reference
VH298-loaded extracellular vesicles released from gelatin methacryloyl hydrogel facilitate diabetic wound healing by HIF-1α-mediated enhancement of angiogenesis
10.1016/j.actbio.2022.05.018 · 2022 · External reference
Exosome laden oxygen releasing antioxidant and antibacterial cryogel wound dressing OxOBand alleviate diabetic and infectious wound healing
10.1016/j.biomaterials.2020.120020 · 2020 · External reference
Composition and performance of autologous engineered skin substitutes for repair or regeneration of excised, full-thickness burns
10.1093/jbcr/irac107 · 2023 · External reference
A randomized clinical trial of a human acellular dermal matrix demonstrated superior healing rates for chronic diabetic foot ulcers over conventional care and an active acellular dermal matrix comparator
10.1111/wrr.12551 · 2017 · External reference
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10.1111/iwj.12395 · 2015 · External reference
A prospective, randomized, multicenter, controlled evaluation of the use of dehydrated amniotic membrane allograft compared to standard of care for the closure of chronic diabetic foot ulcer, wounds compend
2016 · External reference
Outcomes of dermal substitutes in burns and burn scar reconstruction: a systematic review and meta-analysis
10.1111/wrr.13226 · 2024 · External reference
Histopathological assessment of OASIS Ultra on critical-sized wound healing: a pilot study
10.1111/cup.12925 · 2017 · External reference
Burn-wound healing effect of gelatin/polyurethane nanofiber scaffold containing silver-sulfadiazine
10.1166/jbn.2013.1509 · 2013 · External reference
Construction of tissue-engineered skin with rete ridges using co-network hydrogels of gelatin methacrylated and poly(ethylene glycol) diacrylate
10.1016/j.msec.2021.112360 · 2021 · External reference
Cell-loaded genipin cross-linked collagen/gelatin skin substitute adorned with zinc-doped bioactive glass-ceramic for cutaneous wound regeneration
10.1016/j.ijbiomac.2023.125898 · 2023 · External reference
Streamlining skin regeneration: a ready-to-use silk bilayer wound dressing
10.3390/gels10070439 · 2024 · External reference
Fibrin gel as a scaffold for skin substitute – production and clinical experience
2016 · External reference
Engineered skin graft with stromal vascular fraction cells encapsulated in fibrin–collagen hydrogel: a clinical study for diabetic wound healing
10.1002/term.3003 · 2020 · External reference
Solution blow spinning of highly deacetylated chitosan nanofiber scaffolds for dermal wound healing
10.1016/j.bioadv.2022.212871 · 2022 · External reference
Chitosan-poly(caprolactone) nanofibers for skin repair
10.1039/c6tb03223k · 2017 · External reference
A biomimetic composite bilayer dressing composed of alginate and fibroin for enhancing full-thickness wound healing
10.1002/mabi.202100352 · 2022 · External reference
Prospective and randomised evaluation of the protease-modulating effect of oxidised regenerated cellulose/collagen matrix treatment in pressure sore ulcers
10.1111/iwj.12449 · 2016 · External reference
Enhanced wound-healing capability with inherent antimicrobial activities of usnic acid incorporated poly(ε-caprolactone)/decellularized extracellular matrix nanofibrous scaffold
10.1016/j.bioadv.2022.213046 · 2022 · External reference
Polydopamine biomaterials for skin regeneration
10.1021/acsbiomaterials.1c01436 · 2022 · External reference
Amniotic membrane and its epithelial and mesenchymal stem cells as an appropriate source for skin tissue engineering and regenerative medicine
10.1080/21691401.2018.1458730 · 2018 · External reference
Engineering vascularizing electrospun dermal grafts by integrating fish collagen and ion-doped bioactive glass
10.1021/acsbiomaterials.1c01098 · 2022 · External reference
Development of chitosan-based cerium and titanium oxide loaded polycaprolactone for cutaneous wound healing and antibacterial applications
2023 · External reference
Recent prospective of nanofiber scaffolds fabrication approaches for skin regeneration
10.3109/21691401.2015.1111232 · 2015 · External reference
Fibroblast-loaded cholecyst-derived scaffold induces faster healing of full thickness burn wound in rabbit
10.1177/0885328215615759 · 2015 · External reference
3D printable, injectable amyloid-based composite hydrogel of bovine serum albumin and aloe vera for rapid diabetic wound healing
10.1039/d3tb01151h · 2023 · External reference
Properties of dehydrated human amnion/chorion composite grafts: implications for wound repair and soft tissue regeneration
10.1002/jbm.b.33141 · 2014 · External reference
Human acellular dermal matrix allograft: a randomized, controlled human trial for the long-term evaluation of patients with extensive burns
10.1016/j.burns.2014.12.007 · 2015 · External reference
The use of acellular porcine dermis, hyaluronic acid and polynucleotides in the treatment of cutaneous ulcers: single blind randomised clinical trial
10.1111/iwj.13454 · 2020 · External reference
Revisiting the role of amniotic membrane dressing in acute large traumatic wounds: a randomized feasibility study at a level 1 trauma centre
2023 · External reference