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References from Beyond HPV positivity: Sex, host biology and contextual heterogeneity in oropharyngeal cancer. Local targets link to admitted publications; unresolved targets remain external evidence.
Human papillomavirus and survival of patients with oropharyngeal cancer
10.1056/nejmoa0912217 · 2010 · External reference
Oropharyngeal cancer risk groups in the United States: a meta-analysis and SEER analysis
10.1186/s12885-025-14904-4 · 2025 · External reference
Pan-cancer integrative histology-genomic analysis via multimodal deep learning
10.1016/j.ccell.2022.07.004 · 2022 · External reference
Oral HPV incidence and risk factors for acquisition
10.1016/j.oraloncology.2025.107249 · 2025 · External reference
Persistence and clearance of oral human papillomavirus among multi-national cohort of men
10.1038/s41467-025-62963-9 · 2025 · External reference
The biology and life-cycle of human papillomaviruses
10.1016/j.vaccine.2012.06.083 · 2012 · External reference
Papillomaviruses and cancer: commonalities and differences in HPV carcinogenesis at different sites of the body
10.1007/s10147-023-02340-y · 2023 · External reference
Current challenges and potential opportunities for interception and prevention of head and neck cancer
10.1093/carcin/bgaf025 · 2025 · External reference
An integrated approach for preventing Oral Cavity and oropharyngeal cancers: two etiologies with distinct and shared mechanisms of carcinogenesis
10.1158/1940-6207.capr-20-0096 · 2020 · External reference
The influence of smoking and co-morbidity on dose achievement in primary or adjuvant radio(chemo)therapy in head and neck squamous cell carcinoma (HNSCC)
10.3389/fonc.2020.00398 · 2020 · External reference
Oropharyngeal carcinoma with special focus on HPV-related squamous cell carcinoma
10.1146/annurev-pathmechdis-031521-041424 · 2023 · External reference
Accuracy of p16 IHC in classifying HPV-driven OPSCC in different populations
10.3390/cancers15030656 · 2023 · External reference
Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal (NRG Oncology RTOG 1016): a randomized, multicenter, non-inferiority trial
10.1016/s0140-6736(18)32779-x · 2019 · External reference
Spatiotemporally deciphering the mysterious mechanism of persistent HPV-induced malignant transition and immune remodeling from HPV-infected normal cervix, precancer to cervical cancer: integrating single-cell RNA-sequencing and spatial transcriptome
10.1002/ctm2.1219 · 2023 · External reference
Tumor-infiltrating B cells affect the progression of oropharyngeal squamous cell carcinoma via cell-to-cell interactions with CD8+ T cells
10.1186/s40425-019-0726-6 · 2019 · External reference
Mechanistic insights into HPV-positivity in non-smokers and HPV-negativity in smokers with head and neck cancer
10.3389/fonc.2024.1484319 · 2025 · External reference
The interaction of smoking habit, SLPI and AnxA2 in HPV associated head and neck and other cancers
2021 · External reference
Influence of HPV status on survival of patients with tonsillar carcinomas (TSCC) treated by CO2-laser plus risk adapted therapy – A 10 year retrospective single centre study
10.1016/j.canlet.2017.10.045 · 2018 · External reference
HPV DNA, E6*I-mRNA expression and p16INK4A immunohistochemistry in head and neck cancer – How valid is p16INK4A as surrogate marker?
10.1016/j.canlet.2012.03.033 · 2012 · External reference
Decoding pan-cancer treatment outcomes using multimodal real-world data and explainable artificial intelligence
10.1038/s43018-024-00891-1 · 2025 · External reference
Sex-specific aspects in patients with oropharyngeal squamous cell carcinoma: a bicentric cohort study
10.1186/s12885-023-11526-6 · 2023 · External reference
Sex differences in immune response
10.1038/nri.2016.90 · 2016 · External reference
Human papillomavirus testing in head and neck carcinomas
10.5858/arpa.2024-0388-cp · 2025 · External reference
Clinical, morphologic and molecular heterogeneity of HPV-associated oropharyngeal cancer
10.1038/s41388-023-02819-y · 2023 · External reference
Gender and race interact to influence survival disparities in head and neck cancer
10.1016/j.oraloncology.2020.105093 · 2021 · External reference
Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled phase 3 trial
10.1016/s0140-6736(18)32752-1 · 2019 · External reference
Prognostic implications of p16 and HPV discordance in oropharyngeal cancer (HNCIG-EPIC-OPC): a multicenter, multinational, individual patient data analysis
10.1016/s1470-2045(23)00013-x · 2023 · External reference
Spatial evidence for carcinoma in situ (CIS) as an entity in human papillomavirus (HPV)-associated tonsillar squamous cell carcinoma (TSCC)
10.1002/ijc.70207 · 2026 · External reference
No association between HPV-status in tonsillar tissue and sexual behavior of the patients in a northern German population – Critical view of the link between HPV natural history and HPV-driven carcinogenesis
10.1016/j.pvr.2020.100207 · 2020 · External reference
Geographical and anatomical influences on human papillomavirus prevalence diversity in head and neck squamous cell carcinoma in Germany
10.3892/ijo.2014.2697 · 2015 · External reference
HPV DNA/RNA detection in various oral and oropharyngeal biomaterials identifies active HPV infections also in non-neoplastic tonsils
10.1016/j.tranon.2020.101002 · 2021 · External reference
Low human papillomavirus prevalence in head and neck cancer: results from two large case-control studies in high-incidence regions
10.1093/ije/dyq249 · 2011 · External reference
IPVS consensus statement on the natural history of cervical human papillomavirus infection
10.1093/infdis/jiaf574 · 2026 · External reference
Genome-wide host methylation profiling of anal and cervical carcinoma
10.1371/journal.pone.0260857 · 2021 · External reference
Oral manifestation of human papillomavirus infections
10.1111/eos.12538 · 2018 · External reference
Lack of de-intensification models for female head and neck cancer patients with favorable prognosis
10.1002/cam4.71734 · 2026 · External reference
Trends in human papillomavirus-associated cancers – United States, 1999-2015
10.15585/mmwr.mm6733a2 · 2018 · External reference
TNM8 staging system beyond p16: double HPV/p16 status is superior to p16 alone in predicting outcome in oropharyngeal squamous cell carcinoma
10.1016/j.ejca.2024.114329 · 2024 · External reference
Oropharyngeal cancer outcomes correlate with p16 status, multinucleation and immune infiltration
10.1038/s41379-022-01024-8 · 2022 · External reference
Persistence and clearance of oral human papillomavirus infections: a prospective population-based cohort study
10.1002/jmv.26130 · 2020 · External reference
The S100A10 subunit of the annexin A2 heterotetramer facilitates L2-mediated human papillomavirus infection
10.1371/journal.pone.0043519 · 2012 · External reference
Lack of de-intensification models for female head and neck cancer patients with favorable prognosis
10.1002/cam4.71734 · ExternalCitation · doi-reference
Spatiotemporally deciphering the mysterious mechanism of persistent HPV-induced malignant transition and immune remodeling from HPV-infected normal cervix, precancer to cervical cancer: integrating single-cell RNA-sequencing and spatial transcriptome
10.1002/ctm2.1219 · ExternalCitation · doi-reference
Spatial evidence for carcinoma in situ (CIS) as an entity in human papillomavirus (HPV)-associated tonsillar squamous cell carcinoma (TSCC)
10.1002/ijc.70207 · ExternalCitation · doi-reference
Persistence and clearance of oral human papillomavirus infections: a prospective population-based cohort study
10.1002/jmv.26130 · ExternalCitation · doi-reference
Papillomaviruses and cancer: commonalities and differences in HPV carcinogenesis at different sites of the body
10.1007/s10147-023-02340-y · ExternalCitation · doi-reference
HPV DNA, E6*I-mRNA expression and p16INK4A immunohistochemistry in head and neck cancer – How valid is p16INK4A as surrogate marker?
10.1016/j.canlet.2012.03.033 · ExternalCitation · doi-reference
Influence of HPV status on survival of patients with tonsillar carcinomas (TSCC) treated by CO2-laser plus risk adapted therapy – A 10 year retrospective single centre study
10.1016/j.canlet.2017.10.045 · ExternalCitation · doi-reference
Pan-cancer integrative histology-genomic analysis via multimodal deep learning
10.1016/j.ccell.2022.07.004 · ExternalCitation · doi-reference
TNM8 staging system beyond p16: double HPV/p16 status is superior to p16 alone in predicting outcome in oropharyngeal squamous cell carcinoma
10.1016/j.ejca.2024.114329 · ExternalCitation · doi-reference
Gender and race interact to influence survival disparities in head and neck cancer
10.1016/j.oraloncology.2020.105093 · ExternalCitation · doi-reference
Oral HPV incidence and risk factors for acquisition
10.1016/j.oraloncology.2025.107249 · ExternalCitation · doi-reference
No association between HPV-status in tonsillar tissue and sexual behavior of the patients in a northern German population – Critical view of the link between HPV natural history and HPV-driven carcinogenesis
10.1016/j.pvr.2020.100207 · ExternalCitation · doi-reference
HPV DNA/RNA detection in various oral and oropharyngeal biomaterials identifies active HPV infections also in non-neoplastic tonsils
10.1016/j.tranon.2020.101002 · ExternalCitation · doi-reference
The biology and life-cycle of human papillomaviruses
10.1016/j.vaccine.2012.06.083 · ExternalCitation · doi-reference
Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled phase 3 trial
10.1016/s0140-6736(18)32752-1 · ExternalCitation · doi-reference
Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal (NRG Oncology RTOG 1016): a randomized, multicenter, non-inferiority trial
10.1016/s0140-6736(18)32779-x · ExternalCitation · doi-reference
Prognostic implications of p16 and HPV discordance in oropharyngeal cancer (HNCIG-EPIC-OPC): a multicenter, multinational, individual patient data analysis
10.1016/s1470-2045(23)00013-x · ExternalCitation · doi-reference
Sex differences in immune response
10.1038/nri.2016.90 · ExternalCitation · doi-reference
Oropharyngeal cancer outcomes correlate with p16 status, multinucleation and immune infiltration
10.1038/s41379-022-01024-8 · ExternalCitation · doi-reference
Clinical, morphologic and molecular heterogeneity of HPV-associated oropharyngeal cancer
10.1038/s41388-023-02819-y · ExternalCitation · doi-reference
Persistence and clearance of oral human papillomavirus among multi-national cohort of men
10.1038/s41467-025-62963-9 · ExternalCitation · doi-reference
Decoding pan-cancer treatment outcomes using multimodal real-world data and explainable artificial intelligence
10.1038/s43018-024-00891-1 · ExternalCitation · doi-reference
Human papillomavirus and survival of patients with oropharyngeal cancer
10.1056/nejmoa0912217 · ExternalCitation · doi-reference
Current challenges and potential opportunities for interception and prevention of head and neck cancer
10.1093/carcin/bgaf025 · ExternalCitation · doi-reference
Low human papillomavirus prevalence in head and neck cancer: results from two large case-control studies in high-incidence regions
10.1093/ije/dyq249 · ExternalCitation · doi-reference
IPVS consensus statement on the natural history of cervical human papillomavirus infection
10.1093/infdis/jiaf574 · ExternalCitation · doi-reference
Oral manifestation of human papillomavirus infections
10.1111/eos.12538 · ExternalCitation · doi-reference
Oropharyngeal carcinoma with special focus on HPV-related squamous cell carcinoma
10.1146/annurev-pathmechdis-031521-041424 · ExternalCitation · doi-reference
An integrated approach for preventing Oral Cavity and oropharyngeal cancers: two etiologies with distinct and shared mechanisms of carcinogenesis
10.1158/1940-6207.capr-20-0096 · ExternalCitation · doi-reference
Sex-specific aspects in patients with oropharyngeal squamous cell carcinoma: a bicentric cohort study
10.1186/s12885-023-11526-6 · ExternalCitation · doi-reference
Oropharyngeal cancer risk groups in the United States: a meta-analysis and SEER analysis
10.1186/s12885-025-14904-4 · ExternalCitation · doi-reference
Tumor-infiltrating B cells affect the progression of oropharyngeal squamous cell carcinoma via cell-to-cell interactions with CD8+ T cells
10.1186/s40425-019-0726-6 · ExternalCitation · doi-reference
The S100A10 subunit of the annexin A2 heterotetramer facilitates L2-mediated human papillomavirus infection
10.1371/journal.pone.0043519 · ExternalCitation · doi-reference
Genome-wide host methylation profiling of anal and cervical carcinoma
10.1371/journal.pone.0260857 · ExternalCitation · doi-reference
Trends in human papillomavirus-associated cancers – United States, 1999-2015
10.15585/mmwr.mm6733a2 · ExternalCitation · doi-reference
The influence of smoking and co-morbidity on dose achievement in primary or adjuvant radio(chemo)therapy in head and neck squamous cell carcinoma (HNSCC)
10.3389/fonc.2020.00398 · ExternalCitation · doi-reference
Mechanistic insights into HPV-positivity in non-smokers and HPV-negativity in smokers with head and neck cancer
10.3389/fonc.2024.1484319 · ExternalCitation · doi-reference
Accuracy of p16 IHC in classifying HPV-driven OPSCC in different populations
10.3390/cancers15030656 · ExternalCitation · doi-reference
Geographical and anatomical influences on human papillomavirus prevalence diversity in head and neck squamous cell carcinoma in Germany
10.3892/ijo.2014.2697 · ExternalCitation · doi-reference
Human papillomavirus testing in head and neck carcinomas
10.5858/arpa.2024-0388-cp · ExternalCitation · doi-reference