Research graph
References from Purinergic control of inflammation and thrombosis: Role of P2X1 receptors. Local targets link to admitted publications; unresolved targets remain external evidence.
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Inter- and intrasubunit interactions between transmembrane helices in the open state of P2X receptor channels
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Overexpression of the platelet P2X1 ion channel in transgenic mice generates a novel prothrombotic phenotype
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ERK2 activation in arteriolar and venular murine thrombosis: platelet receptor GPIb vs. P2X(1)
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Activation of receptor-operated cation channels via P2X1 not P2T purinoceptors in human platelets
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P2X(1)-mediated activation of extracellular signal-regulated kinase 2 contributes to platelet secretion and aggregation induced by collagen
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The ATP-gated P2X1 receptor plays a pivotal role in activation of aspirin-treated platelets by thrombin and epinephrine
10.1074/jbc.m800358200 · 2008 · External reference
Toll-like receptor 2 stimulation of platelets is mediated by purinergic P2X1-dependent Ca2+ mobilisation, cyclooxygenase and purinergic P2Y1 and P2Y12 receptor activation
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Platelet Ca(2+) responses coupled to glycoprotein vi and toll-like receptors persist in the presence of endothelial-derived inhibitors: roles for secondary activation of P2X1 receptors and release from intracellular Ca(2+) stores
10.1182/blood-2011-10-386052 · 2012 · External reference
P2X1 ion channels promote neutrophil chemotaxis through rho kinase activation
10.4049/jimmunol.0804007 · 2009 · External reference
ATP-gated P2X1 ion channels protect against endotoxemia by dampening neutrophil activation
10.1111/j.1538-7836.2011.04606.x · 2012 · External reference
10.1038/nm.2184
10.1038/nm.2184 · External reference
P2X1 expressed on polymorphonuclear neutrophils and platelets is required for thrombosis in mice
10.1182/blood-2014-04-571679 · 2014 · External reference
10.1523/jneurosci.1149-08.2008
10.1523/jneurosci.1149-08.2008 · External reference
P2X1 purinoceptor in human platelets. Molecular cloning and functional characterization after heterologous expression
1998 · External reference
Quantification of ADP and ATP receptor expression in human platelets
10.1046/j.1538-7836.2003.00070.x · 2003 · External reference
A study of P2X1 receptor function in murine megakaryocytes and human platelets reveals synergy with P2Y receptors
10.1038/sj.bjp.0704486 · 2002 · External reference
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10.1126/science.1132559 · External reference
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10.1152/ajpcell.2000.279.4.c1189 · External reference
Effects of purine and pyrimidine nucleotides on intracellular Ca2+ in human eosinophils: activation of purinergic P2Y receptors
10.1067/mai.2001.114658 · 2001 · External reference
P2X7 nucleotide receptor mediation of membrane pore formation and superoxide generation in human promyelocytes and neutrophils
10.4049/jimmunol.166.11.6754 · 2001 · External reference
Molecular mechanisms of thrombus formation in ischemic stroke: novel insights and targets for treatment
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The role of platelets in ischemic stroke
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