Research graph
References from Disease, Models, Variants and Altered Pathways—Journeying RGD Through the Magnifying Glass. Local targets link to admitted publications; unresolved targets remain external evidence.
Genetics of diabetes—are we missing the genes or the disease?
10.1016/j.mce.2013.04.002 · 2014 · External reference
Diabetes: a 21st century challenge
10.1016/s2213-8587(13)70112-8 · 2014 · External reference
10.1038/nrneph.2015.37
10.1038/nrneph.2015.37 · External reference
Role of non-coding RNAs in pancreatic beta-cell development and physiology
10.1111/apha.12285 · 2014 · External reference
Translational implications of the beta-cell epigenome in diabetes mellitus
10.1016/j.trsl.2014.03.002 · 2014 · External reference
The role of gut microbiota in the development of type 1, type2 diabetes mellitus and obesity
10.1007/s11154-015-9309-0 · 2015 · External reference
Cardiovascular safety profile of currently available diabetic drugs
2014 · External reference
Insulinotropic meglitinide analogues
10.1016/s0140-6736(01)06715-0 · 2001 · External reference
10.1007/s00125-013-2991-0
10.1007/s00125-013-2991-0 · External reference
Glucagon receptors
10.1007/s00018-008-7479-6 · 2008 · External reference
10.1152/physrev.00013.2014
10.1152/physrev.00013.2014 · External reference
Novel aspects of the molecular mechanisms of insulin secretion
10.1113/jphysiol.2008.155317 · 2008 · External reference
Pancreatic beta-cell identity, glucose sensing and control of insulin secretion
10.1042/bj20141384 · 2015 · External reference
Regulation of insulin receptor function
10.1007/s00018-007-6359-9 · 2007 · External reference
10.1038/nrm1837
10.1038/nrm1837 · External reference
10.1172/jci60016
10.1172/jci60016 · External reference
Neural regulation of pancreatic islet cell mass and function
10.1111/dom.12346 · 2014 · External reference
10.1152/ajpcell.00069.2014
10.1152/ajpcell.00069.2014 · External reference
Rho GTPases in insulin-stimulated glucose uptake
2014 · External reference
10.1016/j.bbamcr.2012.08.009
10.1016/j.bbamcr.2012.08.009 · External reference
10.1111/j.1365-201x.2004.01380.x
10.1111/j.1365-201x.2004.01380.x · External reference
10.1152/ajpendo.00091.2012
10.1152/ajpendo.00091.2012 · External reference
10.1146/annurev-biochem-060608-102511
10.1146/annurev-biochem-060608-102511 · External reference
10.1586/14789450.2013.820536
10.1586/14789450.2013.820536 · External reference
10.1002/iub.1017
10.1002/iub.1017 · External reference
10.1152/ajpendo.90604.2008
10.1152/ajpendo.90604.2008 · External reference
The updated RGD Pathway Portal utilizes increased curation efficiency and provides expanded pathway information
2012 · External reference
Unresolved reference
External reference
The pathway ontology—updates and applications
2014 · External reference
Disease pathways at the Rat Genome Database Pathway Portal: genes in context—a network approach to understanding the molecular mechanisms of disease
2014 · External reference
The Rat Genome Database 2015: genomic, phenotypic and environmental variations and disease
10.1093/nar/gku1026 · 2015 · External reference
PhenoMiner: quantitative phenotype curation at the rat genome database
10.1093/database/bat015 · 2013 · External reference
PhenoMiner: a quantitative phenotype database for the laboratory rat, Rattus norvegicus. Application in hypertension and renal disease
2015 · External reference
The clinical measurement, measurement method and experimental condition ontologies: expansion, improvements and new applications
2013 · External reference
The GK rat beta cell: a prototype for the diseased human beta-cell in type 2 diabetes?
10.1016/j.mce.2008.06.013 · 2009 · External reference
Pathophysiological and genetic characterization of the major diabetes locus in GK rats
10.2337/diabetes.48.12.2463 · 1999 · External reference
10.2337/diabetes.50.12.2737
10.2337/diabetes.50.12.2737 · External reference
Separately inherited defects in insulin exocytosis and beta-cell glucose metabolism contribute to type 2 diabetes
10.2337/db06-0796 · 2006 · External reference
High resolution quantitative train locus analysis reveals multiple diabetes susceptibility loci mapped to intervals <800kb in the species-conserved Niddm1i of the GK rat
10.1534/genetics.106.062208 · 2006 · External reference
Genomic landscape of rat strain and substrain variation
10.1186/s12864-015-1594-1 · 2015 · External reference
10.1016/j.cell.2013.06.040
10.1016/j.cell.2013.06.040 · External reference
Unresolved reference
External reference
10.1093/hmg/ddu359
10.1093/hmg/ddu359 · External reference
Role of pancreatic transcription factors in maintenance of mature beta-cell function
10.3390/ijms16036281 · 2015 · External reference
10.1111/j.2040-1124.2012.00199.x
10.1111/j.2040-1124.2012.00199.x · External reference
10.1016/j.tem.2014.03.008
10.1016/j.tem.2014.03.008 · External reference
10.1007/s11892-010-0149-8
10.1007/s11892-010-0149-8 · External reference
10.1016/j.gene.2013.09.105
10.1016/j.gene.2013.09.105 · External reference
10.1007/s00018-013-1551-6
10.1007/s00018-013-1551-6 · External reference
10.1016/j.tibs.2013.10.002
10.1016/j.tibs.2013.10.002 · External reference
Regulation of metabolism by long, non-coding RNA
10.3389/fgene.2014.00057 · 2014 · External reference
miRNAs as pharmacological targets in diabetes
10.1016/j.phrs.2013.06.005 · 2013 · External reference
MicroRNA and type 2 diabetes/obesity
10.1016/j.jgg.2011.11.007 · 2012 · External reference
miRGate: a curated database of human, mouse and rat miRNA-mRNA, targets
10.1093/database/bav035 · 2015 · External reference
Pancreatic islets plasticity: interspecies comparison of islet architecture and composition
10.4161/isl.2.3.11815 · 2010 · External reference
Functional implications of lncRNA in the pancreatic islets of Langerhans
2014 · External reference
10.1016/j.cmet.2012.08.010
10.1016/j.cmet.2012.08.010 · External reference
Unresolved reference
External reference
10.2217/epi.15.7
10.2217/epi.15.7 · External reference
10.1161/atvbaha.115.305041
10.1161/atvbaha.115.305041 · External reference
Hepatic cellular senescence pathway genes are induced through histone modifications in a diet-induced obese rat model
10.1152/ajpgi.00032.2011 · 2012 · External reference
Epigenomics and the microbiota
10.1177/0192623314553805 · 2014 · External reference
Innate inflammation in type 1 diabetes
2015 · External reference
10.1007/s00005-015-0332-3
10.1007/s00005-015-0332-3 · External reference
10.2337/db12-0365
10.2337/db12-0365 · External reference
Type 1 diabetes and autoimmunity
10.1297/cpe.23.99 · 2014 · External reference
Pancreatic beta-cell dedifferentiation as mechanism of diabetic beta-cell failure
10.1016/j.cell.2012.07.029 · 2012 · External reference
Discovery and fine-mapping of glycaemic and obesity-related trait loci using high-density imputation
10.1371/journal.pgen.1005230 · 2015 · External reference
