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References from Sharpening Precision Medicine by a Thorough Interrogation of Metabolic Individuality. Local targets link to admitted publications; unresolved targets remain external evidence.
Untargeted metabolomic analysis for the clinical screening of inborn errors of metabolism
2015 · External reference
Plasma metabolomic profiles enhance precision medicine for volunteers of normal health
2015 · External reference
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10.1016/j.cell.2012.02.009
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10.1016/j.cell.2014.02.012
10.1016/j.cell.2014.02.012 · External reference
10.1007/s00439-013-1331-2
10.1007/s00439-013-1331-2 · External reference
Systems genomics of metabolic phenotypes in wild-type Drosophila melanogaster
10.1534/genetics.114.163857 · 2014 · External reference
10.1126/science.aab2319
10.1126/science.aab2319 · External reference
10.1001/jama.2014.1717
10.1001/jama.2014.1717 · External reference
10.1038/nature11247
10.1038/nature11247 · External reference
Clinical application of whole-genome sequencing: proceed with care
10.1001/jama.2014.1718 · 2014 · External reference
10.1016/j.cmet.2012.12.007
10.1016/j.cmet.2012.12.007 · External reference
10.1111/cts.12131
10.1111/cts.12131 · External reference
10.1016/j.cell.2014.02.045
10.1016/j.cell.2014.02.045 · External reference
10.1517/17425255.2014.922954
10.1517/17425255.2014.922954 · External reference
10.1038/msb4100095
10.1038/msb4100095 · External reference
10.1038/nature10354
10.1038/nature10354 · External reference
10.1038/ng.2982
10.1038/ng.2982 · External reference
Improved drug therapy: triangulating phenomics with genomics and metabolomics
10.1186/s40246-014-0016-9 · 2014 · External reference
Metabolomic signatures for drug response phenotypes: pharmacometabolomics enables precision medicine
10.1002/cpt.134 · 2015 · External reference
10.1039/c2mb25167a
10.1039/c2mb25167a · External reference
The conservation and evolutionary modularity of metabolism
10.1186/gb-2009-10-6-r63 · 2009 · External reference
10.1016/j.cell.2012.02.032
10.1016/j.cell.2012.02.032 · External reference
10.1038/nature12752
10.1038/nature12752 · External reference
10.1016/j.cell.2013.03.004
10.1016/j.cell.2013.03.004 · External reference
Unresolved reference
1931 · External reference
Unresolved reference
1909 · External reference
Relationship among genotype, biochemical phenotype, and cognitive performance in females with phenylalanine hydroxylase deficiency: report from the Maternal Phenylketonuria Collaborative Study
10.1542/peds.104.2.258 · 1999 · External reference
10.1038/nature08494
10.1038/nature08494 · External reference
10.1126/science.1150021
10.1126/science.1150021 · External reference
Elevations of C14:1 and C14:2 plasma acylcarnitines in fasted children: A diagnostic dilemma
10.1016/j.jpeds.2015.10.045 · 2016 · External reference
Alpha-hydroxybutyrate is an early biomarker of insulin resistance and glucose intolerance in a nondiabetic population
10.1371/journal.pone.0010883 · 2010 · External reference
Uremic solutes and risk of end-stage renal disease in type 2 diabetes: metabolomic study
2014 · External reference
Novel biomarkers for pre-diabetes identified by metabolomics
10.1038/msb.2012.43 · 2012 · External reference
10.1038/nm.2307
10.1038/nm.2307 · External reference
Ethylene glycol monomethyl ether-induced toxicity is mediated through the inhibition of flavoprotein dehydrogenase enzyme family
10.1093/toxsci/kfq211 · 2010 · External reference
The dietary compound curcumin inhibits p300 histone acetyltransferase activity and prevents heart failure in rats
2008 · External reference
10.1158/0008-5472.can-08-2442
10.1158/0008-5472.can-08-2442 · External reference
Common genetic polymorphisms affect the human requirement for the nutrient choline
10.1096/fj.06-5734com · 2006 · External reference
Gut check: testing a role for the intestinal microbiome in human obesity
10.1126/scitranslmed.3000483 · 2009 · External reference
10.1016/j.cell.2013.11.024
10.1016/j.cell.2013.11.024 · External reference
Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection
2014 · External reference
10.1016/j.cmet.2014.11.008
10.1016/j.cmet.2014.11.008 · External reference
Gut-microbiota-metaboliteaxis in early renal function decline
10.1371/journal.pone.0134311 · 2015 · External reference
Association of synergistetes and cyclodipeptides with periodontitis
10.1177/0022034515594779 · 2015 · External reference
10.1016/j.cell.2015.02.047
10.1016/j.cell.2015.02.047 · External reference
Early infancy microbial and metabolic alterations affect risk of childhood asthma
10.1126/scitranslmed.aab2271 · 2015 · External reference
10.1016/j.cell.2014.06.020
10.1016/j.cell.2014.06.020 · External reference
Physiology. When metabolism and epigenetics converge
10.1126/science.1233423 · 2013 · External reference
10.1016/j.cell.2011.10.042
10.1016/j.cell.2011.10.042 · External reference
10.1038/nature14190
10.1038/nature14190 · External reference
10.1126/science.1226603
10.1126/science.1226603 · External reference
10.1126/science.1227166
10.1126/science.1227166 · External reference
Early metabolic markers of the development of dysglycemia and type 2 diabetes and their physiological significance
10.2337/db12-0707 · 2012 · External reference
An integrated clinico-metabolomic model improves prediction of death in sepsis
10.1126/scitranslmed.3005893 · 2013 · External reference
Metabolomics analysis reveals elevation of 3-indoxyl sulfate in plasma and brain during chemically-induced acute kidney injury in mice: investigation of nicotinic acid receptor agonists
10.1016/j.taap.2011.05.015 · 2011 · External reference
Metabolic disturbances associated with systemic lupus erythematosus
10.1371/journal.pone.0037210 · 2012 · External reference
10.1038/nrm3305
10.1038/nrm3305 · External reference
Rethinking the regulation of cellular metabolism
10.1101/sqb.2012.76.010496 · 2011 · External reference
10.1126/science.1199908
10.1126/science.1199908 · External reference
10.1161/hypertensionaha.115.05544
10.1161/hypertensionaha.115.05544 · External reference
A next generation multiscale view of inborn errors of metabolism
2015 · External reference
10.1016/j.ymgme.2015.04.008
10.1016/j.ymgme.2015.04.008 · External reference
10.2217/bmm.14.12
10.2217/bmm.14.12 · External reference
Association between rs12045440 polymorphism in the CAPZB intron and serum TSH concentrations in Chinese thyroid tumor patients
10.1155/2015/250542 · 2015 · External reference
Intron polymorphism in MYL1 gene is associated with individual cardiac trainability to endurance training in human
2015 · External reference