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References from Network analysis of human post-mortem microarrays reveals novel genes, microRNAs, and mechanistic scenarios of potential importance in fighting huntington's disease. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1002/ana.410270403
10.1002/ana.410270403 · External reference
10.1016/s0140-6736(03)13304-1
10.1016/s0140-6736(03)13304-1 · External reference
Genetics and neuropathology of Huntington's disease
10.1016/b978-0-12-381328-2.00014-6 · 2011 · External reference
The ubiquitin proteasome system in Huntington's disease and the spinocerebellar ataxias
10.1186/1471-2091-8-s1-s2 · 2007 · External reference
10.1111/j.1460-9568.2008.06310.x
10.1111/j.1460-9568.2008.06310.x · External reference
10.1111/j.1582-4934.2010.01010.x
10.1111/j.1582-4934.2010.01010.x · External reference
10.1038/nn.2528
10.1038/nn.2528 · External reference
10.1152/physrev.00041.2009
10.1152/physrev.00041.2009 · External reference
10.1038/35040009
10.1038/35040009 · External reference
10.1016/0006-8993(81)90853-2
10.1016/0006-8993(81)90853-2 · External reference
Cytochrome C and caspase-9 expression in Huntington's disease
10.1385/nmm:1:3:183 · 2002 · External reference
Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH
10.1038/nm0396-347 · 1996 · External reference
10.1046/j.1471-4159.2001.00033.x
10.1046/j.1471-4159.2001.00033.x · External reference
10.1371/journal.pbio.1001895
10.1371/journal.pbio.1001895 · External reference
Large-scale functional RNAi screen in C. elegans identifies genes that regulate the dysfunction of mutant polyglutamine neurons
10.1186/1471-2164-13-91 · 2012 · External reference
Brain-derived neurotrophic factor in Huntington disease
10.1016/s0006-8993(00)02237-x · 2000 · External reference
10.1016/s1474-4422(10)70245-3
10.1016/s1474-4422(10)70245-3 · External reference
10.1016/j.brainresrev.2008.07.007
10.1016/j.brainresrev.2008.07.007 · External reference
10.1016/j.freeradbiomed.2008.05.014
10.1016/j.freeradbiomed.2008.05.014 · External reference
10.1093/hmg/ddm133
10.1093/hmg/ddm133 · External reference
Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain
10.1093/hmg/11.17.1911 · 2002 · External reference
10.1097/nen.0b013e3181ea167f
10.1097/nen.0b013e3181ea167f · External reference
10.1093/hmg/ddq018
10.1093/hmg/ddq018 · External reference
Decreased expression of striatal signaling genes in a mouse model of Huntington's disease
10.1093/hmg/9.9.1259 · 2000 · External reference
10.1523/jneurosci.1658-03.2004
10.1523/jneurosci.1658-03.2004 · External reference
10.1073/pnas.0506375102
10.1073/pnas.0506375102 · External reference
10.1073/pnas.0509222102
10.1073/pnas.0509222102 · External reference
10.1046/j.1471-4159.2003.02105.x
10.1046/j.1471-4159.2003.02105.x · External reference
10.1172/jci46305
10.1172/jci46305 · External reference
10.1016/j.pharmthera.2010.07.008
10.1016/j.pharmthera.2010.07.008 · External reference
10.1093/hmg/dds040
10.1093/hmg/dds040 · External reference
A common gene expression signature in Huntington's disease patient brain regions
10.1186/s12920-014-0060-2 · 2014 · External reference
Huntington's disease and its therapeutic target genes: a global functional profile based on the HD Research Crossroads database
10.1186/1471-2377-12-47 · 2012 · External reference
Efficient key pathway mining: combining networks and OMICS data
10.1039/c2ib00133k · 2012 · External reference
A network view on schizophrenia related genes
2012 · External reference
10.5936/csbj.201304004 · Admitted local publication
Network topology analysis of post-mortem brain microarrays identifies more Alzheimer's related genes and MicroRNAs and points to novel routes for fighting with the disease
10.1371/journal.pone.0144052 · 2016 · External reference
Unresolved reference
External reference
10.1093/hmg/ddl013
10.1093/hmg/ddl013 · External reference
10.1093/biostatistics/4.2.249
10.1093/biostatistics/4.2.249 · External reference
10.1186/gb-2004-5-10-r80
10.1186/gb-2004-5-10-r80 · External reference
10.2202/1544-6115.1027
10.2202/1544-6115.1027 · External reference
10.1093/bioinformatics/btg290
10.1093/bioinformatics/btg290 · External reference
Pajek - program for large network analysis
1998 · External reference
10.1093/acprof:oso/9780199591756.001.0001
10.1093/acprof:oso/9780199591756.001.0001 · 2011 · External reference
DAVID: database for annotation, visualization, and integrated discovery
10.1186/gb-2003-4-5-p3 · 2003 · External reference
10.1038/nprot.2008.211
10.1038/nprot.2008.211 · External reference
10.1093/nar/gkn923
10.1093/nar/gkn923 · External reference
10.1093/nar/28.1.27
10.1093/nar/28.1.27 · External reference
CX3CL1 reduces neurotoxicity and microglial activation in a rat model of Parkinson's disease
10.1186/1742-2094-8-9 · 2011 · External reference
The soluble isoform of CX3CL1 is necessary for neuroprotection in a mouse model of Parkinson's disease
10.1523/jneurosci.0539-12.2012 · 2012 · External reference
Peroxisome-proliferator-activated receptor gamma coactivator 1 α contributes to dysmyelination in experimental models of Huntington's disease
10.1523/jneurosci.1291-11.2011 · 2011 · External reference
10.1073/pnas.1206506109
10.1073/pnas.1206506109 · External reference
An overview of animal prion diseases
10.1186/1743-422x-8-493 · 2011 · External reference
10.1086/324414
10.1086/324414 · External reference
Peroxiredoxin 6 promotes upregulation of the prion protein (PrP) in neuronal cells of prion-infected mice
10.1186/1478-811x-10-38 · 2012 · External reference
10.1523/jneurosci.2599-04.2004
10.1523/jneurosci.2599-04.2004 · External reference
10.1523/jneurosci.5504-10.2011
10.1523/jneurosci.5504-10.2011 · External reference
Leptin as a neuroprotective agent
10.1016/j.bbrc.2008.01.063 · 2008 · External reference
10.1038/sj.cdd.4401130
10.1038/sj.cdd.4401130 · External reference
10.1046/j.1471-4159.2000.0751085.x
10.1046/j.1471-4159.2000.0751085.x · External reference
10.1093/hmg/ddq160
10.1093/hmg/ddq160 · External reference
Epistasis between tau phosphorylation regulating genes (CDK5R1 and GSK-3beta) and Alzheimer's disease risk
10.1111/j.1600-0404.2008.01128.x · 2009 · External reference
10.1007/s00702-009-0240-y
10.1007/s00702-009-0240-y · External reference
Untangling the tau gene association with neurodegenerative disorders
10.1093/hmg/ddl190 · 2006 · External reference
10.1016/j.biocel.2010.07.016
10.1016/j.biocel.2010.07.016 · External reference
10.1074/jbc.272.13.8121
10.1074/jbc.272.13.8121 · External reference
Large potentials of small heat shock proteins
10.1152/physrev.00023.2010 · 2011 · External reference
Sex differences in a transgenic rat model of Huntington's disease: decreased 17beta-estradiol levels correlate with reduced numbers of DARPP32+ neurons in males
10.1093/hmg/ddn159 · 2008 · External reference
Age at onset in Huntington's disease: effect of line of inheritance and patient's sex
10.1136/jmg.28.8.515 · 1991 · External reference
Huntington's disease of the endocrine pancreas: insulin deficiency and diabetes mellitus due to impaired insulin gene expression
10.1006/nbdi.2002.0562 · 2002 · External reference
10.1016/j.neuron.2005.06.005
10.1016/j.neuron.2005.06.005 · External reference
10.1093/hmg/ddi443
10.1093/hmg/ddi443 · External reference
Glucose homeostasis in Huntington disease: abnormalities in insulin sensitivity and early-phase insulin secretion
10.1001/archneur.65.4.476 · 2008 · External reference
Adipose tissue dysfunction tracks disease progression in two Huntington's disease mouse models
10.1093/hmg/ddn428 · 2009 · External reference
10.1093/hmg/ddr127
10.1093/hmg/ddr127 · External reference
10.1002/emmm.201201546
10.1002/emmm.201201546 · External reference
Platform presentation—early defect of transforming growth factor β1 formation in Huntington's disease
10.1016/j.nurt.2009.09.025 · 2010 · External reference
10.1007/s00702-010-0430-7
10.1007/s00702-010-0430-7 · External reference
10.1038/nature09782
10.1038/nature09782 · External reference
10.1126/science.1059581
10.1126/science.1059581 · External reference
Role of brain-derived neurotrophic factor in Huntington's disease
10.1016/j.pneurobio.2007.01.003 · 2007 · External reference
10.1038/ng1362
10.1038/ng1362 · External reference
10.1126/science.275.5300.661
10.1126/science.275.5300.661 · External reference
Cellular automata approaches to biological modeling
10.1006/jtbi.1993.1007 · 1993 · External reference
Chan AWS. microRNA-128a dysregulation in transgenic Huntington's disease monkeys
10.1186/1756-6606-7-46 · 2014 · External reference
10.1016/j.drudis.2009.09.009
10.1016/j.drudis.2009.09.009 · External reference
MicroRNA-124 slows down the progression of Huntington's disease by promoting neurogenesis in the striatum
10.4103/1673-5374.156978 · 2015 · External reference
Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus
10.1097/wnr.0b013e3280148e8b · 2007 · External reference
10.1523/jneurosci.2390-08.2008
10.1523/jneurosci.2390-08.2008 · External reference
10.1016/j.pharmthera.2011.10.002
10.1016/j.pharmthera.2011.10.002 · External reference
10.1016/j.semcdb.2010.01.009
10.1016/j.semcdb.2010.01.009 · External reference
10.1016/j.yexcr.2008.06.002
10.1016/j.yexcr.2008.06.002 · External reference
10.1016/j.bbrc.2009.11.128
10.1016/j.bbrc.2009.11.128 · External reference
10.1073/pnas.0808263106
10.1073/pnas.0808263106 · External reference
Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells
10.1371/journal.pone.0008697 · 2010 · External reference
Differential expression of PTEN-targeting microRNAs miR-19a and miR-21 in Cowden syndrome
10.1016/j.ajhg.2008.04.005 · 2008 · External reference
Accumulation of tumor-suppressor PTEN in Alzheimer neurofibrillary tangles
10.1016/j.neulet.2009.12.078 · 2010 · External reference
MicroRNAs and deregulated gene expression networks in neurodegeneration
10.1016/j.brainres.2010.03.106 · 2010 · External reference
10.1371/journal.pone.0143563
10.1371/journal.pone.0143563 · External reference
10.1038/nn.3668
10.1038/nn.3668 · External reference
