Research graph
References from Biobetters From an Integrated Computational/Experimental Approach. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1002/med.20067
10.1002/med.20067 · External reference
Computational methods of studying the binding of toxins from venomous animals to biological ion channels
10.1152/physrev.00035.2012 · 2013 · External reference
10.4155/fmc.14.98
10.4155/fmc.14.98 · External reference
10.1002/prot.10115
10.1002/prot.10115 · External reference
10.1146/annurev.biophys.32.110601.142532
10.1146/annurev.biophys.32.110601.142532 · External reference
10.1002/(sici)1096-987x(19981115)19:14<1639::aid-jcc10>3.0.co;2-b
10.1002/(sici)1096-987x(19981115)19:14<1639::aid-jcc10>3.0.co;2-b · External reference
10.1002/jcc.21256
10.1002/jcc.21256 · External reference
10.1002/prot.21502
10.1002/prot.21502 · External reference
10.1021/ja026939x
10.1021/ja026939x · External reference
10.1002/prot.21723
10.1002/prot.21723 · External reference
10.1021/jm050362n
10.1021/jm050362n · External reference
Binding of organic cations to gramicidin: a channel studied with autodock and molecular dynamics simulations
10.1021/jp074228l · 2007 · External reference
Ligand binding to the voltage-gated Kv1.5 potassium channel in the open state–docking and computer simulations of a homology model
2007 · External reference
10.1002/prot.21706
10.1002/prot.21706 · External reference
10.1016/j.bpj.2008.12.3952
10.1016/j.bpj.2008.12.3952 · External reference
Developing a comparative docking protocol for the prediction of peptide selectivity profiles: investigation of potassium channel toxins
10.3390/toxins4020110 · 2012 · External reference
10.1002/jcc.20289
10.1002/jcc.20289 · External reference
VMD–visual molecular dynamics
10.1016/0263-7855(96)00018-5 · 1996 · External reference
All-atom empirical potential for molecular modeling and dynamics studies of proteins
10.1021/jp973084f · 1998 · External reference
Unresolved reference
1996 · External reference
Unresolved reference
2001 · External reference
10.1016/j.str.2011.10.002
10.1016/j.str.2011.10.002 · External reference
10.1146/annurev-biophys-042910-155245
10.1146/annurev-biophys-042910-155245 · External reference
10.1007/s12551-012-0084-9 · Admitted local publication
10.1016/j.bpj.2009.02.041
10.1016/j.bpj.2009.02.041 · External reference
10.1021/ar000033j
10.1021/ar000033j · External reference
10.1021/cr800551w
10.1021/cr800551w · External reference
10.1021/jp807701h
10.1021/jp807701h · External reference
Basic ingredients of free energy calculations
10.1002/jcc.21450 · 2010 · External reference
Towards accurate free energy calculations in ligand-protein binding studies
10.2174/092986710790514453 · 2010 · External reference
Can we use docking and scoring for hit-to-lead optimization?
10.1007/s10822-007-9165-4 · 2008 · External reference
10.1038/nrd3139
10.1038/nrd3139 · External reference
10.1021/jm801444x
10.1021/jm801444x · External reference
Absolute binding free energy calculations: on the accuracy of computational scoring of protein-ligand interactions
10.1002/prot.22687 · 2010 · External reference
Prediction of protein-ligand affinity by free energy simulations: assumptions, pitfalls and expectations
10.1007/s10822-010-9363-3 · 2011 · External reference
Alchemical free energy methods for drug discovery: progress and challenges
10.1016/j.sbi.2011.01.011 · 2011 · External reference
Perspective: alchemical free energy calculations in drug discovery
10.1063/1.4769292 · 2012 · External reference
The weighted histogram analysis method for free-energy calculations on biomolecules
10.1002/jcc.540130812 · 1992 · External reference
Accurate determination of the binding free energy for KcsA-charybdotoxin complex from the potential of mean force calculations
10.1016/j.bpj.2011.03.052 · 2011 · External reference
10.3390/md11030848
10.3390/md11030848 · External reference
10.1063/1.1651473
10.1063/1.1651473 · External reference
Potential of mean force calculations of ligand binding to ion channels from Jarzynski's equality and umbrella sampling
10.1063/1.2904461 · 2008 · External reference
A potent and selective peptide blocker of the Kv1.3 channel: prediction from free-energy simulations and experimental confirmation
10.1371/journal.pone.0078712 · 2013 · External reference
Determination of antibody affinity by ELISA
10.1016/s0165-022x(03)00145-3 · 2003 · External reference
Surface plasmon resonance (SPR) biosensors in pharmaceutical analysis
10.1080/10408347.2014.881250 · 2015 · External reference
10.1016/j.jim.2005.04.016
10.1016/j.jim.2005.04.016 · External reference
Unresolved reference
2010 · External reference
Strategies for the assessment of protein aggregates in pharmaceutical biotech product development
10.1007/s11095-010-0297-1 · 2011 · External reference
Unresolved reference
2015 · External reference
10.1007/978-0-387-46312-4
10.1007/978-0-387-46312-4 · 2006 · External reference
Tryptophan-tryptophan energy transfer and classification of tryptophan residues in proteins: therapeutic monoclonal antibody as a model
10.1007/s10895-010-0715-0 · 2010 · External reference
10.1080/07391102.2000.10506651
10.1080/07391102.2000.10506651 · External reference
A screening tool for therapeutic monoclonal antibodies: identifying the most stable protein and its best formulation based on thioflavin T binding
10.1002/biot.201100366 · 2012 · External reference
New methods for measuring macromolecular interactions in solution via static light scattering: basic methodology and application to nonassociating and self-associating proteins
10.1016/j.ab.2004.09.045 · 2005 · External reference
Kinetics of thermal aggregation of tobacco mosaic virus coat protein
10.1023/a:1015589926728 · 2002 · External reference
Evaluation of a non-Arrhenius model for therapeutic monoclonal antibody aggregation
10.1002/jps.22493 · 2011 · External reference
10.1021/cr078234p
10.1021/cr078234p · External reference
10.1126/science.280.5360.69
10.1126/science.280.5360.69 · External reference
10.1016/j.toxicon.2011.07.016
10.1016/j.toxicon.2011.07.016 · External reference
10.1021/jp300639x
10.1021/jp300639x · External reference
10.1074/jbc.m410055200
10.1074/jbc.m410055200 · External reference
Free energy simulations of binding of HsTx1 toxin to Kv1 potassium channels: the basis of Kv1.3/Kv1.1 selectivity
10.1021/jp410950h · 2014 · External reference
A potent and Kv1.3-selective analogue of the scorpion toxin HsTX1 as a potential therapeutic for autoimmune diseases
10.1038/srep04509 · 2014 · External reference
Enabling noninvasive systemic delivery of the Kv1.3-blocking peptide HsTX1[R14A] via the buccal mucosa
10.1016/j.xphs.2016.05.008 · 2016 · External reference
10.1016/j.toxicon.2010.12.003
10.1016/j.toxicon.2010.12.003 · External reference
α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structure
10.1021/ja206408q · 2011 · External reference
10.1021/jm200839a
10.1021/jm200839a · External reference
10.1371/journal.pone.0152169
10.1371/journal.pone.0152169 · External reference
10.4161/19420862.2015.989042
10.4161/19420862.2015.989042 · External reference
The state-of-play and future of antibody therapeutics
2016 · External reference
10.1016/j.jmb.2009.06.028
10.1016/j.jmb.2009.06.028 · External reference
10.1073/pnas.0904191106
10.1073/pnas.0904191106 · External reference
10.1002/wcms.1088
10.1002/wcms.1088 · External reference
