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References from Hyperglycemia aggravates microenvironment hypoxia and promotes the metastatic ability of pancreatic cancer. Local targets link to admitted publications; unresolved targets remain external evidence.
10.3322/caac.21442
10.3322/caac.21442 · External reference
Pancreatic cancer incidence and mortality patterns in China
2015 · External reference
Value of surgical resection and timing of therapy in patients with pancreatic cancer at high risk for positive margins
10.1136/esmoopen-2017-000282 · 2018 · External reference
Systematic review of pancreatic cancer epidemiology in Asia-Pacific region: major patterns in GLOBACON 2012
2017 · External reference
Diabetes mellitus and obesity as risk factors for pancreatic cancer
2017 · External reference
Association of elevated risk of pancreatic cancer in diabetic patients: a systematic review and meta-analysis
10.3892/ol.2017.5586 · 2017 · External reference
Hyperglycemia promotes the epithelial-mesenchymal transition of pancreatic cancer via hydrogen peroxide
10.1155/2016/5190314 · 2016 · External reference
Hyperglycemic tumor microenvironment induces perineural invasion in pancreatic cancer
10.1080/15384047.2015.1040952 · 2015 · External reference
Hyperglycemia induces cellular hypoxia through production of mitochondrial ROS Followed by suppression of aquaporin-1
10.1371/journal.pone.0158619 · 2016 · External reference
Histone deacetylase inhibition restores expression of hypoxia-inducible protein NDRG1 in pancreatic cancer
10.1097/mpa.0000000000000982 · 2018 · External reference
Hypoxia induces oncogene yes-associated protein 1 nuclear translocation to promote pancreatic ductal adenocarcinoma invasion via epithelial-mesenchymal transition
2017 · External reference
10.1016/j.yexcr.2010.02.019
10.1016/j.yexcr.2010.02.019 · External reference
10.1006/meth.2001.1262
10.1006/meth.2001.1262 · External reference
Effects of loading on chondrocyte hypoxia, HIF-1alpha and VEGF in the mandibular condylar cartilage of young rats
10.1111/ocr.12212 · 2018 · External reference
Effects of transition metals on the expression of the erythropoietin gene: further evidence that the oxygen sensor is a heme protein
10.1006/bbrc.1996.0865 · 1996 · External reference
Copper depletion inhibits CoCl2-induced aggressive phenotype of MCF-7 cells via downregulation of HIF-1 and inhibition of Snail/Twist-mediated epithelial-mesenchymal transition
10.1038/srep12410 · 2015 · External reference
10.3322/caac.21387
10.3322/caac.21387 · External reference
10.1158/0008-5472.can-14-0155
10.1158/0008-5472.can-14-0155 · External reference
10.1002/ijc.30599
10.1002/ijc.30599 · External reference
10.1016/j.critrevonc.2016.11.003
10.1016/j.critrevonc.2016.11.003 · External reference
High glucose promotes pancreatic cancer cell proliferation via the induction of EGF expression and transactivation of EGFR
10.1371/journal.pone.0027074 · 2011 · External reference
10.1007/s11010-010-0617-0
10.1007/s11010-010-0617-0 · External reference
Hydrogen peroxide mediates hyperglycemia-induced invasive activity via ERK and p38 MAPK in human pancreatic cancer
10.18632/oncotarget.5045 · 2015 · External reference
Hypoxia induces TWIST-activated epithelial-mesenchymal transition and proliferation of pancreatic cancer cells in vitro and in nude mice
10.1016/j.canlet.2016.09.027 · 2016 · External reference
The impact of hypoxia in pancreatic cancer invasion and metastasis
2014 · External reference
10.1016/j.pan.2014.06.008
10.1016/j.pan.2014.06.008 · External reference
Hypoxia inducible factor 1 (HIF-1) recruits macrophage to activate pancreatic stellate cells in pancreatic ductal adenocarcinoma
2016 · External reference
High glucose activates HIF-1-mediated signal transduction in glomerular mesangial cells through a carbohydrate response element binding protein
10.1038/ki.2010.99 · 2010 · External reference
10.1007/s00018-011-0731-5
10.1007/s00018-011-0731-5 · External reference