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References from Computational drug repurposing for inflammatory bowel disease using genetic information. Local targets link to admitted publications; unresolved targets remain external evidence.
The epidemiology and risk factors of inflammatory bowel disease
2015 · External reference
10.1038/labinvest.2013.9
10.1038/labinvest.2013.9 · External reference
Inflammatory bowel disease: pathogenesis
10.3748/wjg.v20.i1.91 · 2014 · External reference
10.1016/j.bpg.2014.04.002
10.1016/j.bpg.2014.04.002 · External reference
Chapter11: genome-wide association studies
2012 · External reference
10.1038/ng.3760
10.1038/ng.3760 · External reference
repoDB: a new standard for drug repositioning validation
10.1038/sdata.2017.29 · 2017 · External reference
Emerging therapies for inflammatory bowel disease
10.1007/s12325-018-0795-9 · 2018 · External reference
Drug repositioning in inflammatory bowel disease based on genetic information
10.1097/mib.0000000000000912 · 2016 · External reference
Computational prediction of drug-target interactions using chemogenomic approaches: an empirical survey
2018 · External reference
10.1038/ng.3359
10.1038/ng.3359 · External reference
Gene2drug: a computational tool for pathway-based rational drug repositioning
10.1093/bioinformatics/btx800 · 2017 · External reference
Unresolved reference
External reference
10.1073/pnas.0506580102
10.1073/pnas.0506580102 · External reference
10.1126/science.1132939
10.1126/science.1132939 · External reference
Aminopeptidase N (CD13) regulates tumour necrosis factor-α-induced apoptosis in human neutrophils
10.1074/jbc.m511277200 · 2006 · External reference
The role of pathophysiological relevance of membrane transporter Pep T1 in intestinal inflammation and inflammatory bowel disease
10.1152/ajpgi.00477.2011 · 2011 · External reference
Inflammatory bowel disease and endothelin-1
10.1097/00002727-200504000-00013 · 2005 · External reference
Pregnane X receptor as a target for treatment of inflammatory bowel disorders
10.1016/j.tips.2012.03.003 · 2012 · External reference
10.1177/1756283x12446158
10.1177/1756283x12446158 · External reference
Protein kinases are potential targets to treat inflammatory bowel disease
10.4292/wjgpt.v5.i4.209 · 2014 · External reference
Inhibition of N-terminal ATPase on HSP90 attenuates colitis through enhanced Treg function
2013 · External reference
Hydroxylase inhibition regulates inflammation-induced intestinal fibrosis through the suppression of ERK-mediated TGF- ß1 signaling
10.1152/ajpgi.00229.2016 · 2016 · External reference
Transglutaminase 2 is dispensable but required for the survival of mice in dextran sulfate sodium-induced colitis
10.1038/emm.2016.95 · 2016 · External reference
Pyruvate carboxylase activates the RIG-I-like receptor-mediated antiviral immune response by targeting the MAVS signalosome
2016 · External reference
Why isn't cefadroxil used more often?
10.2146/ajhp150841 · 2016 · External reference
An anticholinergic burden score for German prescribers: score development
10.1186/s12877-018-0929-6 · 2018 · External reference
Management of digoxin toxicity
10.18773/austprescr.2016.006 · 2016 · External reference
Differential interactions of rifabutin with human and bacterial membranes: implication for its therapeutic and toxic effects
10.1021/jm301116j · 2013 · External reference
10.1016/j.jconrel.2015.09.022
10.1016/j.jconrel.2015.09.022 · External reference
Efficacy and safety of amphotericin B lipid-based formulations-a systematic review and meta-analysis
10.1111/myc.12585 · 2017 · External reference
10.1053/j.gastro.2007.10.012
10.1053/j.gastro.2007.10.012 · External reference
Lanatoside C sensitizes glioblastoma cells to tumor necrosis factor-related apoptosis-inducing ligand and induces an alternative cell death pathway
10.1093/neuonc/nor067 · 2011 · External reference
Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool
10.1186/1471-2105-14-128 · 2013 · External reference
Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
10.1093/nar/gkw377 · 2016 · External reference
DrugBank 5.0: a major update to the DrugBank database for 2018
10.1093/nar/gkx1037 · 2018 · External reference
DGIdb 3.0: a redesign and expansion of the drug-gene interaction database
10.1093/nar/gkx1143 · 2017 · External reference
Aminopeptidase N (CD13) as a target for cancer chemotherapy
10.1111/j.1349-7006.2010.01826.x · 2011 · External reference
Inflammatory bowel diseases: multiple benefits from therapy with dipeptidyl and alanyl-aminopeptidase inhibitors
10.2741/2960 · 2008 · External reference
10.1172/jci11830
10.1172/jci11830 · External reference
A comprehensive in vitro and in silico analysis of antibiotics that activate pregnane X receptor and induce CYP3A4 in liver and intestine
10.1124/dmd.108.020701 · 2008 · External reference
10.1016/j.bcp.2018.02.023
10.1016/j.bcp.2018.02.023 · External reference
Apoptosis and inflammation: role of adipokines in inflammatory bowel disease
10.1038/ctg.2010.1 · 2010 · External reference
Lanatoside C, a cardiac glycoside, acts through protein kinase C∂ to cause apoptosis of human hepatocellular carcinoma cells
2017 · External reference
Protein kinase C∂ activates RelA/p65 and nuclear factor- κB signaling in response to tumor necrosis factor-α
10.1158/0008-5472.can-08-4786 · 2009 · External reference
Gastroenterology today: between certainties and news
10.23736/s1121-421x.18.02465-0 · 2018 · External reference
10.1016/j.gene.2014.03.046
10.1016/j.gene.2014.03.046 · External reference
10.1016/j.mam.2015.12.004
10.1016/j.mam.2015.12.004 · External reference
Reducing the toxicity of amphotericin B by encapsulation using methoxy poly(ethylene glycol)-b-poly(L-glutamic acid-co-L-phenylalanine)
10.1039/c8bm00506k · 2018 · External reference
10.1002/med.21385
10.1002/med.21385 · External reference
Amphotericin B inhibits the serum-induced expression of tissue transglutaminase in murine peritoneal macrophages
10.4049/jimmunol.136.11.4206 · 1986 · External reference
Effects of amphotericin B on the glucose metabolism in saccharomyces cerevisiae cells. Studies by 13C-, 1H-NMR and biochemical methods
10.1111/j.1432-1033.1991.tb15908.x · 1991 · External reference
10.1002/ibd.22958
10.1002/ibd.22958 · External reference
Explore small molecule-induced genome-wide transcriptional profiles for novel inflammatory bowel disease drug
2016 · External reference