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References from Computational Simulations Identified Two Candidate Inhibitors of Cdk5/p25 to Abrogate Tau-associated Neurological Disorders. Local targets link to admitted publications; unresolved targets remain external evidence.
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TFP5 peptide, derived from Cdk5-activating cofactor p35, provides neuroprotection in early-stage of adult ischemic stroke
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Optimization of 6,6-dimethyl pyrrolo[3,4-c]pyrazoles: identification of PHA-793887, a potent CDK inhibitor suitable for intravenous dosing
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10.1002/(sici)1096-987x(199709)18:12<1463::aid-jcc4>3.0.co;2-h
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Unresolved reference
External reference
Unresolved reference
External reference
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10.3390/molecules23112824 · 2018 · External reference
Defining Cdk5 ligand chemical space with small molecule inhibitors of Tau phosphorylation
2005 · External reference
Synthesis and structure-activity relationship of 4-(1,3-benzothiazol-2-yl)-thiophene-2-sulfonamides as cyclin-dependent kinase 5 (cdk5)/p25 inhibitors
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