Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Research graph
References from Insights into a Crucial Role of TRIP13 in Human Cancer. Local targets link to admitted publications; unresolved targets remain external evidence.
Mode of interaction of TRIP13 AAA-ATPase with the Mad2-binding protein p31comet and with mitotic checkpoint complexes
10.1073/pnas.1515358112 · 2015 · External reference
10.1007/s00412-015-0516-y
10.1007/s00412-015-0516-y · External reference
10.15252/embj.201797291
10.15252/embj.201797291 · External reference
Mechanistic insight into TRIP13-catalyzed Mad2 structural transition and spindle checkpoint silencing
10.1038/s41467-017-02012-2 · 2017 · External reference
Mechanism for remodelling of the cell cycle checkpoint protein MAD2 by the ATPase TRIP13
10.1038/s41586-018-0281-1 · 2018 · External reference
10.18632/oncotarget.14957
10.18632/oncotarget.14957 · External reference
10.1038/nrm2163
10.1038/nrm2163 · External reference
10.1016/j.cub.2012.10.006
10.1016/j.cub.2012.10.006 · External reference
10.1038/nature10896
10.1038/nature10896 · External reference
A centrosomal route for cancer genome instability
10.1038/ncb2978 · 2014 · External reference
10.1038/nature08803
10.1038/nature08803 · External reference
Mad2 and BubR1 modulates tumourigenesis and paclitaxel response in MKN45 gastric cancer cells
10.4161/15384101.2014.962952 · 2014 · External reference
10.1042/bst0381698
10.1042/bst0381698 · External reference
10.1073/pnas.0408454102
10.1073/pnas.0408454102 · External reference
Telomeres, chromosome instability and cancer
10.1093/nar/gkl303 · 2006 · External reference
10.1034/j.1600-065x.2003.00060.x
10.1034/j.1600-065x.2003.00060.x · External reference
10.1016/j.ccr.2012.12.001
10.1016/j.ccr.2012.12.001 · External reference
10.1074/jbc.m114.585315
10.1074/jbc.m114.585315 · External reference
10.1038/ng.3883
10.1038/ng.3883 · External reference
10.1038/ng1861
10.1038/ng1861 · External reference
10.1016/j.cell.2007.08.048
10.1016/j.cell.2007.08.048 · External reference
Identification of novel mitosis regulators through data mining with human centromere/kinetochore proteins as group queries
10.1186/1471-2121-13-15 · 2012 · External reference
Identification of a MAD2-binding protein, CMT2, and its role in mitosis
10.1093/emboj/cdf659 · 2002 · External reference
10.1038/sj.emboj.7601033
10.1038/sj.emboj.7601033 · External reference
10.1016/j.semcdb.2011.03.008
10.1016/j.semcdb.2011.03.008 · External reference
10.1016/j.cub.2015.08.051
10.1016/j.cub.2015.08.051 · External reference
10.1002/jcp.25042
10.1002/jcp.25042 · External reference
10.1126/science.1244508
10.1126/science.1244508 · External reference
10.1083/jcb.200102093
10.1083/jcb.200102093 · External reference
10.1038/nrm3132
10.1038/nrm3132 · External reference
10.1016/j.tibs.2013.03.004
10.1016/j.tibs.2013.03.004 · External reference
TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switching
2015 · External reference
Disassembly of mitotic checkpoint complexes by the joint action of the AAA-ATPase TRIP13 and p31(comet)
10.1073/pnas.1412901111 · 2014 · External reference
10.1016/j.cub.2005.01.038
10.1016/j.cub.2005.01.038 · External reference
10.1016/j.sbi.2007.08.011
10.1016/j.sbi.2007.08.011 · External reference
10.1016/j.cub.2004.05.053
10.1016/j.cub.2004.05.053 · External reference
Dynamics of centromere and kinetochore proteins; implications for checkpoint signaling and silencing
2004 · External reference
10.1038/emboj.2009.186
10.1038/emboj.2009.186 · External reference
10.1038/nature21384
10.1038/nature21384 · External reference
The influence of catalysis on mad2 activation dynamics
10.1371/journal.pbio.1000010 · 2009 · External reference
Unattached kinetochores catalyze production of an anaphase inhibitor that requires a Mad2 template to prime Cdc20 for BubR1 binding
10.1016/j.devcel.2008.11.005 · 2009 · External reference
TRIP13 regulates both the activation and inactivation of the spindle-assembly checkpoint
10.1016/j.celrep.2016.01.001 · 2016 · External reference
10.1083/jcb.201301130
10.1083/jcb.201301130 · External reference
10.1073/pnas.1001875107
10.1073/pnas.1001875107 · External reference
Roles of different pools of the mitotic checkpoint complex and the mechanisms of their disassembly
10.1073/pnas.1308928110 · 2013 · External reference
TRIP13 functions in the establishment of the spindle assembly checkpoint by replenishing O-MAD2
10.1016/j.celrep.2018.01.027 · 2018 · External reference
10.1038/s41467-018-06774-1
10.1038/s41467-018-06774-1 · External reference
10.1371/journal.pgen.0030130
10.1371/journal.pgen.0030130 · External reference
Genetic evidence that synaptonemal complex axial elements govern recombination pathway choice in mice
10.1534/genetics.111.130674 · 2011 · External reference
Spo11 and the formation of DNA double-Strand breaks in meiosis
10.1007/7050_2007_026 · 2008 · External reference
10.1371/journal.pgen.1005017
10.1371/journal.pgen.1005017 · External reference
10.1126/science.1117468
10.1126/science.1117468 · External reference
10.1016/j.cub.2006.10.069
10.1016/j.cub.2006.10.069 · External reference
10.1016/s0092-8674(00)80741-2
10.1016/s0092-8674(00)80741-2 · External reference
Drosophila PCH2 is required for a pachytene checkpoint that monitors double-strand-break-independent events leading to meiotic crossover formation
10.1534/genetics.108.093112 · 2009 · External reference
Chromosome axis defects induce a checkpoint-mediated delay and interchromosomal effect on crossing over during Drosophila meiosis
10.1371/journal.pgen.1001059 · 2010 · External reference
10.1016/j.molcel.2012.07.029
10.1016/j.molcel.2012.07.029 · External reference
10.1016/j.molcel.2014.12.027
10.1016/j.molcel.2014.12.027 · External reference
10.1534/genetics.111.129031
10.1534/genetics.111.129031 · External reference
10.1371/journal.pgen.1002351
10.1371/journal.pgen.1002351 · External reference
10.1016/j.devcel.2014.09.013
10.1016/j.devcel.2014.09.013 · External reference
10.1016/j.cell.2011.07.003
10.1016/j.cell.2011.07.003 · External reference
10.1371/journal.pone.0085687
10.1371/journal.pone.0085687 · External reference
Mouse TRIP13/PCH2 is required for recombination and normal higher-order chromosome structure during meiosis
10.1371/journal.pgen.1001062 · 2010 · External reference
10.1371/journal.pgen.1006845
10.1371/journal.pgen.1006845 · External reference
TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer
10.1038/ncomms5527 · 2014 · External reference
10.1146/annurev-genet-110711-155540
10.1146/annurev-genet-110711-155540 · External reference
10.1158/0008-5472.can-08-4833
10.1158/0008-5472.can-08-4833 · External reference
10.1172/jci59954
10.1172/jci59954 · External reference
10.1093/nar/gkx247
10.1093/nar/gkx247 · External reference
10.1101/gad.314351.118
10.1101/gad.314351.118 · External reference
10.1093/carcin/bgq133
10.1093/carcin/bgq133 · External reference
10.1016/j.tibs.2010.09.005
10.1016/j.tibs.2010.09.005 · External reference
10.1016/j.toxlet.2015.12.004
10.1016/j.toxlet.2015.12.004 · External reference
TRIP13-deficient tubular epithelial cells are susceptible to apoptosis following acute kidney injury
10.1038/srep43196 · 2017 · External reference
p53 haploinsufficiency and functional abnormalities in multiple myeloma
10.1038/leu.2014.102 · 2014 · External reference
10.1038/nrc1714
10.1038/nrc1714 · External reference
10.1016/j.semcdb.2011.03.002
10.1016/j.semcdb.2011.03.002 · External reference
10.1038/ng1449
10.1038/ng1449 · External reference
10.1158/0008-5472.can-12-1991
10.1158/0008-5472.can-12-1991 · External reference
Overexpression of BUB1B contributes to progression of prostate cancer and predicts poor outcome in patients with prostate cancer
2016 · External reference
Overexpression of BUBR1 is associated with chromosomal instability in bladder cancer
10.1016/j.cancergencyto.2006.11.012 · 2007 · External reference
The spindle-assembly checkpoint, aneuploidy, and gastrointestinal cancer
10.1056/nejme1008017 · 2010 · External reference
Role of CCT chaperonin in the disassembly of mitotic checkpoint complexes
10.1073/pnas.1620451114 · 2017 · External reference
TRIP13 is expressed in colorectal cancer and promotes cancer cell invasion
10.3892/ol.2016.5332 · 2016 · External reference
10.18632/oncotarget.16038
10.18632/oncotarget.16038 · External reference
Thyroid hormone receptor interactor 13 (TRIP13) overexpression associated with tumor progression and poor prognosis in lung adenocarcinoma
10.1016/j.bbrc.2018.03.129 · 2018 · External reference
TRIP13 is a predictor for poor prognosis and regulates cell proliferation, migration and invasion in prostate cancer
10.1016/j.ijbiomac.2018.09.168 · 2018 · External reference
TRIP13 promotes tumor growth and is associated with poor prognosis in colorectal cancer
10.1038/s41419-018-0434-z · 2018 · External reference
10.1038/embor.2012.61
10.1038/embor.2012.61 · External reference
10.4161/23723548.2014.970484
10.4161/23723548.2014.970484 · External reference
10.1038/nrc2781
10.1038/nrc2781 · External reference
Low MAD2 expression levels associate with reduced progression-free survival in patients with high-grade serous epithelial ovarian cancer
10.1002/path.3035 · 2012 · External reference
Targeting the phosphatidylinositol 3-kinase/AKT pathway for the treatment of multiple myeloma
10.2174/0929867321666140601204513 · 2014 · External reference
10.1038/ncomms8769
10.1038/ncomms8769 · External reference
10.1038/onc.2009.300
10.1038/onc.2009.300 · External reference
10.1073/pnas.0401994101
10.1073/pnas.0401994101 · External reference
10.1371/journal.pone.0002994
10.1371/journal.pone.0002994 · External reference
DNA-damage related genes and clinical outcome in hormone receptor positive breast cancer
10.18632/oncotarget.10886 · 2017 · External reference
A meta-analysis of gene expression data identifies a molecular signature characteristic for tumor-stage mycosis fungoides
10.1038/jid.2012.117 · 2012 · External reference
Identification of markers of prostate cancer progression using candidate gene expression
10.1038/bjc.2011.490 · 2012 · External reference
A 19-gene expression signature as a predictor of survival in colorectal cancer
10.1186/s12920-016-0218-1 · 2016 · External reference
Five gene probes carry most of the discriminatory power of the 70-gene risk model in multiple myeloma
10.1038/leu.2014.232 · 2014 · External reference
10.1016/j.cancergencyto.2007.12.004
10.1016/j.cancergencyto.2007.12.004 · External reference
Unresolved reference
2018 · External reference
LncRNA TINCR is associated with clinical progression and serves as tumor suppressive role in prostate cancer
10.2147/cmar.s170526 · 2018 · External reference