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References from FOXO3 on the Road to Longevity: Lessons From SNPs and Chromatin Hubs. Local targets link to admitted publications; unresolved targets remain external evidence.
Aging is not programmed: genetic pseudo-program is a shadow of developmental growth
10.4161/cc.27188 · 2013 · External reference
10.18632/aging.100591
10.18632/aging.100591 · External reference
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10.1093/gerona/gls068
10.1093/gerona/gls068 · External reference
10.1007/s00439-013-1342-z
10.1007/s00439-013-1342-z · External reference
Aging genetics and aging
2011 · External reference
10.1016/s0092-8674(00)80595-4
10.1016/s0092-8674(00)80595-4 · External reference
The fork head domain: a novel DNA binding motif of eukaryotic transcription factors?
10.1016/0092-8674(90)90439-l · 1990 · External reference
10.1006/dbio.2002.0780
10.1006/dbio.2002.0780 · External reference
10.1038/onc.2008.27
10.1038/onc.2008.27 · External reference
10.1038/nrm2190
10.1038/nrm2190 · External reference
10.1038/onc.2008.24
10.1038/onc.2008.24 · External reference
10.1038/366461a0
10.1038/366461a0 · External reference
10.1093/genetics/143.3.1207
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10.1126/science.278.5341.1319
10.1126/science.278.5341.1319 · External reference
10.1038/40194
10.1038/40194 · External reference
Sensory control of dauer larva formation in Caenorhabditis elegans
10.1002/cne.901980305 · 1981 · External reference
10.1038/nature02549
10.1038/nature02549 · External reference
10.1126/science.1098219
10.1126/science.1098219 · External reference
10.1073/pnas.0400093101
10.1073/pnas.0400093101 · External reference
10.1126/science.1086336
10.1126/science.1086336 · External reference
10.1038/onc.2008.21
10.1038/onc.2008.21 · External reference
Recent advances in understanding the role of FOXO3
10.12688/f1000research.15258.1 · 2018 · External reference
The role of insulin and IGF-1 signaling in longevity
10.1007/s00018-004-4297-y · 2005 · External reference
10.1038/nature01036
10.1038/nature01036 · External reference
10.1126/science.1069004
10.1126/science.1069004 · External reference
10.1126/science.1068712
10.1126/science.1068712 · External reference
The AMPK-FoxO3A axis as a target for cancer treatment
10.4161/cc.9.6.11035 · 2010 · External reference
10.1007/s00018-012-1244-6
10.1007/s00018-012-1244-6 · External reference
SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression
10.7150/ijbs.4.291 · 2008 · External reference
Mitochondrial localization of the forkhead box class O transcription factor FOXO3a in brain
10.1111/jnc.12133 · 2013 · External reference
Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy
10.1038/s41419-018-0336-0 · 2018 · External reference
Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity
10.1073/pnas.1003540107 · 2010 · External reference
10.1073/pnas.0801030105
10.1073/pnas.0801030105 · External reference
Genetic variation in FOXO3 is associated with self-rated health in a population-based sample of older individuals
10.1093/gerona/gly021 · 2018 · External reference
10.1111/acel.12295
10.1111/acel.12295 · External reference
10.1038/cdd.2009.36
10.1038/cdd.2009.36 · External reference
10.1111/igc.0b013e3181c8ca12
10.1111/igc.0b013e3181c8ca12 · External reference
Inhibition of p38alpha unveils an AMPK-FoxO3A axis linking autophagy to cancer-specific metabolism
10.4161/auto.5.7.9252 · 2009 · External reference
IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a
10.1016/s0092-8674(04)00302-2 · 2004 · External reference
Low expression of Foxo3a is associated with poor prognosis in ovarian cancer patients
10.1080/07357900802146204 · 2009 · External reference
10.1371/journal.pone.0070746
10.1371/journal.pone.0070746 · External reference
FOXO3a nuclear localisation is associated with good prognosis in luminal-like breast cancer
10.1007/s10549-010-1161-z · 2011 · External reference
Decreased expression of the FOXO3a gene is associated with poor prognosis in primary gastric adenocarcinoma patients
10.1371/journal.pone.0078158 · 2013 · External reference
FoxO3a confers cetuximab resistance in RAS wild-type metastatic colorectal cancer through c-Myc
2016 · External reference
10.7314/apjcp.2015.16.4.1443
10.7314/apjcp.2015.16.4.1443 · External reference
10.1038/sj.onc.1209086
10.1038/sj.onc.1209086 · External reference
10.1172/jci23126
10.1172/jci23126 · External reference
10.1136/gutjnl-2016-312940
10.1136/gutjnl-2016-312940 · External reference
10.1371/journal.pone.0194225
10.1371/journal.pone.0194225 · External reference
Increased myogenic and protein turnover signaling in skeletal muscle of chronic obstructive pulmonary disease patients with sarcopenia
2017 · External reference
10.1016/j.stemcr.2014.02.002
10.1016/j.stemcr.2014.02.002 · External reference
10.1016/j.devcel.2010.03.008
10.1016/j.devcel.2010.03.008 · External reference
10.1038/s41467-017-02183-y
10.1038/s41467-017-02183-y · External reference
10.1038/onc.2011.35
10.1038/onc.2011.35 · External reference
FOXO3 longevity interactome on chromosome 6
10.1111/acel.12625 · 2017 · External reference
Rolling circle amplification for scoring single nucleotide polymorphisms
10.1081/ncn-100002453 · 2001 · External reference
10.1016/j.cell.2016.09.018
10.1016/j.cell.2016.09.018 · External reference
Association of the FOXO3A locus with extreme longevity in a southern Italian centenarian study
10.1089/rej.2008.0827 · 2009 · External reference
10.1073/pnas.0809594106
10.1073/pnas.0809594106 · External reference
10.1093/hmg/ddp459
10.1093/hmg/ddp459 · External reference
Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data
10.1111/j.1474-9726.2010.00627.x · 2010 · External reference
10.1111/j.1474-9726.2009.00493.x
10.1111/j.1474-9726.2009.00493.x · External reference
Association between FOXO3A gene polymorphisms and human longevity: a meta-analysis
10.4103/1008-682x.123673 · 2014 · External reference
GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy
10.1093/gerona/glu166 · 2015 · External reference
FOXO3 variants are beneficial for longevity in southern Chinese living in the Red River Basin: a case-control study and meta-analysis
10.1038/srep09852 · 2015 · External reference
10.1093/ajh/hpv171
10.1093/ajh/hpv171 · External reference
Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits
10.1111/acel.12490 · 2016 · External reference
Longevity-associated FOXO3 genotype and its impact on coronary artery disease mortality in Japanese, whites, and blacks: a prospective study of three American populations
2017 · External reference
Characterization of the rs2802292 SNP identifies FOXO3A as a modifier locus predicting cancer risk in patients with PJS and PHTS hamartomatous polyposis syndromes
10.1186/1471-2407-14-661 · 2014 · External reference
10.1093/gerona/gls067
10.1093/gerona/gls067 · External reference
The FOXO3A rs2802292 G-allele associates with improved peripheral and hepatic insulin sensitivity and increased skeletal muscle-FOXO3A mRNA expression in twins
10.1210/jc.2010-0881 · 2011 · External reference
10.1038/35066075
10.1038/35066075 · External reference
10.1146/annurev-genom-091212-153515
10.1146/annurev-genom-091212-153515 · External reference
10.1038/nsmb1324
10.1038/nsmb1324 · External reference
10.1093/hmg/ddw216
10.1093/hmg/ddw216 · External reference
10.1038/nrg3458
10.1038/nrg3458 · External reference
10.1016/j.molcel.2013.01.038
10.1016/j.molcel.2013.01.038 · External reference
10.1126/science.1067799
10.1126/science.1067799 · External reference
10.1371/journal.pgen.1001343
10.1371/journal.pgen.1001343 · External reference
10.1023/a:1024922626726
10.1023/a:1024922626726 · External reference
10.1002/1521-1878(200007)22:7<657::aid-bies8>3.0.co;2-2
10.1002/1521-1878(200007)22:7<657::aid-bies8>3.0.co;2-2 · External reference
10.1126/science.1181369
10.1126/science.1181369 · External reference
10.1038/nature11082
10.1038/nature11082 · External reference
10.1016/j.gde.2010.02.002
10.1016/j.gde.2010.02.002 · External reference
10.1016/j.tig.2014.02.006
10.1016/j.tig.2014.02.006 · External reference
10.1101/gad.399506
10.1101/gad.399506 · External reference
Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression
10.1038/ng.2416 · 2012 · External reference
10.1016/j.molcel.2007.11.020
10.1016/j.molcel.2007.11.020 · External reference
10.1093/nar/gky331
10.1093/nar/gky331 · External reference
10.1242/jcs.132605
10.1242/jcs.132605 · External reference
10.1101/gad.894801
10.1101/gad.894801 · External reference
10.1074/jbc.m602454200
10.1074/jbc.m602454200 · External reference
Fine structure analyses of the Drosophila and Saccharomyces heat shock factor--heat shock element interactions
10.1093/nar/22.2.167 · 1994 · External reference
10.1016/s0092-8674(03)00310-6
10.1016/s0092-8674(03)00310-6 · External reference
Chromatin looping defines expression of TAL1, its flanking genes, and regulation in T-ALL
10.1182/blood-2013-02-483875 · 2013 · External reference
10.1016/j.febslet.2004.07.006
10.1016/j.febslet.2004.07.006 · External reference
Systems-level analysis of human aging genes shed new light on mechanisms of aging
2016 · External reference
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10.1023/a:1005427919188 · External reference
10.1016/s0891-5849(02)01356-4
10.1016/s0891-5849(02)01356-4 · External reference
Rapid activation of nuclear factor-κB by 17β-Estradiol and selective Estrogen receptor modulators: pathways mediating cellular protection
10.1097/shk.0b013e31825da754 · 2012 · External reference
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10.2174/138920206779315737 · External reference
Why females live longer than males: control of longevity by sex hormones
2005 · External reference
The estrogen receptor α is the key regulator of the bifunctional role of FoxO3a transcription factor in breast cancer motility and invasiveness
10.4161/cc.26421 · 2013 · External reference
10.1128/mcb.00824-09
10.1128/mcb.00824-09 · External reference
10.1038/onc.2013.384
10.1038/onc.2013.384 · External reference
10.1242/dev.02667
10.1242/dev.02667 · External reference
Constitutively active Foxo3 in oocytes preserves ovarian reserve in mice
10.1038/ncomms2861 · 2013 · External reference
Regulation of ovarian primordial follicle assembly and development by estrogen and progesterone: endocrine model of follicle assembly
10.1210/en.2002-0131 · 2003 · External reference
Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans
10.1073/pnas.0308291101 · 2004 · External reference
10.1016/j.cmet.2007.08.011
10.1016/j.cmet.2007.08.011 · External reference
10.1093/gerona/glv057
10.1093/gerona/glv057 · External reference
FOXO3 and exceptional longevity: insights from Hydra to humans
10.1016/bs.ctdb.2017.10.001 · 2018 · External reference
Regulatory effects of curcumin on lipid accumulation in monocytes/macrophages
10.1002/jcb.23411 · 2012 · External reference
10.1158/0008-5472.can-06-4327
10.1158/0008-5472.can-06-4327 · External reference
