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References from DNA Supercoiling: an Ancestral Regulator of Gene Expression in Pathogenic Bacteria?. Local targets link to admitted publications; unresolved targets remain external evidence.
Genome scale patterns of supercoiling in a bacterial chromosome
10.1038/ncomms11055 · 2016 · External reference
10.1093/nar/gky1222
10.1093/nar/gky1222 · External reference
10.3390/microorganisms7030081
10.3390/microorganisms7030081 · External reference
10.1038/nrmicro1088
10.1038/nrmicro1088 · External reference
10.1007/s12551-016-0205-y
10.1007/s12551-016-0205-y · External reference
The structure of DNA
10.1101/sqb.1953.018.01.020 · 1953 · External reference
10.1016/j.gde.2013.10.013
10.1016/j.gde.2013.10.013 · External reference
10.1093/nar/gkp032
10.1093/nar/gkp032 · External reference
10.1016/j.celrep.2015.11.034
10.1016/j.celrep.2015.11.034 · External reference
10.1038/nrmicro2261
10.1038/nrmicro2261 · External reference
10.1002/1521-1878(200008)22:8<738::aid-bies7>3.0.co;2-5
10.1002/1521-1878(200008)22:8<738::aid-bies7>3.0.co;2-5 · External reference
Identification of DNA topoisomerases involved in immediate and transient DNA relaxation induced by heat shock in Escherichia coli
10.1007/bf00583895 · 1994 · External reference
Thermoregulation in Yersinia enterocolitica is coincident with changes in DNA supercoiling
10.1111/j.1365-2958.1994.tb01008.x · 1994 · External reference
10.1111/1462-2920.12198
10.1111/1462-2920.12198 · External reference
Changes in DNA supertwist as a response of Bacillus subtilis towards different kinds of stress
10.1111/j.1574-6968.1995.tb07926.x · 1995 · External reference
Increase in negative supercoiling of plasmid DNA in Escherichia coli exposed to cold shock
10.1046/j.1365-2958.1997.2181582.x · 1997 · External reference
The influence of DNA topology on the environmental regulation of a pH-regulated locus in Salmonella typhimurium
10.1111/j.1365-2958.1993.tb00905.x · 1993 · External reference
Bacterial regulon evolution: distinct responses and roles for the identical OmpR proteins of Salmonella Typhimurium and Escherichia coli in the acid stress response
10.1371/journal.pgen.1004215 · 2014 · External reference
Negative supercoiling of DNA by gyrase is inhibited in Salmonella enterica serovar Typhimurium during adaptation to acid stress
10.1111/mmi.13911 · 2018 · External reference
Chromosomal “stress-response” domains govern the spatiotemporal expression of the bacterial virulence program
10.1128/mbio.00353-15 · 2015 · External reference
10.1128/jb.173.12.3914-3917.1991
10.1128/jb.173.12.3914-3917.1991 · External reference
10.1016/0092-8674(88)90470-9
10.1016/0092-8674(88)90470-9 · External reference
The nucleoid-associated proteins H-NS and FIS modulate the DNA supercoiling response of the pel genes, the major virulence factors in the plant pathogen bacterium Dickeya dadantii
10.1093/nar/gks014 · 2012 · External reference
10.1007/bf00299136
10.1007/bf00299136 · External reference
10.1099/00221287-148-2-381
10.1099/00221287-148-2-381 · External reference
Escherichia coli response to hydrogen peroxide: a role for DNA supercoiling, topoisomerase I and Fis
10.1046/j.1365-2958.2000.01805.x · 2000 · External reference
Bacterial DNA supercoiling and [ATP]/[ADP]. Changes associated with a transition to anaerobic growth
1991 · External reference
DNA supercoiling is differentially regulated by environmental factors and FIS in Escherichia coli and Salmonella enterica
10.1111/j.1365-2958.2011.07560.x · 2011 · External reference
10.1128/jb.169.10.4499-4506.1987
10.1128/jb.169.10.4499-4506.1987 · External reference
10.1146/annurev.genet.36.032902.111815
10.1146/annurev.genet.36.032902.111815 · External reference
Biochemical basis of E. coli topoisomerase I relaxation activity reduction by nonenzymatic lysine acetylation
10.3390/ijms19051439 · 2018 · External reference
10.1016/j.chembiol.2010.04.012
10.1016/j.chembiol.2010.04.012 · External reference
The transcriptome of Streptococcus pneumoniae induced by local and global changes in supercoiling
10.3389/fmicb.2017.01447 · 2017 · External reference
10.1073/pnas.200365097
10.1073/pnas.200365097 · External reference
10.1038/nature18959
10.1038/nature18959 · External reference
Long-term experimental evolution in Escherichia coli. XII. DNA topology as a key target of selection
10.1534/genetics.104.035717 · 2005 · External reference
10.1016/j.cels.2016.04.015
10.1016/j.cels.2016.04.015 · External reference
10.1111/j.1365-2958.2011.07718.x
10.1111/j.1365-2958.2011.07718.x · External reference
Genomic analysis of the regulatory elements and links with intrinsic DNA structural properties in the shrunken genome of Buchnera
10.1186/1471-2164-14-73 · 2013 · External reference
Analysis of pleiotropic transcriptional profiles: a case study of DNA Gyrase inhibition
10.1371/journal.pgen.0020152 · 2006 · External reference
10.1101/gr.401003
10.1101/gr.401003 · External reference
Homeostatic regulation of supercoiling sensitivity coordinates transcription of the bacterial genome
10.1038/sj.embor.7400729 · 2006 · External reference
Genomic transcriptional response to loss of chromosomal supercoiling in Escherichia coli
10.1186/gb-2004-5-11-r87 · 2004 · External reference
Clinically relevant mutant DNA gyrase alters supercoiling, changes the transcriptome, and confers multidrug resistance
10.1128/mbio.00273-13 · 2013 · External reference
Bacterial genome architecture shapes global transcriptional regulation by DNA supercoiling
10.1093/nar/gkz300 · 2019 · External reference
10.1101/gr.157701
10.1101/gr.157701 · External reference
The genome of Streptococcus pneumoniae is organized in topology-reacting gene clusters
10.1093/nar/gkq106 · 2010 · External reference
An increase in negative supercoiling in bacteria reveals topology-reacting gene clusters and a homeostatic response mediated by the DNA topoisomerase I gene
2016 · External reference
Altering gene expression by aminocoumarins: the role of DNA supercoiling in Staphylococcus aureus
10.1186/1471-2164-15-291 · 2014 · External reference
Transcriptional responses of Bacillus subtillis and thuringiensis to antibiotics and anti-tumour drugs
2009 · External reference
Transcriptional response of Streptomyces coelicolor to rapid chromosome relaxation or long-term supercoiling imbalance
2019 · External reference
10.1074/jbc.m406796200
10.1074/jbc.m406796200 · External reference
DNA supercoiling regulates the stress-inducible expression of genes in the cyanobacterium Synechocystis
10.1039/b903022k · 2009 · External reference
10.1073/pnas.0912673106
10.1073/pnas.0912673106 · External reference
10.1016/j.gde.2005.02.007
10.1016/j.gde.2005.02.007 · External reference
Dissecting the logical types of network control in gene expression profiles
10.1186/1752-0509-2-18 · 2008 · External reference
10.1016/j.tim.2007.12.006
10.1016/j.tim.2007.12.006 · External reference
10.1016/s0168-9525(02)02650-1
10.1016/s0168-9525(02)02650-1 · External reference
Temperature dependence of the DNA double helix at the nanoscale: structure, elasticity, and fluctuations
10.1016/j.bpj.2013.09.004 · 2013 · External reference
10.1093/nar/gkt308
10.1093/nar/gkt308 · External reference
Twist-DNA: computing base-pair and bubble opening probabilities in genomic superhelical DNA
10.1093/bioinformatics/btt415 · 2013 · External reference
DNA dynamics play a role as a basal transcription factor in the positioning and regulation of gene transcription initiation
10.1093/nar/gkp1084 · 2010 · External reference
Promoter sequence for stringent control of bacterial ribonucleic acid synthesis
10.1128/jb.141.2.973-976.1980 · 1980 · External reference
10.1006/jmbi.2000.3780
10.1006/jmbi.2000.3780 · External reference
10.1016/s0022-2836(03)00727-7
10.1016/s0022-2836(03)00727-7 · External reference
Mechanism of transcription initiation and promoter escape by E. coli RNA polymerase
10.1073/pnas.1618675114 · 2017 · External reference
Effect of supercoiling on the abortive initiation kinetics of the RNA-I promoter of ColE1 plasmid DNA
10.1016/s0021-9258(18)90844-6 · 1984 · External reference
10.1021/bi030110t
10.1021/bi030110t · External reference
10.1016/0092-8674(83)90140-x
10.1016/0092-8674(83)90140-x · External reference
Inhibition of the gyrA promoter by transcription-coupled DNA supercoiling in Escherichia coli
10.1038/s41598-018-33089-4 · 2018 · External reference
Regulation of the gyr operon of mycobacterium tuberculosis by overlapping promoters, DNA topology, and reiterative transcription
10.1016/j.bbrc.2018.05.067 · 2018 · External reference
Integration of two essential virulence modulating signals at the Erwinia chrysanthemi pel gene promoters: a role for Fis in the growth-phase regulation
10.1111/j.1365-2958.2007.06010.x · 2007 · External reference
10.1111/j.1365-2958.1992.tb01358.x
10.1111/j.1365-2958.1992.tb01358.x · External reference
Axial distortion as a sensor of supercoil changes: a molecular model for the homeostatic regulation of DNA gyrase
10.1007/bf02717907 · 2001 · External reference
10.1126/science.1235441
10.1126/science.1235441 · External reference
10.15252/msb.20159000
10.15252/msb.20159000 · External reference
10.1093/nar/gky382
10.1093/nar/gky382 · External reference
10.1111/1462-2920.13838
10.1111/1462-2920.13838 · External reference
10.1093/bioinformatics/btx634
10.1093/bioinformatics/btx634 · External reference
Regulation of bacterial DNA supercoiling: plasmid linking numbers vary with growth temperature
10.1073/pnas.81.13.4046 · 1984 · External reference
10.1093/nar/28.8.1838
10.1093/nar/28.8.1838 · External reference
PecS is a global regulator of the symptomatic phase in the phytopathogenic bacterium Erwinia chrysanthemi 3937
10.1128/jb.00553-08 · 2008 · External reference
10.3390/ijms150712335
10.3390/ijms150712335 · External reference
Site-specific insertion and deletion mutants in the mer promoter-operator region of Tn501; the nineteen base-pair spacer is essential for normal induction of the promoter by MerR
10.1093/nar/18.17.5157 · 1990 · External reference
10.1038/sj.embor.7400898
10.1038/sj.embor.7400898 · External reference
General transfer matrix formalism to calculate DNA–protein–drug binding in gene regulation: application to OR operator of phage λ
10.1093/nar/gkm268 · 2007 · External reference
10.1093/nar/gkr141
10.1093/nar/gkr141 · External reference
10.1093/nar/gky478
10.1093/nar/gky478 · External reference
10.1103/physrevlett.93.108108
10.1103/physrevlett.93.108108 · External reference
10.1073/pnas.0500983102
10.1073/pnas.0500983102 · External reference
A fundamental regulatory mechanism operating through OmpR and DNA topology controls expression of Salmonella pathogenicity Islands SPI-1 and SPI-2
10.1371/journal.pgen.1002615 · 2012 · External reference
10.1371/journal.pcbi.1002484
10.1371/journal.pcbi.1002484 · External reference
10.1038/nsmb.1372
10.1038/nsmb.1372 · External reference
10.1016/0092-8674(85)90316-2
10.1016/0092-8674(85)90316-2 · External reference
10.1128/mbio.01442-14
10.1128/mbio.01442-14 · External reference
Supercoiling of the DNA template during transcription
10.1073/pnas.84.20.7024 · 1987 · External reference
10.1016/j.cell.2014.05.038
10.1016/j.cell.2014.05.038 · External reference
10.1126/science.1070919
10.1126/science.1070919 · External reference
10.1371/journal.pcbi.1003785
10.1371/journal.pcbi.1003785 · External reference
Stochastic model of supercoiling-dependent transcription
10.1103/physrevlett.117.018101 · 2016 · External reference
10.1016/j.bpj.2019.04.023
10.1016/j.bpj.2019.04.023 · External reference
10.1038/nsmb.2517
10.1038/nsmb.2517 · External reference
10.1371/journal.pgen.1006754
10.1371/journal.pgen.1006754 · External reference
Transcription-coupled DNA supercoiling dictates the chromosomal arrangement of bacterial genes
10.1093/nar/gkw007 · 2016 · External reference
10.1371/journal.pone.0155740
10.1371/journal.pone.0155740 · External reference
DNA supercoiling-dependent transcriptional coupling between the divergently transcribed promoters of the ilvYC operon of Escherichia coli is proportional to promoter strengths and transcript lengths
10.1046/j.1365-2958.2001.02249.x · 2001 · External reference
10.1016/0092-8674(95)90433-6
10.1016/0092-8674(95)90433-6 · External reference
A promoter relay mechanism for sequential gene activation
10.1128/jb.180.3.626-633.1998 · 1998 · External reference
10.1101/gad.1207504
10.1101/gad.1207504 · External reference
10.1093/nar/gkv709
10.1093/nar/gkv709 · External reference
10.1534/g3.114.016139
10.1534/g3.114.016139 · 2015 · External reference
Role of global and local topology in the regulation of gene expression in Streptococcus pneumoniae
10.1371/journal.pone.0101574 · 2014 · External reference
10.1088/1478-3975/aab4ac
10.1088/1478-3975/aab4ac · External reference
10.1128/cmr.17.1.14-56.2004
10.1128/cmr.17.1.14-56.2004 · External reference
10.1111/1462-2920.13611
10.1111/1462-2920.13611 · External reference
10.1016/j.mib.2010.10.003
10.1016/j.mib.2010.10.003 · External reference
Virulence gene regulation in Shigella
10.1128/ecosalplus.8.9.3 · 2004 · External reference
From ingestion to colonization: the influence of the host environment on regulation of the LEE encoded type III secretion system in enterohaemorrhagic Escherichia coli
2015 · External reference
DNA supercoiling and environmental regulation of virulence gene expression in Shigella flexneri
10.1038/344789a0 · 1990 · External reference
Transcriptional regulation of the espGenes of Enterohemorrhagic Escherichia coli
10.1128/jb.181.11.3409-3418.1999 · 1999 · External reference
Supercoiling of an excised genomic island represses effector gene expression to prevent activation of host resistance
10.1111/mmi.14111 · 2018 · External reference
10.1128/iai.01094-07
10.1128/iai.01094-07 · External reference
10.1128/jb.174.16.5211-5218.1992
10.1128/jb.174.16.5211-5218.1992 · External reference
10.1007/bf00425824
10.1007/bf00425824 · External reference
10.1128/aem.68.9.4209-4215.2002
10.1128/aem.68.9.4209-4215.2002 · External reference
Protein A gene expression is regulated by DNA supercoiling which is modified by the ArlS-ArlR two-component system of Staphylococcus aureus
10.1099/mic.0.27194-0 · 2004 · External reference
10.1128/aac.01706-13
10.1128/aac.01706-13 · External reference
10.1016/j.jmb.2019.02.029
10.1016/j.jmb.2019.02.029 · External reference
10.1093/gbe/evw299
10.1093/gbe/evw299 · External reference
Transcriptional start site turnover in the evolution of bacterial paralogous genes - the pelE-pelD virulence genes in Dickeya
10.1111/febs.13921 · 2016 · External reference
A polymer model of bacterial supercoiled DNA including structural transitions of the double helix
2019 · External reference