Research graph
References from Klebsiella pneumoniae capsule polysaccharide as a target for therapeutics and vaccines. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
2013 · External reference
Will 10 million people die a year due to antimicrobial resistance by 2050?
10.1371/journal.pmed.1002184 · 2016 · External reference
Pandrug resistance (PDR), extensive drug resistance (XDR), and multidrug resistance (MDR) among gram-negative bacilli: need for international harmonization in terminology
10.1086/528867 · 2008 · External reference
Successful treatment of pan-resistant Klebsiella pneumoniae pneumonia and bacteraemia with a combination of high-dose tigecycline and colistin
10.1099/jmm.0.023010-0 · 2010 · External reference
Community-acquired versus nosocomial Klebsiella pneumoniae bacteremia: clinical features, treatment outcomes, and clinical implication of antimicrobial resistance
10.3346/jkms.2006.21.5.816 · 2006 · External reference
Unresolved reference
2006 · External reference
Carbapenemase-producing Klebsiella pneumoniae: molecular and genetic decoding
10.1016/j.tim.2014.09.003 · 2014 · External reference
10.1016/s1473-3099(13)70190-7
10.1016/s1473-3099(13)70190-7 · External reference
Extended-spectrum beta-lactamase-producing Enterobacteriaceae: an emerging public-health concern
10.1016/s1473-3099(08)70041-0 · 2008 · External reference
Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae
10.1128/aac.45.4.1151-1161.2001 · 2001 · External reference
Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India
10.1128/aac.00774-09 · 2009 · External reference
Worldwide diversity of Klebsiella pneumoniae that produce beta-lactamase blaKPC-2 gene
10.3201/eid1609.091389 · 2010 · External reference
Molecular epidemiology of KPC-producing Klebsiella pneumoniae isolates in the United States: clonal expansion of multilocus sequence type 258
10.1128/aac.00126-09 · 2009 · External reference
Multicenter clinical and molecular epidemiological analysis of bacteremia due to carbapenem-resistant Enterobacteriaceae (CRE) in the CRE epicenter of the United States
10.1128/aac.02349-16 · 2017 · External reference
Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae: a review of epidemiological and clinical aspects
10.1517/14712598.2012.681369 · 2012 · External reference
Notes from the field: pan-resistant New Delhi metallo-beta-lactamase-producing Klebsiella pneumoniae - Washoe County, Nevada, 2016
10.15585/mmwr.mm6601a7 · 2017 · External reference
Treatment of Klebsiella pneumoniae carbapenemase (KPC) infections: a review of published case series and case reports
10.1186/1476-0711-11-32 · 2012 · External reference
A review on colistin nephrotoxicity
10.1007/s00228-015-1865-4 · 2015 · External reference
Colistin versus ceftazidime-avibactam in the treatment of infections due to carbapenem-resistant Enterobacteriaceae
10.1093/cid/cix783 · 2018 · External reference
Ceftazidime-avibactam for treatment of carbapenem-resistant Enterobacteriaceae bacteremia
10.1093/cid/ciw491 · 2016 · External reference
Clinical outcomes, drug toxicity, and emergence of ceftazidime-avibactam resistance among patients treated for carbapenem-resistant Enterobacteriaceae infections
10.1093/cid/ciw636 · 2016 · External reference
Emergence of ceftazidime-avibactam resistance due to plasmid-borne
10.1128/aac.02097-16 · 2017 · External reference
Unresolved reference
2014 · External reference
A NET outcome
2012 · External reference
10.3389/fimmu.2015.00262
10.3389/fimmu.2015.00262 · External reference
10.3389/fimmu.2015.00257
10.3389/fimmu.2015.00257 · External reference
10.1016/j.cell.2016.03.017
10.1016/j.cell.2016.03.017 · External reference
10.1128/mmbr.00078-15
10.1128/mmbr.00078-15 · External reference
10.1194/jlr.r800060-jlr200
10.1194/jlr.r800060-jlr200 · External reference
10.1038/nrmicro2266
10.1038/nrmicro2266 · External reference
Deciphering tissue-induced Klebsiella pneumoniae lipid A structure
10.1073/pnas.1508820112 · 2015 · External reference
10.1177/09680519050110030201
10.1177/09680519050110030201 · External reference
Biosynthesis of lipopolysaccharide O-antigens
10.1016/s0966-842x(00)88917-9 · 1995 · External reference
10.1128/jcm.37.1.56-62.1999
10.1128/jcm.37.1.56-62.1999 · External reference
Both clades of the epidemic KPC-producing Klebsiella pneumoniae clone ST258 share a modified galactan O-antigen type
10.1016/j.ijmm.2015.12.002 · 2016 · External reference
Immune stealth-driven O2 serotype prevalence and potential for therapeutic antibodies against multidrug resistant Klebsiella pneumoniae
10.1038/s41467-017-02223-7 · 2017 · External reference
10.1128/iai.55.11.2741-2746.1987
10.1128/iai.55.11.2741-2746.1987 · External reference
10.1128/iai.54.1.85-89.1986
10.1128/iai.54.1.85-89.1986 · External reference
10.1128/iai.61.3.852-860.1993
10.1128/iai.61.3.852-860.1993 · External reference
10.1128/iai.60.6.2529-2535.1992
10.1128/iai.60.6.2529-2535.1992 · External reference
10.1128/iai.59.6.2006-2011.1991
10.1128/iai.59.6.2006-2011.1991 · External reference
Genetic analysis of capsular polysaccharide synthesis gene clusters in 79 capsular types of Klebsiella spp
10.1038/srep15573 · 2015 · External reference
wzi gene sequencing, a rapid method for determination of capsular type for Klebsiella strains
10.1128/jcm.01924-13 · 2013 · External reference
Identification of capsular types in carbapenem-resistant Klebsiella pneumoniae strains by wzc sequencing and implications for capsule depolymerase treatment
10.1128/aac.03560-14 · 2015 · External reference
Capsular polysaccharide synthesis regions in Klebsiella pneumoniae serotype K57 and a new capsular serotype
10.1128/jcm.01716-07 · 2008 · External reference
10.1073/pnas.1321364111
10.1073/pnas.1321364111 · External reference
Importance of clonal complex 258 and IncF
2017 · External reference
Identification of Klebsiella capsule synthesis loci from whole genome data
2016 · External reference
10.1099/mic.0.029017-0
10.1099/mic.0.029017-0 · External reference
The relationship between insusceptibility to phagocytosis and virulence of certain Klebsiella pneumoniae strains
10.1093/infdis/103.2.157 · 1958 · External reference
10.1016/s1473-3099(12)70205-0
10.1016/s1473-3099(12)70205-0 · External reference
10.1128/iai.62.10.4495-4499.1994
10.1128/iai.62.10.4495-4499.1994 · External reference
Antibody-mediated killing of carbapenem-resistant ST258 Klebsiella pneumoniae by human neutrophils
10.1128/mbio.00297-18 · 2018 · External reference
10.1128/iai.70.5.2583-2590.2002
10.1128/iai.70.5.2583-2590.2002 · External reference
10.1179/2047773215y.0000000030
10.1179/2047773215y.0000000030 · External reference
K-antigen-specific, but not O-antigen-specific natural human serum antibodies promote phagocytosis of Klebsiella pneumoniae
10.1016/s0928-8244(02)00459-5 · 2003 · External reference
Survival of carbapenem-resistant Klebsiella pneumoniae sequence type 258 in human blood
10.1128/aac.02533-16 · 2017 · External reference
10.1128/iai.45.1.139-142.1984
10.1128/iai.45.1.139-142.1984 · External reference
10.1093/infdis/151.4.665
10.1093/infdis/151.4.665 · External reference
10.1128/iai.60.5.1771-1778.1992
10.1128/iai.60.5.1771-1778.1992 · External reference
10.1016/0882-4010(88)90020-4
10.1016/0882-4010(88)90020-4 · External reference
Novel, broadly reactive anticapsular antibodies against carbapenem-resistant Klebsiella pneumoniae protect from infection
2018 · External reference
Production and characterization of a human hyperimmune intravenous immunoglobulin against Pseudomonas aeruginosa and Klebsiella Species
10.1093/infdis/163.5.1055 · 1991 · External reference
Immunoprophylaxis against Klebsiella and Pseudomonas aeruginosa infections
10.1093/infdis/174.3.537 · 1996 · External reference
10.1128/iai.62.4.1282-1288.1994
10.1128/iai.62.4.1282-1288.1994 · External reference
10.1128/iai.65.5.1754-1760.1997
10.1128/iai.65.5.1754-1760.1997 · External reference
O antigen seroepidemiology of Klebsiella clinical isolates and implications for immunoprophylaxis of Klebsiella infections
10.1016/j.vaccine.2003.11.026 · 2004 · External reference
The diversity of Klebsiella pneumoniae surface polysaccharides
2016 · External reference
10.1038/s41590-018-0106-2
10.1038/s41590-018-0106-2 · External reference
10.1128/iai.54.2.403-407.1986
10.1128/iai.54.2.403-407.1986 · External reference
10.1016/0769-2625(88)90066-9
10.1016/0769-2625(88)90066-9 · External reference
10.1128/jcm.26.11.2257-2261.1988
10.1128/jcm.26.11.2257-2261.1988 · External reference
10.1016/s0264-410x(94)80054-4
10.1016/s0264-410x(94)80054-4 · External reference
10.1016/0264-410x(86)90092-7
10.1016/0264-410x(86)90092-7 · External reference
10.1016/j.coi.2011.03.004
10.1016/j.coi.2011.03.004 · External reference
10.1038/nrd3012
10.1038/nrd3012 · External reference
Antibody to capsular polysaccharides of Streptococcus pneumoniae: prevalence, persistence, and response to revaccination
10.1093/clinids/17.1.66 · 1993 · External reference
Combined schedules of pneumococcal conjugate and polysaccharide vaccines: is hyporesponsiveness an issue?
10.1016/s1473-3099(07)70210-4 · 2007 · External reference
10.1002/anie.201700964
10.1002/anie.201700964 · External reference
Considerations for the design of antibody-based therapeutics
2019 · External reference
Human monoclonal antibodies: the benefits of humanization
10.1007/978-1-4939-8958-4_1 · 2019 · External reference
10.1016/j.coi.2015.06.014
10.1016/j.coi.2015.06.014 · External reference
Vectored immunoprophylaxis: an emerging adjunct to traditional vaccination
10.1186/s40794-017-0046-0 · 2017 · External reference
The capsule regulatory network of Klebsiella pneumoniae defined by density-TraDISort
10.1128/mbio.01863-18 · 2018 · External reference
Risk factors and clinical impact of Klebsiella pneumoniae carbapenemase-producing K. pneumoniae
10.1086/648451 · 2009 · External reference
10.1111/j.1469-0691.2011.03478.x
10.1111/j.1469-0691.2011.03478.x · External reference
