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References from Bioinformatics and computational approaches for analyzing patient-derived disease models in cancer research. Local targets link to admitted publications; unresolved targets remain external evidence.
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10.15252/embj.2019101654 · External reference
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10.1016/j.molmed.2017.02.007
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Put to the test: organoid-based testing becomes a clinical tool
10.1038/nm0717-796 · 2017 · External reference
10.4161/rdis.27112
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10.1038/nm.3954
10.1038/nm.3954 · External reference
A comprehensive human gastric cancer Organoid Biobank captures tumor subtype heterogeneity and enables therapeutic screening
2018 · External reference
Oral cavity squamous cell carcinoma xenografts retain complex genotypes and intertumor molecular heterogeneity
10.1016/j.celrep.2018.07.058 · 2018 · External reference
A living biobank of breast cancer organoids captures disease heterogeneity
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Organoid cultures recapitulate esophageal adenocarcinoma heterogeneity providing a model for clonality studies and precision therapeutics
10.1038/s41467-018-05190-9 · 2018 · External reference
Whole genomes define concordance of matched primary, xenograft, and organoid models of pancreas cancer
10.1371/journal.pcbi.1006596 · 2019 · External reference
Patient-derived xenografts undergo mouse-specific tumor evolution
10.1038/ng.3967 · 2017 · External reference
Integrated patient-derived models delineate individualized therapeutic vulnerabilities of pancreatic cancer
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Xenograft and organoid model systems in cancer research
10.15252/embj.2019101654 · 2019 · External reference
10.1038/nrc.2016.140
10.1038/nrc.2016.140 · External reference
Organoid models of cancer explode with possibilities
10.1016/j.stem.2018.02.010 · 2018 · External reference
10.1038/nature11547
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10.1038/nature14169
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Pancreatic cancer cell lines as patient-derived avatars: genetic characterisation and functional utility
2017 · External reference
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10.1158/2159-8290.cd-18-0349
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10.1038/nature16965
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10.1038/nrg1767 · External reference
Clinically relevant genetic variations in drug metabolizing enzymes
10.2174/138920011795495321 · 2011 · External reference
Copy number variations' effect on drug response still overlooked
10.1038/nm0315-206 · 2015 · External reference
Organoid models of human and mouse ductal pancreatic cancer
10.1016/j.cell.2014.12.021 · 2015 · External reference
10.1242/dev.096628
10.1242/dev.096628 · External reference
10.1038/nm.3973
10.1038/nm.3973 · External reference
Preclinical models of pancreatic ductal adenocarcinoma
10.21037/cco.2017.06.15 · 2017 · External reference
Human pancreatic tumor organoids reveal loss of stem cell niche factor dependence during disease progression
10.1016/j.stem.2017.12.009 · 2018 · External reference
10.1016/j.gde.2019.02.003
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10.1038/s41422-019-0195-y
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New opportunities from the cancer metabolome
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Recent advances in cancer metabolism: a technological perspective
2018 · External reference
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10.1016/j.bbcan.2018.04.009 · External reference
Microenvironmental regulation of cancer cell metabolism: implications for experimental design and translational studies
10.1242/dmm.035758 · 2018 · External reference
Subtype-specific response to bevacizumab is reflected in the metabolome and transcriptome of breast cancer xenografts
10.1016/j.molonc.2012.10.005 · 2013 · External reference
10.1016/j.celrep.2017.11.003
10.1016/j.celrep.2017.11.003 · External reference
Exercise inhibits tumor growth and central carbon metabolism in patient-derived xenograft models of colorectal cancer
10.1186/s40170-018-0190-7 · 2018 · External reference
10.1186/s12943-015-0481-3
10.1186/s12943-015-0481-3 · External reference
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10.1038/483531a · External reference
High drug attrition rates–where are we going wrong?
10.1038/nrclinonc.2011.34 · 2011 · External reference
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