Research graph
References from High-throughput analysis and functional interpretation of extracellular vesicle content in hematological malignancies. Local targets link to admitted publications; unresolved targets remain external evidence.
MicroRNA theragnostics for the clinical management of multiple myeloma
10.1038/leu.2013.262 · 2014 · External reference
Multiple myeloma dell-derived microvesicles are enriched in CD147 expression and enhance tumor cell proliferation
10.18632/oncotarget.2159 · 2014 · External reference
Micro-RNA profiling of exosomes from marrow-derived mesenchymal stromal cells in patients with acute myeloid leukemia: implications in leukemogenesis
10.1007/s12015-017-9762-0 · 2017 · External reference
Exosomes in the serum of Acute Myeloid Leukemia patients induce dendritic cell tolerance: Implications for immunotherapy
10.1016/j.vaccine.2019.01.079 · 2019 · External reference
Transfer of multidrug resistance among acute myeloid leukemia cells via extracellular vesicles and their microRNA cargo
10.1016/j.leukres.2017.09.014 · 2017 · External reference
The secretome of mesenchymal stromal cells: role of extracellular vesicles in immunomodulation
10.1016/j.imlet.2015.06.007 · 2015 · External reference
Extracellular vesicles in hematological malignancies: from biology to therapy
10.3390/ijms18061183 · 2017 · External reference
High serum levels of extracellular vesicles expressing malignancy-related markers are released in patients with various types of hematological neoplastic disorders
10.1007/s13277-015-3741-3 · 2015 · External reference
10.1172/jci66553
10.1172/jci66553 · External reference
10.1126/science.1164390
10.1126/science.1164390 · External reference
Docetaxel-resistance in prostate cancer: evaluating associated phenotypic changes and potential for resistance transfer via exosomes
10.1371/journal.pone.0050999 · 2012 · External reference
10.1101/gr.132159.111
10.1101/gr.132159.111 · External reference
MicroRNAs-based nano-strategies as new therapeutic approach in multiple myeloma to overcome disease progression and drug resistance
10.3390/ijms21093084 · 2020 · External reference
In vivo activity of miR-34a mimics delivered by stable nucleic acid lipid particles (SNALPs) against multiple myeloma
10.1371/journal.pone.0090005 · 2014 · External reference
CLL exosomes modulate the transcriptome and behaviour of recipient stromal cells and are selectively enriched in miR-202-3p
10.1371/journal.pone.0141429 · 2015 · External reference
10.1016/j.biotechadv.2017.12.010
10.1016/j.biotechadv.2017.12.010 · External reference
10.1016/j.ceb.2004.06.003
10.1016/j.ceb.2004.06.003 · External reference
10.1182/blood-2009-09-242719
10.1182/blood-2009-09-242719 · External reference
Circulating exosomal microRNAs in acquired aplastic anemia and myelodysplastic syndromes
10.3324/haematol.2017.182824 · 2018 · External reference
10.1016/j.trecan.2017.10.003
10.1016/j.trecan.2017.10.003 · External reference
A 13 mer LNA-i-miR-221 inhibitor restores drug sensitivity in melphalan-refractory multiple myeloma cells
10.1158/1078-0432.ccr-15-0489 · 2016 · External reference
Exosomes: new players in cancer (Review)
10.3892/or.2017.5714 · 2017 · External reference
Proteomic characterization of circulating extracellular vesicles identifies novel serum myeloma associated markers
10.1016/j.jprot.2015.12.016 · 2016 · External reference
Characterization of multiple myeloma vesicles by label-free relative quantitation
10.1002/pmic.201300142 · 2013 · External reference
Pathway analysis software: annotation errors and solutions
10.1016/j.ymgme.2010.06.005 · 2010 · External reference
10.1007/s00018-017-2595-9
10.1007/s00018-017-2595-9 · External reference
Isolation and characterization of CD34+ blast-derived exosomes in acute myeloid leukemia
2014 · External reference
Circulating exosomes carrying an immunosuppressive cargo interfere with cellular immunotherapy in acute myeloid leukemia
10.1038/s41598-017-14661-w · 2017 · External reference
10.1038/srep11295
10.1038/srep11295 · External reference
Circulating small noncoding RNAs have specific expression patterns in plasma and extracellular vesicles in myelodysplastic syndromes and are predictive of patient outcome
10.3390/cells9040794 · 2020 · External reference
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
10.1038/nprot.2008.211 · 2009 · External reference
10.1038/leu.2014.279
10.1038/leu.2014.279 · External reference
Exosomes and their role in the micro-/macro-environment: a comprehensive review
10.7555/jbr.30.20150162 · 2017 · External reference
Elevated serum exosomal miR-125b level as a potential marker for poor prognosis in intermediate-risk acute myeloid leukemia
10.1159/000491584 · 2018 · External reference
Expression of miR-652-3p and effect on apoptosis and drug sensitivity in pediatric acute lymphoblastic leukemia
10.1155/2018/5724686 · 2018 · External reference
The diagnostic and prognostic value of plasma microRNA-125b-5p in patients with multiple myeloma
2018 · External reference
Global miRNA expression analysis identifies novel key regulators of plasma cell differentiation and malignant plasma cell
10.1093/nar/gkx327 · 2017 · External reference
10.1200/jco.2010.31.0904
10.1200/jco.2010.31.0904 · External reference
10.1038/leu.2017.259
10.1038/leu.2017.259 · External reference
10.1101/gad.1767609
10.1101/gad.1767609 · External reference
Exosomes as a multicomponent biomarker platform in cancer
2020 · External reference
Targeting miR-21 inhibits in vitro and in vivo multiple myeloma cell growth
10.1158/1078-0432.ccr-12-3325 · 2013 · External reference
10.1016/j.tcb.2016.11.003
10.1016/j.tcb.2016.11.003 · External reference
Prognostic role of circulating exosomal miRNAs in multiple myeloma
10.1182/blood-2016-09-742296 · 2017 · External reference
Clinical role of microRNAs in cytogenetically normal acute myeloid leukemia: miR-155 upregulation independently identifies high-risk patients
10.1200/jco.2012.45.6228 · 2013 · External reference
10.1038/sj.leu.2404245
10.1038/sj.leu.2404245 · External reference
10.1093/nar/gkr828
10.1093/nar/gkr828 · External reference
10.1016/j.jprot.2010.06.006
10.1016/j.jprot.2010.06.006 · External reference
10.1002/pmic.200900351
10.1002/pmic.200900351 · External reference
Oncosomes – large and small: what are they, where they came from?
10.3402/jev.v5.33109 · 2016 · External reference
Expression profiling of circulating microvesicles reveals intercellular transmission of oncogenic pathways
10.1158/1541-7786.mcr-16-0307 · 2017 · External reference
Long non-coding RNAs: new players in hematopoiesis and leukemia
2015 · External reference
Sense and nonsense of pathway analysis software in proteomics
10.1021/pr200654k · 2011 · External reference
Attenuation of dexamethasone-induced cell death in multiple myeloma is mediated by miR-125b expression
10.4161/cc.25251 · 2013 · External reference
10.1182/blood-2014-12-618025
10.1182/blood-2014-12-618025 · External reference
10.1016/j.leukres.2017.11.011
10.1016/j.leukres.2017.11.011 · External reference
10.1038/nm.2753
10.1038/nm.2753 · External reference
Emerging role of miR-106b-25/miR-17-92 clusters in the control of transforming growth factor β signaling
10.1158/0008-5472.can-08-1768 · 2008 · External reference
S100–A9 protein in exosomes from chronic lymphocytic leukemia cells promotes NF-κB activity during disease progression
10.1182/blood-2017-02-769851 · 2017 · External reference
Metabolomic profiling of extracellular vesicles and alternative normalization methods reveal enriched metabolites and strategies to study prostate cancer-related changes
10.7150/thno.19890 · 2017 · External reference
miR-155 expression and correlation with clinical outcome in pediatric AML: a report from Children’s Oncology Group
10.1002/pbc.26157 · 2016 · External reference
Extracellular vesicles released from chronic lymphocytic leukemia cells exhibit a disease relevant mRNA signature and transfer mRNA to bystander cells
10.3324/haematol.2016.153197 · 2017 · External reference
10.1172/jci81131
10.1172/jci81131 · External reference
10.1038/nri3622
10.1038/nri3622 · External reference
BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression
10.1172/jci66517 · 2013 · External reference
Exosomes and other extracellular vesicles-mediated microRNA delivery for cancer therapy
10.21037/tcr.2017.09.29 · 2017 · External reference
Extracellular vesicles in DLBCL provide abundant clues to aberrant transcriptional programming and genomic alterations
10.1182/blood-2017-12-821843 · 2018 · External reference
10.1038/nmeth.2212
10.1038/nmeth.2212 · External reference
Clinical advances in molecular biomarkers for cancer diagnosis and therapy
10.3390/ijms140714771 · 2013 · External reference
10.1038/ncb1800
10.1038/ncb1800 · External reference
10.1182/blood-2006-05-024844
10.1182/blood-2006-05-024844 · External reference
Taking metabolism on the road
10.1038/nchembio.2455 · 2017 · External reference
10.1038/cmi.2014.42
10.1038/cmi.2014.42 · External reference
10.1038/onc.2012.295
10.1038/onc.2012.295 · External reference
10.1038/ncb1596
10.1038/ncb1596 · External reference
Tumorigenicity of the miR-17-92 cluster distilled
10.1101/gad.1887110 · 2010 · External reference
Minimal residual disease in acute myeloid leukemia is predicted by an apoptosis-resistant protein profile at diagnosis
10.1158/1078-0432.ccr-04-1973 · 2005 · External reference
A flow cytometric method to detect apoptosis-related protein expression in minimal residual disease in acute myeloid leukemia
10.1038/sj.leu.2402885 · 2003 · External reference
Alterations in acute myeloid leukaemia bone marrow stromal cell exosome content coincide with gains in tyrosine kinase inhibitor resistance
10.1111/bjh.13551 · 2016 · External reference
Myeloma cell adhesion to bone marrow stromal cells confers drug resistance by microRNA-21 up-regulation
10.3109/10428194.2011.591004 · 2011 · External reference
Stromal cells and CD40 ligand (CD154) alter the miRNome and induce miRNA clusters including, miR-125b/miR-99a/let-7c and miR-17-92 in chronic lymphocytic leukaemia
10.1038/leu.2011.299 · 2012 · External reference
Exosomes secreted by apoptosis-resistant acute myeloid leukemia (AML) blasts harbor regulatory network proteins potentially involved in antagonism of apoptosis
10.1074/mcp.m115.052944 · 2016 · External reference
MiR-125b expression affects the proliferation and apoptosis of human glioma cells by targeting Bmf
10.1159/000218181 · 2009 · External reference
10.3402/jev.v4.27066
10.3402/jev.v4.27066 · External reference
Focus on exosomes: novel pathogenic components of leukemia
2019 · External reference
Long noncoding RNAs: a potential novel class of cancer biomarkers
10.3389/fgene.2015.00145 · 2015 · External reference
10.1182/blood-2014-12-618470
10.1182/blood-2014-12-618470 · External reference
10.1093/biosci/biv084
10.1093/biosci/biv084 · External reference
Evidence of novel miR-34a-based therapeutic approaches for multiple myeloma treatment
10.1038/s41598-017-18186-0 · 2017 · External reference
Potential role of exosome-associated microRNA panels and in vivo environment to predict drug resistance for patients with multiple myeloma
10.18632/oncotarget.9021 · 2016 · External reference
10.1158/0008-5472.can-15-0457
10.1158/0008-5472.can-15-0457 · External reference