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References from Structural insight into the recognition of S -adenosyl-L-homocysteine and sinefungin in SARS-CoV-2 Nsp16/Nsp10 RNA cap 2′-O-Methyltransferase. Local targets link to admitted publications; unresolved targets remain external evidence.
COVID-19: fighting panic with information
10.1016/s0140-6736(20)30379-2 · 2020 · External reference
novel coronavirus outbreak in Wuhan, China
2019 · External reference
10.1002/jmv.25678
10.1002/jmv.25678 · External reference
10.1016/j.chom.2020.02.001
10.1016/j.chom.2020.02.001 · External reference
10.1126/science.abb4489
10.1126/science.abb4489 · External reference
10.1016/j.ijantimicag.2020.106054
10.1016/j.ijantimicag.2020.106054 · External reference
The architecture of SARS-CoV-2 transcriptome
2020 · External reference
10.1016/j.cell.2020.04.004
10.1016/j.cell.2020.04.004 · External reference
COVID-19 infection: Origin, transmission, and characteristics of human coronaviruses
10.1016/j.jare.2020.03.005 · 2020 · External reference
Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods
2020 · External reference
10.1146/annurev-virology-100114-055218
10.1146/annurev-virology-100114-055218 · External reference
10.1101/2020.04.17.047498
10.1101/2020.04.17.047498 · External reference
Binding of the methyl donor S-adenosyl-l-methionine to Middle East respiratory syndrome coronavirus 2'-O-methyltransferase nsp16 promotes recruitment of the allosteric activator nsp10
10.1128/jvi.02217-16 · 2017 · External reference
10.1016/j.antiviral.2014.02.002
10.1016/j.antiviral.2014.02.002 · External reference
10.1371/journal.ppat.1002059
10.1371/journal.ppat.1002059 · External reference
In vitro reconstitution of SARS-coronavirus mRNA cap methylation
10.1371/annotation/a0dde376-2eb1-4ce3-8887-d29f5ba6f162 · 2010 · External reference
10.1016/j.cytogfr.2014.05.002
10.1016/j.cytogfr.2014.05.002 · External reference
10.1038/ni.1979
10.1038/ni.1979 · External reference
10.1016/s0022-2836(03)00865-9
10.1016/s0022-2836(03)00865-9 · External reference
The viral RNA capping machinery as a target for antiviral drugs
10.1016/j.antiviral.2012.07.007 · 2012 · External reference
Effects of S-adenosylhomocysteine analogues on vaccinia viral messenger ribonucleic acid synthesis and methylation
10.1021/bi00536a011 · 1982 · External reference
Sinefungin, a potent inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication
10.1016/s0021-9258(17)34682-3 · 1978 · External reference
Unresolved reference
External reference
Unresolved reference
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Structural basis for sequence-nonspecific recognition of 5'-capped mRNA by a cap-modifying enzyme
10.1016/s1097-2765(00)80044-1 · 1998 · External reference
Coronavirus nonstructural protein 16 is a cap-0 binding enzyme possessing (nucleoside-2'O)-methyltransferase activity
10.1128/jvi.00407-08 · 2008 · External reference
10.3390/ecsoc-3-01775
10.3390/ecsoc-3-01775 · External reference
pKa based protonation states and microspecies for protein–ligand docking
10.1007/s10822-010-9385-x · 2010 · External reference
10.1021/ct100578z
10.1021/ct100578z · External reference
Unresolved reference
2009 · External reference
Butoxy mansonone G inhibits STAT3 and Akt signaling pathways in non-small cell lung cancers: Combined experimental and theoretical investigations
10.3390/cancers11040437 · 2019 · External reference
Enhanced solubility and anticancer potential of mansonone G by β-cyclodextrin-based host-guest complexation: A computational and experimental study
10.3390/biom9100545 · 2019 · External reference
Binding hotspot and activation mechanism of maltitol and lactitol toward the human sweet taste receptor
10.1021/acs.jafc.0c02580 · 2020 · External reference
Revised RNA dihedral parameters for the amber force field improve RNA molecular dynamics
10.1021/acs.jctc.6b00870 · 2017 · External reference
10.1002/jcc.20035
10.1002/jcc.20035 · External reference
10.1021/acs.jctc.5b00255
10.1021/acs.jctc.5b00255 · External reference
10.1063/1.445869
10.1063/1.445869 · External reference
10.1063/1.464397
10.1063/1.464397 · External reference
10.1016/0021-9991(77)90098-5
10.1016/0021-9991(77)90098-5 · External reference
10.1021/ct400341p
10.1021/ct400341p · External reference
The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities
10.1517/17460441.2015.1032936 · 2015 · External reference
UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations
10.1111/bph.12669 · 2014 · External reference
10.1021/ar000033j
10.1021/ar000033j · External reference
10.1021/j100058a043
10.1021/j100058a043 · External reference
A water-swap reaction coordinate for the calculation of absolute protein-ligand binding free energies
10.1063/1.3519057 · 2011 · External reference
10.1039/c3fd00125c
10.1039/c3fd00125c · External reference
S-adenosyl-homocysteine is a weakly bound inhibitor for a flaviviral methyltransferase
10.1371/journal.pone.0076900 · 2013 · External reference
10.1371/journal.ppat.1002294
10.1371/journal.ppat.1002294 · External reference
10.1021/acs.jmedchem.9b01238
10.1021/acs.jmedchem.9b01238 · External reference
Sinefungin derivatives as inhibitors and structure probes of protein lysine methyltransferase SETD2
10.1021/ja307060p · 2012 · External reference
Atomistic mechanisms underlying the activation of the G protein-coupled sweet receptor heterodimer by sugar alcohol recognition
10.1038/s41598-019-46668-w · 2019 · External reference
Two zinc-binding domains in the transporter AdcA from Streptococcus pyogenes facilitate high-affinity binding and fast transport of zinc
10.1074/jbc.m117.818997 · 2018 · External reference
Rosmarinic acid as a potent influenza neuraminidase inhibitor. In vitro and in silico study
10.2174/1568026619666191118110155 · 2020 · External reference