Research graph
References from In silico and in vitro studies reveal complement system drives coagulation cascade in SARS-CoV-2 pathogenesis. Local targets link to admitted publications; unresolved targets remain external evidence.
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Cucurbitacin E inhibits TNF-α-induced inflammatory cytokine production in human synoviocyte MH7A cells via suppression of PI3K/Akt/NF-κB pathways
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Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases
2020 · External reference
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Incidence of asymptomatic deep vein thrombosis in patients with COVID-19 pneumonia and elevated D-dimer levels
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The human platelet as an innate immune cell: interactions between activated platelets and the complement system
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Functional tissue factor is entirely cell surface expressed on lipopolysaccharide-stimulated human blood monocytes and a constitutively tissue factor-producing neoplastic cell line
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C5 chemotactic fragment induces leukocyte production of tissue factor activity: a link between complement and coagulation
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Activation of C-type lectin receptor and (RIG)-I-like receptors contributes to proinflammatory response in middle east respiratory syndrome coronavirus-infected macrophages
2020 · External reference
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2020 · External reference
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Coagulation, inflammation, and apoptosis: different roles for protein S and the protein S-C4b binding protein complex
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2020 · External reference
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Unresolved reference
External reference
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