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References from Transcriptomic signatures and repurposing drugs for COVID-19 patients: findings of bioinformatics analyses. Local targets link to admitted publications; unresolved targets remain external evidence.
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10.3389/fimmu.2020.00827
10.3389/fimmu.2020.00827 · External reference
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
2020 · External reference
Compassionate Use of Remdesivir for Patients with Severe Covid-19
2020 · External reference
10.1016/s0140-6736(20)31022-9
10.1016/s0140-6736(20)31022-9 · External reference
10.1093/nar/gkaa019
10.1093/nar/gkaa019 · External reference
10.1093/nargab/lqaa084
10.1093/nargab/lqaa084 · External reference
10.1093/nar/gkv1308
10.1093/nar/gkv1308 · External reference
10.1093/bioinformatics/btaa224
10.1093/bioinformatics/btaa224 · External reference
10.1126/science.abb8925
10.1126/science.abb8925 · External reference
Cytokine Release Syndrome in COVID-19 Patients, A New Scenario for an Old Concern: The Fragile Balance between Infections and Autoimmunity
10.3390/ijms21093330 · 2020 · External reference
10.1038/s41587-020-0528-x
10.1038/s41587-020-0528-x · External reference
EpiDenovo: a platform for linking regulatory de novo mutations to developmental epigenetics and diseases
10.1093/nar/gkx918 · 2018 · External reference
10.1038/s41587-019-0201-4
10.1038/s41587-019-0201-4 · External reference
10.1093/bioinformatics/btp352
10.1093/bioinformatics/btp352 · External reference
10.1186/s13059-014-0550-8
10.1186/s13059-014-0550-8 · External reference
OncoVar: an integrated database and analysis platform for oncogenic driver variants in cancers
2020 · External reference
10.1038/s41467-019-09234-6
10.1038/s41467-019-09234-6 · External reference
10.1093/nar/gky900
10.1093/nar/gky900 · External reference
10.1093/nar/gky1139
10.1093/nar/gky1139 · External reference
10.1016/j.ccell.2018.08.018
10.1016/j.ccell.2018.08.018 · External reference
10.1093/nar/gkz401
10.1093/nar/gkz401 · External reference
Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd
2016 · External reference
10.1016/j.cell.2020.04.026
10.1016/j.cell.2020.04.026 · External reference
Role of immunosuppressive therapy in rheumatic diseases concurrent with COVID-19
10.1136/annrheumdis-2020-217460 · 2020 · External reference
10.1016/s0140-6736(20)30628-0
10.1016/s0140-6736(20)30628-0 · External reference
10.1080/22221751.2020.1747363
10.1080/22221751.2020.1747363 · External reference
10.1016/j.cell.2015.04.001
10.1016/j.cell.2015.04.001 · External reference
10.1038/s41380-018-0304-1
10.1038/s41380-018-0304-1 · External reference
Prognostic Genes of Breast Cancer Identified by Gene Co-expression Network Analysis
10.3389/fonc.2018.00374 · 2018 · External reference
A Dynamic Immune Response Shapes COVID-19 Progression
2020 · External reference
10.1074/jbc.m110.171256
10.1074/jbc.m110.171256 · External reference
Human polymorphonuclear leukocytes adhere to complement factor H through an interaction that involves alphaMbeta2 (CD11b/CD18)
10.4049/jimmunol.160.8.4057 · 1998 · External reference
Factor H and factor H-related protein 1 bind to human neutrophils via complement receptor 3, mediate attachment to Candida albicans, and enhance neutrophil antimicrobial activity
10.4049/jimmunol.0901702 · 2010 · External reference
10.1084/jem.20091021
10.1084/jem.20091021 · External reference
10.1074/jbc.m208602200
10.1074/jbc.m208602200 · External reference
CD22: a regulator of innate and adaptive B cell responses and autoimmunity
10.3389/fimmu.2018.02235 · 2018 · External reference
10.1016/j.bbi.2016.02.001
10.1016/j.bbi.2016.02.001 · External reference
Modulation of TLR3/TLR4 inflammatory signaling by the GABAB receptor agonist baclofen in glia and immune cells: relevance to therapeutic effects in multiple sclerosis
10.3389/fncel.2015.00284 · 2015 · External reference
Rituximab for granulomatosis with polyangiitis in the pandemic of covid-19: lessons from a case with severe pneumonia
2020 · External reference
Triple combination of interferon beta-1b, lopinavir–ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial
2020 · External reference
Coronavirus disease 2019 and transplantation: The combination of lopinavir/ritonavir and hydroxychloroquine is responsible for excessive tacrolimus trough level and unfavorable outcome
2020 · External reference
10.1056/nejmoa2001282
10.1056/nejmoa2001282 · External reference
10.7326/m20-1334
10.7326/m20-1334 · External reference
10.1136/bmj.m1432
10.1136/bmj.m1432 · External reference
COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options
2020 · External reference
Outcomes of hydroxychloroquine usage in United States veterans hospitalized with Covid-19
2020 · External reference
10.1016/j.cytogfr.2020.06.001
10.1016/j.cytogfr.2020.06.001 · External reference
A cytokine super cyclone in COVID-19 patients with risk factors: the therapeutic potential of BCG immunization
10.1016/j.cytogfr.2020.06.014 · 2020 · External reference
Functional exhaustion of antiviral lymphocytes in COVID-19 patients
2020 · External reference
Pathological evidence for residual SARS-CoV-2 in pulmonary tissues of a ready-for-discharge patient
2020 · External reference
COVID-19: risk for cytokine targeting in chronic inflammatory diseases?
10.1038/s41577-020-0312-7 · 2020 · External reference
Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19
10.1056/nejmoa2015432 · 2020 · External reference
Nervous system involvement after infection with COVID-19 and other coronaviruses
2020 · External reference
10.1001/jamaneurol.2020.1127
10.1001/jamaneurol.2020.1127 · External reference
Does COVID-19 affect male fertility?
2020 · External reference
Effect of SARS-CoV-2 infection upon male gonadal function: A single center-based study
2020 · External reference
10.3389/fimmu.2020.00827
10.3389/fimmu.2020.00827 · External reference
10.1016/j.chom.2016.01.007
10.1016/j.chom.2016.01.007 · External reference
Trials of anti-tumour necrosis factor therapy for COVID-19 are urgently needed
10.1016/s0140-6736(20)30858-8 · 2020 · External reference
Recovery from COVID-19 in a patient with spondyloarthritis treated with TNF-alpha inhibitor etanercept
2020 · External reference
Effective treatment of severe COVID-19 patients with tocilizumab
2020 · External reference
Cytokine Release Syndrome in COVID-19 Patients, A New Scenario for an Old Concern: The Fragile Balance between Infections and Autoimmunity
10.3390/ijms21093330 · 2020 · External reference
Unresolved reference
External reference
10.1056/nejmoa2001282
10.1056/nejmoa2001282 · External reference
Host targeted activity of pyrazinamide in Mycobacterium tuberculosis infection
10.1371/journal.pone.0074082 · 2013 · External reference
Immune modulatory effects of statins
10.1111/imm.12902 · 2018 · External reference
10.1155/2014/872370
10.1155/2014/872370 · External reference
10.1128/mbio.01120-15
10.1128/mbio.01120-15 · External reference
Statins in coronavirus outbreak: It's time for experimental and clinical studies
10.1016/j.phrs.2020.104803 · 2020 · External reference
Statins and the COVID-19 main protease: in silico evidence on direct interaction
10.5114/aoms.2020.94655 · 2020 · External reference
Unresolved reference
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Role of immunosuppressive therapy in rheumatic diseases concurrent with covid-19
2020 · External reference
Early Short Course Corticosteroids in Hospitalized Patients with COVID-19
2020 · External reference
Use of glucocorticoids in patients with adrenal insufficiency and COVID-19 infection
10.1016/s2213-8587(20)30149-2 · 2020 · External reference
Separation of chlorogenic acid from honeysuckle crude extracts by macroporous resins
10.1016/j.jchromb.2008.04.016 · 2008 · External reference
Bao L-d. Exploring the Active Compounds of Traditional Mongolian Medicine in Intervention of Novel Coronavirus (COVID-19) Based on Molecular Docking Method
2020 · External reference
10.1016/j.ijantimicag.2020.105971
10.1016/j.ijantimicag.2020.105971 · External reference
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Curcumin modulates the inflammatory response and inhibits subsequent fibrosis in a mouse model of viral-induced acute respiratory distress syndrome
10.1371/journal.pone.0057285 · 2013 · External reference
Virtual screening of immunomodulatory medicinal compounds as promising anti-SARS-COV-2 inhibitors
10.2217/fvl-2020-0079 · 2020 · External reference
Anti-inflammatory effects of resveratrol: Mechanistic insights
10.3390/ijms19061812 · 2018 · External reference
Genistein as an anti-inflammatory agent
10.1007/s00011-003-1182-8 · 2003 · External reference
10.1016/j.immuni.2016.04.013
10.1016/j.immuni.2016.04.013 · External reference
10.1016/j.autrev.2014.11.008
10.1016/j.autrev.2014.11.008 · External reference
10.1042/bst20180169
10.1042/bst20180169 · External reference
Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections
10.3390/nu12041181 · 2020 · External reference