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References from Computational design of SARS-CoV-2 spike glycoproteins to increase immunogenicity by T cell epitope engineering. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
External reference
10.1056/nejmoa2034577
10.1056/nejmoa2034577 · External reference
10.1056/nejmoa2028436
10.1056/nejmoa2028436 · External reference
10.1101/2020.07.28.225649
10.1101/2020.07.28.225649 · External reference
10.1016/s0140-6736(20)31604-4
10.1016/s0140-6736(20)31604-4 · External reference
10.1016/s0140-6736(20)31208-3
10.1016/s0140-6736(20)31208-3 · External reference
10.1016/j.cell.2020.05.015
10.1016/j.cell.2020.05.015 · External reference
10.1016/s0140-6736(20)30251-8
10.1016/s0140-6736(20)30251-8 · External reference
10.3201/eid1103.040906
10.3201/eid1103.040906 · External reference
10.1128/cmr.00102-14
10.1128/cmr.00102-14 · External reference
Intranasal immunization with plasmid DNA encoding spike protein of SARS-coronavirus/polyethylenimine nanoparticles elicits antigen-specific humoral and cellular immune responses
10.1186/1471-2172-11-65 · 2010 · External reference
10.1038/nature02463
10.1038/nature02463 · External reference
10.1038/s41586-020-2012-7
10.1038/s41586-020-2012-7 · External reference
10.1038/s41577-020-0311-8
10.1038/s41577-020-0311-8 · External reference
COVID-19 coronavirus vaccine design using reverse vaccinology and machine learning
10.3389/fimmu.2020.01581 · 2020 · External reference
A sequence homology and bioinformatic approach can predict candidate targets for immune responses to SARS-CoV-2
10.1016/j.chom.2020.03.002 · 2020 · External reference
Reverse vaccinology approach to design a novel multi-epitope vaccine candidate against COVID-19: an in silico study
2020 · External reference
Neutralizing antibody responses to SARS-CoV-2 in a COVID-19 recovered patient cohort and their implications
2020 · External reference
10.1016/j.immuni.2020.04.023
10.1016/j.immuni.2020.04.023 · External reference
10.1016/j.cell.2020.05.025
10.1016/j.cell.2020.05.025 · External reference
10.1126/science.abb2507
10.1126/science.abb2507 · External reference
10.1016/j.cell.2020.06.025
10.1016/j.cell.2020.06.025 · External reference
10.1016/j.cell.2020.04.031
10.1016/j.cell.2020.04.031 · External reference
10.1038/s41586-020-2550-z
10.1038/s41586-020-2550-z · External reference
10.1038/s41586-020-2598-9
10.1038/s41586-020-2598-9 · External reference
10.1016/j.micpath.2020.104236
10.1016/j.micpath.2020.104236 · External reference
10.1126/science.1243283
10.1126/science.1243283 · External reference
10.1038/s41594-020-0479-4
10.1038/s41594-020-0479-4 · External reference
Experimental evolution of a new enzymatic function. II. Evolution of multiple functions for EBG enzyme in E. coli
1978 · External reference
Protein-RNA interactions: Exploring binding patterns with a three-dimensional superposition analysis of high resolution structures
10.1093/bioinformatics/btl470 · 2006 · External reference
10.1101/2020.05.19.104042
10.1101/2020.05.19.104042 · External reference
10.1016/j.jmb.2019.02.028
10.1016/j.jmb.2019.02.028 · External reference
10.1021/acs.jproteome.0c00129
10.1021/acs.jproteome.0c00129 · External reference
10.1093/nar/gki524
10.1093/nar/gki524 · External reference
10.1093/bioinformatics/btz740
10.1093/bioinformatics/btz740 · External reference
Computational design of enzyme–ligand binding using a combined energy function and deterministic sequence optimization algorithm
10.1007/s00894-015-2742-x · 2015 · External reference
10.1016/j.cell.2020.06.043
10.1016/j.cell.2020.06.043 · External reference
10.1002/gch2.1018
10.1002/gch2.1018 · External reference
Intrinsic protein disorder annotation in 2020
2020 · External reference
10.1093/bioinformatics/btm270
10.1093/bioinformatics/btm270 · External reference
10.18632/aging.103416
10.18632/aging.103416 · External reference
10.1021/acs.jproteome.0c00717
10.1021/acs.jproteome.0c00717 · External reference
10.1016/b978-0-12-381270-4.00019-6
10.1016/b978-0-12-381270-4.00019-6 · External reference
10.1111/imm.12889
10.1111/imm.12889 · External reference
10.1093/nar/gkz452
10.1093/nar/gkz452 · External reference
The immune epitope database and analysis resource in epitope discovery and synthetic vaccine design
10.3389/fimmu.2017.00278 · 2017 · External reference
10.1016/j.jim.2015.03.022
10.1016/j.jim.2015.03.022 · External reference
The universal protein resource (UniProt)
2008 · External reference
10.1371/journal.pone.0001831
10.1371/journal.pone.0001831 · External reference
10.1073/pnas.89.22.10915
10.1073/pnas.89.22.10915 · External reference
Sea view version 4: a multiplatform graphical user interface for sequence alignment and phylogenetic tree building
10.1093/molbev/msp259 · 2010 · External reference
10.1002/prot.20264
10.1002/prot.20264 · External reference
10.1002/prot.25798
10.1002/prot.25798 · External reference
10.1093/bioinformatics/btz291
10.1093/bioinformatics/btz291 · External reference
10.1038/s41401-020-0485-4
10.1038/s41401-020-0485-4 · External reference
Unresolved reference
External reference
10.1101/gr.849004
10.1101/gr.849004 · External reference
10.1016/j.softx.2015.06.001 · Admitted local publication
10.1021/ct300400x
10.1021/ct300400x · External reference
10.1063/1.445869
10.1063/1.445869 · External reference
Evaluation of active designs of cephalosporin C acylase by molecular dynamics simulation and molecular docking
10.1007/s00894-014-2314-5 · 2014 · External reference
10.1039/c9ra02406a
10.1039/c9ra02406a · External reference
10.1002/(sici)1096-987x(199709)18:12<1463::aid-jcc4>3.0.co;2-h
10.1002/(sici)1096-987x(199709)18:12<1463::aid-jcc4>3.0.co;2-h · External reference
10.1063/1.470117
10.1063/1.470117 · External reference
10.1063/1.2408420
10.1063/1.2408420 · External reference
10.1063/1.328693
10.1063/1.328693 · External reference
Can SARS-CoV-2 accumulate mutations in the S-protein to increase pathogenicity?
10.1021/acsptsci.0c00113 · 2020 · External reference
A humanized mouse model identifies key amino acids for low immunogenicity of H7N9 vaccines
10.1038/s41598-017-01372-5 · 2017 · External reference
10.1016/j.vaccine.2019.06.044
10.1016/j.vaccine.2019.06.044 · External reference
Removing T-cell epitopes with computational protein design
10.1073/pnas.1321126111 · 2014 · External reference
10.1371/journal.pone.0020161
10.1371/journal.pone.0020161 · External reference
10.1038/mtm.2015.21
10.1038/mtm.2015.21 · External reference
10.1007/978-1-4939-6637-0_20
10.1007/978-1-4939-6637-0_20 · 2017 · External reference
Serological responses to an avian influenza A/H7N9 vaccine mixed at the point-of-use with MF59 adjuvant a randomized clinical trial
10.1001/jama.2014.12854 · 2014 · External reference
10.3201/eid2002.131094
10.3201/eid2002.131094 · External reference
10.1016/s1473-3099(15)00378-3
10.1016/s1473-3099(15)00378-3 · External reference
10.1371/journal.pcbi.1002412
10.1371/journal.pcbi.1002412 · External reference
The two-faced T cell epitope: examining the host-microbe interface with JanusMatrix
10.4161/hv.24615 · 2013 · External reference
Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses
2020 · External reference
