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References from Toxoplasma and Eimeria co-opt the host cFos expression for intracellular development in mammalian cells. Local targets link to admitted publications; unresolved targets remain external evidence.
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Taming parasites by tailoring them
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The Toxoplasma effector TEEGR promotes parasite persistence by modulating NF-kappaB signalling via EZH2
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Toxoplasma gondii TgIST co-opts host chromatin repressors dampening STAT1-dependent gene regulation and IFN-gamma-mediated host defenses
10.1084/jem.20160340 · 2016 · External reference
Characterization of a Toxoplasma effector uncovers an alternative GSK3/beta-catenin-regulatory pathway of inflammation
2018 · External reference
Unresolved reference
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10.1038/mi.2013.115
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Dual RNA-seq reveals no plastic transcriptional response of the coccidian parasite Eimeria falciformis to host immune defenses
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Influence of Eimeria falciformis infection on gut microbiota and metabolic pathways in mice
10.1128/iai.00073-18 · 2018 · External reference
Detection and quantification of house mouse Eimeria at the species level – challenges and solutions for the assessment of coccidia in wildlife
2019 · External reference
The genome of Eimeria falciformis–reduction and specialization in a single host apicomplexan parasite
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Generalist Eimeria species in rodents: multilocus analyses indicate inadequate resolution of established markers
10.1002/ece3.5992 · 2020 · External reference
Lipid analysis of Eimeria sporozoites reveals exclusive phospholipids, a phylogenetic mosaic of endogenous synthesis, and a host-independent lifestyle
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CD8+ cells protect mice against reinfection with the intestinal parasite Eimeria falciformis
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The transcription factor Fos: a Janus-type regulator in health and disease
2009 · External reference
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c-Fos as a transcription factor: a stressful (re)view from a functional map
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Inducible binding of a factor to the c-fos regulatory region
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Activation of the c-fos gene by UV and phorbol ester: different signal transduction pathways converge to the same enhancer element
1988 · External reference
Temporary disruption of the plasma membrane is required for c-fos expression in response to mechanical stress
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Leishmania-induced inactivation of the macrophage transcription factor AP-1 is mediated by the parasite metalloprotease GP63
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Murine macrophage transcriptional and functional responses to Bacillus anthracis edema toxin
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c-Fos regulates hepatitis C virus propagation
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Berberine modulates AP-1 activity to suppress HPV transcription and downstream signaling to induce growth arrest and apoptosis in cervical cancer cells
10.1186/1476-4598-10-39 · 2011 · External reference
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Toxoplasma gondii dense granule protein GRA24 drives MyD88-independent p38 MAPK activation, IL-12 production and induction of protective immunity
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The secreted acid phosphatase domain-containing GRA44 from Toxoplasma gondii is required for c-Myc induction in infected cells
10.1128/msphere.00877-19 · 2020 · External reference
Toxoplasma GRA15 activates the NF-kappaB pathway through interactions with TNF receptor-associated factors
10.1128/mbio.00808-19 · 2019 · External reference
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Increase in the nuclear localization of PTEN by the Toxoplasma GRA16 protein and subsequent induction of p53‐dependent apoptosis and anticancer effect
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Host cell subversion by toxoplasma GRA16, an exported dense granule protein that targets the host cell nucleus and alters gene expression
10.1016/j.chom.2013.03.002 · 2013 · External reference
Toxoplasma uses GRA16 to upregulate host c-Myc
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Establishment of conditionally immortalized epithelial cell lines from both colon and small intestine of adult H-2Kb-tsA58 transgenic mice:
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Primary mouse fibroblasts deficient for c-Fos, p53 or for both proteins are hypersensitive to UV light and alkylating agent-induced chromosomal breakage and apoptosis
2000 · External reference
Mouse strain variation and effects of oocyst dose in infection of mice with Eimeria falciformis, a coccidian parasite of the large intestine
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