Research graph
References from COVID-19 pandemic: Can zinc supplementation provide an additional shield against the infection?. Local targets link to admitted publications; unresolved targets remain external evidence.
Trace mineral micronutrients and chronic periodontitis-a review
10.1007/s12011-016-0832-y · 2017 · External reference
10.1152/physrev.00035.2014
10.1152/physrev.00035.2014 · External reference
Zinc: the metal of life
10.1111/1541-4337.12067 · 2014 · External reference
Zinc adequacy is essential for the maintenance of optimal oral health
10.3390/nu12040949 · 2020 · External reference
10.1016/j.ijid.2020.09.008
10.1016/j.ijid.2020.09.008 · External reference
Associations of essential and toxic metals/metalloids in whole blood with both disease severity and mortality in patients with COVID-19
10.1096/fj.202002346rr · 2021 · External reference
10.3390/ijerph7041342
10.3390/ijerph7041342 · External reference
Dietary factors influencing zinc absorption
10.1093/jn/130.5.1378s · 2000 · External reference
Three cases of COVID-19 disease with colonic manifestations
10.14309/ajg.0000000000000692 · 2020 · External reference
COVID-19 outpatients: early risk-stratified treatment with zinc plus low-dose hydroxychloroquine and azithromycin: a retrospective case series study
10.1016/j.ijantimicag.2020.106214 · 2020 · External reference
Characterization of critically Ill COVID-19 patients at a brooklyn safety-net hospital
2020 · External reference
Clinical outcomes of early treatment with doxycycline for 89 high-risk COVID-19 patients in long-term care facilities in New York
2020 · External reference
Zinc ion availability–the determinant of efficacy in zinc lozenge treatment of common colds
10.1093/oxfordjournals.jac.a020864 · 1997 · External reference
Common cold treatment using zinc
10.1001/jama.2015.8174 · 2015 · External reference
10.1093/advances/nmz013
10.1093/advances/nmz013 · External reference
10.1016/j.mehy.2009.10.017
10.1016/j.mehy.2009.10.017 · External reference
Effect of antioxidants on apoptosis induced by influenza virus infection: inhibition of viral gene replication and transcription with pyrrolidine dithiocarbamate
10.1016/s0166-3542(02)00109-2 · 2002 · External reference
Inhibition of H1N1 influenza virus infection by zinc oxide nanoparticles: another emerging application of nanomedicine
10.1186/s12929-019-0563-4 · 2019 · External reference
Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture
10.1371/journal.ppat.1001176 · 2010 · External reference
Zinc and SARS-CoV-2: a molecular modeling study of Zn interactions with RNA-dependent RNA-polymerase and 3C-like proteinase enzymes
10.3892/ijmm.2020.4790 · 2021 · External reference
Low zinc levels at clinical admission associates with poor outcomes in COVID-19
2020 · External reference
Effect of zinc salts on respiratory syncytial virus replication
10.1128/aac.48.3.783-790.2004 · 2004 · External reference
Prevention of diarrhea and pneumonia by zinc supplementation in children in developing countries: pooled analysis of randomized controlled trials. Zinc Investigators' Collaborative Group
10.1016/s0022-3476(99)70086-7 · 1999 · External reference
Duration of symptoms and plasma cytokine levels in patients with the common cold treated with zinc acetate. A randomized, double-blind, placebo-controlled trial
10.7326/0003-4819-133-4-200008150-00006 · 2000 · External reference
10.1128/jvi.73.2.1649-1654.1999
10.1128/jvi.73.2.1649-1654.1999 · External reference
Zinc supplementation therapy improves the outcome of patients with chronic hepatitis C
2012 · External reference
Zinc supplementation improves the outcome of chronic hepatitis C and liver cirrhosis
10.3164/jcbn.jcbn08-246 · 2009 · External reference
Zinc supplementation prevents the increase of transaminase in chronic hepatitis C patients during combination therapy with pegylated interferon alpha-2b and ribavirin
10.3177/jnsv.53.213 · 2007 · External reference
Zinc supplementation reconstitutes the production of interferon-alpha by leukocytes from elderly persons
10.1089/jir.1997.17.469 · 1997 · External reference
Induction of interferon-gamma in human leukocyte cultures stimulated by Zn2+
10.1016/0090-1229(87)90120-6 · 1987 · External reference
Zinc supplementation enhances the response to interferon therapy in patients with chronic hepatitis C
10.1046/j.1365-2893.2001.00311.x · 2001 · External reference
10.1073/pnas.2003138117
10.1073/pnas.2003138117 · External reference
Role of the ACE2/angiotensin 1–7 axis of the renin-angiotensin system in heart failure
10.1161/circresaha.116.307708 · 2016 · External reference
10.1002/mnfr.201500524
10.1002/mnfr.201500524 · External reference
Zinc supplement augments the suppressive effects of repurposed drugs of NF-kappa B inhibitor on ACE2 expression in human lung cell lines in vitro
2021 · External reference
Doses of chloroquine in the treatment of malaria by Plasmodium vivax in patients between 2 and 14 years of age from the Brazilian Amazon basin
10.1186/s12936-019-3072-8 · 2019 · External reference
Annals on call - COVID-19: is chloroquine the answer?
2020 · External reference
New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?
2020 · External reference
Chloroquine and hydroxychloroquine in covid-19
10.1136/bmj.m1432 · 2020 · External reference
Treating COVID-19 with chloroquine
2020 · External reference
The risk of QTc-interval prolongation in COVID-19 patients treated with chloroquine
10.1007/s12471-020-01462-6 · 2020 · External reference
Prophylactic (hydroxy)chloroquine in COVID-19: potential relevance for cardiac arrhythmia risk
10.1016/j.hrthm.2020.07.001 · 2020 · External reference
COVID-19 and (hydroxy)chloroquine-azithromycin combination: should we take the risk for our patients?
10.1111/bcp.14335 · 2020 · External reference
QTc prolongation risk evaluation in female COVID-19 patients undergoing chloroquine and hydroxychloroquine with/without azithromycin treatment
10.3389/fcvm.2020.00152 · 2020 · External reference
Benefit v. risk when using chloroquine in patients with severe COVID-19 disease
10.7196/samj.2020.v110i5.14761 · 2020 · External reference
10.1371/journal.pone.0109180
10.1371/journal.pone.0109180 · External reference
10.1101/2020.05.02.20080036
10.1101/2020.05.02.20080036 · External reference
Hydroxychloroquine and Covid-19: a cellular and molecular biology based update
10.1007/s12291-020-00900-x · 2020 · External reference
Chloroquine and hydroxychloroquine to treat COVID-19: between hope and caution
10.1080/15563650.2020.1748194 · 2021 · External reference
The efficacy and safety of hydroxychloroquine in patients with COVID-19: a multicenter national retrospective cohort
10.1007/s40121-021-00397-8 · 2021 · External reference
The rise and fall of hydroxychloroquine for the treatment and prevention of COVID-19
10.4269/ajtmh.20-1320 · 2021 · External reference
Reported adverse drug reactions associated with the use of hydroxychloroquine and chloroquine during the COVID-19 pandemic
2021 · External reference
10.1101/2021.01.19.427206
10.1101/2021.01.19.427206 · External reference
Exacerbation of antimicrobial resistance: another casualty of the COVID-19 pandemic?
2020 · External reference
Commentary: microbial resistance movements: an overview of global public health threats posed by antimicrobial resistance, and how best to counter
10.3389/fpubh.2020.629120 · 2020 · External reference
Implementation of antimicrobial stewardship to reduce antimicrobial drug resistance
2020 · External reference
Japan’s practical guidelines for zinc deficiency with a particular focus on taste disorders, inflammatory bowel disease, and liver cirrhosis
10.3390/ijms21082941 · 2020 · External reference
Zinc and its importance for human health: an integrative review
2013 · External reference
10.1177/15648265070283s303
10.1177/15648265070283s303 · External reference
10.1016/j.abb.2016.03.022
10.1016/j.abb.2016.03.022 · External reference
Nutrients and their role in host resistance to infection
10.1189/jlb.71.1.16 · 2002 · External reference
Intracellular zinc homeostasis in leukocyte subsets is regulated by different expression of zinc exporters ZnT-1 to ZnT-9
10.1189/jlb.0307148 · 2008 · External reference
10.1093/jn/130.5.1399s
10.1093/jn/130.5.1399s · External reference
10.1093/jn/137.5.1345
10.1093/jn/137.5.1345 · External reference
Preferential induction of apoptosis in mouse CD4+CD8+ alpha beta TCRloCD3 epsilon lo thymocytes by zinc
10.1002/jcp.1041640206 · 1995 · External reference
A reappraisal of the role of zinc in life and death decisions of cells
10.3181/00379727-215-44132 · 1997 · External reference
Effect of zinc supplementation on cell-mediated immunity and lymphocyte subsets in preschool children
1997 · External reference
10.1093/ajcn/68.2.447s
10.1093/ajcn/68.2.447s · External reference
Interference in the development of a secondary immune response in mice by zinc deprivation: persistence of effects
10.1093/jn/114.10.1762 · 1984 · External reference
Alteration of the immune and nutritional status of mice by synergy between zinc deficiency and infection with Trypanosoma cruzi
10.1093/jn/112.6.1224 · 1982 · External reference
10.1093/jn/114.1.170
10.1093/jn/114.1.170 · External reference
10.3390/ijms19030730
10.3390/ijms19030730 · External reference
10.1016/j.jnutbio.2018.09.011
10.1016/j.jnutbio.2018.09.011 · External reference
10.1093/intimm/dxq017
10.1093/intimm/dxq017 · External reference
Inflammatory response under zinc deficiency is exacerbated by dysfunction of the T helper type 2 lymphocyte-M2 macrophage pathway
10.1111/imm.13033 · 2019 · External reference
10.1155/2016/6762343
10.1155/2016/6762343 · External reference
10.1016/j.ebiom.2020.102763
10.1016/j.ebiom.2020.102763 · External reference
10.1101/2020.03.03.20030437
10.1101/2020.03.03.20030437 · External reference
10.1093/jn/130.5.1367s
10.1093/jn/130.5.1367s · External reference
Mineral intakes of elderly adult supplement and non-supplement users in the third national health and nutrition examination survey
10.1093/jn/132.11.3422 · 2002 · External reference
10.1016/j.ab.2006.02.009
10.1016/j.ab.2006.02.009 · External reference
Nutrient-gene interaction in ageing and successful ageing. A single nutrient (zinc) and some target genes related to inflammatory/immune response
2006 · External reference
Zinc and ageing (ZINCAGE Project)
10.1007/s10522-006-9044-8 · 2006 · External reference
Iron, copper, and zinc concentrations in normal skin and in various nonmalignant and malignant lesions
10.1111/j.1365-4362.1986.tb03449.x · 1986 · External reference
Trophic skin ulceration of leprosy: skin and serum zinc concentrations
10.1136/bmj.2.5918.531 · 1974 · External reference
Venous leg ulceration: skin and serum zinc concentrations
10.2340/000155555497498 · 1975 · External reference
Pharmaco-nutrient interactions - a systematic review of zinc and antihypertensive therapy
10.1111/ijcp.12040 · 2013 · External reference
10.2119/2008-00033.prasad
10.2119/2008-00033.prasad · External reference
Zinc supplementation decreases incidence of infections in the elderly: effect of zinc on generation of cytokines and oxidative stress
10.1093/ajcn/85.3.837 · 2007 · External reference
COVID-19 and the consequences of isolating the elderly
10.1016/s2468-2667(20)30061-x · 2020 · External reference
COVID-19 pandemic: palliative care for elderly and frail patients at home and in residential and nursing homes
10.4414/smw.2020.20235 · 2020 · External reference
Potential antioxidant effects of zinc and chromium supplementation in people with type 2 diabetes mellitus
10.1080/07315724.2001.10719034 · 2001 · External reference
Zinc supplementation promotes a Th1 response and improves clinical symptoms in fewer hours in children with pneumonia younger than 5 years old. A randomized controlled clinical trial
10.3389/fped.2019.00431 · 2019 · External reference
Prediction of survival odds in COVID-19 by zinc, age and selenoprotein P as composite biomarker
10.1016/j.redox.2020.101764 · 2021 · External reference
Treatment of SARS-CoV-2 with high dose oral zinc salts: a report on four patients
10.1016/j.ijid.2020.06.006 · 2020 · External reference
COVID-19: poor outcomes in patients with zinc deficiency
10.1016/j.ijid.2020.09.014 · 2020 · External reference
Effect of a combination of Nitazoxanide, Ribavirin and Ivermectin plus zinc supplement (MANS.NRIZ study) on the clearance of mild COVID-19
10.1002/jmv.26880 · 2021 · External reference
Treatment with zinc is associated with reduced in-hospital mortality among COVID-19 patients: a multi-center cohort study
2020 · External reference
10.1001/jamanetworkopen.2021.0369
10.1001/jamanetworkopen.2021.0369 · External reference
The minimal effect of zinc on the survival of hospitalized patients with COVID-19: an observational study
10.1016/j.chest.2020.06.082 · 2020 · External reference
Zinc toxicity
10.1093/ajcn/51.2.225 · 1990 · External reference
10.1007/s10534-015-9881-5
10.1007/s10534-015-9881-5 · External reference
COVID-19 pandemic: can boosting immune responses by maintaining adequate nutritional balance reduce viral insults?
10.4103/aihb.aihb_75_20 · 2020 · External reference
Do nutrients and other bioactive molecules from foods have anything to say in the treatment against COVID-19?
10.1016/j.envres.2020.110053 · 2020 · External reference
COVID-19 pandemic: impacts of social lockdown on nutritional health and beyond
10.4103/aihb.aihb_130_20 · 2021 · External reference
10.3390/nu12051466
10.3390/nu12051466 · External reference
Current state of evidence: influence of nutritional and nutrigenetic factors on immunity in the COVID-19 pandemic framework
10.3390/nu12092738 · 2020 · External reference
Optimal nutritional status for a well-functioning immune system is an important factor to protect against viral infections
10.3390/nu12041181 · 2020 · External reference
Nutritional support in coronavirus 2019 disease
10.3390/medicina56060289 · 2020 · External reference
Beyond transmission: dire need for integration of nutrition interventions in COVID-19 pandemic-response strategies in Developing Countries like Pakistan
10.12669/pjms.36.covid19-s4.2784 · 2020 · External reference
Zinc and respiratory tract infections: perspectives for COVID-19 (Review)
2020 · External reference
10.1007/s12011-020-02194-9
10.1007/s12011-020-02194-9 · External reference
Zinc as nutritional intervention and prevention measure for COVID-19 disease
10.1136/bmjnph-2020-000095 · 2020 · External reference
10.1016/j.ajo.2020.04.028
10.1016/j.ajo.2020.04.028 · External reference
COVID-19 pandemic: can maintaining optimal zinc balance enhance host resistance?
10.1620/tjem.251.175 · 2020 · External reference
Zinc for the prevention and treatment of SARS-CoV-2 and other acute viral respiratory infections: a rapid review
10.1016/j.aimed.2020.07.009 · 2020 · External reference
Serum concentrations of trace elements zinc, copper, selenium, and manganese in critically Ill patients
10.1007/s12011-018-1429-4 · 2019 · External reference
Zinc and COVID-19: basis of current clinical trials
2020 · External reference
Zinc ionophore activity of quercetin and epigallocatechin-gallate: from Hepa 1–6 cells to a liposome model
10.1021/jf5014633 · 2014 · External reference
Molecular and functional resemblance of dexamethasone and quercetin: a paradigm worth exploring in dexamethasone-nonresponsive COVID-19 patients
10.1002/ptr.6886 · 2020 · External reference
10.1016/j.autrev.2014.11.008
10.1016/j.autrev.2014.11.008 · External reference
10.1002/mawe.200290008
10.1002/mawe.200290008 · External reference
