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References from SARS-CoV-2 infection and smoking: What is the association? A brief review. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1038/s41586-020-2012-7
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Unresolved reference
External reference
10.1016/s1473-3099(20)30120-1
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10.1056/nejmc2004973
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Unresolved reference
External reference
10.1002/jmv.25748
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10.3390/jcm9030841
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Coronavirus (COVID-19): a review of clinical features, diagnosis
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Clinical characteristics of coronavirus disease 2019 in
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10.1111/all.14238
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COVID-19 and the nicotinic cholinergic system
10.1183/13993003.01589-2020 · 2020 · External reference
Smoking, ACE-2, and COVID-19: ongoing controversies
10.1183/13993003.01759-2020 · 2020 · External reference
10.1016/j.cell.2020.02.052
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10.1056/nejmp2005630
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COVID-19 and smoking: a systematic review and meta-analysis of the evidence
2021 · External reference
Determinants of personal exposure to some carcinogenic substances and nitrogen dioxide among the general population in five Swedish cities
10.1038/jes.2013.57 · 2014 · External reference
Tobacco smoke induces and alters immune responses in the lung triggering inflammation, allergy, asthma and other lung diseases: A Mechanistic review
10.3390/ijerph15051033 · 2018 · External reference
Tobacco smoking and COVID-19 infection
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High fatality rates and associated factors in two hospital outbreaks of MERS in Daejeon, the Republic of Korea
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The clinical and demographical profile of Coronavirus illness: The tale of Tablighi Jamaat and Zaireen in Quarantine/Isolation center at Sukkur and Hyderabad
10.12669/pjms.36.covid19-s4.2829 · 2020 · External reference
Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis
2020 · External reference
10.1016/s0140-6736(20)30566-3
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10.1097/cm9.0000000000000775
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Retrospective study on the epidemiological characteristics of 139 patients with novel coronavirus pneumonia on the effects of severity
2020 · External reference
10.1056/nejmoa2002032
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10.1016/s0140-6736(20)30183-5
10.1016/s0140-6736(20)30183-5 · External reference
The impact of COPD and smoking history on the severity of COVID-19: A systemic review and meta-analysis
10.1002/jmv.25889 · 2020 · External reference
Risk factors of critical & mortal COVID-19 cases: A systematic literature review and meta-analysis
10.1016/j.jinf.2020.04.021 · 2020 · External reference
Smoking is associated with COVID-19 progression: A meta-analysis
10.1093/ntr/ntaa082 · 2020 · External reference
Prevalence of underlying diseases in hospitalized patients with COVID-19: a systematic review and meta-analysis
2020 · External reference
Active smoking is not associated with severity of coronavirus disease 2019 (COVID-19)
10.1016/j.ejim.2020.03.014 · 2020 · External reference
Systematic review of the prevalence of current smoking among hospitalized COVID-19 patients in China: could nicotine be a therapeutic option?
10.1007/s11739-020-02355-7 · 2020 · External reference
Current smoking is not associated with COVID-19
10.1183/13993003.01290-2020 · 2020 · External reference
10.1016/j.devcel.2020.05.012
10.1016/j.devcel.2020.05.012 · External reference
Alternative roles of STAT3 and MAPK signaling pathways in the MMPs activation and progression of lung injury induced by cigarette smoke exposure in ACE2 knockout mice
10.7150/ijbs.13379 · 2016 · External reference
10.1016/j.burns.2015.04.010
10.1016/j.burns.2015.04.010 · External reference
10.1111/all.14429
10.1111/all.14429 · External reference
Smoking upregulates angiotensin-converting enzyme-2 receptor: A potential adhesion site for novel coronavirus SARS-CoV-2 (Covid-19)
10.3390/jcm9030841 · 2020 · External reference
Airways expression of SARS-CoV-2 receptor, ACE2, and TMPRSS2 Is lower in children than adults and increases with smoking and COPD
10.1016/j.omtm.2020.05.013 · 2020 · External reference
Multi-level immune response network in mild-moderate Chronic Obstructive Pulmonary Disease (COPD)
10.1186/s12931-019-1105-z · 2019 · External reference
Comprehensive analysis of transcriptome sequencing data in the lung tissues of COPD subjects
2015 · External reference
10.1172/jci.insight.131597
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10.3390/ijerph6010209
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Chronic obstructive pulmonary disease is associated with severe coronavirus disease 2019 (COVID-19)
10.1016/j.rmed.2020.105941 · 2020 · External reference
Gene expression profiling identifies MMP-12 and ADAMDEC1 as potential pathogenic mediators of pulmonary sarcoidosis
10.1164/rccm.200803-490oc · 2009 · External reference
An airway epithelial iNOS-DUOX2-thyroid peroxidase metabolome drives Th1/Th2 nitrative stress in human severe asthma
10.1038/mi.2014.6 · 2014 · External reference
Expression of SARS-CoV-2 entry receptors in the respiratory tract of healthy individuals, smokers and asthmatics
10.1186/s12931-020-01521-x · 2020 · External reference
10.1007/s11427-020-1643-8
10.1007/s11427-020-1643-8 · External reference
ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19
10.1183/13993003.00688-2020 · 2020 · External reference
10.1016/j.cell.2020.04.035
10.1016/j.cell.2020.04.035 · External reference
Variation in DNA-damage responses to an inhalational carcinogen (1,3-butadiene) in relation to strain-specific differences in chromatin accessibility and gene transcription profiles in C57BL/6J and CAST/EiJ mice
10.1289/ehp1937 · 2017 · External reference
Role of type II pneumocyte senescence in radiation-induced lung fibrosis
10.1093/jnci/djt212 · 2013 · External reference
10.1152/physiolgenomics.00208.2005
10.1152/physiolgenomics.00208.2005 · External reference
Chronic exposure to arsenic in the drinking water alters the expression of immune response genes in mouse lung
10.1289/ehp.0800199 · 2009 · External reference
Tobacco smoking increases the lung gene expression of ACE2, the receptor of SARS-CoV-2
10.1164/rccm.202003-0693le · 2020 · External reference
SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells
2020 · External reference
10.1006/bbrc.1999.2040
10.1006/bbrc.1999.2040 · External reference
HNF4α regulates claudin-7 protein expression during intestinal epithelial differentiation
10.1016/j.ajpath.2015.04.023 · 2015 · External reference
10.1016/s0079-6107(02)00037-8
10.1016/s0079-6107(02)00037-8 · External reference
10.1056/nejmra0910061
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10.1093/nar/gks1215
10.1093/nar/gks1215 · External reference
10.1016/j.cell.2009.12.018
10.1016/j.cell.2009.12.018 · External reference
Dynamics of ADAM17-mediated shedding of ACE2 applied to pancreatic islets of male db/db mice
10.1210/en.2015-1556 · 2015 · External reference
Smoking-mediated upregulation of the androgen pathway leads to increased SARS-CoV-2 susceptibility
10.3390/ijms21103627 · 2020 · External reference
Tobacco, but not nicotine and flavor-less electronic cigarettes, induces ACE2 and immune dysregulation
10.3390/ijms21155513 · 2020 · External reference
Is nicotine exposure linked to cardiopulmonary vulnerability to COVID-19 in the general population?
10.1111/febs.15303 · 2020 · External reference
COVID-19 and nicotine as a mediator of ACE-2
10.1183/13993003.01261-2020 · 2020 · External reference
COVID-19 and smoking: is nicotine the hidden link?
10.1183/13993003.01116-2020 · 2020 · External reference
Potential Immunoregulatory and Antiviral/SARS-CoV-2 Activities of Nitric Oxide
10.12659/msm.925679 · 2020 · External reference
Role of cigarette smoke on ACE-2 protein membrane expression in bronchial epithelial cells using an air-liquid interface model
2020 · External reference
Effect of inhaled nitric oxide on oxygen therapy, mechanical ventilation, and hypoxic respiratory failure
10.23736/s0026-4946.17.04944-1 · 2018 · External reference
Nitric oxide dosed in short bursts at high concentrations may protect against Covid 19
10.1016/j.niox.2020.06.005 · 2020 · External reference
10.1161/atvbaha.112.248559
10.1161/atvbaha.112.248559 · External reference
10.1186/2042-6410-1-6 · Admitted local publication
10.20944/preprints202002.0051.v3
10.20944/preprints202002.0051.v3 · External reference
10.1161/01.hyp.37.5.1199
10.1161/01.hyp.37.5.1199 · External reference
Gender differences in the renin-angiotensin and nitric oxide systems: relevance in the normal and diseased kidney
10.1159/000099150 · 2007 · External reference
Reporting on sex-based analysis in clinical trials of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker efficacy
2008 · External reference
Sex differences in the metabolic effects of the renin-angiotensin system
10.1186/s13293-019-0247-5 · 2019 · External reference
Could Sex/gender differences in ACE2 expression in the lungs contribute to the large gender disparity in the morbidity and mortality of patients infected with the SARS-CoV-2 Virus?
10.3389/fcimb.2020.00327 · 2020 · External reference
10.46234/ccdcw2020.032
10.46234/ccdcw2020.032 · External reference
Epidemiological characteristics of COVID-19 cases in non-Italian nationals notified to the Italian surveillance system
10.1093/eurpub/ckaa249 · 2021 · External reference
10.1152/ajplung.00391.2020
10.1152/ajplung.00391.2020 · External reference
Gender susceptibility to COVID-19: a review of the putative role of sex hormones and X chromosome
2020 · External reference
10.1002/ddr.21729
10.1002/ddr.21729 · External reference
Cigarette smoking has a positive and independent effect on testosterone levels
10.14310/horm.2002.1445 · 2013 · External reference
Evaluating MERS-CoV Entry Pathways
10.1007/978-1-0716-0211-9_2 · 2020 · External reference
Drug therapy. Pharmacologic aspects of cigarette smoking and nicotine addiction
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Acetaldehyde in mainstream tobacco smoke: formation and occurrence in smoke and bioavailability in the smoker
10.1021/tx020069f · 2002 · External reference
10.1016/s0272-5231(21)00813-3
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Effects of nonsteroidal anti-inflammatory drugs on the bronchial hyperresponsiveness of middle-aged male smokers
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Cigarette smoking increases bronchial mucosal IL-17A expression in asthmatics, which acts in concert with environmental aeroallergens to engender neutrophilic inflammation
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Effects of antioxidants on oxidative stress and inflammatory responses of human bronchial epithelial cells exposed to particulate matter and cigarette smoke extract
10.1016/j.tiv.2020.104883 · 2020 · External reference
Unresolved reference
External reference
Impact of smoking status on disease severity and mortality of hospitalized patients with COVID-19 infection: a systematic review and meta-analysis
10.1093/ntr/ntaa107 · 2020 · External reference
10.1183/13993003.01645-2020
10.1183/13993003.01645-2020 · External reference
10.1164/rccm.201708-1590oc
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Aerial transmission of the SARS-CoV-2 virus through environmental E-cigarette aerosols: implications for public policies
10.3390/ijerph18041437 · 2021 · External reference
Association between youth smoking, electronic cigarette use, and COVID-19
10.1016/j.jadohealth.2020.07.002 · 2020 · External reference
Associations between vaping and Covid-19: Cross-sectional findings from the HEBECO study
10.1016/j.drugalcdep.2021.108590 · 2021 · External reference
10.4081/hpr.2020.9124
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Review of trials currently testing treatment and prevention of COVID-19
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The serine protease inhibitor camostat inhibits influenza virus replication and cytokine production in primary cultures of human tracheal epithelial cells
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Camostat mesilate therapy for COVID-19
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Long-term impact of smoking on lung epithelial proliferation in current and former smokers
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Could the smoking gun in the fight against Covid-19 be the (rh) ACE2?
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Unresolved reference
External reference
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Efficacies of lopinavir/ritonavir and abidol in the treatment of novel coronavirus pneumonia
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