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References from Recognition of a tandem lesion by DNA bacterial formamidopyrimidine glycosylases explored combining molecular dynamics and machine learning. Local targets link to admitted publications; unresolved targets remain external evidence.
10.3390/ijms19040970
10.3390/ijms19040970 · External reference
Direct observation of damage clustering in irradiated DNA with atomic force microscopy
10.1093/nar/gkz1159 · 2020 · External reference
Radiation-induced clustered DNA lesions: Repair and mutagenesis
10.1016/j.freeradbiomed.2016.12.008 · 2017 · External reference
Oxidative DNA damage & repair: An introduction
10.1016/j.freeradbiomed.2017.02.017 · 2017 · External reference
10.1002/em.22087
10.1002/em.22087 · External reference
10.1016/0738-081x(85)90096-3
10.1016/0738-081x(85)90096-3 · External reference
10.1016/j.pharmthera.2016.02.003
10.1016/j.pharmthera.2016.02.003 · External reference
10.1038/s41391-019-0153-2
10.1038/s41391-019-0153-2 · External reference
10.1038/nature05978
10.1038/nature05978 · External reference
8-oxoguanine DNA damage: at the crossroad of alternative repair pathways
2003 · External reference
Characterization and mechanism of formation of tandem lesions in dna by a nucleobase peroxyl radical
10.1021/ja0692276 · 2007 · External reference
DNA base damage by reactive oxygen species, oxidizing agents, and uv radiation
10.1101/cshperspect.a012559 · 2013 · External reference
Radiation and hydrogen peroxide induced free radical damage to dna
1987 · External reference
10.1073/pnas.1000193107
10.1073/pnas.1000193107 · External reference
Induction and repair of clustered DNA lesions: What do we know so far?
10.1667/rr3041.1 · 2013 · External reference
Repair rate of clustered abasic DNA lesions by human endonuclease: Molecular bases of sequence specificity
10.1021/acs.jpclett.6b01692 · 2016 · External reference
Correlation of bistranded clustered abasic DNA lesion processing with structural and dynamic DNA helix distortion
10.1093/nar/gkw773 · 2016 · External reference
The mutagenic potential of 8-oxog/single strand break-containing clusters depends on their relative positions
2012 · External reference
Human DNA glycosylases of the bacterial fpg/mutm superfamily: an alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA
10.1093/nar/gkf618 · 2002 · External reference
Crystal structure of the lactococcus lactis formamidopyrimidine-DNA glycosylase bound to an abasic site analogue-containing DNA
10.1093/emboj/cdf304 · 2002 · External reference
Insights into the DNA repair process by the formamidopyrimidine-DNA glycosylase investigated by molecular dynamics
10.1110/ps.04772404 · 2004 · External reference
Global deformation facilitates flipping of damaged 8-oxo-guanine and guanine in DNA
2016 · External reference
10.1074/jbc.m109.069799
10.1074/jbc.m109.069799 · External reference
Mutm, a protein that prevents g c?t a transversions, is formamidopyrimidine-DNA glycosylase
10.1093/nar/19.13.3629 · 1991 · External reference
DNA lesion recognition by the bacterial repair enzyme mutm
10.1074/jbc.m307768200 · 2003 · External reference
Structural insights into lesion recognition and repair by the bacterial 8-oxoguanine DNA glycosylase mutm
2002 · External reference
10.1038/nature08561
10.1038/nature08561 · External reference
A dynamic checkpoint in oxidative lesion discrimination by formamidopyrimidine-DNA glycosylase
10.1093/nar/gkv1092 · 2015 · External reference
Emerging critical roles of fe–s clusters in dna replication and repair. Biochimica et Biophysica Acta (BBA)-Molecular
1853 · External reference
Fe-s clusters and muty base excision repair glycosylases: Purification, kinetics, and dna affinity measurements
10.1016/bs.mie.2017.11.035 · 2018 · External reference
10.1021/bi800950t
10.1021/bi800950t · External reference
Molecular dynamics simulation of clustered DNA damage sites containing 8-oxoguanine and abasic site
10.1002/jcc.20184 · 2005 · External reference
Mechanical evolution of DNA double-strand breaks in the nucleosome
10.1371/journal.pcbi.1006224 · 2018 · External reference
Multiply damaged sites in DNA: Interactions with Escherichia coli endonucleases III and VIII
10.1093/nar/26.4.932 · 1998 · External reference
Induction and repair of clustered dna lesions: what do we know so far?
10.1667/rr3041.1 · 2013 · External reference
The influence of (5’ r)-and (5’ s)-5’, 8-cyclo-2’-deoxyadenosine on udg and hape1 activity. tandem lesions are the base excision repair system’s nightmare
10.3390/cells8111303 · 2019 · External reference
The influence of single, tandem, and clustered dna damage on the electronic properties of the double helix: A theoretical study
10.3390/molecules25143126 · 2020 · External reference
Efficiency of repair of an abasic site within dna clustered damage sites by mammalian cell nuclear extracts
10.1021/bi049560r · 2004 · External reference
10.1021/ar2001217
10.1021/ar2001217 · External reference
Functional flexibility of bacillus stearothermophilus formamidopyrimidine DNA-glycosylase
10.1016/j.dnarep.2006.05.042 · 2006 · External reference
10.1002/1873-3468.13876
10.1002/1873-3468.13876 · External reference
10.1016/j.bpj.2019.12.016
10.1016/j.bpj.2019.12.016 · External reference
10.1074/jbc.m202058200
10.1074/jbc.m202058200 · External reference
10.1002/ange.201403334
10.1002/ange.201403334 · External reference
Base-independent dna base-excision repair of 8-oxoguanine
10.1021/jacs.7b11254 · 2018 · External reference
10.1002/anie.201403334
10.1002/anie.201403334 · External reference
10.1021/jacs.7b11254
10.1021/jacs.7b11254 · External reference
10.1093/nar/gkp608
10.1093/nar/gkp608 · External reference
10.1021/bi100593a
10.1021/bi100593a · External reference
Crystal structure of a repair enzyme of oxidatively damaged DNA, mutm (fpg), from an extreme thermophile, thermus thermophilus hb8
10.1093/emboj/19.15.3857 · 2000 · External reference
Solution-state nmr investigation of DNA binding interactions in escherichia coli formamidopyrimidine-DNA glycosylase (fpg): a dynamic description of the DNA/protein interface
10.1016/j.dnarep.2004.09.012 · 2005 · External reference
Recent advances in the structural mechanisms of DNA glycosylases
1834 · External reference
Two glycosylase families diffusively scan DNA using a wedge residue to probe for and identify oxidatively damaged bases
10.1073/pnas.1400386111 · 2014 · External reference
Spectrum of radiation-induced clustered non-DSB damage – A Monte Carlo track structure modeling and calculations
10.1667/rr13902.1 · 2015 · External reference
8-OxoG retards the activity of the ligase III/XRCC1 complex during the repair of a single-strand break, when present within a clustered DNA damage site
10.1016/j.dnarep.2003.11.006 · 2004 · External reference
10.1021/bi00482a011
10.1021/bi00482a011 · External reference
Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-oxoguanine in DNA induces targeted GC –> TA transversions in simian kidney cells
10.1073/pnas.90.3.1122 · 1993 · External reference
10.1016/j.radonc.2013.06.013
10.1016/j.radonc.2013.06.013 · External reference
10.1016/j.mrrev.2012.06.002
10.1016/j.mrrev.2012.06.002 · External reference
10.7150/ijms.3635
10.7150/ijms.3635 · External reference
DNA sequence context effects on the glycosylase activity of human 8-oxoguanine DNA glycosylase
10.1074/jbc.m112.397786 · 2012 · External reference
Understanding the sequence and structural context effects in oxidative DNA damage repair
10.1016/j.dnarep.2020.102906 · 2020 · External reference
Unresolved reference
External reference
Comparative protein structure modeling using modeller
10.1002/cpbi.3 · 2016 · External reference
Structural survey of zinc-containing proteins and development of the zinc amber force field (zaff)
10.1021/ct1002626 · 2010 · External reference
10.1021/acs.jctc.5b00255
10.1021/acs.jctc.5b00255 · External reference
Parmbsc1: a refined force field for DNA simulations
10.1038/nmeth.3658 · 2016 · External reference
Interstrand cross-linking implies contrasting structural consequences for dna: insights from molecular dynamics
2017 · External reference
Nucleosomal embedding reshapes the dynamics of abasic sites
10.1038/s41598-020-73997-y · 2020 · External reference
Singlet oxygen attack on guanine: Reactivity and structural signature within the B-DNA helix. Chemistry–A
10.1002/chem.201601287 · 2016 · External reference
10.1007/978-0-387-98141-3
10.1007/978-0-387-98141-3 · External reference
10.1016/0263-7855(96)00018-5
10.1016/0263-7855(96)00018-5 · External reference
