Research graph
References from Recent advances in functional annotation and prediction of the epitranscriptome. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1038/nature12730
10.1038/nature12730 · External reference
Dynamic m(6)A mRNA methylation directs translational control of heat shock response
10.1038/nature15377 · 2015 · External reference
10.1016/j.cell.2015.05.014
10.1016/j.cell.2015.05.014 · External reference
10.1016/j.cell.2017.03.031
10.1016/j.cell.2017.03.031 · External reference
10.1016/j.molcel.2016.01.012
10.1016/j.molcel.2016.01.012 · External reference
10.1016/j.chom.2019.07.005
10.1016/j.chom.2019.07.005 · External reference
10.1093/nar/gkx1030
10.1093/nar/gkx1030 · External reference
10.1002/wrna.1595
10.1002/wrna.1595 · External reference
A molecular-level perspective on the frequency, distribution, and consequences of messenger RNA modifications
10.1002/wrna.1586 · 2020 · External reference
10.1038/nchembio.687
10.1038/nchembio.687 · External reference
10.1038/nature11112
10.1038/nature11112 · External reference
10.1016/j.cell.2012.05.003
10.1016/j.cell.2012.05.003 · External reference
10.1186/gb-2012-13-10-175
10.1186/gb-2012-13-10-175 · External reference
10.1016/j.cell.2013.10.047
10.1016/j.cell.2013.10.047 · External reference
10.1016/j.cell.2017.05.045
10.1016/j.cell.2017.05.045 · External reference
5' UTR m(6)A promotes cap-independent translation
10.1016/j.cell.2015.10.012 · 2015 · External reference
10.1038/s41580-019-0168-5
10.1038/s41580-019-0168-5 · External reference
10.1073/pnas.1820574116
10.1073/pnas.1820574116 · External reference
10.1016/j.molcel.2012.10.015
10.1016/j.molcel.2012.10.015 · External reference
HNRNPA2B1 Is a Mediator of m(6)A-Dependent Nuclear RNA Processing Events
10.1016/j.cell.2015.08.011 · 2015 · External reference
10.1038/nature14234
10.1038/nature14234 · External reference
10.1038/nature21355
10.1038/nature21355 · External reference
10.1016/j.stem.2014.09.019
10.1016/j.stem.2014.09.019 · External reference
10.1126/science.1261417
10.1126/science.1261417 · External reference
10.1038/nature25784
10.1038/nature25784 · External reference
10.1038/s41556-019-0319-0
10.1038/s41556-019-0319-0 · External reference
10.1016/j.cell.2013.10.026
10.1016/j.cell.2013.10.026 · External reference
Posttranscriptional m(6)A Editing of HIV-1 mRNAs enhances viral gene expression
10.1016/j.chom.2017.11.010 · 2017 · External reference
Viral and cellular N(6)-methyladenosine and N(6),2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle
10.1038/s41564-017-0056-8 · 2018 · External reference
mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis
10.1038/s41586-018-0538-8 · 2018 · External reference
10.1038/s41586-019-0916-x
10.1038/s41586-019-0916-x · External reference
10.1038/nature24678
10.1038/nature24678 · External reference
10.1126/science.aax4468
10.1126/science.aax4468 · External reference
10.1038/nature23450
10.1038/nature23450 · External reference
10.1016/j.cell.2017.09.003
10.1016/j.cell.2017.09.003 · External reference
Integrating genome-wide association study and methylation functional annotation data identified candidate genes and pathways for schizophrenia
10.1016/j.pnpbp.2019.109736 · 2020 · External reference
Cross-Talk between Dnmt2-Dependent tRNA Methylation and Queuosine Modification
10.3390/biom7010014 · 2017 · External reference
10.1038/nsmb.2357
10.1038/nsmb.2357 · External reference
5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader
10.1038/cr.2017.55 · 2017 · External reference
10.1016/j.molcel.2019.06.033
10.1016/j.molcel.2019.06.033 · External reference
10.1038/s41556-019-0361-y
10.1038/s41556-019-0361-y · External reference
10.1146/annurev-biochem-060208-105251
10.1146/annurev-biochem-060208-105251 · External reference
10.1016/j.ccell.2015.08.013
10.1016/j.ccell.2015.08.013 · External reference
10.1074/jbc.tm118.004166
10.1074/jbc.tm118.004166 · External reference
10.1016/j.brainres.2013.12.011
10.1016/j.brainres.2013.12.011 · External reference
10.1016/j.jaut.2019.102329
10.1016/j.jaut.2019.102329 · External reference
Regulation of mRNA cap methylation
10.1042/bj20091352 · 2009 · External reference
Interactions between fission yeast mRNA capping enzymes and elongation factor Spt5
10.1074/jbc.m200015200 · 2002 · External reference
Recognition of cap structure in splicing in vitro of mRNA precursors
10.1016/0092-8674(84)90268-x · 1984 · External reference
5′-Terminal 7-methylguanosine in eukaryotic mRNA is required for translation
10.1038/255033a0 · 1975 · External reference
m6A-Atlas: a comprehensive knowledgebase for unraveling the N6-methyladenosine (m6A) epitranscriptome
10.1093/nar/gkaa692 · 2021 · External reference
REPIC: a database for exploring the N(6)-methyladenosine methylome
10.1186/s13059-020-02012-4 · 2020 · External reference
10.1093/nar/gkx934
10.1093/nar/gkx934 · External reference
10.1093/nar/gkx1080
10.1093/nar/gkx1080 · External reference
The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence dependent
2015 · External reference
10.1038/nature13802
10.1038/nature13802 · External reference
CoverageAnalyzer (CAn): A tool for inspection of modification signatures in RNA sequencing profiles
10.3390/biom6040042 · 2016 · External reference
10.1261/rna.036806.112
10.1261/rna.036806.112 · External reference
Graphical workflow system for modification calling by machine learning of reverse transcription signatures
10.3389/fgene.2019.00876 · 2019 · External reference
10.3390/genes10010035
10.3390/genes10010035 · External reference
Characterizing 5-methylcytosine in the mammalian epitranscriptome
10.1186/gb4143 · 2013 · External reference
10.1101/gad.586710
10.1101/gad.586710 · External reference
Formation and abundance of 5-hydroxymethylcytosine in RNA
2015 · External reference
10.1038/s41594-019-0218-x
10.1038/s41594-019-0218-x · External reference
Distinct 5-methylcytosine profiles in poly(A) RNA from mouse embryonic stem cells and brain
10.1186/s13059-016-1139-1 · 2017 · External reference
10.1371/journal.pgen.1003602
10.1371/journal.pgen.1003602 · External reference
10.1261/rna.069112.118
10.1261/rna.069112.118 · External reference
10.1093/nar/gkw104
10.1093/nar/gkw104 · External reference
WHISTLE: a high-accuracy map of the human N6-methyladenosine (m6A) epitranscriptome predicted using a machine learning approach
10.1093/nar/gkz074 · 2019 · External reference
Iterative feature representation algorithm to improve the predictive performance of N7-methylguanosine sites
2020 · External reference
10.1093/bib/bbz112
10.1093/bib/bbz112 · External reference
PEA: an integrated R toolkit for plant epitranscriptome analysis
10.1093/bioinformatics/bty421 · 2018 · External reference
10.1093/bioinformatics/btz358
10.1093/bioinformatics/btz358 · External reference
m7GHub: deciphering the location, regulation and pathogenesis of internal mRNA N7-methylguanosine (m7G) sites in human
10.1093/bioinformatics/btaa178 · 2020 · External reference
iMRM: a platform for simultaneously identifying multiple kinds of RNA modifications
10.1093/bioinformatics/btaa155 · 2020 · External reference
PPUS: a web server to predict PUS-specific pseudouridine sites
10.1093/bioinformatics/btv366 · 2015 · External reference
m6AmPred: Identifying RNA N6, 2’-O-dimethyladenosine (m6Am) sites based on sequence-derived information
2021 · External reference
Prediction of RNA methylation status from gene expression data using classification and regression methods
2020 · External reference
PIANO: A web server for pseudouridine-Site (Psi) identification and functional annotation
10.3389/fgene.2020.00088 · 2020 · External reference
PSI-MOUSE: Predicting mouse pseudouridine sites from sequence and genome-derived features
10.1177/1176934320925752 · 2020 · External reference
10.2174/1389202921666200211104140
10.2174/1389202921666200211104140 · External reference
ISGm1A: Integration of sequence features and genomic features to improve the prediction of human m1A RNA Methylation Sites
10.1109/access.2020.2991070 · 2020 · External reference
LITHOPHONE: Improving lncRNA methylation site prediction using an ensemble predictor
10.3389/fgene.2020.00545 · 2020 · External reference
m5UPred: A Web Server for the Prediction of RNA 5-Methyluridine Sites from Sequences
10.1016/j.omtn.2020.09.031 · 2020 · External reference
10.1016/j.cell.2012.05.003
10.1016/j.cell.2012.05.003 · External reference
10.1186/gb-2008-9-9-r137
10.1186/gb-2008-9-9-r137 · External reference
Transcriptome-wide mapping of N(6)-methyladenosine by m(6)A-seq based on immunocapturing and massively parallel sequencing
10.1038/nprot.2012.148 · 2013 · External reference
Modeling of RNA-seq fragment sequence bias reduces systematic errors in transcript abundance estimation
10.1038/nbt.3682 · 2016 · External reference
10.1093/bioinformatics/btt171
10.1093/bioinformatics/btt171 · External reference
10.1093/bioinformatics/btw281
10.1093/bioinformatics/btw281 · External reference
REPIC: a database for exploring the N-6-methyladenosine methylome
2020 · External reference
Evaluation of different computational methods on 5-methylcytosine sites identification
2019 · External reference
10.1016/j.csbj.2020.06.010 · Admitted local publication
10.1016/j.ab.2015.08.021
10.1016/j.ab.2015.08.021 · External reference
DeepM6ASeq: prediction and characterization of m6A-containing sequences using deep learning
10.1186/s12859-018-2516-4 · 2018 · External reference
Global analysis of N6-methyladenosine functions and its disease association using deep learning and network-based methods
10.1371/journal.pcbi.1006663 · 2019 · External reference
PIANO: A Web Server for Pseudouridine-Site (Psi) Identification and Functional Annotation
10.3389/fgene.2020.00088 · 2020 · External reference
MeTDiff: A novel differential RNA Methylation Analysis for MeRIP-Seq Data
10.1109/tcbb.2015.2403355 · 2018 · External reference
DRME: Count-based differential RNA methylation analysis at small sample size scenario
10.1016/j.ab.2016.01.014 · 2016 · External reference
QNB: differential RNA methylation analysis for count-based small-sample sequencing data with a quad-negative binomial model
10.1186/s12859-017-1808-4 · 2017 · External reference
10.1186/s13059-019-1915-9
10.1186/s13059-019-1915-9 · External reference
10.1093/bioinformatics/btz316
10.1093/bioinformatics/btz316 · External reference
10.1093/bioinformatics/btaa066
10.1093/bioinformatics/btaa066 · External reference
Limits in the detection of m(6)A changes using MeRIP/m(6)A-seq
10.1038/s41598-020-63355-3 · 2020 · External reference
10.1016/j.jgg.2020.07.003
10.1016/j.jgg.2020.07.003 · External reference
10.1093/nar/gkq1028
10.1093/nar/gkq1028 · External reference
m6AVar: a database of functional variants involved in m6A modification
10.1093/nar/gkx895 · 2018 · External reference
CVm6A: A Visualization and Exploration Database for m(6)As in Cell Lines
2019 · External reference
M6A2Target: a comprehensive database for targets of m6A writers, erasers and readers
2020 · External reference
10.1093/nar/gkt996
10.1093/nar/gkt996 · External reference
10.1093/nar/gkw767
10.1093/nar/gkw767 · External reference
10.1093/nar/gkx120
10.1093/nar/gkx120 · External reference
RNAmod: an integrated system for the annotation of mRNA modifications
10.1093/nar/gkz479 · 2019 · External reference
10.1155/2016/8367534
10.1155/2016/8367534 · External reference
10.1371/journal.pcbi.1005287
10.1371/journal.pcbi.1005287 · External reference
A brief review of RNA modification related database resources
2021 · External reference
10.1038/srep14941
10.1038/srep14941 · External reference
10.1093/nar/gks961
10.1093/nar/gks961 · External reference
10.1093/nar/gkq603
10.1093/nar/gkq603 · External reference
10.4161/fly.19695
10.4161/fly.19695 · External reference
Detailed modeling of positive selection improves detection of cancer driver genes
10.1038/s41467-019-11284-9 · 2019 · External reference
10.1016/j.cell.2017.11.031
10.1016/j.cell.2017.11.031 · External reference
m6ASNP: a tool for annotating genetic variants by m6A function
10.1093/gigascience/giy035 · 2018 · External reference
10.1093/nar/29.1.308
10.1093/nar/29.1.308 · External reference
10.1038/nmeth.3453
10.1038/nmeth.3453 · External reference
10.1101/gad.269415.115
10.1101/gad.269415.115 · External reference
High-resolution N(6) -methyladenosine (m(6) A) map using photo-crosslinking-assisted m(6) A sequencing
10.1002/anie.201410647 · 2015 · External reference
10.1093/nar/gkt1248
10.1093/nar/gkt1248 · External reference
An open access database of genome-wide association results
10.1186/1471-2350-10-6 · 2009 · External reference
10.1093/nar/gkaa811
10.1093/nar/gkaa811 · External reference
10.1093/nar/gkaa790
10.1093/nar/gkaa790 · External reference
10.1093/bioinformatics/btv722
10.1093/bioinformatics/btv722 · External reference
10.1038/s41588-020-0644-z
10.1038/s41588-020-0644-z · External reference
10.1038/nmeth.3810
10.1038/nmeth.3810 · External reference
10.1038/nature12946
10.1038/nature12946 · External reference
10.1038/ng.3506
10.1038/ng.3506 · External reference
10.1038/s41588-019-0385-z
10.1038/s41588-019-0385-z · External reference
Recognition of RNA N-6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation
10.1038/s41556-020-00580-y · 2020 · External reference
Cross-talk among writers, readers, and erasers of m(6)A regulates cancer growth and progression
10.1126/sciadv.aar8263 · 2018 · External reference
m(6)A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program
10.1016/j.ccell.2017.02.013 · 2017 · External reference
10.1016/j.bbagrm.2018.09.010
10.1016/j.bbagrm.2018.09.010 · External reference
Funm6AViewer: a web server and R package for functional analysis of context-specific m6A RNA methylation
2021 · External reference
m6Acomet: large-scale functional prediction of individual m(6)A RNA methylation sites from an RNA co-methylation network
10.1186/s12859-019-2840-3 · 2019 · External reference
ConsRM: a centralized platform for conservation analysis and functional prioritization of individual RNA methylation sites
2021 · External reference
DRUM: Inference of Disease-Associated m(6)A RNA Methylation Sites From a Multi-Layer Heterogeneous Network
10.3389/fgene.2019.00266 · 2019 · External reference
HN-CNN: A heterogeneous network based on convolutional neural network for m(7) G Site Disease Association Prediction
10.3389/fgene.2021.655284 · 2021 · External reference
m(7)GDisAI: N7-methylguanosine (m(7)G) sites and diseases associations inference based on heterogeneous network
10.1186/s12859-021-04007-9 · 2021 · External reference
Integrative genomic analysis predicts regulatory role of N (6)-Methyladenosine-Associated SNPs for Adiposity
10.3389/fcell.2020.00551 · 2020 · External reference
Genome-wide identification of m(6)A-associated single-nucleotide polymorphisms in Parkinson's disease
10.1016/j.neulet.2020.135315 · 2020 · External reference
Decomposition of RNA methylome reveals co-methylation patterns induced by latent enzymatic regulators of the epitranscriptome
10.1039/c4mb00604f · 2015 · External reference
Enhancing Epitranscriptome Module Detection from m(6)A-Seq Data using threshold-based measurement weighting strategy
2018 · External reference
10.1109/tcbb.2021.3049366
10.1109/tcbb.2021.3049366 · External reference
REW-ISA: unveiling local functional blocks in epi-transcriptome profiling data via an RNA expression-weighted iterative signature algorithm
10.1186/s12859-020-03787-w · 2020 · External reference
10.1109/jbhi.2021.3068783
10.1109/jbhi.2021.3068783 · External reference
10.1016/j.celrep.2017.02.059
10.1016/j.celrep.2017.02.059 · External reference
10.1016/j.ccell.2017.02.013
10.1016/j.ccell.2017.02.013 · External reference
10.1016/j.molcel.2016.03.021
10.1016/j.molcel.2016.03.021 · External reference
10.18632/oncotarget.11743
10.18632/oncotarget.11743 · External reference
RNAMethyPro: a biologically conserved signature of N6-methyladenosine regulators for predicting survival at pan-cancer level
10.1038/s41698-019-0085-2 · 2019 · External reference
10.1038/ncomms3612
10.1038/ncomms3612 · External reference
Molecular characterization and clinical relevance of m(6)A regulators across 33 cancer types
10.1186/s12943-019-1066-3 · 2019 · External reference
Gene signatures and prognostic values of m1A-related regulatory genes in hepatocellular carcinoma
10.1038/s41598-020-72178-1 · 2020 · External reference
Prognostic Value of an m6A RNA methylation regulator-based signature in patients with hepatocellular carcinoma
10.1155/2020/2053902 · 2020 · External reference
The prognostic values of m6A RNA methylation regulators in uveal melanoma
10.1186/s12885-020-07159-8 · 2020 · External reference
The m6A methylation regulator-based signature for predicting the prognosis of prostate cancer
10.2217/fon-2020-0330 · 2020 · External reference
10.1089/dna.2020.5624
10.1089/dna.2020.5624 · External reference
Construction and Validation of an m6A RNA methylation regulators-based prognostic signature for esophageal cancer
10.2147/cmar.s254870 · 2020 · External reference
Prognostic values of m6A RNA methylation regulators in differentiated Thyroid Carcinoma
10.7150/jca.41193 · 2020 · External reference
Identification of a m(6)A RNA methylation regulators-based signature for predicting the prognosis of clear cell renal carcinoma
10.1186/s12935-020-01238-3 · 2020 · External reference
10.1016/j.omto.2020.04.011
10.1016/j.omto.2020.04.011 · External reference
N6-Methylandenosine-Related lncRNAs are potential biomarkers for predicting the overall survival of lower-grade glioma patients
10.3389/fcell.2020.00642 · 2020 · External reference
10.1038/ncomms12626
10.1038/ncomms12626 · External reference
10.1186/s13059-014-0550-8
10.1186/s13059-014-0550-8 · External reference
10.1093/nar/gkx778
10.1093/nar/gkx778 · External reference
10.1016/j.molcel.2017.10.002
10.1016/j.molcel.2017.10.002 · External reference
10.1126/science.aay6018
10.1126/science.aay6018 · External reference
10.1038/s41593-017-0057-1
10.1038/s41593-017-0057-1 · External reference
10.1016/j.gpb.2018.12.007
10.1016/j.gpb.2018.12.007 · External reference
10.1038/s41586-018-0841-4
10.1038/s41586-018-0841-4 · External reference
m6A RNA methylation regulates the fate of endogenous retroviruses
10.1038/s41586-020-03135-1 · 2021 · External reference
10.1016/j.ymeth.2018.10.019
10.1016/j.ymeth.2018.10.019 · External reference
Deciphering nucleotide modification-induced structure and stability changes
2021 · External reference
RNA secondary structure dependence in METTL3-METTL14 mRNA methylation is modulated by the N-terminal domain of METTL3
10.1515/hsz-2020-0265 · 2020 · External reference
10.1093/nar/gkaa654
10.1093/nar/gkaa654 · External reference
10.1101/2020.05.28.121996
10.1101/2020.05.28.121996 · External reference
MetaTX: deciphering the distribution of mRNA-related features in the presence of isoform ambiguity, with applications in epitranscriptome analysis
2020 · External reference
10.1093/bioinformatics/btz900
10.1093/bioinformatics/btz900 · External reference
Quantitative profiling of N(6)-methyladenosine at single-base resolution in stem-differentiating xylem of Populus trichocarpa using Nanopore direct RNA sequencing
10.1186/s13059-020-02241-7 · 2021 · External reference
Direct RNA sequencing reveals m(6)A modifications on adenovirus RNA are necessary for efficient splicing
10.1038/s41467-020-19787-6 · 2020 · External reference
Nanopore direct RNA sequencing maps the complexity of Arabidopsis mRNA processing and m(6)A modification
10.7554/elife.49658 · 2020 · External reference
Decoding the epitranscriptional landscape from native RNA sequences
2020 · External reference
Direct RNA nanopore sequencing of full-length coronavirus genomes provides novel insights into structural variants and enables modification analysis
10.1101/gr.247064.118 · 2019 · External reference
Single-molecule sequencing detection of N6-methyladenine in microbial reference materials
10.1038/s41467-019-08289-9 · 2019 · External reference
Accurate detection of m(6)A RNA modifications in native RNA sequences
10.1038/s41467-019-11713-9 · 2019 · External reference