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References from Gene-metabolite networks associated with impediment of bone fracture repair in spaceflight. Local targets link to admitted publications; unresolved targets remain external evidence.
A simulated weightlessness state diminishes cortical bone healing responses
2006 · External reference
Skeletal responses to space flight and the bed rest analog: a review
2007 · External reference
The effects of spaceflight and fracture healing on distant skeletal sites
10.1038/s41598-019-47695-3 · 2019 · External reference
Skeletal adaptations in young male mice after 4 weeks aboard the International Space Station
10.1038/s41526-019-0081-4 · 2019 · External reference
Bone mineral and lean tissue loss after long duration space flight
2000 · External reference
Russian system of countermeasures on board of the International Space Station (ISS): the first results
10.1016/j.actaastro.2004.05.049 · 2004 · External reference
An integrated omics analysis: impact of microgravity on host response to lipopolysaccharide in vitro
10.1186/1471-2164-15-659 · 2014 · External reference
Gene-metabolite profile integration to understand the cause of spaceflight induced immunodeficiency
10.1038/s41526-017-0038-4 · 2018 · External reference
10.1002/jbmr.4102
10.1002/jbmr.4102 · External reference
10.1038/nrrheum.2014.164
10.1038/nrrheum.2014.164 · External reference
10.1126/science.aau8650
10.1126/science.aau8650 · External reference
Reduction in proximal femoral strength due to long-duration spaceflight
10.1016/j.bone.2008.11.014 · 2009 · External reference
Cortical and trabecular bone mineral loss from the spine and hip in long-duration spaceflight
10.1359/jbmr.040307 · 2004 · External reference
Effects of long-term microgravity exposure on cancellous and cortical weight-bearing bones of cosmonauts
10.1016/s0140-6736(00)02217-0 · 2000 · External reference
10.1002/j.2040-4603.2016.tb00686.x
10.1002/j.2040-4603.2016.tb00686.x · External reference
Development and validation of a predictive bone fracture risk model for astronauts
10.1007/s10439-009-9779-x · 2009 · External reference
Fracture healing: the diamond concept
10.1016/s0020-1383(08)70003-2 · 2007 · External reference
10.1016/s0020-1383(08)70007-x
10.1016/s0020-1383(08)70007-x · External reference
The treatment of nonunions following intramedullary nailing of femoral shaft fractures
10.1097/00005131-200207000-00005 · 2002 · External reference
Staged bone grafting for the management of segmental long bone defects caused by trauma or infection using induced-membrane technique
2018 · External reference
10.1097/bot.0000000000000700
10.1097/bot.0000000000000700 · External reference
10.1002/jor.23845
10.1002/jor.23845 · External reference
Unresolved reference
2001 · External reference
Characterization of a reproducible model of fracture healing in mice using an open femoral osteotomy
10.1016/j.bonr.2020.100250 · 2020 · External reference
10.1016/j.injury.2020.04.011
10.1016/j.injury.2020.04.011 · External reference
Unresolved reference
2013 · External reference
10.1007/978-90-481-9075-1_36
10.1007/978-90-481-9075-1_36 · External reference
Forces associated with launch into space do not impact bone fracture healing
2018 · External reference
Cohousing male mice with and without segmental bone defects
2018 · External reference
10.1016/j.lssr.2018.03.002
10.1016/j.lssr.2018.03.002 · External reference
Skeletal adaptations in young male mice after 4 weeks aboard the International Space Station
10.1038/s41526-019-0081-4 · 2019 · External reference
The effects of spaceflight and fracture healing on distant skeletal sites
10.1038/s41598-019-47695-3 · 2019 · External reference
10.1016/j.biomaterials.2006.09.004
10.1016/j.biomaterials.2006.09.004 · External reference
10.1016/j.biomaterials.2006.09.004
10.1016/j.biomaterials.2006.09.004 · External reference
Unresolved reference
External reference
Unresolved reference
External reference
Unresolved reference
External reference
10.1097/bot.0b013e3181ed1349
10.1097/bot.0b013e3181ed1349 · External reference
10.1097/bot.0b013e31822588d8
10.1097/bot.0b013e31822588d8 · External reference
Unresolved reference
External reference
10.1002/jbmr.141
10.1002/jbmr.141 · External reference
The radiographic union scale in tibial fractures: reliability and validity
10.1097/bot.0b013e3181ca3fd1 · 2010 · External reference
Development of the radiographic union score for tibial fractures for the assessment of tibial fracture healing after intramedullary fixation
2010 · External reference
The responses of lungs and adjacent lymph nodes in responding to Yersinia pestis infection: a transcriptomic study using a non-human primate model
10.1371/journal.pone.0209592 · 2019 · External reference
Contributions of polyunsaturated fatty acids (PUFA) on cerebral neurobiology: an integrated omics approach with epigenomic focus
10.1016/j.jnutbio.2016.12.006 · 2017 · External reference
Optimized LOWESS normalization parameter selection for DNA microarray data
10.1186/1471-2105-5-194 · 2004 · External reference
Transcriptomic analysis of the effects of a fish oil enriched diet on murine brains
10.1371/journal.pone.0090425 · 2014 · External reference
10.1006/meth.2001.1262
10.1006/meth.2001.1262 · External reference
Gene-metabolite profile integration to understand the cause of spaceflight induced immunodeficiency
10.1038/s41526-017-0038-4 · 2018 · External reference
10.1002/jnr.24229
10.1002/jnr.24229 · External reference
micro RNA and metabolite signatures linked to early consequences of lethal radiation
10.1038/s41598-020-62255-w · 2020 · External reference
Unresolved reference
External reference
10.1359/jbmr.060509
10.1359/jbmr.060509 · External reference
10.1016/j.lfs.2015.10.025
10.1016/j.lfs.2015.10.025 · External reference
10.1016/j.copbio.2014.12.007
10.1016/j.copbio.2014.12.007 · External reference
Osteocyte apoptosis caused by hindlimb unloading is required to trigger osteocyte RANKL production and subsequent resorption of cortical and trabecular bone in mice femurs
10.1002/jbmr.2807 · 2016 · External reference
10.1074/jbc.m115.642090
10.1074/jbc.m115.642090 · External reference
10.1359/jbmr.060107
10.1359/jbmr.060107 · External reference
Regeneration of injured skeletal muscle after the injury
10.32098/mltj.04.2013.16 · 2013 · External reference
Bone fracture healing in mechanobiological modeling: a review of principles and methods
10.1016/j.bonr.2017.03.002 · 2017 · External reference
10.1016/j.abb.2014.07.006
10.1016/j.abb.2014.07.006 · External reference
10.1007/s00018-018-2913-x
10.1007/s00018-018-2913-x · External reference
10.1111/j.1476-5381.2008.00095.x
10.1111/j.1476-5381.2008.00095.x · External reference
10.1242/jcs.115.15.3039
10.1242/jcs.115.15.3039 · External reference
10.4161/cam.5.2.14403
10.4161/cam.5.2.14403 · External reference
10.1016/s0165-6147(00)01596-0
10.1016/s0165-6147(00)01596-0 · External reference
10.1242/jcs.031286
10.1242/jcs.031286 · External reference
10.1042/bj20050104
10.1042/bj20050104 · External reference
The 'diamond concept' for long bone non-union management
10.1186/s10195-019-0528-0 · 2019 · External reference
Comparison of the clinical effectiveness of Bone Morphogenic Protein (BMP) -2 and -7 in the adjunct treatment of lower limb nonunions
10.1016/j.otsr.2018.08.008 · 2018 · External reference
10.1146/annurev.immunol.19.1.423
10.1146/annurev.immunol.19.1.423 · External reference
10.1172/jci9586
10.1172/jci9586 · External reference
Thrombin inhibits nuclear factor κB and RhoA pathways in cytokine-stimulated vascular endothelial cells when EPCR is occupied by protein C
10.1160/th08-09-0568 · 2009 · External reference
New deals on the transcriptional and posttranscriptional regulation of TRP channel target genes during the angiogenesis of glioma
10.5455/jeim.290711.ir.006 · 2011 · External reference
Involvement of the nuclear factor-κB signaling pathway in the regulation of CXC chemokine receptor-4 expression in neuroblastoma cells induced by tumor necrosis factor-α
10.3892/ijmm.2014.2032 · 2015 · External reference
Inhibition of NF-kappa B activity enhanced apoptosis induced by matrine in hepatocellular carcinoma cells
2007 · External reference
10.1007/s10875-005-8217-6
10.1007/s10875-005-8217-6 · External reference
10.1016/s0736-0266(03)00011-1
10.1016/s0736-0266(03)00011-1 · External reference
10.1016/s0304-419x(00)00002-0
10.1016/s0304-419x(00)00002-0 · External reference
Influence of gender and fixation stability on bone defect healing in middle-aged rats: a pilot study
10.1007/s11999-011-1914-y · 2011 · External reference
Two-week longitudinal survey of bone architecture alteration in the hindlimb-unloaded rat model of bone loss: sex differences
10.1152/ajpendo.00293.2004 · 2006 · External reference
Unresolved reference
External reference
10.1016/j.bone.2021.115883
10.1016/j.bone.2021.115883 · External reference
10.3390/biomedicines6030082
10.3390/biomedicines6030082 · External reference
10.1002/jbmr.3378
10.1002/jbmr.3378 · External reference
Spatial and temporal gene expression for fibroblast growth factor type I receptor (FGFR1) during fracture healing in the rat
10.1016/s8756-3282(01)00604-4 · 2001 · External reference
c-Jun N-Terminal Kinases (JNKs) are critical mediators of osteoblast activity in vivo
10.1002/jbmr.3184 · 2017 · External reference
10.1101/2020.04.04.025700
10.1101/2020.04.04.025700 · External reference
IRS-1 functions as a molecular scaffold to coordinate IGF-I/IGFBP-2 signaling during osteoblast differentiation
10.1002/jbmr.2791 · 2016 · External reference
10.1126/science.1107107
10.1126/science.1107107 · External reference
10.1073/pnas.1111056108
10.1073/pnas.1111056108 · External reference
RhoH GTPase: a key regulator of hematopoietic cell proliferation and apoptosis?
10.4161/cc.4.2.1395 · 2005 · External reference
