Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Privacy-aware community infrastructureResearch graph
References from Structural binding site comparisons reveal Crizotinib as a novel LRRK2 inhibitor. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1016/s1474-4422(18)30499-x
10.1016/s1474-4422(18)30499-x · External reference
10.1016/s0140-6736(14)61393-3
10.1016/s0140-6736(14)61393-3 · External reference
10.1016/s1474-4422(19)30287-x
10.1016/s1474-4422(19)30287-x · External reference
10.1016/j.neuron.2004.11.005
10.1016/j.neuron.2004.11.005 · External reference
10.1007/978-3-319-49969-7_1
10.1007/978-3-319-49969-7_1 · External reference
10.1016/j.expneurol.2017.07.019
10.1016/j.expneurol.2017.07.019 · External reference
10.1038/s41591-020-0893-5
10.1038/s41591-020-0893-5 · External reference
10.1038/s41582-019-0301-2
10.1038/s41582-019-0301-2 · External reference
10.1016/j.jhealeco.2016.01.012
10.1016/j.jhealeco.2016.01.012 · External reference
10.1001/jama.2020.1166
10.1001/jama.2020.1166 · External reference
10.1038/nrd3405
10.1038/nrd3405 · External reference
10.1038/nrd.2018.168
10.1038/nrd.2018.168 · External reference
10.1016/j.csbj.2020.04.004
10.1016/j.csbj.2020.04.004 · External reference
10.1007/978-1-4939-7000-1_26
10.1007/978-1-4939-7000-1_26 · 2017 · External reference
10.1038/s41586-019-1923-7
10.1038/s41586-019-1923-7 · External reference
’it will change everything’: Deepmind’s ai makes gigantic leap in solving protein structures
10.1038/d41586-020-03348-4 · 2020 · External reference
Structure-based drug repositioning: Potential and limits
10.1016/j.semcancer.2020.01.010 · 2021 · External reference
Repositioned drugs for chagas disease unveiled via structure-based drug repositioning
10.3390/ijms21228809 · 2020 · External reference
10.1093/nar/gkv315
10.1093/nar/gkv315 · External reference
Plip 2021: expanding the scope of the protein–ligand interaction profiler to dna and rna
10.1093/nar/gkab294 · 2021 · External reference
Rcsb protein data bank: biological macromolecular structures enabling research and education in fundamental biology, biomedicine, biotechnology and energy
10.1093/nar/gky1004 · 2018 · External reference
10.1016/j.cell.2020.08.004
10.1016/j.cell.2020.08.004 · External reference
10.1038/s41586-020-2673-2
10.1038/s41586-020-2673-2 · External reference
10.1101/676627
10.1101/676627 · External reference
10.1073/pnas.1817889116
10.1073/pnas.1817889116 · External reference
10.1042/bcj20161078
10.1042/bcj20161078 · External reference
Structural characterization of lrrk2 inhibitors
10.1021/jm5018779 · 2015 · External reference
10.1073/pnas.0709098105
10.1073/pnas.0709098105 · External reference
Structure-based drug repositioning explains ibrutinib as vegfr2 inhibitor
10.1371/journal.pone.0233089 · 2020 · External reference
10.1038/srep42717
10.1038/srep42717 · External reference
10.1002/cmdc.201600182
10.1002/cmdc.201600182 · External reference
Pubchem 2019 update: improved access to chemical data
10.1093/nar/gky1033 · 2018 · External reference
Unresolved reference
External reference
10.1021/ci100050t
10.1021/ci100050t · External reference
Comparing structural fingerprints using a literature-based similarity benchmark
10.1186/s13321-016-0148-0 · 2016 · External reference
10.21105/joss.03021
10.21105/joss.03021 · External reference
Uniprot: a worldwide hub of protein knowledge
10.1093/nar/gky1049 · 2018 · External reference
10.1093/nar/gkz268
10.1093/nar/gkz268 · External reference
10.1093/nar/gkz268
10.1093/nar/gkz268 · External reference
Unresolved reference
External reference
10.1038/nbt.2017
10.1038/nbt.2017 · External reference
10.1021/jm401654j
10.1021/jm401654j · External reference
10.1038/nchembio.538
10.1038/nchembio.538 · External reference
10.1042/bj20091035
10.1042/bj20091035 · External reference
Crizotinib
10.1007/978-3-319-91442-8_4 · 2018 · External reference
Paroxetine in parkinson’s disease: Effects on motor and depressive symptoms
10.1212/wnl.55.8.1216 · 2000 · External reference
10.1021/cb3003013
10.1021/cb3003013 · External reference
Vardenafil: a selective inhibitor of phosphodiesterase-5 for the treatment of erectile dysfunction
10.1517/14656566.8.7.965 · 2007 · External reference
10.1016/s0140-6736(17)30703-1
10.1016/s0140-6736(17)30703-1 · External reference
Thyroid hormone level is associated with motor symptoms in de novo parkinson’s disease
10.1007/s00415-015-7780-x · 2015 · External reference
Efavirenz for hiv-1 infection in adults: an overview
10.1586/14789072.2.5.671 · 2004 · External reference
The oral tyrosine kinase inhibitors lapatinib and sunitinib: new opportunities for the treatment of brain metastases from breast cancer?
10.1586/era.10.190 · 2011 · External reference
High-affinity binding of [3h]paroxetine to caudate nucleus and microvessels from porcine brain
10.1097/00001756-199605310-00016 · 1996 · External reference
Cerebrospinal fluid exposure of efavirenz and its major metabolites when dosed at 400 mg and 600 mg once daily: A randomized controlled trial
10.1093/cid/ciu976 · 2014 · External reference
10.1016/j.nlm.2012.02.008
10.1016/j.nlm.2012.02.008 · External reference
Carrier-mediated transport of thyroid hormones through the rat blood-brain barrier: Primary role of albumin-bound hormone
10.1210/endo-105-3-605 · 1979 · External reference
Csf concentration of the anaplastic lymphoma kinase inhibitor crizotinib
10.1200/jco.2010.34.1313 · 2011 · External reference
10.1093/annonc/mdm408
10.1093/annonc/mdm408 · External reference
Sunitinib in kidney cancer: 10 years of experience and development
10.1080/14737140.2017.1272415 · 2017 · External reference
10.1007/s11523-012-0220-2
10.1007/s11523-012-0220-2 · External reference
10.1111/j.1742-4658.2008.06789.x
10.1111/j.1742-4658.2008.06789.x · External reference
10.1021/jm500261q
10.1021/jm500261q · External reference
Lorlatinib: First global approval
10.1007/s40265-018-1041-0 · 2019 · External reference
From malaria to cancer: Computational drug repositioning of amodiaquine using plip interaction patterns
10.1038/s41598-017-11924-4 · 2017 · External reference
Chembl: towards direct deposition of bioassay data
10.1093/nar/gky1075 · 2018 · External reference
’it opens up a whole new universe’: Revolutionary microscopy technique sees individual atoms for first time
10.1038/d41586-020-01658-1 · 2020 · External reference
