Research graph
References from Coarse-grained simulations uncover Gram-negative bacterial defense against polymyxins by the outer membrane. Local targets link to admitted publications; unresolved targets remain external evidence.
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10.1126/science.aax3879 · External reference
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10.1016/s1473-3099(17)30753-3 · External reference
10.1038/s41586-019-1791-1
10.1038/s41586-019-1791-1 · External reference
Polymyxins: a new hope in combating Gram-negative superbugs?
10.4155/fmc-2016-0091 · 2016 · External reference
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10.1093/jac/dkaa376
10.1093/jac/dkaa376 · External reference
Outer membrane interaction kinetics of new polymyxin B analogs in Gram-negative bacilli
10.1128/aac.00935-19 · 2019 · External reference
10.1016/j.bpj.2018.02.006
10.1016/j.bpj.2018.02.006 · External reference
Molecular characterization of the outer membrane of Pseudomonas aeruginosa
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Interaction of the antimicrobial peptide polymyxin B1 with both membranes of E. coli: a molecular dynamics study
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Membrane charge and lipid packing determine polymyxin-induced membrane damage
10.1038/s42003-019-0297-6 · 2019 · External reference
Polymyxins bind to the cell surface of unculturable Acinetobacter baumannii and cause unique dependent resistance
10.1002/advs.202000704 · 2020 · External reference
10.1021/jp071097f
10.1021/jp071097f · External reference
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10.1021/acs.biochem.6b01063 · External reference
10.1002/jcc.24895
10.1002/jcc.24895 · External reference
Role of o-antigen in response to mechanical stress of the E. coli outer membrane: insights from coarse-grained md simulations
10.1021/acs.jpcb.8b12168 · 2019 · External reference
10.1002/jcc.20291
10.1002/jcc.20291 · External reference
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10.1063/1.2408420 · External reference
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10.1074/jbc.ra120.014856 · External reference
g_wham: a free weighted histogram analysis implementation including robust error and autocorrelation estimates
10.1021/ct100494z · 2010 · External reference
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10.1021/acs.jcim.7b00271 · External reference
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Unresolved reference
External reference
10.1038/s41586-018-0344-3
10.1038/s41586-018-0344-3 · External reference
Divalent calcium ions inhibit the penetration of protamine through the polysaccharide brush of the outer membrane of Gram-negative bacteria
10.1021/la030193e · 2003 · External reference
Quantitative determination of ion distributions in bacterial lipopolysaccharide membranes by grazing-incidence X-ray fluorescence
10.1073/pnas.0913737107 · 2010 · External reference
Bacterial lipopolysaccharides form physically cross-linked, two-dimensional gels in the presence of divalent cations
10.1039/c5sm01002k · 2015 · External reference
Effect of calcium and magnesium ions on the susceptibility of Pseudomonas species to tetracycline, gentamicin polymyxin B, and carbenicillin
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10.1021/la504407v
10.1021/la504407v · External reference
Rescuing the last-line polymyxins: achievements and challenges
10.1124/pharmrev.120.000020 · 2021 · External reference
Peptide antibiotics
10.1016/s0140-6736(97)80051-7 · 1997 · External reference
10.1073/pnas.1803975115
10.1073/pnas.1803975115 · External reference
Investigating the interaction of octapeptin A3 with model bacterial membranes
10.1021/acsinfecdis.7b00065 · 2017 · External reference
The Kdo biosynthetic pathway toward OM biogenesis as target in antibacterial drug design and development
10.2174/157016309787581093 · 2009 · External reference
10.3389/fmicb.2014.00643
10.3389/fmicb.2014.00643 · External reference
Structure, function, and biosynthetic origin of octapeptin antibiotics active against extensively drug-resistant Gram-negative bacteria
10.1016/j.chembiol.2018.01.005 · 2018 · External reference