Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Privacy-aware community infrastructureResearch graph
References from Implementing fluorescence enhancement, quenching, and FRET for investigating flap endonuclease 1 enzymatic reaction at the single-molecule level. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1016/j.dnarep.2014.03.022
10.1016/j.dnarep.2014.03.022 · External reference
Double strand binding-single strand incision mechanism for human flap endonuclease: implications for the superfamily
10.1016/j.mad.2011.11.009 · 2012 · External reference
The wonders of flap endonucleases: structure, function, mechanism and regulation
10.1007/978-94-007-4572-8_16 · 2012 · External reference
10.1146/annurev.biochem.73.012803.092453
10.1146/annurev.biochem.73.012803.092453 · External reference
Preparation and crystallization of human flap endonuclease FEN-1 in complex with proliferating-cell nuclear antigen, PCNA
10.1107/s0907444903004815 · 2003 · External reference
10.1016/j.cell.2011.03.004
10.1016/j.cell.2011.03.004 · External reference
10.1016/j.cell.2011.03.005
10.1016/j.cell.2011.03.005 · External reference
Crystal structure of bacteriophage T4 5' nuclease in complex with a branched DNA reveals how flap endonuclease-1 family nucleases bind their substrates
10.1074/jbc.m703209200 · 2007 · External reference
10.7554/elife.12256
10.7554/elife.12256 · External reference
Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA
10.1016/j.celrep.2015.11.042 · 2015 · External reference
Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I
10.1073/pnas.1704845114 · 2017 · External reference
DNA and Protein Requirements for Substrate Conformational Changes Necessary for Human Flap Endonuclease-1-catalyzed Reaction
10.1074/jbc.m115.698993 · 2016 · External reference
10.1038/nmeth.1208
10.1038/nmeth.1208 · External reference
10.1146/annurev-biophys-070816-034106
10.1146/annurev-biophys-070816-034106 · External reference
10.1021/acs.chemrev.9b00361
10.1021/acs.chemrev.9b00361 · External reference
10.1021/acs.chemrev.7b00519
10.1021/acs.chemrev.7b00519 · External reference
10.1063/1.1521158
10.1063/1.1521158 · External reference
10.1063/1.1589587
10.1063/1.1589587 · External reference
10.1073/pnas.96.7.3670
10.1073/pnas.96.7.3670 · External reference
10.1021/ar0401348
10.1021/ar0401348 · External reference
10.1083/jcb.89.1.141
10.1083/jcb.89.1.141 · External reference
10.1034/j.1600-0854.2001.21104.x
10.1034/j.1600-0854.2001.21104.x · External reference
10.1038/nmeth.1215
10.1038/nmeth.1215 · External reference
10.1006/meth.2001.1217
10.1006/meth.2001.1217 · External reference
10.1039/c5cp04137f
10.1039/c5cp04137f · External reference
10.1038/nmeth.3769
10.1038/nmeth.3769 · External reference
Fluorescence Energy-Transfer as a Spectroscopic Ruler
10.1146/annurev.bi.47.070178.004131 · 1978 · External reference
Fluorescence resonance energy transfer between a single donor and a single acceptor molecule
1996 · External reference
10.1073/pnas.93.13.6264
10.1073/pnas.93.13.6264 · External reference
Characterization of photoinduced isomerization and intersystem crossing of the cyanine dye Cy3
10.1021/jp067843i · 2007 · External reference
10.1073/pnas.1017672108
10.1073/pnas.1017672108 · External reference
10.1039/c3cs60201j
10.1039/c3cs60201j · External reference
Single-molecule characterization of Fen1 and Fen1/PCNA complexes acting on flap substrates
10.1093/nar/gkt1116 · 2014 · External reference
10.1126/science.1168352
10.1126/science.1168352 · External reference
10.1038/nature04049
10.1038/nature04049 · External reference
10.1016/j.cell.2006.06.042
10.1016/j.cell.2006.06.042 · External reference
10.1016/j.cell.2010.07.016
10.1016/j.cell.2010.07.016 · External reference
10.1093/nar/gkt554
10.1093/nar/gkt554 · External reference
10.1016/j.chembiol.2017.09.008
10.1016/j.chembiol.2017.09.008 · External reference
10.1039/c2cc33133k
10.1039/c2cc33133k · External reference
10.1021/acs.jpclett.5b00613
10.1021/acs.jpclett.5b00613 · External reference
10.1093/nar/gku199
10.1093/nar/gku199 · External reference
Sequence-dependent fluorescence of Cy3-and Cy5-labeled double-stranded DNA
10.1021/acs.bioconjchem.6b00053 · 2016 · External reference
Initial state of DNA-Dye complex sets the stage for protein induced fluorescence modulation
10.1038/s41467-019-10137-9 · 2019 · External reference
10.1039/c3cs60211g
10.1039/c3cs60211g · External reference
10.1021/cr900343z
10.1021/cr900343z · External reference
10.1016/j.molcel.2009.07.003
10.1016/j.molcel.2009.07.003 · External reference
10.1017/s0033583510000247
10.1017/s0033583510000247 · External reference
10.1016/j.bpj.2011.01.014
10.1016/j.bpj.2011.01.014 · External reference
Mechanism for priming DNA synthesis by yeast DNA polymerase alpha
10.7554/elife.00482 · 2013 · External reference
The p58 subunit of human DNA primase is important for primer initiation, elongation, and counting
10.1021/bi016030b · 2002 · External reference
Slow Joining of Newly Replicated DNA Chains in DNA Polymerase I-Deficient Escherichia-Coli Mutants
10.1073/pnas.68.12.2954 · 1971 · External reference
Structure and processivity of two forms of Saccharomyces cerevisiae DNA polymerase delta
10.1074/jbc.273.31.19756 · 1998 · External reference
10.1101/gad.1252304
10.1101/gad.1252304 · External reference
10.1074/jbc.m109.015065
10.1074/jbc.m109.015065 · External reference
10.1074/jbc.m110662200
10.1074/jbc.m110662200 · External reference
10.1093/emboj/19.14.3811
10.1093/emboj/19.14.3811 · External reference
The pol32 subunit of DNA polymerase delta contains separable domains for processive replication and proliferating cell nuclear antigen (PCNA) binding
10.1074/jbc.m310362200 · 2004 · External reference
10.1080/10409230590935433 · Admitted local publication
The characterization of a mammalian DNA structure-specific endonuclease
10.1002/j.1460-2075.1994.tb06373.x · 1994 · External reference
10.1101/gad.8.11.1344
10.1101/gad.8.11.1344 · External reference
10.1146/annurev-biochem-072511-122603
10.1146/annurev-biochem-072511-122603 · External reference
10.1074/jbc.r110.209502
10.1074/jbc.r110.209502 · External reference
10.1093/nar/gkq884
10.1093/nar/gkq884 · External reference
10.1371/journal.pgen.1003254
10.1371/journal.pgen.1003254 · External reference
10.1371/journal.pone.0179278
10.1371/journal.pone.0179278 · External reference
Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability
10.1038/ncomms15855 · 2017 · External reference
Structural basis of 5' flap recognition and protein-protein interactions of human flap endonuclease 1
10.1093/nar/gky911 · 2018 · External reference
Flap endonuclease 1 mechanism analysis indicates flap base binding prior to threading
10.1074/jbc.m110.165902 · 2010 · External reference
10.1093/nar/gks051
10.1093/nar/gks051 · External reference
Sequential and multistep substrate interrogation provides the scaffold for specificity in human flap endonuclease 1
10.1016/j.celrep.2013.05.001 · 2013 · External reference
Single-molecule FRET unveils induced-fit mechanism for substrate selectivity in flap endonuclease 1
10.7554/elife.21884 · 2017 · External reference
10.1016/s0092-8674(03)01036-5
10.1016/s0092-8674(03)01036-5 · External reference
Structural basis for recruitment of human flap endonuclease 1 to PCNA
10.1038/sj.emboj.7600519 · 2005 · External reference
10.1093/nar/gky082
10.1093/nar/gky082 · External reference
Structure of the processive human Pol delta holoenzyme
10.1038/s41467-020-14898-6 · 2020 · External reference
Versatile single-molecule multi-color excitation and detection fluorescence setup for studying biomolecular dynamics
10.1063/1.3657153 · 2011 · External reference
Relative contributions of base stacking and electrostatic repulsion on DNA nicks and gaps
10.1021/acs.jpcb.0c06941 · 2020 · External reference
Xpg Endonuclease Makes the 3' Incision in Human DNA Nucleotide Excision-Repair
10.1038/371432a0 · 1994 · External reference
Open complex formation around a lesion during nucleotide excision repair provides a structure for cleavage by human XPG protein
10.1093/emboj/16.3.625 · 1997 · External reference
Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations
10.1073/pnas.1921311117 · 2020 · External reference
Human apurinic/apyrimidinic endonuclease 1
10.1089/ars.2013.5492 · 2014 · External reference
A chemical and kinetic perspective on base excision repair of DNA
10.1021/ar400275a · 2014 · External reference
AP-endonuclease 1 Sculpts DNA through an anchoring tyrosine residue on the DNA intercalating loop
2020 · External reference
Resolution of the Holliday junction recombination intermediate by human GEN1 at the single-molecule level
10.1093/nar/gky1280 · 2019 · External reference
10.1038/s41589-018-0209-y
10.1038/s41589-018-0209-y · External reference
10.1093/nar/gkx1216
10.1093/nar/gkx1216 · External reference
10.1016/s0021-9258(17)33357-4
10.1016/s0021-9258(17)33357-4 · External reference
10.1093/nar/gkz797
10.1093/nar/gkz797 · External reference
Rate-determining Step of Flap Endonuclease 1 (FEN1) Reflects a Kinetic Bias against Long Flaps and Trinucleotide Repeat Sequences
10.1074/jbc.m115.666438 · 2015 · External reference
Positioning the 5'-flap junction in the active site controls the rate of flap endonuclease-1-catalyzed DNA cleavage
10.1074/jbc.ra117.001137 · 2018 · External reference
Biochemical analyses indicate that binding and cleavage specificities define the ordered processing of human Okazaki fragments by Dna2 and FEN1
10.1093/nar/gks388 · 2012 · External reference
Observation of unpaired substrate DNA in the flap endonuclease-1 active site
10.1093/nar/gkt737 · 2013 · External reference
Proline Scanning Mutagenesis Reveals a Role for the Flap Endonuclease-1 Helical Cap in Substrate Unpairing
10.1074/jbc.m113.509489 · 2013 · External reference
A conserved loop-wedge motif moderates reaction site search and recognition by FEN1
10.1093/nar/gky506 · 2018 · External reference
Regional conformational flexibility couples substrate specificity and scissile phosphate diester selectivity in human flap endonuclease 1
10.1093/nar/gky293 · 2018 · External reference
10.1038/nsmb.3207
10.1038/nsmb.3207 · External reference
10.1074/jbc.m116.758599
10.1074/jbc.m116.758599 · External reference
Biochemical analysis of human Dna2
10.1093/nar/gkl070 · 2006 · External reference
10.1074/jbc.m006513200
10.1074/jbc.m006513200 · External reference
RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes
10.1038/35086609 · 2001 · External reference
Dna2 nuclease-helicase structure, mechanism and regulation by Rpa
10.7554/elife.09832 · 2015 · External reference
Significance of the dissociation of Dna2 by flap endonuclease 1 to Okazaki fragment processing in Saccharomyces cerevisiae
10.1074/jbc.m809189200 · 2009 · External reference
Flap endonuclease disengages Dna2 helicase/nuclease from Okazaki fragment flaps
10.1074/jbc.m606884200 · 2006 · External reference
Human Fanconi anemia complementation group a protein stimulates the 5' flap endonuclease activity of FEN1
10.1371/journal.pone.0082666 · 2013 · External reference
10.3390/genes8070190
10.3390/genes8070190 · External reference
10.1074/jbc.m103914200
10.1074/jbc.m103914200 · External reference
10.1074/jbc.m806668200
10.1074/jbc.m806668200 · External reference
Structural and thermodynamic analysis of human PCNA with peptides derived from DNA polymerase-delta p66 subunit and flap endonuclease-1
10.1016/j.str.2004.09.018 · 2004 · External reference
Phosphorylation of the p68 Subunit of Pol delta Acts as a Molecular Switch To Regulate Its Interaction with PCNA
10.1021/bi201638e · 2012 · External reference
10.1038/nature10895
10.1038/nature10895 · External reference
10.1016/s0092-8674(00)81347-1
10.1016/s0092-8674(00)81347-1 · External reference
