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References from Application of ensemble pharmacophore-based virtual screening to the discovery of novel antimitotic tubulin inhibitors. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1038/nrd3253
10.1038/nrd3253 · External reference
10.1038/nrc1317
10.1038/nrc1317 · External reference
10.1002/med.21541
10.1002/med.21541 · External reference
10.1038/nrc2803
10.1038/nrc2803 · External reference
10.1021/acs.jmedchem.6b00463
10.1021/acs.jmedchem.6b00463 · External reference
10.1038/nature02393
10.1038/nature02393 · External reference
10.1083/jcb.201211017
10.1083/jcb.201211017 · External reference
The tubulin colchicine domain: a molecular modeling perspective
10.1002/cmdc.201100361 · 2012 · External reference
New ligands of the tubulin colchicine site based on X-ray structures
10.2174/1568026614666141130092637 · 2014 · External reference
A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach
10.1021/jm050502t · 2005 · External reference
Structure-based pharmacophore design and virtual screening for novel tubulin inhibitors with potential anticancer activity
10.3390/molecules24173181 · 2019 · External reference
Common hits approach: combining pharmacophore modeling and molecular dynamics simulations
10.1021/acs.jcim.6b00674 · 2017 · External reference
Virtual screening using pharmacophore models retrieved from molecular dynamic simulations
10.3390/ijms20235834 · 2019 · External reference
10.1016/j.jtbi.2017.11.021
10.1016/j.jtbi.2017.11.021 · External reference
10.1007/s11030-018-9885-5
10.1007/s11030-018-9885-5 · External reference
In silico exploration of vinca domain tubulin inhibitors: a combination of 3D-QSAR-based pharmacophore modeling, docking and molecular dynamics simulations
2017 · External reference
10.1007/s10822-020-00329-7
10.1007/s10822-020-00329-7 · External reference
10.3390/molecules21101375
10.3390/molecules21101375 · External reference
An overview of tubulin inhibitors that interact with the colchicine binding site
10.1007/s11095-012-0828-z · 2012 · External reference
Substructure and whole molecule approaches for calculating log P
10.1023/a:1011107422318 · 2001 · External reference
Unresolved reference
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10.1021/acs.jctc.5b00864
10.1021/acs.jctc.5b00864 · External reference
10.1021/ci049885e
10.1021/ci049885e · External reference
PHASE: a novel approach to pharmacophore modeling and 3D database searching
10.1111/j.1747-0285.2006.00384.x · 2006 · External reference
Pharmer: efficient and exact pharmacophore search
10.1021/ci200097m · 2011 · External reference
Application of the Nosé−Hoover chain algorithm to the study of protein dynamics
10.1021/jp951968y · 1996 · External reference
10.1063/1.467468
10.1063/1.467468 · External reference
10.1109/sc.2006.54
10.1109/sc.2006.54 · External reference
10.1016/0263-7855(96)00018-5
10.1016/0263-7855(96)00018-5 · External reference
Unresolved reference
External reference
10.1021/jm3015603
10.1021/jm3015603 · External reference
10.1016/j.ejmech.2015.05.047
10.1016/j.ejmech.2015.05.047 · External reference
Further naphthylcombretastatins. An investigation on the role of the naphthalene moiety
10.1021/jm0310737 · 2005 · External reference
10.1111/febs.13555
10.1111/febs.13555 · External reference
10.1021/ci049714
10.1021/ci049714 · External reference
10.1038/srep42717
10.1038/srep42717 · External reference
Physiochemical drug properties associated with in vivo toxicological outcomes
10.1016/j.bmcl.2008.07.071 · 2008 · External reference
10.1021/jm000942e
10.1021/jm000942e · External reference
Predicting skin permeability
10.1023/a:1015810312465 · 1992 · External reference
10.1021/jm0492002
10.1021/jm0492002 · External reference
Use of the tetrachlorosilane-sodium azide system for synthesis of tetrazoles from carboxylic acid amides
10.1007/bf02256929 · 2000 · External reference
Practical Asymmetric Synthesis of (S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine- 3,6,10(4H)-trione, a Key Intermediate for the Synthesis of Irinotecan and Other Camptothecin Analogs
10.1021/jo970173f · 1997 · External reference
Tetrachlorosilane-sodium azide system in the synthesis of tetrazole-containing amino acid derivatives
10.1023/a:1021624401405 · 2002 · External reference
10.1073/pnas.70.3.765
10.1073/pnas.70.3.765 · External reference
Different kinetic pathways of the binding of two biphenyl analogues of colchicine to tubulin
10.1021/bi952451f · 1996 · External reference
Microtubule destabilizing sulfonamides as an alternative to taxane-based chemotherapy
10.3390/ijms22041907 · 2021 · External reference
Anti-mitotic activity of colchicine and the structural basis for its interaction with tubulin
10.1002/med.20097 · 2008 · External reference
10.1023/a:1025513106330
10.1023/a:1025513106330 · External reference
Unresolved reference
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10.3390/molecules23051038
10.3390/molecules23051038 · External reference
The latest automated docking technologies for novel drug discovery
2020 · External reference
