Research graph
References from Polyphenols as alternative treatments of COVID-19. Local targets link to admitted publications; unresolved targets remain external evidence.
WHO Declares COVID-19 a Pandemic
2020 · External reference
10.1016/s1473-3099(20)30120-1
10.1016/s1473-3099(20)30120-1 · External reference
Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2
10.15252/embj.2020106275 · 2020 · External reference
10.1038/s41579-020-00468-6
10.1038/s41579-020-00468-6 · External reference
10.1016/j.bmcl.2020.127377
10.1016/j.bmcl.2020.127377 · External reference
Severe acute respiratory syndrome coronavirus 2: from gene structure to pathogenic mechanisms and potential therapy
10.3389/fmicb.2020.01576 · 2020 · External reference
10.1016/j.antiviral.2014.12.015
10.1016/j.antiviral.2014.12.015 · External reference
10.1128/jvi.79.24.15189-15198.2005
10.1128/jvi.79.24.15189-15198.2005 · External reference
Coronavirus protein processing and RNA synthesis is inhibited by the cysteine proteinase inhibitor E64d
10.1006/viro.1995.1123 · 1995 · External reference
10.1021/acsinfecdis.0c00168
10.1021/acsinfecdis.0c00168 · External reference
10.1038/s41586-020-2601-5
10.1038/s41586-020-2601-5 · External reference
10.1016/j.arcmed.2020.09.013
10.1016/j.arcmed.2020.09.013 · External reference
10.1126/science.abb3405
10.1126/science.abb3405 · External reference
Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication
2020 · External reference
10.1126/science.abf1611
10.1126/science.abf1611 · External reference
Unresolved reference
External reference
Evaluation of green tea polyphenols as novel corona virus (SARS CoV-2) main protease (Mpro) inhibitors–an in silico docking and molecular dynamics simulation study
2020 · External reference
Identification of polyphenols from Broussonetia papyrifera as SARS CoV-2 main protease inhibitors using in silico docking and molecular dynamics simulation approaches
2020 · External reference
Identification of dietary molecules as therapeutic agents to combat COVID-19 using molecular docking studies
2020 · External reference
A dietary molecule as potential anti-COVID-19 agent
2020 · External reference
Phenol-explorer: an online comprehensive database on polyphenol contents in foods
10.1093/database/bap024 · 2010 · External reference
10.1021/acs.jctc.5b00864
10.1021/acs.jctc.5b00864 · External reference
10.1093/nar/28.1.235
10.1093/nar/28.1.235 · External reference
10.1007/s10822-007-9133-z
10.1007/s10822-007-9133-z · External reference
Unresolved reference
External reference
10.4155/fmc-2016-0093
10.4155/fmc-2016-0093 · External reference
BindingDB: a web-accessible database of experimentally determined protein-ligand binding affinities
2007 · External reference
10.1002/jcc.21367
10.1002/jcc.21367 · External reference
10.1021/acs.jctc.5b00935
10.1021/acs.jctc.5b00935 · External reference
10.1002/jcc.20945
10.1002/jcc.20945 · External reference
10.1002/jcc.21287
10.1002/jcc.21287 · External reference
Cyanidin 3-rutinoside and cyanidin 3-xylosylrutinoside as primary phenolic antioxidants in black raspberry
10.1021/jf072313k · 2008 · External reference
10.1016/j.bpj.2009.12.4272
10.1016/j.bpj.2009.12.4272 · External reference
10.1074/jbc.m502577200
10.1074/jbc.m502577200 · External reference
Critical assessment of the important residues involved in the dimerization and catalysis of MERS Coronavirus Main Protease
2015 · External reference
10.1016/j.imu.2020.100461
10.1016/j.imu.2020.100461 · External reference
Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease
2020 · External reference
10.1016/s0169-409x(00)00129-0
10.1016/s0169-409x(00)00129-0 · External reference
Prediction of drug solubility from structure
10.1016/s0169-409x(02)00008-x · 2002 · External reference
10.1021/cb500917m
10.1021/cb500917m · External reference
Resveratrol inhibits Epstein Barr Virus lytic cycle in Burkitt’s lymphoma cells by affecting multiple molecular targets
10.1016/j.antiviral.2012.09.003 · 2012 · External reference
Inhibitory effects of resveratrol on the Epstein-Barr virus lytic cycle
10.3390/molecules15107115 · 2010 · External reference
Resveratrol as a novel anti-herpes simplex virus nutraceutical agent: an overview
10.3390/v10090473 · 2018 · External reference
Resveratrol suppresses nuclear factor-B in herpes simplex virus infected cells
10.1016/j.antiviral.2006.06.011 · 2006 · External reference
Polygonum cuspidatum and its active components inhibit replication of the influenza virus through Toll-like receptor 9-induced interferon beta expression
2015 · External reference
10.1128/jvi.05869-11
10.1128/jvi.05869-11 · External reference
10.1128/jvi.03637-13
10.1128/jvi.03637-13 · External reference
Resveratrol inhibits rhinovirus replication and expression of inflammatory mediators in nasal epithelia
10.1016/j.antiviral.2015.08.010 · 2015 · External reference
10.1016/j.bmc.2013.03.027
10.1016/j.bmc.2013.03.027 · External reference
Medicinal herbal extracts of Sophorae radix, Acanthopanacis cortex, Sanguisorbae radix and Torilis fructus inhibit coronavirus replication in vitro
10.3851/imp1615 · 2010 · External reference
Inhibition of SARS-CoV 3C-like protease activity by theaflavin-3,3′- digallate (TF3)
10.1093/ecam/neh081 · 2005 · External reference
10.4103/2225-4110.124335
10.4103/2225-4110.124335 · External reference
10.1016/j.bmc.2010.09.035
10.1016/j.bmc.2010.09.035 · External reference
Antiviral effects of saikosaponins on human coronavirus 229E in vitro
10.1111/j.1440-1681.2006.04415.x · 2006 · External reference
Anti-SARS coronavirus 3C-like protease effects of Isatis indigotica root and plant-derived phenolic compounds
10.1016/j.antiviral.2005.07.002 · 2005 · External reference
10.1016/j.jep.2008.03.018
10.1016/j.jep.2008.03.018 · External reference
Identification of natural compounds with antiviral activities against SARS-associated coronavirus
10.1016/j.antiviral.2005.02.007 · 2005 · External reference
Unresolved reference
External reference
10.1007/s12272-012-0108-9
10.1007/s12272-012-0108-9 · External reference
10.1016/j.bmcl.2009.07.009
10.1016/j.bmcl.2009.07.009 · External reference
10.1016/j.bmcl.2009.02.010
10.1016/j.bmcl.2009.02.010 · External reference
10.1080/14756366.2016.1265519
10.1080/14756366.2016.1265519 · External reference
Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 interaction
10.1016/j.antiviral.2006.04.014 · 2007 · External reference
10.1128/jvi.78.20.11334-11339.2004
10.1128/jvi.78.20.11334-11339.2004 · External reference
Polyphenols enhance the activity of alkylating agents in leukaemia cell lines
10.18632/oncotarget.27068 · 2019 · External reference
Quercetin nanoparticles display antitumor activity via proliferation inhibition and apoptosis induction in liver cancer cells
10.3892/ijo.2017.3886 · 2017 · External reference
Gram (−) microorganisms DNA polymerase inhibition, antibacterial and chemical properties of fruit and leaf extracts of Sorbus acuparia and Sorbus caucasica var. yaltirikii
10.1002/bmc.3901 · 2017 · External reference
Frangulosid as a novel hepatitis B virus DNA polymerase inhibitor: a virtual screening study
10.1007/s40203-018-0047-3 · 2018 · External reference
Elucidating the inhibitory effect of resveratrol and its structural analogs on selected nucleotide- related enzymes
10.3390/biom10091223 · 2020 · External reference
10.1002/cbic.201500284
10.1002/cbic.201500284 · External reference
The sugar moiety is a major determinant of the absorption of dietary flavonoid glycosides in man
10.1080/10715769900301141 · 1999 · External reference
Identification of potential natural inhibitors of SARS-CoV2 main protease by molecular docking and simulation studies
2020 · External reference
10.1073/pnas.0805240105
10.1073/pnas.0805240105 · External reference
10.1016/j.compbiomed.2021.104560
10.1016/j.compbiomed.2021.104560 · External reference
Activity profiling and crystal structures of inhibitorbound SARS-CoV-2 papain-like protease: A frameworkfor anti–COVID-19 drug design
2020 · External reference
